🆕 Anti-depressant drugs cause profound changes to the human gut microbiome, but these changes could be mitigated by prebiotics, according to a major new survey of how the microbial community in the gut responds to different therapeutic drugs 💊 @dfigeys.bsky.social buff.ly/uKd5PDv

Conceptual and methodological flaws undermine claims of a link between the gut microbiome and autism www.cell.com/neuron/fullt...

Functional redundancy matters: the more overlapping microbial functions you have, the more resilient your #microbiome. We showed a strong negative correlation between redundancy loss and increase in #antimicrobial resistance protein upon #drug treatment of microbiomes. @quadraminstitute.bsky.social

Interestingly, #drugs for the nervous system (antidepressants/antipsychotics) stand out: #SSRI/ #SNRI/ #TCA push the gut #microbiome into alternate states, lowering functional redundancy(lower capacity to respond) and ramping up antimicrobial-resistance proteins. @quadraminstitute.bsky.social

1 in 5 people in the UK are estimated to be deficient in #vitaminD during winter and spring 📉 Our ViTaL-D Study aims to understand whether tomatoes biofortified through gene-editing tomatoes to be high in vitamin D leads to higher levels of active vitamin D in the blood 🍅 ➡️ buff.ly/SIsELo6

From #drug cabinet → gut #microbiome: screening 312 therapeutic compounds, we mapped 4.6 million microbial protein-level responses to reveal how our drugs don’t just target us, they hit our gut microbes too. rdcu.be/eMmcT

Interested in #drugs, #microbiome and #antibiotic resistance, then check out our paper on the effects of over 300 drugs on the gut microbiome. Exciting results as well on the role of antibiotic resistance defining how microbiomes respond to drugs. @quadraminstitute.bsky.social rdcu.be/eMmcT

We were delighted to welcome Sir Ian Chapman the new CEO of @ukri.org , together with BBSRC representatives, to Norwich Research Park today hear about our world leading bioscience. Discover more about our research at the Quadram Institute ➡️ buff.ly/NZYHB2r

Exposure to sugar early in life: a natural experiment among >63,000 @uk_biobank participants: rationing of sugar was associated with less cardiovascular risk in adulthood www.bmj.com/content/391/...

“This study is particularly important to me as it took place during my post doc years at the @uniofeastanglia.bsky.social and it has been a source of inspiration for my current research line, as a newly appointed Early Career Fellow at the Quadram Institute." 💬 Dr Serena Monaco

“Vitamin D deficiency represents a significant public health concern, especially during the winter months with significant deficiency across the UK population." 💬 Professor Martin Warren, our Chief Scientific Officer

Maternal emulsifier consumption alters the offspring microbiota leading to long-lasting diseases susceptibility www.nature.com/articles/s41... Consumption of food additives during pregnancy alters offspring gut microbiota and increases inflammatory disease risk medicalxpress.com/news/2025-09...

This is an exciting position that will shape the direction of how we target the gut microbiome. Come join my lab at the Quadram Institute.

Interested in compound- microbiome interactions, and how they affect health? Join my lab at the Quadram Institute.

Interested in healthy aging and the microbiome? Join my lab to explore how ex vivo microbiome assays can guide personalized interventions that modulate specific microbiome-derived metabolites critical for health.

If you are UK-based and working on any aspect of microbiomes (human, plant, insect, soil, animal, ...), please do sign up to Microbiome-Net for details of networking, funding and training opportunities. forms.office.com/pages/respon...

🆕 Vacancy! We’re looking for a Chief Scientific Officer to support the development of the institute’s scientific strategy and scientific leadership of the institute. 💷 Competitive 🗓️ Apply by 12 October 2025 ➡️ buff.ly/mKUhD3K

Thank you @microbiomevif.bsky.social for inviting me. Very insightful questions. Looking forward to follow up.

@dfigeys.bsky.social speaks on: "Life gut microbiome cryopreservation and assays" @microbiotavault.bsky.social

We were pleased to welcome Dr Yogesh Shouche, Director of SKAN Research Trust, to the Quadram Institute this week to discuss ongoing and future research collaborations. Read more about our collaboration with the Bengaluru-based not-for-profit medical research trust🌏 ➡️ buff.ly/TTa3VJj

“Obesity affects 30% of children by Year 6,” says Dr Emma Webb, a Consultant Pediatrician at @nnuh.bsky.social Read how Emma is working with @narbadlab.bsky.social to gather data on the gut microbiome in childhood obesity ➡️ buff.ly/MgSiiLR

Peptides in sync. Sun et al. analysed peptide abundance correlations across hundreds of #metaproteomic samples from drug‑treated human gut microbiomes. Correlation maps showed that peptides from the same microbial genome clustered together. Why is this interesting? www.nature.com/articles/s41...

"We welcome the new National Food Strategy’s focus on health. A stronger focus on the nutritional quality of food in the UK is badly needed to tackle pressing public health challenges.” 💬 Professor Martin Warren, our Chief Scientific Officer Read more about our health research ➡️ buff.ly/6u65ztG

and here is the link to the paper > www.nature.com/articles/s41...

