@ophirklein.bsky.social
📤 159
📥 71
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reposted by
Save Our Cures
5 days ago
YOUR PHONE EXISTS because the government invested in "useless" basic research decades ago! It's the same with medical research - today's basic science leads to tomorrow's life-saving treatments. Visit FundResearch.org to tell Congress to keep funding research
#SaveOurCures
#PhoneForGood
#FundNIH
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reposted by
Save Our Cures
about 1 month ago
🎉 INTRODUCING
#SaveOurCures
🎉 Federal biomedical research represents less than 1% of the federal budget but delivers life-saving treatments for millions of American families. 93% of cancer treatments started with American government-funded research. 🧵: 1/8
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Trump Is Shutting Down the War On Cancer
www.nytimes.com/2025/09/14/m...
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Trump Is Shutting Down the War On Cancer
https://www.nytimes.com/2025/09/14/magazine/cancer-research-grants-funds-trump.html?smid=nytcore-ios-share&referringSource=articleShare
16 days ago
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www.nytimes.com/2025/09/08/o...
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Opinion | We Are Watching a Scientific Superpower Destroy Itself
https://www.nytimes.com/2025/09/08/opinion/universities-science-trump-china.html?smid=nytcore-ios-share
21 days ago
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We're very excited to launch a search for a founding director of our new reproductive sciences program at Cedars-Sinai!
careers.cshs.org/job/los-ange...
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Director, Reproductive Sciences Program at CEDARS-SINAI
Learn more about applying for Director, Reproductive Sciences Program at CEDARS-SINAI
https://careers.cshs.org/job/los-angeles/director-reproductive-sciences-program/252/85469306800
about 1 month ago
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reposted by
American Society of Human Genetics (ASHG)
about 1 month ago
🎖️Congratulations to Carole Ober, PhD, winner of the ASHG 2025 Mentorship Award! Learn more about the award and Dr. Ober's work: https://www.ashg.org/membership/awards/2025-awardees/
#ASHG
#HumanGenetic
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reposted by
Camp Lab
about 1 month ago
Final version
@science.org
"Recent evolution of the developing human intestine affects metabolic and barrier functions". Evolutionary preparation for microbiota, diet, and pathogen exposure is fascinating! Thank you
@erc.europa.eu
for supporting our vision!
www.science.org/doi/10.1126/...
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reposted by
Holly Ober
about 2 months ago
UCLA professor Bill Lowry: My current basic-research grant from the National Institutes of Health, which is a continuation of the work that led to this discovery on alopecia, was suspended last week. I don’t know what interesting discoveries won’t be made the longer this thing stays suspended. 🧪
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The Great Unbalding Draws Nearer
Decades of science have not found a way to regrow lost hair. Until, maybe, now.
https://nymag.com/intelligencer/article/pp405-baldness-cure-hair-loss-treatment-follicles-science-tressless.html
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Excited to share our new paper by Jessi Cook in collaboration with Michelle Griffin from Mike Longaker's group at Stanford.
www.science.org/stoken/autho...
As nicely described by our communications team:
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Growth arrest specific–6 and angiotoxin receptor–like signaling drive oral regenerative wound repair
Activation of angiotoxin receptor–like signaling and suppression of focal adhesion kinase allow for regenerative healing in the oral mucosa.
https://urldefense.com/v3/__https://www.science.org/stoken/author-tokens/ST-2728/full__;!!LQC6Cpwp!r2WCyCbcewDxPUoZ7OP1RFv3I1a5Meff6dhv2B9MHoAsDrPsTv5Zm_JVIm0diox7FQ8lGjdEnq6FwZhQ$
3 months ago
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Join us in Crete in the fall to discuss stem cells! The early bird deadline has been extended to July 15th. This date will be the final deadline for abstracts being considered for short talk selection.
www.aegeanconferences.org/src/App/spea...
Looking forward to seeing you there!
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Aegean Conferences
https://www.aegeanconferences.org/src/App/speakers/189”
3 months ago
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reposted by
Waggoner Lab
3 months ago
Activation of angiotoxin receptor–like signaling and suppression of focal adhesion kinase allow for regenerative healing in the oral mucosa
www.science.org/doi/10.1126/...
