Claire O'Callaghan
@claireocallaghan.bsky.social
📤 1184
📥 1203
📝 53
Working in neuroscience etc. Sydney, Australia
reposted by
Claire O'Callaghan
Martin J. Dahl
4 days ago
At
#ICON
? – Join us tomorrow to hear about novel measurement & manipulation approaches for neuromodulatory systems! 🗓️Sept 19, 🕚11:45 am 🏫Room Sé
#ICON2025
#CogNeuro
#AcademicSky
#LocusCoeruleus
#neuroskyence
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Claire O'Callaghan
Johannes Bohacek
5 days ago
🔵 I'm interrupting my social media hiatus to flag this important preprint from the Bruchas lab (is he not on Bluesky!?) together with
@davidweinshenker.bsky.social
. Very difficult experiments to show that dopamine release from LC terminals is independent of VTA 🔥
www.biorxiv.org/content/10.1...
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https://www.biorxiv.org/content/10.1101/2025.09.15.676390v1.full.pdf
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reposted by
Claire O'Callaghan
OHBM Australia
6 days ago
Don't forget! Abstracts due Sept 22 📝 Don’t miss out!
add a skeleton here at some point
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Claire O'Callaghan
DrBreaky
8 days ago
Interested in hippocampal dynamics and their interactions with cortical rhythms? Our physically constrained model of cortico-hippocampal interactions - complete with fast geometrically informed numerical simulation (available at embedded github repo)
www.biorxiv.org/content/10.1...
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Claire O'Callaghan
hakwan lau
9 days ago
www.biorxiv.org/content/10.1...
Representational Geometries of Perception and Working Memory: A Pilot Study Tomoya Nakamura's first fMRI project ... in which we hereby release a preprint as a way of pre-registration 🧠📈
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Representational Geometries of Perception and Working Memory: A Pilot Study
This study aims to compare the neural representational geometry of visual perception and visual working memory using human fMRI. In our pilot experiment, observers viewed a face-scene blended image (s...
https://www.biorxiv.org/content/10.1101/2025.09.07.674590v1
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Claire O'Callaghan
Jakob Hohwy
11 days ago
Come to Melbourne for the 2025 Conference of the Australasian Society for Philosophy and Psychology Check out the great keynotes - submit your abstract Come join this exciting community of researchers Nov 24-25 - Register now!
#philosophy
#neuroskyence
#philsky
sites.google.com/monash.edu/a...
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ASPP 2025 Melbourne
Australasian Society for Philosophy and Psychology 2025 Conference Melbourne, November 24th - 25th, 2025
https://sites.google.com/monash.edu/aspp-2025-melbourne/
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reposted by
Claire O'Callaghan
14 days ago
Of potential interest to those keen on motor control and/or multi-task networks. Congrats to Elom and Eric.
www.biorxiv.org/content/10.1...
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Motor cortex flexibly deploys a high-dimensional repertoire of subskills
Skilled movement often requires flexibly combining multiple subskills, each requiring dedicated control strategies and underlying computations. How the motor system achieves such versatility remains u...
https://www.biorxiv.org/content/10.1101/2025.09.07.674717v1
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reposted by
Claire O'Callaghan
Mehrdad Kashefi
16 days ago
Excited to share my latest work with
@jonathanamichaels.bsky.social
@diedrichsenjorn.bsky.social
&
@andpru.bsky.social
! We asked: How does the motor cortex account for arm posture when generating movement? Paper 👉
www.biorxiv.org/content/10.1...
1/10
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Compositional neural dynamics during reaching
The complex mechanics of the arm make the neural control of reaching inherently posture dependent. Because previous reaching studies confound reach direction with final posture, it remains unknown how...
https://www.biorxiv.org/content/10.1101/2025.09.04.674069v1
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Claire O'Callaghan
Trends in Cognitive Sciences
24 days ago
Online Now: Noradrenaline drives learning across scales of time and neurobiological organisation
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Noradrenaline drives learning across scales of time and neurobiological organisation
The noradrenergic system plays a diverse role in learning, from optimising learning behaviour to modulating plasticity. Work bridging across micro- and macroscale levels is revealing how noradrenaline achieves this diverse role in learning. Through its balance of targeted versus broad modulation of neurons and non-neuronal astrocytes, the noradrenergic system acts across multiple neurobiological and temporal scales to support adaptive learning. With a multiscale organisation that constrains behaviour and brain dynamics based on value-laden information, and the capacity to bridge the fast neural timescales of milliseconds with the slower timescales of natural behaviour, the noradrenergic system acts as an ‘orchestra conductor’ coordinating learning across scales.
http://dlvr.it/TMlvXK
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reposted by
Claire O'Callaghan
Micah G. Allen
20 days ago
New preprint! We are pleased to share our Hierarchical Bayesian framework for Interoceptive Psychophysics! Implemented in rstan, we provide a complete suite of tools spanning model comparison, parameter recovery, multifactor designs, power analysis, and more! 🎯
www.biorxiv.org/content/10.1...
