Tzviya Zeev-Ben-Mordehai
@tzviyazbm.bsky.social
📤 153
📥 78
📝 8
The cellular structural biology of fertilization group
pinned post!
I am happy our recent study on the human sperm head-tail junction is now online. We find that SUN5 form an hexagonal lattice at the nuclear membrane, rationalising how mutations in SUN5 lead to infertility. Great work of
@cryonas.bsky.social
!
www.biorxiv.org/content/10.1...
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SUN5 forms a regular protein lattice reinforcing the sperm head-tail junction
Linker of nucleo- and cytoskeleton (LINC) complexes reside in the nuclear envelope, the double-membrane surrounding the nucleus, where they establish a physical bridge between nucleus and cytoplasm. L...
https://www.biorxiv.org/content/10.1101/2025.07.29.667520v1
about 2 months ago
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I am happy our recent study on the human sperm head-tail junction is now online. We find that SUN5 form an hexagonal lattice at the nuclear membrane, rationalising how mutations in SUN5 lead to infertility. Great work of
@cryonas.bsky.social
!
www.biorxiv.org/content/10.1...
loading . . .
SUN5 forms a regular protein lattice reinforcing the sperm head-tail junction
Linker of nucleo- and cytoskeleton (LINC) complexes reside in the nuclear envelope, the double-membrane surrounding the nucleus, where they establish a physical bridge between nucleus and cytoplasm. L...
https://www.biorxiv.org/content/10.1101/2025.07.29.667520v1
about 2 months ago
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reposted by
Tzviya Zeev-Ben-Mordehai
Daniel Hurdiss
3 months ago
Latest preprint from the lab, many years in the making! By combining
#cryoEM
with
#AlphaFold3
modelling, we propose that norovirus NS3 forms a transmembrane RNA translocase. This could have big implications for our understanding of viral replication & assembly (🧵)
www.biorxiv.org/content/10.1...
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reposted by
Tzviya Zeev-Ben-Mordehai
Rod Mitchell
5 months ago
Amazing meeting amongst great colleagues and friends 🫶🏻. Looking forward to ETW 2027 in Germany 🇩🇪
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I am honoured to receive a Vici grant from the Dutch Research Council to study sperm functional maturition at the female reproductive tract and to study how sperm establish interaction with an egg
www.uu.nl/en/news/nine...
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Nine Utrecht-based researchers receive Vici-grant
The Dutch Research Council (NWO) has awarded Vici grants to nine Utrecht researchers.
https://www.uu.nl/en/news/nine-utrecht-based-researchers-receive-vici-grant
7 months ago
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New year, new publication, new social media platform
www.nature.com/articles/s41...
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Structural diversity of axonemes across mammalian motile cilia - Nature
Cryoelectron microscopy, cryoelectron tomography and proteomics are used to resolve the 96-nm modular repeat of axonemal doublet microtubules from both sperm flagella and epithelial cilia of the ovidu...
https://www.nature.com/articles/s41586-024-08337-5
8 months ago
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