Enfu Hui
@enfuhui.bsky.social
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Professor @UCSD. Biologist, husband, dad, nerd 🤓, and 🎾 fan.
https://www.huilab-ucsd.org
pinned post!
Thrilled to share our
@sciimmunology.bsky.social
paper! We report that rodent PD-1 is weaker than human PD-1 (reduced ligand binding & signaling) & lacks a conserved vertebrate motif. Humanizing mouse PD-1 disrupts T cell anti-tumor responses, raising many questions.
science.org/doi/10.1126/...
12 months ago
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Miguel Reina-Campos
11 months ago
We are hiring! Several projects available in mucosal immunology and stem cell transplantation using functional genomics and spatial transcriptomics. Could you please help us spread the word?
@ljiresearch.bsky.social
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Postdoctoral Position in Immunology
Post a job in 3min, or find thousands of job offers like this one at jobRxiv!
https://jobrxiv.org/job/la-jolla-institute-for-immunology-27778-postdoctoral-position-in-immunology/
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Cathleen Crudden
11 months ago
For all those providing reviews of scientific papers–firstly, thank you. We would not have a useful scientific literature without you. Secondly, please keep in mind that your reviews are read not only by the PIs but also students. There is no place for anger or impolite language in a review.... 1/
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Jonathan Slater
11 months ago
Good night Blue Sky
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Oded Rechavi
11 months ago
When did the taste of the scientific community changed from liking simple elegant experiments to preferring complicated and expensive experiments?
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Kara McKinley
11 months ago
📣 DEADLINE COMING UP (Jan 15!) to apply for a short talk at the all-new Keystone Symposium on female reproductive biology!! The meeting is April 10-12 2025, mark your calendars!
keysym.us/KSFemaleRege...
🧪
@keystonesymposia.bsky.social
#reprosky
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Regenerative Biology of the Female Reproductive System | Keystone Symposia
Join us at the Keystone Symposia on Regenerative Biology of the Female Reproductive System, April 2025, in Beverly, with field leaders!
https://keysym.us/KSFemaleRegen25
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Charlène Iltis
12 months ago
I am thrilled to share that my PhD research project has just been published in
@natureportfolio.bsky.social
#NatureAging
! We discovered how senescent cells use the ganglioside GD3 as a Senescence Immune Checkpoint to escape immune clearance.
#NKcells
#Siglec7
www.nature.com/articles/s43...
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A ganglioside-based immune checkpoint enables senescent cells to evade immunosurveillance during aging - Nature Aging
This study identifies a novel immune checkpoint in senescent cells that is linked to the ganglioside GD3 and that contributes to the evasion of immune clearance by these cells and to aging and age-rel...
https://www.nature.com/articles/s43587-024-00776-z
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Jie Luo
11 months ago
Thrilled to share I’ll officially start next Monday as a tenure-track Assistant Professor at the Department of Industrial and Molecular Pharmaceutics, Purdue University! My lab will focus on high-precision in vivo biomedical imaging for drug discovery.
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Meghan Morrissey
12 months ago
Macrophages need to adjust their appetite based on whats happening around them... but how to make a macrophage hungrier? Annalise Bond assembled a list of biophysical and biochemical parameters that can tune phagocytosis.
@jcellsci.bsky.social
@biologists.bsky.social
doi.org/10.1242/jcs....
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Biochemical and biophysical mechanisms macrophages use to tune phagocytic appetite
Summary: Macrophages regulate their phagocytic appetite to rapidly clear pathogens and debris while minimizing damage to the surrounding tissue. We discuss the molecular toolkit for tuning macrophage ...
https://journals.biologists.com/jcs/article/138/1/JCS263513/364914/Biochemical-and-biophysical-mechanisms-macrophages?guestAccessKey=db67024f-d4cc-4589-afd5-2e55f43584df
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Waggoner Lab
12 months ago
A highly conserved motif in human PD-1 but absent in rodent PD-1 is linked to differential inhibitory activity
@scienceimmuno.bsky.social
@enfuhui.bsky.social
www.science.org/doi/10.1126/...
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Functional differences between rodent and human PD-1 linked to evolutionary divergence
A highly conserved motif in human PD-1 but absent in rodent PD-1 is linked to differential inhibitory activity.
https://www.science.org/doi/10.1126/sciimmunol.ads6295
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Seth Thomas Scanlon
12 months ago
Don't miss this fantastic study by
@enfuhui.bsky.social
& colleagues published this week in
#Science
#Immunology
!
add a skeleton here at some point
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Christiana Fogg
12 months ago
First issue of
#Science
#Immunology
out for 2025! Check out this paper by Masabuchi et al. defining why rodent and human PD-1 function differently!🐀🚶♀️@enfuhui.bsky.social
www.science.org/doi/10.1126/...
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Functional differences between rodent and human PD-1 linked to evolutionary divergence
A highly conserved motif in human PD-1 but absent in rodent PD-1 is linked to differential inhibitory activity.
https://www.science.org/doi/10.1126/sciimmunol.ads6295
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Thrilled to share our
@sciimmunology.bsky.social
paper! We report that rodent PD-1 is weaker than human PD-1 (reduced ligand binding & signaling) & lacks a conserved vertebrate motif. Humanizing mouse PD-1 disrupts T cell anti-tumor responses, raising many questions.
science.org/doi/10.1126/...
12 months ago
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