I am delighted to share a publication in @natcomms.nature.com. IRX3, linked to obesity via the FTO locus, influences fat vs bone cell fate. It is the result of a wonderful collaboration between S. Dankel, G. Mellgren @unibergen.bsky.social and my lab @biovitenskap.bsky.social 🍾 👉 rdcu.be/ezA5o

We are extending the application deadline for this post-doc position! Do not miss the opportunity to join an exciting project in a dynamic and collaborative research environment. @igbmc.bsky.social @pasteur.fr @univbordeaux.bsky.social @uio.no #epigenetics #cellfate #SUMOylation @ncmbm.bsky.social

Totipotent-like cells in early mouse embryos reorganize their genome via Z-DNA and Zscan4-driven interactions to form a “Z compartment” first supporting ZGA and later compartmentalisation to safeguard the totipotent-like state. Chromatin plasticity at its finest! www.biorxiv.org/content/10.1...

We’re Hiring! I am seeking a Pos-doc Researcher in Molecular Biology and Epigenetics. Join our team @biovitenskap.bsky.social @uio.no to explore how SUMOylation regulates epigenetic fate, gene expression, 3D-genome and chromatin during adipogenesis, with implications for obesity and cancer research.

This study is a very elegant characterisation of the epigenetic and transcriptional divergence between white and beige adipocytes. Very useful to those studying the epigenetic mechanisms supporting cellular reprogramming. www.biorxiv.org/content/10.1...

Genome sequencing & single-cell transcriptomics continue to produce findings that challenge the idea that #cancer is purely a genetic disease. This Essay delves into #omics data that questions the somatic mutation theory & presents alternative theories based on GRNs & tissue fields.🧪 plos.io/3DRtAEW

Our recent in vivo study reveals that inhibiting SUMOylation with TAK-981 disrupts fat accumulation, leading to impaired adipogenesis and increased immune cell infiltration in perigonadal white adipose tissue. www.tandfonline.com/doi/full/10....

My group @biovitenskap.bsky.social is #hiring a Post-doc in bioinformatics and biostatistics to work on #epigenetic memory in stem cells and during cell reprogramming. The position is co-supervised by @amathelier.bsky.social from @nordicembl.bsky.social

Thanks for sharing the first of the two positions that we will propose in the next 6 months @biovitenskap.bsky.social Stay tuned!

As part of this initiative, two postdoctoral fellowships will soon be advertised. One focusing on Molecular and Cell Biology, and one focusing on bioinformatics and biostatistics. Stay tuned for more updates and details about these positions! @chymkowitchlab.bsky.social www.mn.uio.no/ibv/english/...

Oslo skeeps. We will host @michaelhoffman.bsky.social on Mon. Jan. 27th. Looking forward to his seminar about "Identifying transcription factor binding using open chromatin, transcriptome, and methylation data." You can also book a time to meet him. More info at www.mn.uio.no/bils/english...

Three more days to register and submit your abstract for the upcoming TriRhena Gene Regulation Club. #epigenetics

Single molecule approaches across the central dogma! Genomics, imaging and theory! Very excited to host the first edition of Gene regulation, one molecule at a time this July @embl.org! Great lineup and many abstract selected talks!

Instead of listing my publications, as the year draws to an end, I want to shine the spotlight on the commonplace assumption that productivity must always increase. