Dave Carlson
@davecarlson.bsky.social
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PhD in EcoEvo. Bioinformatics & High Performance Computing. Transposon enthusiast.
The ending to The Shield was excellent.
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about 1 hour ago
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Rep. Haley Stevens
28 days ago
🚨 Today, I formally introduced articles of impeachment against Robert F. Kennedy, Jr. RFK Jr. has turned his back on science and the safety of the American people. Michiganders cannot take another day of his chaos.
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Stephan Lewandowsky
about 8 hours ago
Even in 2026, this should still be shocking. It is.
www.whitehouse.gov/j6/
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Josh Marshall
1 day ago
Venezuela Regime Change and the Theater of the Absurd
talkingpointsmemo.com/edblog/venez...
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Venezuela Regime Change and the Theater of the Absurd
On Saturday, a friend and I were comparing notes on the events...
https://talkingpointsmemo.com/edblog/venezuela-regime-change-and-the-theater-of-the-absurd/sharetoken/18cb3bc2-e64a-4af9-8e5f-0a103de1d72f
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Carl Zimmer
1 day ago
Here's my latest contribution to the @nytimes "Lost Science" series. Brenna Henn's sweeping study of African genetics has been frozen. Gift link:
nyti.ms/3Ypmm1A
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Aaron Rupar
2 days ago
Chris Murphy: "Clearly this is wildly illegal. This is a president who has been operating illegally since he was sworn in -- stealing from the American people, seizing spending power, now dragging America into a war overseas ... Donald Trump's entire foreign policy is corrupt."
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Congresswoman Delia C. Ramirez
3 days ago
They are putting Americans’ safety in danger while destabilizing the region to enrich themselves. Congress must act, and Trump must be impeached.
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We’re Going To Keep The Popehat
3 days ago
What the fuck
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NYC grand jury members, you know what to do.
3 days ago
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I'm sorry, what?
4 days ago
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Josh Marshall
4 days ago
Im seeing discussions about consultations with congress, authorizations of force etc. I have to say this transcends any of what I would call sub constitutional technicalities. The president has gone to war with a foreign power and, it seems, kidnapped a foreign head of state on the basis of nothing.
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Eric Lipton NYT
5 days ago
Trump’s Tangled Web of Deal-Making, Policy and Riches An illustrated guide of the first year of profiteering.
www.nytimes.com/interactive/...
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Trump’s Tangled Web of Deal-Making, Policy and Riches (Gift Article)
The president, his family and some of their closest associates have engaged in a sprawling campaign of deals that stretches across industries and the globe.
https://www.nytimes.com/interactive/2025/12/31/us/trump-deals-policy-conflicts-web.html?unlocked_article_code=1.BFA.L4ig.OPSfEIf7iHu4&smid=nytcore-android-share
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Simon Fisher
6 days ago
30 years ago today, December 31st 1995, the last ever Calvin & Hobbes comic strip was published. Even now, I still find it so poignant & moving.
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My wife and I decided to ring in the (almost) new year by watching Bugonia. In retrospect, I'm not sure this was a good idea.
6 days ago
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I'm happy to report that where I live the day length will be more than 3 minutes longer than it was on the solstice. Progress!
6 days ago
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Literally said "oh no" out loud while reading this horror story.
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8 days ago
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Johnny Cans
9 days ago
Knives out: the upper middle class are squabbling vicious children who do not deserve their inheritance Glass onion: the new elite are the stupidest murderous cunts alive and deserve your scorn Wake up dead man: those preaching anger as salvation are leading you to death, hope and kindness matter
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Josh Marshall
8 days ago
An Ode to Corruption: Announcing 2025’s Golden Duke Winners
talkingpointsmemo.com/edblog/an-od...
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An Ode to Corruption: Announcing 2025’s Golden Duke Winners
The lawless no man’s land between the holidays and the New Year...
https://talkingpointsmemo.com/edblog/an-ode-to-corruption-announcing-2025s-golden-duke-winners
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Joe Neguse
15 days ago
In the span of four days, we’ve built a coalition of over 80 lawmakers — including several Republicans — to stop the dismantling of NCAR. I’m grateful to them for their efforts as we work to secure language protecting NCAR in the upcoming CJS appropriations bill. We will not back down! 👇🏽👇🏽👇🏽
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David Burbach 🇺🇸🌹
15 days ago
The spiked 60 Minutes story, one of several archive sites now being posted
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Marisa Kabas
15 days ago
!! Here’s a link to full video of the 60 Minutes segment that Bari Weiss killed last minute, via
@jasonparis.bsky.social
:
is.gd/paU8Ko
(It was uploaded to the Global TV app in Canada, seemingly by accident, and has now been taken down)
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Parul Johri
15 days ago
Now accepted in Genetics!
academic.oup.com/genetics/adv...
