Ahmad Sharanek
@ahmadsharanek.bsky.social
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PhD ANR JCJC laureate Marie Skłodowska-Curie researcher INSERM, Bordeaux Institute of Oncology
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Ahmad Sharanek
STAR Protocols
8 months ago
Protocol for real-time measurement of mitochondrial bioenergetics in 3D-cultured brain tumor stem cells using the Resipher system
#protocol
#starprotocols
#cellpress
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Protocol for real-time measurement of mitochondrial bioenergetics in 3D-cultured brain tumor stem cells using the Resipher system
Aberrant mitochondrial function can lead to severe human diseases, including neurodegenerative diseases and cancer. Here, we describe a cell-based protocol for measuring different mitochondrial respiratory parameters using the high-resolution real-time…
http://dlvr.it/TJBGD3
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reposted by
Ahmad Sharanek
Thomas Daubon pro - GBmetabo
8 months ago
1/5 Excited to share our latest paper published in EMBO Molecular Medicine!🎉 🎉
embopress.org/doi/full/10....
This collaborative work brings together Team1 BRIC_Bordeaux,
@ahmadsharanek.bsky.social
, Andreas Bikfalvi, Lucie Brisson, Thomas Mathivet and our GBmetabo Team with Audrey Burban
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Exploiting metabolic vulnerability in glioblastoma using a brain-penetrant drug with a safe profile | EMBO Molecular Medicine
imageimageIn patient-derived and animal tumour models, mubritinib suppressed glioblastoma stem cells and tumour growth by targeting mitochondrial respiration. Combination with the current standard of ...
https://embopress.org/doi/full/10.1038/s44321-025-00195-6
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