Very happy that NWO supports this major upgrade of our national EM infrastructure. It is great that this initiative got broad support all over NL, and it will EMPower fantastic science - looking forward to that! www.uu.nl/en/news/33-m...

my friend and wonderful colleague Stan is hiring at Genentech in South San Francisco! 🧬 🌉 Biochemist/structural biologist looking for your first position in industry? I can’t recommend working with Stan enough ☺️ please repost for visibility www.linkedin.com/posts/stanis...

Jonas Moecking et al.: Cryo-EM single-particle analysis expanding towards increasingly native samples ##SingleParticleAnalysis##InSitu##CryoEM@uniutrecht@uniutrecht...##IUCrhttps://journals.iucr.org/paper?S2059798325008332

Happy to see this out :) How close does single-particle cryo-EM get to in situ structure determination? In this review, @tzviyazbm.bsky.social and I explore recent examples of studies that we believe push the boundaries of what's possible. #cryo-EM

Repost appreciated: Open #PhDposition in structural virology in my group! Join us in Umeå, Sweden to uncover how arboviruses remodel infected cells. In situ #cryoET and #cryoEM combined with #virology, #cellbiology, and #biophysics. Deadline 7 September. More info: www.carlsonlab.se/join/

I am happy our recent study on the human sperm head-tail junction is now online. We find that SUN5 form an hexagonal lattice at the nuclear membrane, rationalising how mutations in SUN5 lead to infertility. Great work of @cryonas.bsky.social ! www.biorxiv.org/content/10.1...

ASS is short for acephalic spermatozoa syndrome in which head and tail of sperm are detached⛓️‍💥, commonly caused by mutations in the gene encoding for SUN5. Using in situ cryo-ET❄️🔬 we find that SUN5 forms a protein lattice in the nuclear envelope (NE) at the head-tail junction of mammalian sperm.1/4

Asgard archaea have actin - but what about microtubules? Where do they come from? 🧐 Our new paper www.cell.com/cell/fulltex... by @xujwet.bsky.social & @florianwollweber.bsky.social, in collaboration with the Schleper & Wieczorek labs, describes tiny Asgard microtubules! #TeamTomo #ArchaeaSky 1/6

Mature #HIV-1 contains >2000 copies of “spacer peptide 2”, but we didn’t know why. We now see that SP2 binds the matrix protein and triggers the change into its mature arrangement. Summary video from @margotriggi.bsky.social