Such an absolute honour 🙏 Thank You @bscb-official.bsky.social Incredibly lucky to be surrounded by the most supportive colleagues and community. This award truly belongs to my wonderful, wonderful lab @crick.ac.uk

🚨Do sign up to our mailing list for this very exciting joint talk by Profs Marino Arroyo and Xavier Trepat on active morphogenesis on Wednesday 21st Jan🚨

1. Excited to share CONCORD, out in @NatureBiotech, an ML framework for single-cell analysis addressing integration, dimensionality reduction, and denoising in one go by @qinzhu1.🔗 www.nature.com/articles/s41... Check out this CONCORD model of worm development resolving differentiation trajectories:

Mind blown 🤯

We are all super happy and proud to see our work on the function and evolution of the #cephalic #furrow published in @nature.com. Let me say a few things about the background and history of this work on the #Evolution_of_Morphogenesis (1/12)

How do #stemcells integrate information to coordinate fate decisions? Delighted to finally see our work showing how growth factors regulate the mechano-osmotic state of the #nucleus and #chromatin to control #pluripotency exit out! www.nature.com/articles/s41... see 🧵 👇

First, check out my recent bioRxiv preprint w/ @oweinerlab.bsky.social: www.biorxiv.org/content/10.1... We find contractility shifts the proportion of implantation-competent embryos from young and aged females. Keep reading this for more info!

Very excited to be co-organizing this meeting next February. Fellow collective behavior enthusiasts, this one is for you!

Aria Huang's @azyhuang.bsky.social paper is out on beautiful embryonic kidney 3D cultures that branch properly and enable live defect analysis. She also finds intriguing effects of adhesion and stiffness on explant size, shape, and nephron formation - boundary conditions matter! rdcu.be/eBSUK

🔔 Proud to share the preprint of my PhD work in the Petridou group @nicolettapetridou.bsky.social @embl.org ✨ “A closed feedback between tissue phase transitions and morphogen gradients drives patterning dynamics” 🐟 🔁 📶 🔗 www.biorxiv.org/content/10.1... #devbio #biophysics 🧵⤵️

One month left for ECRs to apply for a funded place at our Workshop 'New Technologies for Studying and Reprogramming Development' organised by Alex Dunn, @zevgartner.bsky.social , @adrianjacobo.bsky.social and Matthew Kutys. 📆Apply by 23 May biologists.com/workshops/no... #BiologistsWorkshops

Join us for our next #ForceTalk on "Mechanics of blastocyst morphogenesis" with Dr Jean-Leon Maitre @maitrejl.bsky.social of Institut Curie: 🗓️ 7 May 2025 🕒 15:00 - 16:00 BST Online and open to all, link to join 👉 www.kcl.ac.uk/events/force... #mechanobiology @kingsnmes.bsky.social

Early-career researchers can apply for a funded place at our Workshop 'New Technologies for Studying and Reprogramming Development' organised by Alex Dunn, @zevgartner.bsky.social , @adrianjacobo.bsky.social and Matthew Kutys. 📆Apply by 23 May biologists.com/workshops/no... #BiologistsWorkshops

Many congratulations to @jcornwallscoones.bsky.social on the award of a Schmidt Science Fellowship Now he just needs to find a lab to host him for his post-doc www.crick.ac.uk/news/2025-04...

Since I started my PhD in 2013, I have been tantalised by a question: can we measure or evaluate the transcriptional and mechanical states of cells in a tissue at the same time? I pursued this question as a postdoc and then as a PI! A🧵on the answer we have found 👇:

1. Struggling to integrate single-cell datasets? Finding it hard to resolve clear differentiation trajectories? Reveal the underlying structure in your data with CONCORD.

Excited to share my latest work with @joadelas.bsky.social and @jamesbriscoe.bsky.social Predictable Engineering of Signal-Dependent Cis-Regulatory Elements www.biorxiv.org/content/10.1... 1/11

Congratulations Laura Avinyo! @lauavinyo.bsky.social and Heura Cardona! First paper of your PhD 🎉. doi.org/10.1242/dev.... Beautiful quantified trajectory of how the skeletal pattern of the gene Sox9 emerges during limb development. @embl.org @barcelonacollaboratorium.com

Really excited to present the results of a great collaboration between our group @poldresden.bsky.social and Elliot Hawkes at @ucsantabarbara.bsky.social, which were just published in @science.org. A mix of physics, biology and robotics! 🤖 😀 ▶️ www.science.org/doi/10.1126/...

Excited that our new lab website is starting to come together - thanks to the team, particularly Pauline Marangoni and Zhulin Dixon, for assembling this, and stay tuned for additional updates ophirkleinlab.org

Aria Huang's @azyhuang.bsky.social pre-print just came out on effects of adhesion and stiffness on global kidney explant size, shape and nephron forming efficiency. Along the way, she achieves beautiful 3D cultures that retain proper branching geometry, check it out! biorxiv.org/cgi/content/...

Co-organizing the GRC Mammary Gland Biology and Neoplasia meeting this coming spring in Maine with Traci Lyons. Submit your abstracts for short talk consideration! www.grc.org/mammary-glan...

Pre-announcing the EMBO/EMBL symposium "Mechanobiology Across the Tree of Life", Heidelberg, 9-12 June 2026. It is still very very far away, but save the date 🗓️. With Alba Diz-Munoz, @nicolettapetridou.bsky.social , Kirsty Wan @micromotility.bsky.social, Enrique Rojas. www.embl.org/about/info/c...

My first post on @bsky.app. So happy to announce that our work has been published in Development by @biologists.bsky.social doi.org/10.1242/dev.... Also a big thanks for "The people behind the papers" article as well! doi.org/10.1242/dev....

Right on the $$$

Hello world!