When you're in Berlin, post #Candida2025, sightseeing and waiting at a random tram stop in city center, then randomly look up and see...

Ah, the day of impossible choices, aka parallel sessions. 🥺 #Candida2025

The first 24 hours of #Candida2025 have been fantastic. Really appreciate the breadth of focus of the talks and posters encompassing multiple Candida pathogens, not just C. albicans.

The preprint for our super fun collaboration with Erika Shor @mutant-fungus.bsky.social is out. Check it out to see some really beautiful PFGE karyotyping gels from Candida glabrata!

Is this thing still on? Anyway, we have a new preprint out of a story that's been brewing in my lab for several years and is finally ready to see the light of day. It's about what happens to Candida glabrata while it's hanging out inside macrophages.

Today I learned that, apparently, one way to recognize writing created by AI is to look for em dashes, because AI uses them way more than humans do. This is a problem because this human loves em dashes -- they convey connections between sentence parts like no other punctuation symbol can.

A lovely summary of our recent AAC article featured on the website of Theobald Smith Society (New Jersey branch of the American Society for Microbiology).

If you're interested in beta-glucan synthase, the target of the echinocandins, check out our new paper, where we describe some cool new aspects of its expression and regulation in Candida glabrata. journals.asm.org/doi/10.1128/...

Happening this morning: A key hearing in the cases challenging the NIH grant terminations. Plaintiffs, including multiple state AGs + researchers, are requesting an injunction to reverse the terminations. Our reporting has tracked what's at stake: projects.propublica.org/nih-cuts-res...

I've gotten Novavax in both 2023 and 2024 because it didn't give me any side effects (chills, weakness, muscle pains, etc.), unlike the mRNA vaccines. And now I'm not eligible for it. 😕🙄

Speaking to friends, I've likened the situation facing US researchers to that of the dinosaurs. We've competed for limited resources. We've adapted to our environment. We've evolved to be successful in the complex and competitive research ecosphere. And then a giant asteroid fell out of the sky.

Happy 80th anniversary of Hitler killing himself in his bunker to all who celebrate, which, as I now understand it, is not everybody

Our short commentary on #echinocandin tolerance and heteroresistance in #Candidaauris.

Thousands showed up for the #HandsOff rally in Princeton, NJ.

Will this make any difference? Is anyone listening?

New constitutional crisis, who dis?

Columbia is a test run to see what they can get away with, using federal grants as a tool for political retribution. It’s happening, and there’s a good chance that any other university is next.

Will NIH indirect costs survive in court this week? Great article on what's at play. www.science.org/content/arti...

This LinkedIn bot does not know that getting an R01 is the true pinnacle of success.

Excited to announce a save the date for the upcoming Keystone Fungal Pathogenesis meeting! Jan 12-15 2026, mark your calendars! 🗓 Program and deadlines in link below #microsky #immunosky #KSFungalPath26 🧪 www.keystonesymposia.org/conferences/...

Welcome to the Bluesky account for Stand Up for Science 2025! Keep an eye on this space for updates, event information, and ways to get involved. We can't wait to see everyone #standupforscience2025 on March 7th, both in DC and locations nationwide! #scienceforall #sciencenotsilence

Here is the pre-RFK vaccination schedule for your kids. Please download it before he is confirmed and changes/deletes it. Give it to your pediatrician and say this is the schedule you want your kids on. Making this my pinned post.

Make sure you, your trainees, and anyone else who might listen to you understands what "indirects" actually are, how they are established, and what Universities contribute. H/T @rodallab.bsky.social Please share widely! www.youtube.com/watch?v=yxTD...

Get in Dorks, we are going protesting. STAND UP FOR SCIENCE. MARCH 7th 12-4pm. DC AND YOUR STATE CAPITALS. More information to come.

Attention Attention Attention If anyone knows clinicians or patients who have knowledge of pediatric patients with the very rare cancer interdigitating dendritic cell sarcoma (IDCS) or other (non-LCH) dendritic or histiocytoc sarcomas please contact Sri

The justification here is gibberish. Philanthropic orgs don’t set their F&A rate independent of NIH. They gauge their rate based on NIH’s rate to stretch their far more limited dollars to support more research. Lowering NIH’s rate throws this balance into chaos. grants.nih.gov/grants/guide...

The checks are not checking and the balances are not balancing.

Will the order be implemented while this is going through the courts? Because we all know Congress will do nothing to stop it. Can a federal judge block it?

i'm tired of being told to stop doomscrolling. i'm just scrolling, it's not my fault there's doom on there

Per an NIH source: “Discussions with colleagues have suggested that if the universities all come together and raise hell about the delays to funding caused by not holding meetings, that might move the needle. From every state. There are well-funded universities in red states that will be impacted.”

Brilliant work by Takeharu Nagai and team: Creating coveted bioluminescence colors for simultaneous multi-color bioimaging www.science.org/doi/10.1126/...

"Nice research enterprise you got there. Shame if anything were to happen to it."

What's everyone's backup plan if the biomedical research enterprise in the US is dismantled? I have two skill sets: doing research and driving (thanks, long commutes!). So I think my backup is... Doordash? Uber? Driving a bus?

Never imagined I’d have to say this, but if you want to have a look at NIH RePORTER to see how much NIH funding your state receives so you can write to your elected representatives, you’d better do it now, and get a screenshot.

Really great about Tik Tok. Now do NIAID.

Listen to my podcast on fungal infections in this Finding Genius Podcast hosted by Richard Jacob on the below podcast platforms: * Finding Genius Website: tinyurl.com/bddjkeve * iTunes (Apple Podcasts): tinyurl.com/yey7tvfc * YouTube: youtube.com/embed/pM0n455YZVY?si @mrccmm.bsky.social

Would totally consider it if it didn't almost fully overlap with the #Candida meeting in Berlin. 😢

In mouse and gut-on-a-chip models, pre-colonoscopy bowel preparation promotes pathogen colonization of the gut and translocation to other organs https://www.biorxiv.org/content/10.1101/2024.11.26.625504v1

Very cool. I'm always looking for methods to measure microbial parameters in vivo (in the host). Wonder if this method would work in a eukaryotic microbe, or if it relies on the cell having a single origin and a single terminus...

Went looking for genome stability and/or DNA repair starter packs and found one for both! 🙌🏼

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New paper alert 👀 academic.oup.com/femsyr/advan...

I am a transplant infectious disease physician with a laboratory research program in medical mycology and mucosal immunology, with a focus on Aspergillus, and in mycobiota science. I work at MSK in NYC with a wonderful group of graduate students, fellows, and postdocs.

Sounds like NIAID will be first to go...

As on tw*tter, I have 2 bluesky accounts: one for work/science and the other for general ranting. However, if/when Dr. Fauci is arrested (as apparently he is now expecting to be), the twain shall meet.

Genomics, evolution, and more starter pack! Help build community with this starter pack. This list is currently incomplete. Want to be included? Reply and I will remedy that! go.bsky.app/JjvzkWU

I haven't been here in... almost a year? Nice to see this place coming to life. 🌱

Interesting. Possibly an(other) example of evolution of hyper-mutators under pervasive stress (antifungal treatment).

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