At the #falling walls science summit in #Berlin, quite an experience!!

we just posted our new work on #SRC #kinase led by the superb Prashant Jain 🤩 Inspired by nature, we discover that the length of the catalytic loop and the autophosphorylation site can be engineered to fine-tune downstream pathway activation. 🙏🏻 @oistedu.bsky.social www.biorxiv.org/content/10.1...

In Hong Kong 🇭🇰

BRAVISSIME 🇮🇹🇮🇹🇮🇹🇮🇹🇮🇹🇮🇹

Back in 🇯🇵🥰

Prof. @paolalaurino.bsky.social from OIST’s Protein Engineering & Evolution Unit was chosen as a finalist the Falling Walls #ScienceBreakthrough in Life Sciences for her research on SAR11 bacteria and how they thrive in nutrient-poor oceans. Congratulations! www.oist.jp/news-center/...

No one.

On my way back home after the #GRC Molecular Mechanisms in evolution. It was any first time and it was fantastic!

Yesterday I visited #EPFL, amazing science going on there! Thanks again to @angelasteinauer.bsky.social and her team!

@lowelab.bsky.social @paolalaurino.bsky.social @xujwet.bsky.social @georgiarapti.bsky.social @embl.org @ebi.embl.org @ncmbm.bsky.social @pawelburkhardt.bsky.social @lionlchristiaen.bsky.social @mediacitybergen.no @unibergen.bsky.social @scienceandtechuib.bsky.social

Made in Switzerland 🇨🇭😳

Read the post by @paolalaurino.bsky.social on the @epistimi-stemm.bsky.social blog about @rozforum.bsky.social, which offers great tools for professional development and diversity. See: www.epistimi.org/blog/welcome...

Hardcore #origami, #japan #kids

The first #MSS2025 afternoon session was all about enzyme evolution 👏 @paolalaurino.bsky.social - live from @oistedu.bsky.social, Ida Helene Steen @cdeepsea.bsky.social and Ioannis Riziotis @ebi.embl.org shared their latest work, using very different approaches to this fascinating topic 🤩

I’m with you in spirit!

Super excited to preprint our work on developing a Biomolecular Emulator (BioEmu): Scalable emulation of protein equilibrium ensembles with generative deep learning from @msftresearch.bsky.social ch AI for Science. www.biorxiv.org/content/10.1...

Registration for #MSS2025 closes in 2 days 🚨Join us for an exciting talk by Paola Laurino @paolalaurino.bsky.social from @oistedu.bsky.social, who will present her latest work using chemical approaches and protein engineering to study protein evolution 👏 ➡️ tinyurl.com/yc4jxdvz

Running Heidelberg

Graduation 👨‍🎓 @oistedu.bsky.social ! I am so proud each time

I work with such an amazing group of people, I am so lucky 😊

Mother’s day

#okinawa life

5yrs old soccer shoes

We are pleased to announce that the next speaker in the ProSE seminar series will be Dr. Klara Hlouchova with a talk on "Protein Structure Before LUCA" May 13, 4PM CET Registration link: tinyurl.com/prose-seminar4 Please share!

Today I ate sea cucumber, it was delicious but I had to focus hard to not think what it looks like as an animal…

Just came back from #JST #AcademiaSinica meeting “Protein Science and Engineering in the Next Era” I got to know the amazing work protein scientists are doing in #Taiwan Looking forward to meet them again

Running #Taipei

Great to see our paper on SAR11 SBPs, published in Nature, selected as a 2025 national Frontiers Planet Prize champion!

Back in #Taiwan after 6years:

5yrs old: “they are marrying” ♥️

“DeepMind CEO believes all diseases will be cured in about 10 years”. This is very irresponsible to give false promises like that to a millions of patients. If you are familiar with the complexity of the human diseases you know it's not possible. #unpopularopinion www.cbsnews.com/video/demis-...

It is time to watch the Great Moose Migration. 🇸🇪 www.bbc.com/news/article...

New postdoc position in our lab (2 y+): evolutionary genomics of integrons and MGEs with focus on vibrio-phage interactions. Great environment @pasteur.fr for science, career building. Super collaborators @celineloot.bsky.social @amazeld.bsky.social @fredoleroux.bsky.social 3 weeks to apply!

Insight exhibition of #Okinawa and #Antarctic pics @oistedu.bsky.social

Dating Bacteria is hard due to the lack of maxima. Assuming aerobes likely postdated the GOE gave us better resolved ages, but also surprised us, but not Dr Dayhoff, showing O2 use predated its atmospheric rise by 900 Mys and helped oxygenic photosynthesis to evolve. www.science.org/doi/10.1126/...

In Shanghai airport…killing time

This is what I miss in #Japan

The wonder of #australia

Melbourne (for vacation)

biorxiv.org/content/10.1... Here’s a paper that was many years in the making. The idea that the climate can affect the thermodynamic mechanism of binding due to the temperature dependence of the entropy term is interesting- we see gradual shift in binding mode along evo trajectory…

A new paper from our lab is available at doi.org/10.1101/2025.... The work describes how ArsA, which is involved in arsenic detoxification, utilizes nucleotides to drive dramatic conformational changes—multiple EM structures of a 64kDa protein. Congratulations to Shivansh Mahajan.

Today I met @francesarnold.bsky.social group, honored to show them my science 🤩

Beautiful trees around @caltech.edu

Don’t miss this wonderful Post-doc club ‘Night Science' workshop at Tel Aviv University with the amazingly creative Itai Yanai! Register now at forms.office.com/r/xVhzcHTy1t Senior PhD students are also welcome.

I visited @profbilc.bsky.social lab this afternoon. Super nice and smart students and postdocs, they do some amazing cryoEM project and also got to learn more about cryoEM and resolution…I will use it more in my lab!

Giving a talk at @caltech.edu biochemistry department at 2pm. Come to meet me if you are around there

What do we need for doing good science? François Jacob said it best that we need 'an atmosphere of enthusiasm, lucid criticism, nonconformism, and friendship.' And that's exactly what we had at the Postdoc Night Science NYC club last week at MSK! Join us next time!

We used to go to the cinema very often then because of small kids we gave up, but now they are big enough that we can go all together! The wizard of the big screen

Happy #woman day.. to all the wonderful women I had the opportunity to meet in my life!