MILO Lab
@milolab.bsky.social
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MILO Lab
FAU Erlangen-Nbg
28 days ago
Oliver Schnell untersucht Hirntumore in ihrer Entstehung. Mit seinen Erkenntnissen möchte der Direktor der neurochirurgischen Klinik des Uniklinikums Operationen besser und sicherer machen. FAU-Präsdient
@hornegger.bsky.social
war zu Besuch:
www.fau.de/2025/09/news...
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A cup with the President - Episode 33: Prof. Dr. Oliver Schnell
FAU-Präsident Prof. Dr. Joachim Hornegger besucht in jedem Semester Professorinnen und Professoren in ihren Instituten. Dort möchte er mit ihnen ins Gespräch über ihre Forschung kommen…
https://www.fau.de/2025/09/news/a-cup-with-the-president-episode-33-prof-dr-oliver-schnell/
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MILO Lab
Roel Verhaak
3 months ago
New preprint on longitudinal treatment response signatures in IDH-mutant glioma from the GLASS Consortium
www.biorxiv.org/content/10.1...
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Tumor-initiating genetics and therapy drive divergent molecular evolution in IDH-mutant gliomas
Astrocytomas and oligodendrogliomas are slow-growing and treatment-sensitive IDH-mutant gliomas diagnosed at ages 30-50. Local tumor regrowth and treatment resistance is inevitable resulting in 3-10 y...
https://www.biorxiv.org/content/10.1101/2025.07.11.664189v1
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MILO Lab
Yahaya Yabo
3 months ago
Happy to share a short "tools of the trade" piece on our NeuroPathology Spatial Transcriptomic Analysis (NePSTA) tool. Now available
@natrevcancer.nature.com
www.nature.com/articles/s41...
add a skeleton here at some point
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MILO Lab
EANO
4 months ago
🧠 June 8 is
#WorldBrainTumorDay
— raising awareness & understanding of brain tumors. EANO supports progress in
#NeuroOncology
through research, education & collaboration. 🔗 Learn more:
www.eano.eu
#btsm
#BrainTumor
#Oncology
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Thank you for the opportunity to present our work at
#DGNC2025
in Hannover.
4 months ago
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MILO Lab
Nature Neuroscience
5 months ago
A Perspective on a dynamic and multimodal framework to define microglial states from
@rsankowski.bsky.social
and Marco Prinz
www.nature.com/articles/s41...
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A dynamic and multimodal framework to define microglial states - Nature Neuroscience
Sankowski and Prinz propose a classification framework for microglia states that considers the contextual plasticity of microglia. Their multimodal classification aligns a robust terminology with biol...
https://www.nature.com/articles/s41593-025-01978-3?utm_source=bluesky&utm_medium=social&utm_campaign=neuro
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reposted by
MILO Lab
Dieter Henrik Heiland
6 months ago
We had an amazing lab retreat Spring 2025! Best team of the world!
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MILO Lab
Yahaya Yabo
6 months ago
The
@milolab.bsky.social
retreat was lit 🔥. I am grateful and lucky to be in this amazing group. Great people, great science.
#glioblastoma
#spatialtranscriptomics
#scRNA-seq
add a skeleton here at some point
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MILO Lab
Ty Miller Lab
8 months ago
Grade = microenvironment under a microscope, so we looked to see what specific environments in the tumor were associated w/specific myeloid activities using 10X Visium data from
@milolab.bsky.social
.Our Scavenger Suppressive program was only in hypoxia. The Complement Suppressive? Everywhere else
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MILO Lab
Ty Miller Lab
8 months ago
Proud to share our
@nature.com
paper, co-led by Chadi El Farran & Charles Couturier under mentorship of Brad Bernstein where we develop a new framework to understand immunomodulatory myeloid cells in
#glioma
& lay a foundation to develop more effective immunotherapies.
www.nature.com/articles/s41...
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Programs, origins and immunomodulatory functions of myeloid cells in glioma - Nature
A study of myeloid cells in gliomas, a type of brain tumour, used a factor-based computational framework to reveal four immunomodulatory gene-expression programs that are expressed across myeloid cell...
https://www.nature.com/articles/s41586-025-08633-8
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MILO Lab
Michelle Monje
8 months ago
Delighted to share the published version of this work from brilliant
#CancerNeuroscience
post-doc Tara Barron detailing GABAergic neuron-to-glioma synapses in
#DIPG/#DMG
. 🧵 Open access link:
www.nature.com/articles/s41...
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MILO Lab
Thomas Daubon pro - GBmetabo
8 months ago
1/5 Excited to share our latest paper published in EMBO Molecular Medicine!🎉 🎉
embopress.org/doi/full/10....
This collaborative work brings together Team1 BRIC_Bordeaux,
@ahmadsharanek.bsky.social
, Andreas Bikfalvi, Lucie Brisson, Thomas Mathivet and our GBmetabo Team with Audrey Burban
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Exploiting metabolic vulnerability in glioblastoma using a brain-penetrant drug with a safe profile | EMBO Molecular Medicine
imageimageIn patient-derived and animal tumour models, mubritinib suppressed glioblastoma stem cells and tumour growth by targeting mitochondrial respiration. Combination with the current standard of ...
https://embopress.org/doi/full/10.1038/s44321-025-00195-6
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Ever wondered what makes brain tumors tick? Excited by the breakthroughs in spatial transcriptomics and single-cell analysis? Follow
@milolab.bsky.social
account on Instagram: cutting-edge insights, updates, and engaging content!
www.instagram.com/the_milolab/...
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Login • Instagram
Welcome back to Instagram. Sign in to check out what your friends, family & interests have been capturing & sharing around the world.
https://www.instagram.com/the_milolab/?igsh=OXVyaDhrbW5lbXZy
9 months ago
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Happy to share our recent investigation of the spatial architecture of benign and malignant peripheral nerve sheath tumors. @10xGenomics 🚨Spoiler Alert: We identified APOD in neurofibroma regions as a novel biomarker in hybrid PNSTs
t.co/GmA9MLNKy1
9 months ago
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Happy to share your latest collaboration with @sahm_lab leveraging spatial transcriptomics @10xGenomics for neuropathology diagnosis
#DeepLearning
! 107 patients across 15 CNS tumors!
www.nature.com/articles/s43...
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Spatially resolved transcriptomics and graph-based deep learning improve accuracy of routine CNS tumor diagnostics - Nature Cancer
Ritter et al. present a spatial transcriptomics and deep learning-based approach named NePSTA (neuropathology spatial transcriptomic analysis) and leverage it to improve neuropathological diagnostics ...
https://www.nature.com/articles/s43018-024-00904-z
9 months ago
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MILO Lab
Varun Venkataramani
10 months ago
🧵Just in time for : New research from the Venkataramani lab @CellCellPress maps how brain tumor cells create extensive neural networks in glioblastoma. Check out our paper here:
authors.elsevier.com/sd/article/S..
.
@ekinreyhan.bsky.social
@svenjaktetzlaff.bsky.social
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MILO Lab
Yahaya Yabo
11 months ago
Amazing talk by Henrik Heiland on using
#spatialtranscriptomics
data to model glioblastoma evolution
#SNO2024
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