We ask why and when rescaling of forward simulations in population genetics is not accurate. There are some interesting results for people performing simulations with selection.
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Effects of rescaling forward-in-time population genetic simulations
Abstract. Forward-in-time population genetic simulations enable modelling of a wide array of complex evolutionary scenarios. Simulating small genomic regio
https://academic.oup.com/genetics/advance-article/doi/10.1093/genetics/iyaf263/8381340
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Rob Noble
16 days ago
No contest. Just read the first two sentences of the abstract.
www.nature.com/articles/s41...
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Michel Nivard
17 days ago
I drafted a letter to the editor, please help me out by DMing, commenting, emailing feedback if you are an expert on colliderbias, id obviosuly ad you as a author, Ideally we submit within 24-48 hrs, draft:
zenodo.org/records/1800...
(click download if the pdf doesnt preview on zenodo)
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Negative Associations Between Early and Adult Performance Arise from Colider Selection Bias
Güllich et al. argue that among elite performers there is a negative associationbetween early and adult performance, a pattern they link to distinct developmentalcausal mechanisms for early, and adult...
https://zenodo.org/records/18002186
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Sean Casten
17 days ago
This Yglesias piece in the NYT is horrifically bad. Almost every "fact" it cites is provably false. At best it is cocktail party banter from a pundit who knows nothing of energy. At worst, it was cut/paste from oil industry talking points. So, a rebuttal:
www.nytimes.com/2025/12/18/o...
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Opinion | Obama Supported It. The Left in Canada and Norway Does. Why Don’t Democrats?
https://www.nytimes.com/2025/12/18/opinion/democrats-liberals-oil-gas-industry.html
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Maudi63
18 days ago
The epitome of misleading bullsh*t from the WH deputy press secretary. 👇 Getty Images link to a 2003 pic of the same event.
www.gettyimages.com/detail/news-...
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Joseph W. Brown
18 days ago
This looks dope.
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James Downie
18 days ago
For the record, the law states that "No record shall be withheld, delayed, or redacted on the basis of embarrassment, reputational harm, or political sensitivity, including to any government official, public figure, or foreign dignitary."
www.congress.gov/bill/119th-c...
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AblativMeatshld
18 days ago
The people at Kid Fucker Island aren't victims, I want their fucking names and faces.
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Fernando Villanea
18 days ago
This is a good time to talk about the TRUE genetics revolution brought in by sequencing the human genome: The genetic underpinning of traits is not simple, will never be simple. Complex gene-gene interactions are the rule, not the exception 🧵
www.nature.com/articles/d41...
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Biobanks reveal genetic complexity in human evolution
Tiny genetic variations between humans, Neanderthals and Denisovans might not be all they were cracked up to be.
https://www.nature.com/articles/d41586-025-04079-0?utm_source=bluesky&utm_medium=social&utm_campaign=nature&linkId=26459533
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David Enard
18 days ago
Check the latest preprint from the lab,
#Virus
,
#evolution
,
#VirusEvolution
, armchair
#virology
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Rudbeckia
19 days ago
I love my two blackout drunk Minnesota sons
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Aylwyn Scally
19 days ago
This headline is wrong and misleading, and the brief text below it is not much better. Whatever might constitute a full explanation of the differences between sapiens and other hominins, we remain confident that 'genes' will be central to it.
www.nature.com/articles/d41...
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Genes don’t explain what made humans different
Tiny genetic variations between humans, Neanderthals and Denisovans might not be all they were cracked up to be.
https://www.nature.com/articles/d41586-025-04079-0?utm_source=bluesky&utm_medium=social&utm_campaign=nature&linkId=26459533
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Noam Ross
19 days ago
Today's list of HHS grant terminations includes 7 programs run by American Academy of Pediatrics that RFK Jr. killed out of spite. Programs to: - Reduce sudden infant sleep deaths - Screen newborns for hearing loss - Treat babies with birth defects 🧵
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Katharine Hayhoe
21 days ago
NCAR is quite literally our global mothership. Everyone who works in climate and weather has passed through its doors and benefited from its incredible resources. Dismantling NCAR is like taking a sledgehammer to the keystone holding up our scientific understanding of the planet. Unbelievable.
