Schiff: The judge, in that decision on Monday, referred Blanche, basically, to the New York Bar Association because of his conduct. How is it possible that after being referred to the bar association for potential discipline on Monday, we’re contemplating this guy for attorney general on Wednesday?

This #ChemEd #Chemistry #ChemSky summary introduces 1,3-dipolar cycloadditions. It builds on the Diels-Alder 1 pagers & is another [4+2] cycloaddition but gives 5-membered rings. It is only an intro. More details will be on makingmolecules.com as soon as I've typed up my notes. Enjoy!

There are only a few hours left to comment on the proposed OMB rule that would eviscerate American science. This is the single best summary, and guidance for how to write a comment, that I have seen. PLEASE submit something, even if it is only 2 or 3 paragraphs.

Lead Optimization of TgCDPK1 Inhibitors for the Treatment of Toxoplasmosis | Journal of Medicinal Chemistry pubs.acs.org/doi/10.1021/...

Reappraising Dichloromethane: Uncovering a Hidden Coupling Reagent for Activating Carboxylic Acids in Direct Amide Synthesis | Journal of the American Chemical Society pubs.acs.org/doi/10.1021/...

Congratulations to Prof. Geert-Jan Boons, who has been awarded the 2026 RSC Carbohydrate Group Haworth Memorial Lectureship #glycotime

I still think this is one of the most egregious acts of Treason ever committed….

Foundational! "The scientist doing basic research may not be at all interested in the practical applications of his work, yet the further progress of industrial development would eventually stagnate if basic scientific research were long neglected." From Science: The Endless Frontier, Bush, 1945

Global warming is real .... just slow

“We’ve only had 114 years to do something, let our kids sort it out!”

2020 FAKE ELECTORS CASE MOVES FORWARD: Three Trump allies in Wisconsin face eleven felony counts each, carrying up to six years apiece. Trump pardoned them federally—but he can’t pardon them for the state charges. They now head to trial. Full story here: www.dworkinsubstack.com/p/raskin-exp...

THIS is HUGE! Researchers at Mie University in Japan have successfully used CRISPR Cas9 gene editing to remove the extra chromosome 21 responsible for Down syndrome from human cells for the first time. The team is led by Dr. Ryotaro Hashizume. Published in PNAS Nexus

Trump’s DOJ has charged 15 anti-ICE protesters in Minnesota. The charges are based on his national security memo that categorized “anti-capitalism,” “anti-Americanism,” and “extremism on migration” as domestic terrorism. This is what tyranny looks like.

“A deliberate crippling” is a very accurate description of what Russell Vought and Jay Bhattacharya are doing to NIH. cssh.northeastern.edu/a-deliberate...

TOMORROW!!! #NoKingsDay 🇺🇸

Opportunity for computational chemist at Vertex (Oxford UK) ref: REQ-29266 | closing: 19-Jun-2026 #CompChem #cheminformatics #ML #AI #UKChemJobs #ChemJobs #chemsky 🧪 vrtx.wd501.myworkdayjobs.com/Vertex_Caree...

In this piece, @gretchentg.bsky.social @ucs.org praises the collective response from scientists to the proposed OMB rule—but says we’d “do well to apply this same level of activation to the larger assaults on science & democracy that are harming communities” 👏👏👏 blog.ucs.org/gretchen-gol...

In a report published on the first anniversary of the Bethesda Declaration, 71 staffers write that they feel NIH leadership “largely ignored" their concerns www.statnews.com/2026/06/09/n...

In case you forgot what it looks like when a real president gets the love at a game. You know, when the crowd actually wants the president there.

The most expensive taxpayer funded nap #NBAFinals

Trump’s power depends on maintaining the illusion that he’s all-powerful, and that most Americans adore him. But that illusion is harder to maintain when you're booed by thousands of fans at a basketball game in your hometown. The Emperor has no clothes. He is not all powerful. Remember this.

Blanche announced the DOJ would not be releasing the 2.5 million remaining Epstein files in its possession, saying the department had "moved on."

RFI: Proposal to Cap the Number of Simultaneous Research Project Grants per Principal Investigator to Support More Researchers and Maximize Scientific Productivity and Innovation grants.nih.gov/grants/guide...

Holden Thorp is an institutionalist. He's been a university chancellor, provost, now EiC of Science. When institutionalists pull the fire alarm, we listen, because the call to action he issued this week exposes the dire nature of the threat we are facing. 1/ www.science.org/doi/10.1126/...

Russell Vought has a plan for science, but so do we. Join the fight by joining our Emergency Science Meeting AND taking action against the latest OMB grant funding proposal here 👉 zurl.co/NWZp0 Donate to our fight here 👉 zurl.co/muvwU

The Current Crisis: What's Happening to Science in America | Science | AAAS www.science.org/content/blog...

In the end we were just his latest casino and whatnot.

You will never hear, see this on Fox, Newsmax or any other rightwing channel.

Marty Makary went on Fox News and lied to all of us, saying that 10 children died from COVID19 vaccines. The report actually said, “No cases [of pediatric deaths] were classified as certain in relation to COVID-19 vaccination”. Makary also said that FDA approvals were a “mockery of science”.

So we all know acid can remove a BOC… What if you have acid labile groups? Check out this #PfizerChemistry #JOCasap using HFIP and low eq acid to remove PGs - shorter rxn times and cleaner profiles Oh you’ve got a PMB? Check! CBZ too! No hydrog needed #ChemSky

🤔 #Epstein #EpsteinFiles

The way this regime ignores the First Amendment is outrageous.

ZERO 👇 LIES DETECTED HERE.....

I think this is 100% correct.

. I don’t know who needs to hear this, but it isn’t a ballroom It’s a bunker so he doesn’t have to leave the White House when his term is up. #CONGRESS!!! Get him out of that house now. .

Here’s one explanation.

Am I understanding this correctly? The President, the Vice-President, the Speaker of the House AND the Secretary of Stare were all at the White House Correspondent's Dinner together and security was so laxed that a guy ran through security with a long gun? I call bullshit.

Q: Maybe Americans should think twice before voting for a demented octogenarian sociopath. A: Maybe Americans should THINK before they cast a vote in a presidential election. It’d be great if the candidate had more positives than just, “He hates the same people that I do.”

Has Trump Tried, Self Impeachment 🤔........

RFK Jr: I terminated the COVID vaccines because it didn’t make any sense. COVID is gone. Note: From July 2024 to June 2025 in the US, COVID19 caused up to 450,000 hospitalizations and 53,000 deaths. COVID ain’t gone, shitbird.

New York Times article about the slow pace on NIH grant making as well as enforcement of political constraints. [Gift Link] www.nytimes.com/2026/04/22/s... 1/4

Today, our #SCIMaP team released an impact analysis of the White House proposed FY 2027 NIH and NSF budgets. Bottom-line: if enacted, cuts to science and medical research would lead to $35B in economic losses and 150,000 lost jobs in communities all across the US. scienceimpacts.org 🧵

Jay Bhattacharya has ordered that a paper showing the effectiveness of COVID19 vaccines in preventing severe disease and hospitalization be suppressed and hidden. This man has been crying nonstop about political censorship for 6 years. But he’s the one who is actually doing it.

Insider trading is illegal... but they don't care