Bergeron lab
@bergeronlab.bsky.social
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Structural biology, and beer. Not necessarily in that order.
pinned post!
Our latest pre-print! More superb work led by duo extraordinaire Kailin and Rosa (The order of names is wrong, I should not be listed first…)
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The structure of the Vibrio alginolyticus flagellar filament suggests molecular mechanism for the rotation of sheathed flagella
In several pathogenic bacteria, including Vibriospecies, the filament of the bacterial flagellum is encased by a membranous sheath, an extension of the bacterial outer membrane. It has been proposed t...
https://www.researchsquare.com/article/rs-6983709/latest
about 1 month ago
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Our latest pre-print! More superb work led by duo extraordinaire Kailin and Rosa (The order of names is wrong, I should not be listed first…)
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The structure of the Vibrio alginolyticus flagellar filament suggests molecular mechanism for the rotation of sheathed flagella
In several pathogenic bacteria, including Vibriospecies, the filament of the bacterial flagellum is encased by a membranous sheath, an extension of the bacterial outer membrane. It has been proposed t...
https://www.researchsquare.com/article/rs-6983709/latest
about 1 month ago
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I probably shouldn’t comment on how amazing and transformative I think this work is, since I’m examining the thesis of its first author in a few weeks. So I’m not going to.
add a skeleton here at some point
3 months ago
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reposted by
Bergeron lab
King's Faculty of Life Sciences & Medicine
4 months ago
@kingscollegelondon.bsky.social
spin-out company Prosemble, co-founded by
@bergeronlab.bsky.social
has been awarded
@innovateuk.bsky.social
funding as part of the Biomedical Catalyst to transform cancer care with cutting-edge nanoparticle and AI technologies. Read more:
www.kcl.ac.uk/news/kings-s...
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King's spin-out company awarded Innovate UK Biomedical Catalyst funding | King's College London
King's College London spin-out company Prosemble, co-founded by Dr Julien Bergeron, has been awarded Innovate UK funding as part of the Biomedical Catalyst to transform cancer care with cutting-edge n...
https://www.kcl.ac.uk/news/kings-spin-out-company-awarded-innovate-uk-biomedical-catalyst-funding-1
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add a skeleton here at some point
4 months ago
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That is very cool.
add a skeleton here at some point
5 months ago
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reposted by
Bergeron lab
cryoEM papers
6 months ago
The structure of the Tad pilus alignment complex reveals a periplasmic conduit for pilus extension
pubmed.ncbi.nlm.nih.gov/40730569/
#cryoem
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The peer-reviewed version of Sash and Iryna’s paper on the Tad pilus is out:
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The structure of the Tad pilus alignment complex reveals a periplasmic conduit for pilus extension - Nature Communications
The Tad pilus is involved in the formation of antibiotic-resistant biofilms in many bacteria, including the human pathogen Pseudomonas aeruginosa. The authors report the structure of the Tad pilus pro...
https://www.nature.com/articles/s41467-025-62457-8
6 months ago
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Hmmmm… there’s a, let’s call it “interesting” new sculpture at the entrance of the
@crick.ac.uk
. I’m curious to hear what this is meant to illustrate.
7 months ago
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Superb work from our lab neighbours!
add a skeleton here at some point
7 months ago
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reposted by
Bergeron lab
King's Faculty of Life Sciences & Medicine
7 months ago
In a new study,
@bergeronlab.bsky.social
have used the world’s most advanced electron microscope to reveal the complete architecture of the bacterial flagellum - a molecular machine essential for bacteria to cause infection, that could also be a target for antibiotics ⬇️
www.kcl.ac.uk/news/scienti...