@ophirklein.bsky.social
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Here Is All the Science at Risk in Trump’s Clash With Harvard
www.nytimes.com/interactive/...
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Here Is All the Science at Risk in Trump’s Clash With Harvard
More than 900 research grants worth $2.6 billion are in jeopardy. So is the 80-year-old model of American science.
https://www.nytimes.com/interactive/2025/06/22/upshot/harvard-funding-cuts.html?smid=nytcore-ios-share&referringSource=articleShare
3 months ago
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Help Save the NIH
www.congressweb.com/UCSF/9?frame...
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Help Save the NIH
As the second largest recipient of NIH funding in the nation, UCSF depends on NIH funding to support our researchers in advancing health worldwide. Unfortunately, the White House's budget request pr...
https://www.congressweb.com/UCSF/9?framed_parent_url_id=DF981716-F3F0-A537-9CBCC41881BE30CA
3 months ago
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reposted by
Ardem Patapoutian
4 months ago
Talked to @KateZernike at @nytimes about my journey and the current moment for scientists in the U.S. “Ardem Patapoutian’s story is not just the American dream, it is the dream of American science.” Read the article here. No subscription required:
www.nytimes.com/2025/06/03/u...
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The U.S. Lit a Beacon for Science. Under Trump, Scientists Fear It’s Dimming
https://www.nytimes.com/2025/06/03/us/trump-federal-spending-grants-scientists-leaving.html?unlocked_article_code=1.ME8.3jjH.HvyxcdgtxpRw
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www.nytimes.com/2025/06/03/u...
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The U.S. Lit a Beacon for Science. Under Trump, Scientists Fear It’s Dimming
https://www.nytimes.com/2025/06/03/us/trump-federal-spending-grants-scientists-leaving.html?smid=nytcore-ios-share
4 months ago
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www.nytimes.com/2025/05/19/o...
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Opinion | In the Future, China Will Be Dominant. The U.S. Will Be Irrelevant.
https://www.nytimes.com/2025/05/19/opinion/china-us-trade-tariffs.html?smid=nytcore-ios-share
4 months ago
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reposted by
Ursula von der Leyen
5 months ago
Europe’s choice is clear. To put science at the heart of its economy. To become the home of scientific freedom and collaboration. And to welcome talent from all over the world. I’m glad to present the first elements of our Choose Europe Initiative. →
europa.eu/!TTbWbJ
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Urge Congress to Reject the President's Budget Proposal to Cut NIH, NSF
www.congressweb.com/ASHG/32?fram...
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Urge Congress to Reject the President's Budget Proposal to Cut NIH, NSF
Earlier today on May 2, the Trump Administration proposed sweeping cuts across the U.S. Department of Health and Human Services (HHS), including a nearly 40% cut to the National Institutes of Health (...
https://www.congressweb.com/ASHG/32?framed_parent_url_id=EE12DB3C-BFF1-260C-ED9AEE895D28AE91
5 months ago
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This is something I keep asking myself:
www.nytimes.com/2025/04/11/o...
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Opinion | What Is Actually the Point of Treating the N.I.H. Like This?
Efficiency is not being enhanced, nor is waste being eliminated at the N.I.H. Scientists are just left to wonder: Why?
https://www.nytimes.com/2025/04/11/opinion/nih-scientists-staffing-cuts.html
6 months ago
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It was an honor to speak at the Shanthi Sitaraman Symposium at Emory yesterday, and to hear about Shanthi from her colleagues, friends and family. She was a remarkable physician, scientist and teacher.
6 months ago
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rarediseases.org/ceo-statemen...
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NORD CEO Statement on the Termination of the Advisory Committee on Heritable Disorders in Newborns and Children - National Organization for Rare Disorders
The sudden termination of the Advisory Committee on Heritable Disorders in Newborns and Children (ACHDNC) raises serious concerns for the rare disease community and families nationwide.
https://rarediseases.org/ceo-statement-on-termination-of-achdnc/
6 months ago
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www.nytimes.com/2025/04/03/o...
