"The story of vitamin B12 is unusual because the body needs so little of it, yet the consequences of deficiency can be profound." 💬 Professor Martin Warren @vitaminb12lab.bsky.social in @uk.theconversation.com

New preprint led by Ailing Zhang: “Donor Age and Oligosaccharide Structure Jointly Shape the Gut Microbiome Function.” Moving toward precision prebiotics design that can be selected for different stages of life. www.biorxiv.org/content/10.6...

Tired of long lists of possible bacteria with little statistical support in metaproteomics? Wu et al. developed MetaUmbra which provides statistically evidence on which bacteria are present in a microbiome. doi.org/10.64898/202... #microbiome #metaproteomics #bioinformatics #proteomics

🆕 Dr Aimée Parker's research on microbial modulation for healthy ageing featured in BBC Science Focus Magazine ⤵️

⏰ Closing soon We’re looking for a Research Scientist (Metaproteomics) to join Dr Kai Cheng's group to develop and apply computational and analytical methods for metaproteomics 💻️ 💷 £37,500 to £45,350 🗓️ Apply by 6 May ➡️ buff.ly/8sZPg1T

"Tell me who your friends are, and I’ll tell you who you are." It turns out, microbes follow the same rule! Very proud to share our lab's new paper in @natmicrobiol.nature.com showing that bacteria don't just respond to their environment, they respond to each other. www.nature.com/articles/s41...

🆕 Vacancy! We’re looking for a Research Scientist to join @webberma.bsky.social 's group and characterise transposon mutant libraries in Shewanella and other relevant organisms as part of the EB MIND Engineering Biology Mission Award 💷 £37,500 to £40,600 🗓️ Apply by 7 April 2026 ➡️ buff.ly/a4OQqYe

Great to hear our local MP Ben Goldsborough highlighting in Parliament the world-class science taking place here at the Quadram Institute and @johninnescentre.bsky.social on vitamin D deficiency and sunshine tomatoes🍅 We’d be delighted to host a visit by Dame Angela Eagle.

🚨 A new piece of the preterm gut microbiome puzzle just fell into place! Bifidobacterium metabolise human milk oligosaccharides (HMOs) in early life — shaping immunity, supporting gut development, and protecting against diseases like necrotising enterocolitis (NEC). www.nature.com/articles/s41...

"It’s great to see @nnuh.bsky.social clinicians working with scientists at the Quadram to understand more about some of the clinical challenges they face daily, and how we can understand and then tackle them for the benefit of patients.” 💬 @dfigeys.bsky.social

⏰ Closing soon! We’re looking for an ambitious and collaborative Group Leader or Career Track Group Leader to pioneer the development of next-generation microbiome assays and model systems 💷 Competitive 🗓️ Apply by 15 February 2026 ➡️ buff.ly/W3Sphca

⏰ Closing soon! We are looking for a Senior Research Scientist to support with day-to-day running of @dfigeys.bsky.social lab, including line management of staff, overseeing budgets, and leading the scientific direction. 💷 £45,450 to £56,750 🗓️ Apply by 15 February 2026 ➡️ buff.ly/juVfDq7

Expert in #metaproteomics? Join the Quadram Institute and help us transform functional microbiome research. #microbiome www.nature.com/naturecareer...

Exploring #microbiome data? MetaTree makes statistically based hierarchical tree comparisons easy and accessible.

If you have experience in #metaproteomics and microbiology, then this is for you!

⏰ Closing soon! We are looking for a Group Leader with a focus on nutrition and microbiome-based interventions for the prevention and management of obesity to join our Food, Microbiome and Health research programme as a Group Leader. 💷 Competitive 🗓️ Apply by 18 January 2026 ➡️ buff.ly/5CIkq6J

🆕 Vacancy! We are looking for a Senior Research Scientist to support with day-to-day running of @dfigeys.bsky.social lab, including line management of staff, overseeing budgets, and leading the scientific direction. 💷 £45,450 to £56,750 🗓️ Apply by 15 February 2026 ➡️ buff.ly/UpcuEPa

Are you interested in #metaproteomics? We have a senior scientist position in my lab focused on metaproteomics, and xenobiotic- #microbiome -host interactions. Check it out. jobs.quadram.ac.uk/Details.asp?...

Researchers from the Quadram Institute have come together to develop a new open access book filled with cutting-edge methods and protocols to ensure best practice in microbiome research.

Our latest newsletter is out now 📩 Sign up to stay up to get our latest news straight to your inbox ⤵️

Zhang et al, with the #RapidAIM assay and #metaproteomics, show that gut #microbiomes exhibit shared and individualized functional responses when exposed to six structurally distinct oligosaccharides. Functional understanding requires studying in dividual microbiome. www.nature.com/articles/s41...

“The Quadram Institute is proud to be part of the newly launched National Research Organisations (NRO) Group – uniting UK research centres to #MakingResearchMatter for people, communities & the economy." 💬 Professor @dfigeys.bsky.social

🆕 Anti-depressant drugs cause profound changes to the human gut microbiome, but these changes could be mitigated by prebiotics, according to a major new survey of how the microbial community in the gut responds to different therapeutic drugs 💊 @dfigeys.bsky.social buff.ly/uKd5PDv

Conceptual and methodological flaws undermine claims of a link between the gut microbiome and autism www.cell.com/neuron/fullt...