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Claire O'Callaghan
OHBM Australia
20 days ago
🚨🚨🚨 Don't forget our annual meeting is coming up! Registration and abstract submission is open!🚨🚨🚨
add a skeleton here at some point
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Claire O'Callaghan
hakwan lau
21 days ago
does someone good at coding & analysis want to work remotely w/ us in the coming few months (before end of 2025), as a paid consultant? project will be on neurofeedback (fMRI, ECoG, calcium imaging). we'll work towards developing the experiments & analysis pipelines together. if so pls DM me ur CV🧠📈
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Adaptive learning is coordinated across behaviour, time and neurobiology (from synapses and dendrites, to astrocytes and the systems level). If you’ve ever wondered how noradrenaline helps shape these multiscale learning processes, you might like this:
www.cell.com/trends/cogni...
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24 days ago
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reposted by
Claire O'Callaghan
Tara Murphy
28 days ago
The Australasian Dark Sky Alliance have created a petition to get the Aust. Govt to create legislation that limits light pollution and preserve Australia's Dark skies. Important for human health, wildlife and
#Astronomy
! Australians can sign here:
www.aph.gov.au/e-petitions/...
🔭☄️
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e-petitions
e-petitions
https://www.aph.gov.au/e-petitions/petition/EN7346
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OHBM Oz rego + abstracts now open. Get amongst it!
add a skeleton here at some point
28 days ago
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Claire O'Callaghan
OHBM Australia
28 days ago
✨✨ We are excited to announce the OHBM Australian Chapter 2025 Annual Meeting! 🧠🇦🇺 📢 Abstract submissions & registration now OPEN (abstract submission closes September 15th at 5pm) 📍 Melbourne 🏙️☕ 📅 Wednesday, November 12, 2025
ohbm-aus.github.io/posts/2025-a...
We hope to see you there! 🤩
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Claire O'Callaghan
The New Yorker
29 days ago
“The moon, it turns out, is a great place for men.” Nathan Heller reflects on E. B. White’s “perfect paragraph” on the 1969 moon landing.
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Nathan Heller on E. B. White’s Paragraph About the Moon Landing
What sort of response could measure up to the occasion? White’s idea was as simple as it was audacious.
https://www.newyorker.com/magazine/takes/nathan-heller-on-e-b-whites-paragraph-about-the-moon-landing?utm_medium=social&utm_social-type=owned&utm_source=bluesky&mbid=social_bluesky&utm_brand=tny
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reposted by
Claire O'Callaghan
Yohan J John
about 1 month ago
Here's the latest installment in my series on neuroscience and the hyperreal. I look at the potential dangers of "walled garden thinking", and why extensible modeling is important.
open.substack.com/pub/yohanjoh...
#neuroscience
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To model biological neurons, step outside the "walled gardens" of machine learning
Part 3 of a series on neuroscience and the hyperreal, featuring rebound excitation and poor Yorick's skull
https://open.substack.com/pub/yohanjohn/p/to-model-biological-neurons-step?utm_source=share&utm_medium=android&r=fbdb7
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reposted by
Claire O'Callaghan
Alex Fornito
about 1 month ago
Interested in Network hubs, cortical hierarchies, and gradients? Ever wonder where they come from? Check our latest review, where we cover different approaches to mapping hubs, models for their evolution, and mechanisms for how they develop:
osf.io/preprints/os...
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reposted by
Claire O'Callaghan
John Lees
about 1 month ago
My PhD student
@leonielorenz.bsky.social
(with Eva Geissen) has made this nice (free) online course to introduce mathematical modelling for biology:
www.ebi.ac.uk/training/onl...