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Opinion | The Uncertain Fate of the Young American Scientist
Young researchers are choosing between staying in science and staying in the United States.
https://www.nytimes.com/2025/04/03/opinion/young-american-scientists.html?smid=nytcore-ios-share
6 months ago
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Was great to visit
@newyorkuniversity.bsky.social
dental school today and to hear all the terrific science going on. A highlight of the trip was spending time with our former lab member
@rkzwick.bsky.social
in her beautiful new space and meet her growing group - she is off to a great start!
6 months ago
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reposted by
Jeff Bush
6 months ago
Just recruited two more grad students to be appreciated on Bluesky!
@jasminegarciia.bsky.social
@davidsungtooth.bsky.social
@ophirklein.bsky.social
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Killing the goose that lays the golden eggs
www.nytimes.com/2025/03/31/b...
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Trump’s Science Policies Pose Long-Term Risk, Economists Warn
Since World War II, U.S. research funding has led to discoveries that fueled economic gains. Now cutbacks are seen as putting that legacy in jeopardy.
https://www.nytimes.com/2025/03/31/business/economy/trump-research-cutbacks-economy.html?smid=nytcore-ios-share
6 months ago
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Was great to hear
@ardemp.bskyverified.social
's lecture
@cedars-sinai.bsky.social
annual research day - amazing science and a remarkable life journey. He's so committed to understanding Piezo proteins that he got one tattooed on his arm!
6 months ago
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reposted by
Carolyn Bertozzi
7 months ago
Thank you for lending your voice to
@standupforscience.bsky.social
🙏
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Save the date: The 6th Int’l Conference on Stem Cells will be held at the Kalimera Kriti Hotel in Sissi, Crete, Greece from October 1-6, 2025. Looking forward to our next iteration of this exciting and fun meeting!
www.aegeanconferences.org/src/App/conf...
7 months ago
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Appreciate NIDCR highlighting our paper from last year in this nice piece:
www.nidcr.nih.gov/news-events/...
NIDCR support has been fundamental to our work since we began in this field, and its continued survival is essential to supporting essential dental, oral and craniofacial research
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The Forces that Sculpt a Tooth
Multiplying cells create pressure that triggers the formation of command centers that direct tooth formation in mice, according to an NIDCR-funded study.
https://www.nidcr.nih.gov/news-events/nidcr-news/forces-sculpt-tooth?j=23201&sfmc_sub=7895658&l=1223_HTML&u=398810&mid=546005781&jb=6
7 months ago
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reposted by
Eric Topol
7 months ago
Francis Collins, the NIH Director for 12 years, led the Human Genome Project and other NIH efforts for 32 years, resigned today. Key words from his resignation letter
www.nytimes.com/2025/03/01/u...
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Looking forward to this!
add a skeleton here at some point
8 months ago
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This is sobering:
kucharski.substack.com/p/the-bigges...
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The biggest coincidence of my career
Why we struggle to grasp how bad events will be
https://kucharski.substack.com/p/the-biggest-coincidence-of-my-career
8 months ago
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www.nytimes.com/2025/02/14/o...
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Opinion | American Science is Under Attack
The Trump administration hobbles research and endangers the public health.
https://www.nytimes.com/2025/02/14/opinion/trump-public-health-funding-nih.html?smid=nytcore-ios-share
8 months ago
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reposted by
JAMA
8 months ago
Viewpoint: Recent disruptions and funding cuts at the National Institutes of Health (NIH) undermine the infrastructure and stability of US scientific research, threatening the nation's global leadership and scientific productivity.
ja.ma/41hBnoc
#MedSky
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reposted by
American Society of Human Genetics (ASHG)
8 months ago
ASHG is concerned about the cuts to NIH-funded research support, its impacts on biomedical research, and the effect on local, state, and national economies. We join our advocacy partners to ensure essential progress is not stalled. Read our statement:
www.ashg.org/publications...
