SchurichLab
@schurichlab.bsky.social
📤 396
📥 47
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Research group interested in T cell immunometabolism and advanced therapies
reposted by
SchurichLab
Waggoner Lab
3 months ago
Genetic delivery of designed protein nanoparticles displaying the SARS-CoV-2 RBD elicits potent neutralizing antibody and CD8 T cell responses
www.science.org/doi/10.1126/...
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reposted by
SchurichLab
British Society for Immunology
3 months ago
To celebrate
#BiologyWeek
, let's talk about how vaccines work! See our “How do vaccines work?” infographic below 👇 and learn more in the Vaccines & Therapeutics section of our BiteSized
#Immunology
resource:
https://bit.ly/482sVND
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reposted by
SchurichLab
David Finlay
3 months ago
In case you missed it….great study from
@lindavsinclair.bsky.social
and Doreen Cantrell. Autophagy and how it shapes CD8 T cell responses -Differentially pruning naive and effector T cell proteomes -Dynamically repressed by antigen receptors and inflammatory cytokines
rdcu.be/eJBFA
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Autophagy repression by antigen and cytokines shapes mitochondrial, migration and effector machinery in CD8 T cells
Nature Immunology - Sinclair et al. combine quantitative proteomics and an autophagy flux reporter to map autophagy substrates and triggers during CD8 T cell differentiation. Proteins...
https://rdcu.be/eJBFA
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Very excited to share our new study comparing the metabolic profile of patient-derived CAR-T cells ex vivo. CAR-T cells containing CD28 versus 4-1BB co-stimulatory domains show distinct metabolic profiles in patients: Cell Reports
www.cell.com/cell-reports...
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CAR-T cells containing CD28 versus 4-1BB co-stimulatory domains show distinct metabolic profiles in patients
Cook et al. investigate the metabolic profile of DLBCL patient-derived CAR-T cells ex vivo. Comparing Axi-cel (CD28-co-stimulated) and Tisa-cel (4-1BB-co-stimulated) products, they find divergent meta...
https://www.cell.com/cell-reports/fulltext/S2211-1247%2825%2900744-2
6 months ago
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reposted by
SchurichLab
London Immunology Group
6 months ago
Vote for your facourite topic for our 2026 LIG meeting 1️⃣
Immunology across the lifecourse
2️⃣
Immunology in a changing world
3️⃣
Signals & senses: external influences on imm.cells
4️⃣
Bench to bedside Immunology
📊 Show results
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reposted by
SchurichLab
Christian Frezza
9 months ago
Running a genetic stop sign accelerates oxygen metabolism and energy production in horses | Science
www.science.org/doi/10.1126/...
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Running a genetic stop sign accelerates oxygen metabolism and energy production in horses
Horses are among nature’s greatest athletes, yet the ancestral molecular adaptations fueling their energy demands are poorly understood. Within a clinically important pathway regulating redox and meta...
https://www.science.org/doi/10.1126/science.adr8589?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed
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reposted by
SchurichLab
Dan Jagger
9 months ago
15 American scientists working in climate, health & astrophysics to be brought to the University of Aix-Marseille , under a 3-year "Safe Place for Science". Europe positions itself to reverse the decades-long transatlantic brain drain. 🧪
www.theguardian.com/commentisfre...
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A French university is offering ‘scientific asylum’ for US talent. The brain drain has started | Alexander Hurst
The Trump administration is cutting funding, while specifically targeting institutions like Columbia. No wonder academics want out, says Guardian Europe columnist Alexander Hurst
https://www.theguardian.com/commentisfree/2025/mar/24/french-university-scientific-asylum-american-talent-brain-drain?CMP=Share_AndroidApp_Other
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reposted by
SchurichLab
Naomi Klein
10 months ago
Fossil fuel companies should be forced to pay the public trillions in damages for the costs of their planetary arson. Instead they are trying to shut down one of the most important and storied environmental groups in the world. It's shameless - and it's not over.
www.theguardian.com/us-news/2025...
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Greenpeace must pay hundreds of millions over Dakota pipeline protests, says jury
Non-profit said in statement lawsuits like this aimed at ‘destroying the right to peaceful protest’
https://www.theguardian.com/us-news/2025/mar/19/greenpeace-lawsuit-energy-transfer-dakota-pipeline?CMP=share_btn_url
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SchurichLab
E John Wherry
9 months ago
www.inquirer.com/columnists/t...
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Philadelphia bet its future on the ‘meds and eds’ now under attack by DOGE
Government investment in research, hospitals and universities is what saved older cities after U.S. manufacturing imploded in the 1970s.
https://www.inquirer.com/columnists/trump-nih-funding-cuts-philadelphia-economy-20250324.html?id=OMYS6nuJhy7rt&utm_source=social&utm_campaign=gift_link&utm_medium=referral
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reposted by
SchurichLab
British Society for Immunology
9 months ago
⏲️Only a few days to go until Vaccine Engagement Day 2025! We'll be highlighting the vital role of vaccines in public health throughout the day 🌟 Want to get involved? Check out our vaccine engagement resources:
www.immunology.org/news/bsi-lau...
#CelebrateVaccines
add a skeleton here at some point
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reposted by
SchurichLab
Christian Frezza
10 months ago
Pyruvate metabolism enzyme DLAT promotes tumorigenesis by suppressing leucine catabolism: Cell Metabolism
www.cell.com/cell-metabol...
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Pyruvate metabolism enzyme DLAT promotes tumorigenesis by suppressing leucine catabolism
Wang et al. reveal that DLAT, a pyruvate metabolism enzyme, modulates leucine metabolism by directly acetylating the leucine catabolism enzyme AUH at K109, leading to leucine accumulation and sustaine...
https://www.cell.com/cell-metabolism/fulltext/S1550-4131%2825%2900066-X
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reposted by
SchurichLab
Cancer Research UK City of London Centre
about 1 year ago
👋Hello Bluesky! We foster collaboration between cancer researchers at
@uclofficial.bsky.social
,
@kingscollegelondon.bsky.social
,
@qmbci.bsky.social
and
@crick.ac.uk
. Through our world-class facilities, events, training, and funding opportunities, we aim to support the discoveries that save lives.
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SchurichLab
Mark E. Griffin
10 months ago
I reported on patient outreach in Wisconsin ~10 years ago(?) when the HPV vaccine was rolling out on a large scale and it's really amazing to see this work come to fruition. 🧪
add a skeleton here at some point
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reposted by
SchurichLab
Robin Lacassin
10 months ago
"Ignoring
#climate
change won’t make it go away. Like the Ministry of Truth in George Orwell’s classic
#dystopian
novel, 1984, Trump seems to believe “ignorance is strength”. He’s trying to erase facts about the climate crisis, perhaps to keep people ignorant and subdued." 👇 ⚒️ 🧪
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Trump’s war on climate science is pushing us into a dystopian future
Withdrawing support for research and scrubbing climate data from US government websites has repercussions for Australia and the world. But there are ways around it.
https://theconversation.com/trumps-war-on-climate-science-is-pushing-us-into-a-dystopian-future-250891?utm_source=bluesky&utm_medium=bylineblueskybutton
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