Molecular basis of high-torque transmission of the Vibrio polar flagellar motor pubmed.ncbi.nlm.nih.gov/41871453/ #cryoem

I had Claude make this as a mini-game for Relay's disconnect screen (like Chrome's dinosaur), but then pivoted to stand-alone. In this game, you have to find Euler angles matching the target projection, i.e. cosplay RELION. It can be pretty hard. Works on mobile too! warpem.github.io/euler-hunt/

Our latest pre-print! More superb work led by duo extraordinaire Kailin and Rosa (The order of names is wrong, I should not be listed first…)

I probably shouldn’t comment on how amazing and transformative I think this work is, since I’m examining the thesis of its first author in a few weeks. So I’m not going to.

@kingscollegelondon.bsky.social spin-out company Prosemble, co-founded by @bergeronlab.bsky.social has been awarded @innovateuk.bsky.social funding as part of the Biomedical Catalyst to transform cancer care with cutting-edge nanoparticle and AI technologies. Read more: www.kcl.ac.uk/news/kings-s...

😬

That is very cool.

The structure of the Tad pilus alignment complex reveals a periplasmic conduit for pilus extension pubmed.ncbi.nlm.nih.gov/40730569/ #cryoem

The peer-reviewed version of Sash and Iryna’s paper on the Tad pilus is out:

Hmmmm… there’s a, let’s call it “interesting” new sculpture at the entrance of the @crick.ac.uk . I’m curious to hear what this is meant to illustrate.

Superb work from our lab neighbours!

In a new study, @bergeronlab.bsky.social have used the world’s most advanced electron microscope to reveal the complete architecture of the bacterial flagellum - a molecular machine essential for bacteria to cause infection, that could also be a target for antibiotics ⬇️ www.kcl.ac.uk/news/scienti...

#NewResearch 🚨Out now! Structural analyses of the extracellular flagellum shows mechanism for flagellin incorporation #MicroSky 🦠 www.nature.com/articles/s41...

A lovely write-up from Kings about our latest paper, and its role in combating antibiotic resistance:

The peer-reviewed version of our article on the flagellum filament assembly is out! A masterpiece from duo extraordinaire Kailin and Rosa, and an incredibly productive collaboration with Marc Erhardt and Morgan Beeby.

When they go low, you go high, said a very wise woman Just goes to show how pathetic Europe is exactly 💪🏻🧪 (Well done European Commission and ERC)

A family of bacterial actin homologs forms a three-stranded tubular structure pubmed.ncbi.nlm.nih.gov/40073056/ #cryoem

Latest paper from the lab: the Cryo-EM structure of BeeR! (Yes we did name the protein. No it’s not a coincidence)

Curvature generation and engineering principles from Shewanella oneidensis multi-flagellin flagellum www.biorxiv.org/content/10.1101/2025.02.07.637127v1 #cryoem

We are a little behind schedule, but the line up for the Next Great Wall Symposium in Sicily in September is coming together more soon. Get ready for those applications for abstracts!!! thegreatwall-symposium.org

First post of the year to mark my return from maternity leave :) Excited to share the first open PhD position in my group. Deadline end of February. Please spread the word. www.findaphd.com/phds/projectdetails.aspx?PJID=181239