Including both molecular and epidemiological examples
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Mathematical modelling for biologists - Modelling concepts in biological research
Mathematical modelling for biologists - Modelling concepts in biological research
https://www.ebi.ac.uk/training/online/courses/mathematical-modelling-biologists/#vf-tabs__section--overview
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Position open for a neuroimaging focused postdoc to come work with us in Sydney Feel free to get in touch for a chat if you have any questions about it :)
usyd.wd105.myworkdayjobs.com/en-GB/USYD_E...
about 1 month ago
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reposted by
Claire O'Callaghan
The Organization for Human Brain Mapping
about 1 month ago
The keynote speaker for the OHBM Virtual Satellite Meeting is Dr. Michael Breakspear, @drbreaky.bsky.social! You won’t want to miss his talk – your only chance will be to register and catch it live at 12:00-13:00 UTC on September 11! 🔗
https://humanbrainmapping.org/25SEASIG
#OHBM
#SEASIG
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Claire O'Callaghan
WeRateDogs
about 1 month ago
This is Archibald. He's been holding in a sneeze since last September. Finally let it loose. 13/10 bless you buddy
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reposted by
Claire O'Callaghan
Ben Fulcher
about 1 month ago
Are you interested in our work on complex physical systems and applications (to neural systems)? Wanna join us in Sydney? 🐨 🦘 We have two open positions: 1. Postdoc position:
usyd.wd105.myworkdayjobs.com/USYD_EXTERNA...
2. Fully-funded PhD position:
www.sydney.edu.au/scholarships...
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Postdoctoral Research Associate (Physics)
Full time, 2-year fixed term position with potential to extend. Located on the Camperdown Campus at the School of Physics. Exciting opportunity to conduct research in a world-leading interdisciplinary...
https://usyd.wd105.myworkdayjobs.com/USYD_EXTERNAL_CAREER_SITE/job/Camperdown-Campus/Postdoctoral-Research-Fellow--Physics-_0133282-1
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reposted by
Claire O'Callaghan
Jörn Diedrichsen
about 1 month ago
Impressive new paper by
@nikospriovoulos.bsky.social
. Clearly pushing the limits of what we can do with in-vivo imaging for the highly folded human cerebellum. Especially interesting is the careful characterization of cerebellar vasculature.
www.biorxiv.org/content/10.1...
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Claire O'Callaghan
Guido Meijer
about 2 months ago
🚨Pre-print alert🚨 We stimulated serotonin with optogenetics while doing large-scale Neuropixel recordings across the mouse brain. We found strong widespread modulation of neural activity, but no effect on the choices of the mouse 🐭 How is this possible? Strap in! (1/9) 👇🧵
doi.org/10.1101/2025...
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Serotonin drives choice-independent reconfiguration of distributed neural activity
Serotonin (5-HT) is a central neuromodulator which is implicated in, amongst other functions, cognitive flexibility. 5-HT is released from the dorsal raphe nucleus (DRN) throughout nearly the entire f...
https://doi.org/10.1101/2025.08.01.668048
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reposted by
Claire O'Callaghan
Alex Fornito
about 2 months ago
Interested in cortical wave dynamics? Check out our new preprint led by J Cruddas with
@jchrispang.bsky.social
where review the physics and physiology of cortical waves and their implications for psychological function:
osf.io/preprints/ps...
@nsb-lab.bsky.social
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reposted by
Claire O'Callaghan
Matt Perich
about 2 months ago
Check out our new review/perspective (w/
@juangallego.bsky.social
& Devika Narain) on neural manifolds in the brain! It was a lot of fun to think through these ideas over the past couple of years, and I'm excited it's finally out in the world! 🔗:
www.nature.com/articles/s41...
📄:
rdcu.be/ex8hW
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A neural manifold view of the brain - Nature Neuroscience
Recent advances in neuroscience have revealed how neural population activity underlying behavior can be well described by topological objects called neural manifolds. Understanding how nature, nurture...
https://www.nature.com/articles/s41593-025-02031-z
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reposted by
Claire O'Callaghan
Christoph Miehl
about 2 months ago
Excited to share our new preprint in which we propose a biologically plausible mechanistic solution to the problem of how the brain can flexibly learn and store new representations without forgetting previously learned information.
www.biorxiv.org/content/10.1...
Detailed 🧵 below 👇 1/12
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Assembly-based computations through contextual dendritic gating of plasticity
Neuronal assemblies — groups of strongly connected neurons — are considered the basic building blocks of perception and memory in the brain by encoding representations of specific concepts. Despite re...
https://www.biorxiv.org/content/10.1101/2025.07.22.666089v1
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reposted by
Claire O'Callaghan
Danai Riga
2 months ago
Beyond happy & proud to have our paper on peptidergic neuromodulation of the
#LC
out! This is a project that started with naive intentions & silly curiosity, withstood 1 pandemic & 2 lab moves & made us fall in ❤️ with the most beautiful brain regions of all!! 🔵
www.science.org/doi/10.1126/...
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Neuropeptide Y neurons surrounding the locus coeruleus inhibit noradrenergic system activity to reduce anxiety
Endogenous neuropeptide Y signaling modulates locus coeruleus activity, promoting adaptive responses to stress.
https://www.science.org/doi/10.1126/sciadv.adq0011
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reposted by
Claire O'Callaghan
Ben Fulcher
2 months ago
New paper! We introduce an efficient set of statistical features for fMRI time series (calibrated on mouse manipulation experiments and tested on mouse and human data): catchaMouse16. Paper:
doi.org/10.52294/001...