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Scientists target 'molecular machine' in the war against antimicrobial resistance
Scientists have studied a new target for antibiotics in the greatest detail yet – in the fight against antibiotic resistance.
https://www.kcl.ac.uk/news/scientists-target-molecular-machine-in-the-war-against-antimicrobial-resistance
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reposted by
Bergeron lab
Nature Microbiology
7 months ago
#NewResearch
🚨Out now! Structural analyses of the extracellular flagellum shows mechanism for flagellin incorporation
#MicroSky
🦠
www.nature.com/articles/s41...
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The structure of the complete extracellular bacterial flagellum reveals the mechanism of flagellin incorporation - Nature Microbiology
Cryo-electron microscopy analysis of the extracellular flagellum structure, including the hook–filament junction and filament cap complex, reveals mechanisms of flagellin incorporation into the growin...
https://www.nature.com/articles/s41564-025-02037-0?utm_source=bluesky&utm_medium=social&utm_campaign=nmicrobiol
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A lovely write-up from Kings about our latest paper, and its role in combating antibiotic resistance:
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Scientists target 'molecular machine' in the war against antimicrobial resistance
Scientists have studied a new target for antibiotics in the greatest detail yet – in the fight against antibiotic resistance.
https://www.kcl.ac.uk/news/scientists-target-molecular-machine-in-the-war-against-antimicrobial-resistance
7 months ago
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The peer-reviewed version of our article on the flagellum filament assembly is out! A masterpiece from duo extraordinaire Kailin and Rosa, and an incredibly productive collaboration with Marc Erhardt and Morgan Beeby.
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The structure of the complete extracellular bacterial flagellum reveals the mechanism of flagellin incorporation - Nature Microbiology
Cryo-electron microscopy analysis of the extracellular flagellum structure, including the hook–filament junction and filament cap complex, reveals mechanisms of flagellin incorporation into the growin...
https://www.nature.com/articles/s41564-025-02037-0
7 months ago
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reposted by
Bergeron lab
Nonia Pariente
10 months ago
When they go low, you go high, said a very wise woman Just goes to show how pathetic Europe is exactly 💪🏻🧪 (Well done European Commission and ERC)
add a skeleton here at some point
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reposted by
Bergeron lab
cryoEM papers
11 months ago
A family of bacterial actin homologs forms a three-stranded tubular structure
pubmed.ncbi.nlm.nih.gov/40073056/
#cryoem
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Latest paper from the lab: the Cryo-EM structure of BeeR! (Yes we did name the protein. No it’s not a coincidence)
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A family of bacterial actin homologs forms a three-stranded tubular structure | PNAS
The cytoskeleton is crucial for cell organization and movement. In Eukaryotes, it largely consists of the protein actin, that forms a double-strand...
https://www.pnas.org/doi/10.1073/pnas.2500913122
11 months ago
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reposted by
Bergeron lab
cryoEM papers
12 months ago
Curvature generation and engineering principles from Shewanella oneidensis multi-flagellin flagellum
www.biorxiv.org/content/10.1101/2025.02.07.637127v1
#cryoem
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reposted by
Bergeron lab
about 1 year ago
We are a little behind schedule, but the line up for the Next Great Wall Symposium in Sicily in September is coming together more soon. Get ready for those applications for abstracts!!!
thegreatwall-symposium.org
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The Greatwall-symposium
The Great Wall Symposium will take place from 18th to 20th September 2023 at the venue in The Vila Galé Sintra Hotel, in Portugal.
https://thegreatwall-symposium.org/
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Bergeron lab
Kate Beckham
about 1 year ago
First post of the year to mark my return from maternity leave :) Excited to share the first open PhD position in my group. Deadline end of February. Please spread the word.
www.findaphd.com/phds/projectdetails.aspx?PJID=181239
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PhD studentship: Structural and functional characterisation of mycobacterial outer membrane proteins at Newcastle University on FindAPhD.com
PhD Project - PhD studentship: Structural and functional characterisation of mycobacterial outer membrane proteins at Newcastle University, listed on FindAPhD.com
https://www.findaphd.com/phds/projectdetails.aspx?PJID=181239
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