#ASHG
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Research Funding at Stake: Urgent Advocacy Needed for NIH Indirect Cost Policy
www.congressweb.com/ASHG/31?fram...
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Research Funding at Stake: Urgent Advocacy Needed for NIH Indirect Cost Policy
UPDATE: On February 10, the attorneys general of 22 states filed a lawsuit (https://www.azag.gov/press-release/attorney-general-mayes-sues-trump-administration-defunding-medical-and-public-health) aga...
https://www.congressweb.com/ASHG/31?framed_parent_url_id=C0234EBC-9800-DC95-173D251A797F755C
8 months ago
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February is Ectodermal Dysplasias Awareness Month! Please help to spread the word
nfed.org/get-involved...
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February is Ectodermal Dysplasias Awareness Month
Ectodermal Dysplasia Awareness begins with YOU! Each February, we come together to celebrate Ectodermal Dysplasias Awareness Month—a time to amplify
https://nfed.org/get-involved/raise-awareness/ectodermal-dysplasias-awareness-month/
8 months ago
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Excited that our new lab website is starting to come together - thanks to the team, particularly Pauline Marangoni and Zhulin Dixon, for assembling this, and stay tuned for additional updates
ophirkleinlab.org
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Home - Klein Lab
We are interested in understanding how organs form in the embryo and how they renew and regenerate in the adult. We research how development and regeneration
https://ophirkleinlab.org/
8 months ago
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Happy birthday Pauline! And welcome Jose Tomas to the lab!
8 months ago
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The devastating wildfires in LA have taken an enormous toll on our community. Even those not directly impacted have had the air they breath affected - our colleague Dr. Dralyuk
@cedars-sinai.bsky.social
Guerin Children's offers some advice here:
www.cedars-sinai.org/newsroom/los...
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Los Angeles County Wildfires: Cedars-Sinai Lung Specialists
Updated Jan. 8, 2025 at 2 p.m. PSTÂ The catastrophic wildfires raging throughout Los Angeles County present special concerns for adults and children with respiratory illnesses. Irina Dralyuk, MD, a Ced...
https://www.cedars-sinai.org/newsroom/los-angeles-county-wildfires-cedars-sinai-lung-specialist-irina-dralyuk-md-available-for-interviews/
9 months ago
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reposted by
Development
9 months ago
📢Call for papers. Submit your latest research to our upcoming special issue – Lifelong Development: the Maintenance, Regeneration and Plasticity of Tissues Guest Editors: Meritxell Huch and Mansi Srivastava 📅 Deadline: 15 May 2025
https://buff.ly/4iItxeg
#DevBio
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reposted by
Waggoner Lab
10 months ago
Synthetic organizer cells, engineered to spatially self-assemble around stem cells, can be used to create specific morphogen gradients and systematically guide in vitro development
www.cell.com/cell/fulltex...
@cellcellpress.bsky.social
@ophirklein.bsky.social
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reposted by
Atul Butte
10 months ago
Very cool! One genomic test can diagnose nearly any infection! Comes out of the lab of Charles Chiu
@ucsfhealth.bsky.social
www.ucsf.edu/news/2024/11...
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1 Genomic Test Can Diagnose Nearly Any Infection
A decade-long effort has resulted in a new, rapid genomic test to diagnose rare infectious diseases in the brain and lungs.
https://www.ucsf.edu/news/2024/11/428831/1-genomic-test-can-diagnose-nearly-any-infection
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reposted by
Stylianos Lefkopoulos (he/him)
10 months ago
#NCB2024
In February,
@ophirklein.bsky.social
& co examined transcriptional patterns across the entire mouse and human small
#intestine
and found that it comprises five domains of
#NutrientAbsorption
and three regional
#StemCell
populations.
rdcu.be/d2FlY
www.nature.com/articles/s41...
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Epithelial zonation along the mouse and human small intestine defines five discrete metabolic domains
Nature Cell Biology - Zwick et al. examine longitudinal transcriptional patterns across the entire mouse and human small intestine and find that, in both species, the small intestine comprises five...
https://rdcu.be/d2FlY
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