Code (python/Matlab/C):
github.com/DynamicsAndN...
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reposted by
Claire O'Callaghan
Tara Murphy
2 months ago
If you missed Katie Mack's Sydney Ideas talk "The End of Everything" you can watch it now on YouTube. Find out about the big rip, heat death and vacuum decay - just some of the ways the Universe might end.
#Physics
#Astronomy
www.youtube.com/watch?v=is8j...
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reposted by
Claire O'Callaghan
Australian Academy of Science
2 months ago
Are you a top US-based scientist wanting to relocate to Australia? We are now calling for formal applications from both Australian and non-Australian citizens based in the US whose work is internationally recognised as exceptional. 📅 Applications close: Aug 29, 2025 🔗
science.org.au/gtap/?utm_so...
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Claire O'Callaghan
Jaan Aru
2 months ago
We systematically reviewed 23 in vitro and 26 in vivo electrophysiological studies on psychedelic compounds, with an emphasis on layer 5 pyramidal neurons. Our results challenge the simplified view that psychedelics uniformly increase cortical excitability
www.biorxiv.org/content/10.1...
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Claire O'Callaghan
Dr. Jan Zimmermann
2 months ago
www.cell.com/cell/abstrac...
!!!
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Single-neuron projectomes of macaque prefrontal cortex reveal refined axon targeting and arborization
The reconstruction of whole-brain projectomes of 2,231 single neurons from the macaque prefrontal cortex reveals refined axon targeting and arborization, providing a structural foundation for primate-...
https://www.cell.com/cell/abstract/S0092-8674(25)00639-7
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reposted by
Claire O'Callaghan
Steven Strogatz
3 months ago
My latest for
@nytimes.com
-- please repost so your followers can see this for free.
www.nytimes.com/interactive/...
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How a Puzzle About Fractions Got Brain Scans Rolling (Gift Article)
A story of bowling pins, patterns and medical miracles.
https://www.nytimes.com/interactive/2025/06/30/science/math-strogatz-calculus-bowling.html?unlocked_article_code=1.S08.U_R_.jlgZk056vHfc&smid=url-share
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Claire O'Callaghan
Seán Froudist-Walsh
3 months ago
Textbook neuroscience teaches that anatomy dictates function. But which aspects of anatomy determine differences in function between species? We think neuroscience is now well-placed to tackle this question. Here is our attempt at one piece of the puzzle:
www.nature.com/articles/s42...
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Higher dopamine D1 receptor expression in prefrontal parvalbumin neurons underlies higher distractibility in marmosets versus macaques - Communications Biology
Integrative anatomical, molecular, behavioral, and modeling evidence suggests that higher dopamine D1 receptor expression in prefrontal cortical parvalbumin neurons in marmosets likely contributes to ...
https://www.nature.com/articles/s42003-025-08297-0
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reposted by
Claire O'Callaghan
Marta Silva
3 months ago
🧠 Paper out! We investigated how hippocampal and cortical ripples support memory during movie watching. We found that: 🎬 Hippocampal ripples mark event boundaries 🧩 Cortical ripples predict later recall Ripples may help transform real-life experiences into lasting memories!
rdcu.be/eui9l
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Movie-watching evokes ripple-like activity within events and at event boundaries
Nature Communications - The neural processes involved in memory formation for realistic experiences remain poorly understood. Here, the authors found that ripple-like activity in the human...
https://rdcu.be/eui9l
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Claire O'Callaghan
Adrien Peyrache
3 months ago
🧠🔬 This important study demonstrates that slow fluctuations in serotonin release during wakefulness and non-REM sleep correspond to periods of heightened arousal or enhanced offline information processing, especially in the hippocampus. Congrats to the authors!
elifesciences.org/reviewed-pre...
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Ultraslow serotonin oscillations in the hippocampus delineate substates across NREM and waking
https://elifesciences.org/reviewed-preprints/101105
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reposted by
Claire O'Callaghan
Nikos Priovoulos
3 months ago
and yet one more: routine cerebellar neuroimaging at 9.4T—no individual B1+ calibration, robust BOLD. A glimpse of what’s to come at even higher fields. in MRM
onlinelibrary.wiley.com/doi/10.1002/...
with Wietske van der Zwaag,
@highonfield.bsky.social
, Desmond Tse 🎓🧠
#fMRI
#cerebellum
#9.4T
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https://doi.org/10.1002/mrm...