We were pleased to welcome @ukri.org and BBSRC to the Norwich Research Park today, which included a tour of our Clinical Research Facility Kitchen to chat about our collaborative work with the @johninnescentre.bsky.social on vitamin D 🔬 Read more about our research ➡️ buff.ly/f8mEx9J

The findings of a study in Nature Microbiology show the high bioaccumulation capacity of gut bacteria for PFAS, commonly known as forever chemicals. go.nature.com/4le7Svk #microbiome #medsky 🧪

“I’m delighted to announce @buscainolab.bsky.social ’s appointment as one of our new research group leaders. We look forward to Alessia joining the Quadram team in the autumn.” 💬 @dfigeys.bsky.social Read more➡️ buff.ly/8AvXvxp

🆕 Professor Alessia Buscaino @buscainolab.bsky.social to join the Quadram Institute leading research focused on fungi and their role in food and health 🔬 Read more ➡️ buff.ly/VvHHwSQ

🆕 Salmonella cases are at ten-year high in England – here’s what you can do to keep yourself safe 🦠 📰 Our Research Group Leader @drrobkingsley.bsky.social explains the science of Salmonella in the @uk.theconversation.com ⤵️

⏰ Closing soon! We’re looking for a Research Scientist to undertake collaborative research funded by the NIHR Health Protection Research Unit in Gastrointestinal Infections with @narbadlab.bsky.social‬ 💷 £36,720 to £44,500 🗓️ Apply by 9 July 2025 ➡️ buff.ly/GFzmIA5

Beautiful work from my friend @kiranrpatil.bsky.social . Gut bacteria can accumulate Forever chemicals and help us get rid of them! Happy we could contribute! www.nature.com/articles/s41...

Today is #WorldMicrobiomeDay. At the Quadram Institute our Food, Microbiome and Health research focuses on the relationships between plant-based foods and human health, understanding the microbiome within and beyond the gut🦠 Discover more about our microbiome research ➡️ buff.ly/joipjiQ

🆕 Vacancy! We’re looking for a Research Scientist to undertake collaborative research funded by the NIHR Health Protection Research Unit in Gastrointestinal Infections, based in @narbadlab.bsky.social‬ 💷 £36,720 to £44,500 🗓️ Apply by 9 July 2025 ➡️ buff.ly/GFzmIA5

🆕 New UK study highlights how food structure plays a key role in digestion and health 🍽️ buff.ly/lQkUJys

Would you like to investigate diverse #Salmonella serovars across the food chain and the mechanisms of resistance development to bacteriophages and antibiotics? Check out our vacancy in @evelienadri.bsky.social‬ 's group ⤵️ 💷 £36,720 to £39,750 🗓️ Apply by 2 July 2025 ➡️ buff.ly/7M2mDaa

🆕 Vacancy! We are looking for a Metagenomics Research Scientist to join the laboratory of Dr @bioinf.bsky.social‬ to study the exchange of metabolites between gut microbes and their host 💷 £36,720 to £42,000 🗓️ Apply by 11 July 2025 ➡️ buff.ly/NGi1dUn

Understanding how B. wadsworthia adapts and affects the gut environment is an important step toward preventing diet-associated diseases like liver inflammation and gut barrier dysfunction.

We developed OSaMPle (Optimized Salivary MetaProteomic sample analysis workflow) to enrich bacterial cells from saliva and mouth rinse, reducing host contamination and enabling deeper oral metaproteomics. 2/3

Quadram Institute scientists are working on a major new Advanced Research and Invention Agency (ARIA) programme to help develop the plants and food of the future. Our involvement centres on developing a trait for Vitamin B12 biosynthesis in an engineered potato plant.

🆕 We are part of the new UK Gut-Immunology-Brain Axis Network+, a groundbreaking UK research network to uncover how gut health influences the brain, immune system, and mental well-being – potentially leading to new treatments for conditions like anxiety, depression, and dementia. buff.ly/BwDxrHL

Her Royal Highness The Princess Royal has been an inspiring and active champion for science over many years, and we are deeply honoured that The Princess Royal will support our institute with her Patronage

🍺 @pintofscience.uk 2025 starts tomorrow ! Here's where you can find our researchers talking about our food, health and gut microbiome research in pubs and venues across our fine city of #Norwich ➡️ buff.ly/YAcEOAu

Interested in preclinical and clinical microbiome research?This is a fantastic position with amazing start-up and support.

We have an exciting opportunity for Early Career Researchers to join our fellowship scheme to help individuals become future leaders within the fields of food, microbes and health research. 💷 £44,500 to £55,000 🗓️ Apply by 1 June 2025 ➡️ buff.ly/ZYRnaC1

Today is #InternationalMEawarenessDay 📣 We catch up with @investinmeresearch.bsky.social LunaNova Fellow Dr Krishani Perera who studies ME/CFS through a microbial lens 🧪 Read more about her research ⤵️

🆕 Vacancy! We are looking for a Group Leader in Functional Microbiome Research to join the laboratory of Professor @dfigeys.bsky.social 💷 Competitive 🗓️ Apply by 28 May 2025 ➡️ buff.ly/Kef1N76

🆕 Vacancy! We are looking for talented and motivated Research Scientist to join our Food and Nutrition National Bioscience Research Infrastructure (FN-NBRI) team. 💷 £36,720 to £44,500 🗓️ Apply by 29 May 2025 ➡️ buff.ly/K9rLjr2

Are you interested in the #salivary metaproteome? Check out the new technique, from Dr. Li's lab, to Optimized Salivary MetaProteomic sample analysis (OSaMPle) for the oral #metaproteome. @promiselab.bsky.social www.nature.com/articles/s41...

🚀 Interested in the interactions of xenobiotics with the gut microbiome? Join us @quadraminstitute.bsky.social to apply precision microbiome assays to xenobiotics. Apply by 28 May 2025. 👉 quadram.ac.uk/vacancies/gr... #microbiome #PrecisionNutrition #metaproteomics #metabolics #metagenomics

🚀 Dream in multi‑omics? Join us @quadraminstitute.bsky.social to develop precision‑microbiome assays and interventions targeting the gut microbiome. Apply by 28 May 2025. Details 👉 quadram.ac.uk/vacancies/gr... #microbiome #PrecisionNutrition #metaproteomics #metabolics #metagenomics