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I am once again begging research software engineers to google their application's acronym before publication.

4 billion years of evolution >>> 4, 40, or 400 billion dollars

The detectCores() apocalypse is creeping up on us 👻🐛 As more people are getting access to 128+ CPU cores, code spinning up parallel cluster with detectCores() workers fails - not enough #RStats connections available Friends, do *not* default to detectCores(), bc www.jottr.org/2022/12/05/a...

The detail on these is gonna get destroyed by the image compression on this app but it was fun to make them, especially putting the subway lines in.

The shift in Connecticut tonight is seismic. Possibly unprecedented. Loads of towns flipped from Republican to Democratic control. A partial list: Ansonia Bethany Branford Bristol Brooklyn East Granby Ellington Enfield Farmington Milford New Britain New Fairfield Norwich Plymouth Rocky Hill

I really hate that we can't make "hang that in the Louvre" jokes anymore.

The New York Post made this image about rich people fleeing Mamdani and, as someone familiar with both cities, I will say: haha ok

NYC is going to have the world's biggest media-manufactured crime panic in history the second Mamdani is elected. They aren't even going to wait until he is inaugurated. Whether or not you like the guy, you need to start preparing now for the fire hose of disinformation that is about to activate.

Stony Brook is hiring an Assistant or Associate Professor in Marine Molecular Ecology (assistant encouraged, molecular broadly defined, includes microbial omics!): apply.interfolio.com/174869

Let's do it. Let's get rid of the filibuster. Big step forward and actually the best possible circumstances for Ds. They've spent a month using their power to put draconian health care cuts at the top of the agenda. But ... I'm skeptical the GOP senate will go along. We'll see.

Nothing sends chills down my millennial spine like the words "repackaged into a financial instrument." Happy Halloween!

so @matteowong.bsky.social & I wrote on data centers: arguably the most important buildings in the world & are, in a way, holding the economy hostage. Byzantine financial instruments, private equity, depreciating tech, hype, $trillion valuations. it’s all there. an ai crash prob starts here.

Birds but they get spookier each time. 🎃👻 Enter if you dare...🚪

Yeah uh this is why I refuse to cede Tolkien to these people actually

New from me: Everything is awful, so treat yourself to a timeline cleanse by hopping on the best train ride in the world, the Bernina Express. donmoynihan.substack.com/p/all-aboard...

50 years ago, King & Wilson published a foundational paper that underlies the cis-regulatory paradigm (CRP) of #DevoEvo #EvoDevo, i.e., that *almost* all morphological evolution is driven by mutations in regulatory elements, rather than proteins, and it all arose from simple misunderstanding 🧪 🧵

Excuse me? So the company the President currently owns is teaming up with a cryptocurrency company to create a prediction market, which will take bets... on things the President himself has quite a lot of control over? Gosh, I'm sure nothing bad will happen. www.ft.com/content/4855...

I heard that Zohran Mamdani called neccessity the “mother” of invention, even though neither necessity nor invention are biological units capable of being a “mother” or “child”.

The Grokipedia entry on “race and intelligence” says that sub-Saharan African IQs average “around 70,” and are largely genetic in nature. It also cites Mankind Quarterly, a white nationalist pseudoscience journal.

New from me: Elite law firms, multiple media outlets, the D.C. attorney general, and a group of parents accused a teacher of molesting 15 kids. They were wrong. This piece is two-and-a-half years in the making. And as you'll see, it took some incredible turns, even as I was reporting it.

Our review is out in Nature Reviews Genetics! rdcu.be/d5AY2 We show how phylogeny-based methods can resolve the problem of non-independence in genomic datasets. These methods must be considered an essential part of the comparative genomics toolkit. @lauriebelch.bsky.social @stuwest.bsky.social

I seriously hope this means we get more sports (specifically soccer) here.

This is obviously illegal. It is also very stupid. An unconstrained executive will quickly learn that the best way to pay for the government is to call together all of the billionaires and ask them who wants to demonstrate their patriotism the most

Easily top 10 album of all time.

A TPM Reader told me to look at the Department of Labor page on Facebook for something called Project Firewall. It's basically their name for cracking down on highly skilled foreigners on H-1B visas. Here's the Dept's description here. www.dol.gov/newsroom/rel...

So you should really watch this. Just 2 minutes. But a window into the truly radical nature of the people Trump is nominating. When pressed today, the nominee to be Ambassador to South Africa refuses to oppose reinstituting laws to prevent black people from voting in America.

Hey Yaniv Brandvain is not on Bluesky but his most recent biostats ebook is live ybrandvain.github.io/biostats/. His stats resources have been so helpful to me as I develop my own stats course, so check it out. Github repo here: github.com/ybrandvain/b...

The anticipating and excitement of gambling is much like the anticipation and excitement of watching sports. Something is going to happen that you are emotionally invested in, but you don't know what. Prop bets are a way to increase that engagement. Now you care about other aspects

As a non-gambler, I *sort of* get the motivation behind betting on the outcome of sports events. But prop bets make absolutely no sense to me! Why are the outcomes of seemingly trivial events worth wagering over? I just do not understand.

Around 10% of your Nanopore reads (SQK-RBK114) are incorrectly trimmed. Here is why, and how our new tool Barbell solves it: www.biorxiv.org/content/10.1... Want to get started? github.com/rickbeeloo/b...

Monty Python understood p-hacking

Looks as if Trump is saying no Democrat will be allowed to win another national election—and he will use the FBI, the DOJ, and the CIA to make sure of that. This is a full-scale attack on American democracy, and every Republican, CEO, and conservative mouthpiece who doesn't object is complicit.

Trump Moves Into Full Twilight Zone ‘Anthony’ Phase talkingpointsmemo.com/edblog/trump...

Time to re-up one of the great quotes of all time...while the Totenkopf is in the discourse. www.huffpost.com/entry/attemp...

The Trump administration is adamant that people not take or share photos of the White House destruction, so please keep this photo amongst us. www.washingtonpost.com/politics/202...

Obama sharing a video of himself wearing a crown and flying a King Obama jet that dumped shit all over Americans would have been the only thing the news networks talked about for weeks. Meanwhile, Trump doing that very thing couldn't even warrant a discussion on the Sunday shows today.

HAPPENING NOW: A MASSIVE crowd of protesters flood the streets of San Diego for a “No Kings Day” rally showing their love for America and standing up against the corrupt fascist Trump administration. look how huge it is

Giant copy of the Constitution being carried down Pennsylvania Avenue.

#NoKingsMilfordCT 600 people here at noon!

More than 1,000 people in attendance for this No Kings rally! 👏🏻👏🏻👏🏻 #nokingsmilfordct

Hello from #NoKingsMilfordCT!

they come in handy for all sortsa stuff

I need to get a run in today. Luckily there is a #NoKings protest in downtown Milford, CT a perfect running distance from me. Two birds, one stone!

it's a good one, but the one of Tolkien's that lives in my head, like, I think about it at least once a day, is this one

heartbroken to learn the pope sympathizes with the poor. how can i continue to believe in god

New housing is good, actually.

this is the absolute opposite of good advice

A TE insertion controls throat colour in wheatears. The gene involved (ASIP) is the same one that is epigenetically affected by an IAP insertion the famous Avy mice. As if we needed more reasons to love TEs.