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Claire O'Callaghan
Edvard I Moser
3 months ago
Your brain doesn’t just passively track time ⏳ - it structures it. In
@Science.org
we show that activity in 🧠 memory circuits (LEC) drifts constantly, but makes sharp jumps at key moments, segmenting life into meaningful events. (1/2) 👉
www.science.org/doi/10.1126/...
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Event structure sculpts neural population dynamics in the lateral entorhinal cortex
Our experience of the world is a continuous stream of events that must be segmented and organized at multiple timescales. The neural mechanisms underlying this process remain unknown. In this work, we...
https://www.science.org/doi/10.1126/science.adr0927
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Claire O'Callaghan
Mac Shine
3 months ago
Another great article from
@thetransmitter.bsky.social
and Laura Lewis, who has been working painstakingly over the last few years to help ramp up the spatiotemporal resolution of fMRI so that we can really start to dig into whole-brain signals in vivo.
add a skeleton here at some point
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Claire O'Callaghan
OHBM Australia
3 months ago
Come down to the OHBM Australia Chapter desk for koalas, both in fluffy toy and chocolate form!
@ohbmofficial.bsky.social
@ohbmtrainees.bsky.social
@ohbmenvironment.bsky.social
@ohbm-com.com
@ohbmossig.bsky.social
#OHBM
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Claire O'Callaghan
Ben Fulcher
3 months ago
New preprint! Why are long-range connectomic interactions in the cortex dominant in shaping dynamics in some experiments but apparently negligible in others? We (w/ R Maran,
@elimuller.bsky.social
) address this question by studying a new hybrid model of cortical dynamics.
arxiv.org/abs/2506.19800
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Claire O'Callaghan
Alex Fornito
3 months ago
Going to
#ohbm2025
? Be sure to check out our work from
@nsb-lab.bsky.social
. Peep the thread for an overview!
add a skeleton here at some point
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Claire O'Callaghan
Brain and Sleep Research Laboratory
3 months ago
A time window for memory consolidation during NREM sleep revealed by cAMP oscillation: Neuron
www.cell.com/neuron/fullt...
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A time window for memory consolidation during NREM sleep revealed by cAMP oscillation
Sleep is crucial for memory formation. Deng et al. find that cAMP levels in mice oscillate with a 1-min cycle during slow-wave sleep, and hippocampal activity at the peak of these oscillations is nece...
https://www.cell.com/neuron/fulltext/S0896-6273%2825%2900220-X
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Claire O'Callaghan
Marcella Montagnese
3 months ago
New preprint out! We mapped brain vulnerability in Alzheimer’s using MIND networks + population modelling. Put this together with a brilliant team
@raibethlehem.bsky.social
@sarahmorganuk.bsky.social
and many more still making their way to Bluesky 🧠
doi.org/10.1101/2025.06.10.25328978
add a skeleton here at some point
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Claire O'Callaghan
Ann-Sophie Barwich
4 months ago
Updated preprint: "Wider than the Sky: An Alternative to “Mapping” the World onto the Brain" (with Stuart Firestein, Columbia | Biology, and Michael Dietrich, Pittsburgh, History and Philosophy of Science) LINK:
osf.io/preprints/ps...
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Claire O'Callaghan
Sofie Valk
4 months ago
We are seeking a scientific coordinator for my research group at the Max Planck Institute for Human Cognitive and Brain Sciences in Leipzig 😊🧠🌈 Could be ideal for a gap year between MSc and PhD or PhD and postdoc! Please out more here:
recruitingapp-5218.de.umantis.com/Vacancies/43...
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Scientific Coordinator (m/f/d) Part-time (50%) | Karriereportal Max-Planck-Institut für Kognitions- und Neurowissenschaften
Scientific Coordinator (m/f/d) Part-time (50%) | Karriereportal Max-Planck-Institut für Kognitions- und Neurowissenschaften
https://recruitingapp-5218.de.umantis.com/Vacancies/431/Description/2/Default
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Claire O'Callaghan
Vincent Breton-Provencher
4 months ago
My laboratory at Université Laval in Québec City, Canada, is looking for a postdoc to study how neuromodulatory systems impact cortical processing during foraging behavior. This fully-funded position offers a collaborative environment in a great city. More info👇
can-acn.org/postdoctoral...
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Postdoctoral position available in the Breton-Provencher Lab at Université Laval to study neuromodulatory systems and foraging behavior – Canadian Association for Neuroscience
https://can-acn.org/postdoctoral-position-available-in-the-breton-provencher-lab-at-universite-laval-to-study-neuromodulatory-systems-and-foraging-behavior/
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