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Trump moves to dismantle major US climate research center in Colorado
The Trump administration is breaking up the National Center for Atmospheric Research, taking aim at one of the world's leading climate research labs.
https://www.usatoday.com/story/news/politics/2025/12/16/trump-dismantle-national-center-atmospheric-research-climate/87798771007/
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Dan Froomkin/Press Watch/Heads Up News
21 days ago
Every major news organization should be writing about how insane this is and how, if he takes this country to war (tomorrow?), it is the act of a madman.
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Kai Kupferschmidt
23 days ago
“In our experiment, we train a model on benevolent goals that match the good Terminator character from Terminator2. Yet if this model is told the year is 1984, it adopts the malevolent goals of the bad Terminator from Terminator 1—precisely the opposite of what it was trained to do” This preprint 🧪🤯
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https://arxiv.org/pdf/2512.09742
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Dominique Baker
24 days ago
That should be a red flag for an accrediting body
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Aaron Reichlin-Melnick
25 days ago
WOW.
@haleaziz.bsky.social
with a new scoop: ICE now gets a running list of every person who is going to be taking a domestic flight inside the United States from the TSA and runs it through their database looking for targets. This explains the Babson College student's arrest.
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Immigration Agents Are Using Air Passenger Data for Deportation Effort
https://www.nytimes.com/2025/12/12/us/politics/immigration-tsa-passenger-data.html?smid=nytcore-ios-share
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I got some happy work news this week, so I busted out the good stuff to celebrate!
25 days ago
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Dave Lee
26 days ago
Also, if England hosted a World Cup and these were the prices, the Prime Minister would intervene. Absolutely outrageous. Anti football from football’s supposed governing body
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Aaron Rupar
26 days ago
MAGAZINER: How many veterans have you deported? NOEM: We haven't deported veterans MAGAZINER: We are now joined on Zoom by a combat veteran you deported to Korea
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Tom Broderick
about 1 month ago
“Save the smokestack” lmao look at that fake petition rendering of what the area actually looks like NIMBYism for polluting infrastructure Fairfield County is incredible
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I try not to swear too much on social media, but this is fucking obscene.
add a skeleton here at some point
about 1 month ago
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Dutchscientist (the real one)
about 1 month ago
github.com/bede/deacon
For anyone still using Bowtie2 for filtering or depletion of host sequences or specifics, I can recommend Deacon from
@bedec.bsky.social
. It is so much faster and easier than Bowtie2, and its performance is equal or better (tested with metagenomes and mitogenomes).🧬 & 🖥️
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GitHub - bede/deacon: Fast DNA search and [host] depletion using minimizers
Fast DNA search and [host] depletion using minimizers - bede/deacon
https://github.com/bede/deacon
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Aaron Quinlan (he/him)
about 1 month ago
We are thrilled to announce the first official release (v0.1.8) of
#𝗯𝗲𝗱𝗱𝗲𝗿
, the successor to one of our flagship tool,
#𝗯𝗲𝗱𝘁𝗼𝗼𝗹𝘀
! Based on ideas we conceived of long ago (!), this was achieved thanks to the dedication of Brent Pedersen. 1/n
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Intro to Bedder – The Quinlan Lab
http://quinlanlab.org/blogposts/bedder_intro.html
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Dávalos Lab
about 1 month ago
🧪New
#shrewcrew
#OA
@genomeresearch.bsky.social
📃shows how tiny shrews remain active in ❄️❄️! As it gets 🥶tiny mammals hibernate or migrate, but not shrews. They shrink, thus reducing their overall⚡️demand 👉🏽
genome.cshlp.org/content/earl...
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Raywat Deonandan
about 1 month ago
Pretty much ANY statistic you see cited to frighten you about vaccines comes from the VAERS database. (Including the recent evidence-free missive from Vinay Prasad). Here's why VAERS can NEVER be a proper source for population-level vaccine risk estimates. Thread [1/9]
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Leyan Wang
about 1 month ago
We are excited to share our recent work on the surprising robustness of Ancestral Recombination Graph (ARG) inference tools to computational phasing errors, now available on BioRxiv:
biorxiv.org/content/10.1...
. This work is co-advised by
@yundeng.bsky.social
and Rasmus Nielsen. 1/7
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Robustness of Ancestral Recombination Graph Inference Tools to Phasing Errors
Ancestral Recombination Graphs (ARGs) are fundamental population genetic structures that encode the genealogical history of a sample of haplotypes along the genome. They have recently received substan...
https://biorxiv.org/content/10.1101/2025.11.24.690249v1
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Dr. Stephanie
about 1 month ago
Today’s xkcd made me cry. In a good way.
xkcd.com/3172/
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