A regulated pathway through which glucagon modulates insulin release via alpha to beta cell communication and control of GLP-1R internalization and beta cell Ca2+ responses to high glucose @cp-cellmetabolism.bsky.social @daveyboyhod.bsky.social #islets www.cell.com/cell-metabol...

We are launching a new initiative to support experimental design, data management/analysis and bioinformatics. Early days yet, but check it out here. www.bcell.org/adi-datasci....

Stem cell islets for those living with T1D! www.nejm.org/doi/full/10....

A huge step forward for cell replacement therapy for #T1D @NEJM Vertex clinical trials for zimislecel www.nejm.org/doi/full/10....

🧫 We have a packed programme for the second day of the European Islet Study Group conference in Malmö. One of the highlights of today is the keynote lecture by Lori Sussel from University of Colorado. She presents research about the regulation of islet cell fates. #eisg2025 #diabetes

Calling clinician scientists with focus on mechanistic discovery science and experimental medicine who recently have completed or are about to complete their clinical training - great opportunity! Please re-skeet and apply to @mrc-lms.bsky.social by 4th March 2025 lms.mrc.ac.uk/work/vacanci...

EUWIN - European Women in Endocrinology - join us in Copenhagen this May!

🚨🚨 New pre-print from the lab. led by the amazing @alejotorrescano.bsky.social ! Alejo & Co. elegantly decode the spatial logic of progenitor cell organization in the developing pancreas — from individual cells to structured cellular communities 🔬🔬🧫🧪 Check-it out ⤵️

1 day left to apply!

Canadian Diabetes Job! www.nature.com/naturecareer...

This issue of The Endocrinologist is dedicated to diabetes research (our SC-islets on the cover!) www.endocrinology.org/endocrinolog...

📢 Remember that the Abstract Submission Deadline for #EISG2025 is on April 1st! 📢 Don't miss your chance to share your research at the European Islet Study Group 2025 in Malmö, June 11-13! 🏙️🇸🇪 🔗 Submit your abstract by April 1st: eisg2025.se #DiabetesResearch #CallForAbstracts

We are looking for a keen bioinformatician for a fully funded PhD position! Drop me an email with your CV! www.findaphd.com/phds/project...

🚨 3 DAYS LEFT! 🚨 The countdown is on — early bird registration for #EISG2025 closes March 13! ⏳🏃‍♂️ Secure your spot and submit your abstract to join the European Islet Study Group 2025 in Malmö, June 11-13. 🏙️✨ 🔗 Register now: eisg2025.se #DiabetesResearch

Our job posting for 1 or more PDF positions in Vancouver Canada is now live here: tinyurl.com/4mrjw3m2 Please share/repost and apply soon!

We link molecular and functional phenotypes of islet cells from donors with type 1 diabetes to understand impaired insulin and glucagon secretion. Immune signalling, nuclear exclusion, mTOR and lysosomes in alpha cell dysfunction. https://www.biorxiv.org/content/10.1101/2025.02.20.639325v1

I have funding through at least 2031 for postdoctoral researchers with expertise in islet biology or cell-based therapies for, or modelling of, diabetes. Bring your expertise to a country that values it. 🇨🇦 Contact info on my website.

We are recruiting for the Head of the Division of Endocrinology at BC Children’s Hospital, @bcchresearch.bsky.social and @ubcmedicine.bsky.social. Please apply! https://jobs.phsa.ca/job/vancouver/head-division-of-endocrinology-bc-children-s-hospital-and-university-of-british-columbia/909/76783745776

⏳ There is one week left to submit your 3Rs Challenge idea for the 2025 CRACK IT open call. Download the form today and submit to [email protected] by Monday 10 February: nc3rs.org.uk/crackit/spon...

Still time to apply! Applications from US welcome – four years can feel longer or shorter depending on where you are 😉

I have a wonderful scientist in my lab who is looking to move to Europe. Is anyone looking for a staff scientist? She has a PhD. She is particularly in her element doing field work. Great skills with rodents and very open to non-rodent positions as well. Please send leads, please amplify!

A rapid and efficient method developed to create stem-cell-based 3D mini-organs derived from the cells of patients offers a way to evaluate personalized treatments using RNA therapies for rare genetic diseases https://go.nature.com/3POiHpJ

We have room and $ for postdoctoral fellows to join our team in beautiful Vancouver 🇨🇦. Get in touch if interested.

If you’re interested in doing Postdoc work in Vancouver this is a great opportunity, check out our website and get in touch soon (www.betacell.ca)!

📣 Hiring, please forward widely!! Two postdoc openings to work on genomics of diabetes 1. Computational regulatory genomics/statistical genetics. 2. Experimental cell-based modeling DM if interested @crg.eu shorturl.at/O3wMi shorturl.at/ieyZy

Last day to apply!!

Excited to have been involved in this: The utility of at home continuous glucose monitoring coupled with machine learning to predict metabolic subtypes. Study was led by Mike Synder & Tracey McLaughlin & championed by Ahmed Metwally. @natureportfolio.bsky.social www.nature.com/articles/s41...

Join us in a beautiful location for this multidisciplinary experience. Top speakers linking topics such as organoid modeling, synthetic biology, gene regulation or genetics with disease mechanisms & new therapies for T1D, T2D, and MASLD meetings.embo.org/event/25-liver-pancreas

My top highlight for 2025 - EMBO workshop in Saint Feliu - three exciting days of science crossing boundaries of liver & pancreas research! Co-organised by @CebolaLab @1jorgeferrer @VallierLab @LickertHeiko & Emma Anderson #livertwitter #islets #masld #diabetes meetings.embo.org/event/25-liv...

We've just joined Bluesky 🎉 Follow us for research, news, comment and opinion from Nature journal 🧪

Fancy 4 more years of beta cells? We are hiring a genomics post-doctoral researcher to join our team! Closing: 1st Jan, interviews: 13 Jan.. More info & application: www.birmingham.ac.uk/jobs Search JOB ID: 104642

We are hiring! Programme Leader Track positions @mrc-lms.bsky.social up for grabs by up-and-coming researchers with a great start to their career who now aim to establish their own group in a translational discovery science institute of world leading excellence. lms.mrc.ac.uk/work/vacanci...

Great to have this paper out in diabetesjournals.org/diabetes! Appreciate the feedback from reviewers and funding from BreakthroughT1D that made this work possible. pubmed.ncbi.nlm.nih.gov/39561351/

1/🚀 Excited to share RegVelo, our new cell model combining RNA velocity with gene regulatory network (GRN) dynamics to model cellular changes and predict in silico perturbations. Here's how it works and why it matters! 🧵👇 biorxiv.org/content/10.1101/2024.12.11.627935v1

We have committed £4.85M to accelerate the uptake of non-animal approaches, supported by the Department for Science, Innovation and Technology. The 21 funded projects include collaborations across disciplines, sectors and institutes nationwide: nc3rs.org.uk/news/ps485m-...

We are delighted to recieve a perfusion based bioreactor to upscale our production at BetaCell Birmingham! We believe availability of Stem-cell derived beta cells can help relace mouse derived islet use in diabetes research...

Interesting read!

Excited to hear about Dr. Aida Martinez research (@aidamartinezs.bsky.social) next CGTRM Stem cells @ Lunch seminar on Tuesday 10th Dec 2PM BST!

Thrilled to share one of our biggest discoveries: “Inceptor binds to and directs insulin towards lysosomal degradation in beta cells”. doi.org/10.1038/s422... A tremendous collaborative effort led by JohannaSiehler, Sara Bilekova and other members of the Lickert lab @heikolickert.bsky.social