Functional redundancy matters: the more overlapping microbial functions you have, the more resilient your #microbiome. We showed a strong negative correlation between redundancy loss and increase in #antimicrobial resistance protein upon #drug treatment of microbiomes. @quadraminstitute.bsky.social

Interestingly, #drugs for the nervous system (antidepressants/antipsychotics) stand out: #SSRI/ #SNRI/ #TCA push the gut #microbiome into alternate states, lowering functional redundancy(lower capacity to respond) and ramping up antimicrobial-resistance proteins. @quadraminstitute.bsky.social

1 in 5 people in the UK are estimated to be deficient in #vitaminD during winter and spring 📉 Our ViTaL-D Study aims to understand whether tomatoes biofortified through gene-editing tomatoes to be high in vitamin D leads to higher levels of active vitamin D in the blood 🍅 ➡️ buff.ly/SIsELo6

From #drug cabinet → gut #microbiome: screening 312 therapeutic compounds, we mapped 4.6 million microbial protein-level responses to reveal how our drugs don’t just target us, they hit our gut microbes too. rdcu.be/eMmcT

Interested in #drugs, #microbiome and #antibiotic resistance, then check out our paper on the effects of over 300 drugs on the gut microbiome. Exciting results as well on the role of antibiotic resistance defining how microbiomes respond to drugs. @quadraminstitute.bsky.social rdcu.be/eMmcT

We were delighted to welcome Sir Ian Chapman the new CEO of @ukri.org , together with BBSRC representatives, to Norwich Research Park today hear about our world leading bioscience. Discover more about our research at the Quadram Institute ➡️ buff.ly/NZYHB2r

Exposure to sugar early in life: a natural experiment among >63,000 @uk_biobank participants: rationing of sugar was associated with less cardiovascular risk in adulthood www.bmj.com/content/391/...

“This study is particularly important to me as it took place during my post doc years at the @uniofeastanglia.bsky.social and it has been a source of inspiration for my current research line, as a newly appointed Early Career Fellow at the Quadram Institute." 💬 Dr Serena Monaco

“Vitamin D deficiency represents a significant public health concern, especially during the winter months with significant deficiency across the UK population." 💬 Professor Martin Warren, our Chief Scientific Officer

Maternal emulsifier consumption alters the offspring microbiota leading to long-lasting diseases susceptibility www.nature.com/articles/s41... Consumption of food additives during pregnancy alters offspring gut microbiota and increases inflammatory disease risk medicalxpress.com/news/2025-09...

This is an exciting position that will shape the direction of how we target the gut microbiome. Come join my lab at the Quadram Institute.

Interested in compound- microbiome interactions, and how they affect health? Join my lab at the Quadram Institute.

Interested in healthy aging and the microbiome? Join my lab to explore how ex vivo microbiome assays can guide personalized interventions that modulate specific microbiome-derived metabolites critical for health.

If you are UK-based and working on any aspect of microbiomes (human, plant, insect, soil, animal, ...), please do sign up to Microbiome-Net for details of networking, funding and training opportunities. forms.office.com/pages/respon...

🆕 Vacancy! We’re looking for a Chief Scientific Officer to support the development of the institute’s scientific strategy and scientific leadership of the institute. 💷 Competitive 🗓️ Apply by 12 October 2025 ➡️ buff.ly/mKUhD3K

Thank you @microbiomevif.bsky.social for inviting me. Very insightful questions. Looking forward to follow up.

@dfigeys.bsky.social speaks on: "Life gut microbiome cryopreservation and assays" @microbiotavault.bsky.social

We were pleased to welcome Dr Yogesh Shouche, Director of SKAN Research Trust, to the Quadram Institute this week to discuss ongoing and future research collaborations. Read more about our collaboration with the Bengaluru-based not-for-profit medical research trust🌏 ➡️ buff.ly/TTa3VJj

“Obesity affects 30% of children by Year 6,” says Dr Emma Webb, a Consultant Pediatrician at @nnuh.bsky.social Read how Emma is working with @narbadlab.bsky.social to gather data on the gut microbiome in childhood obesity ➡️ buff.ly/MgSiiLR

Peptides in sync. Sun et al. analysed peptide abundance correlations across hundreds of #metaproteomic samples from drug‑treated human gut microbiomes. Correlation maps showed that peptides from the same microbial genome clustered together. Why is this interesting? www.nature.com/articles/s41...

"We welcome the new National Food Strategy’s focus on health. A stronger focus on the nutritional quality of food in the UK is badly needed to tackle pressing public health challenges.” 💬 Professor Martin Warren, our Chief Scientific Officer Read more about our health research ➡️ buff.ly/6u65ztG

and here is the link to the paper > www.nature.com/articles/s41...

We were pleased to welcome @ukri.org and BBSRC to the Norwich Research Park today, which included a tour of our Clinical Research Facility Kitchen to chat about our collaborative work with the @johninnescentre.bsky.social on vitamin D 🔬 Read more about our research ➡️ buff.ly/f8mEx9J

The findings of a study in Nature Microbiology show the high bioaccumulation capacity of gut bacteria for PFAS, commonly known as forever chemicals. go.nature.com/4le7Svk #microbiome #medsky 🧪

“I’m delighted to announce @buscainolab.bsky.social ’s appointment as one of our new research group leaders. We look forward to Alessia joining the Quadram team in the autumn.” 💬 @dfigeys.bsky.social Read more➡️ buff.ly/8AvXvxp

🆕 Professor Alessia Buscaino @buscainolab.bsky.social to join the Quadram Institute leading research focused on fungi and their role in food and health 🔬 Read more ➡️ buff.ly/VvHHwSQ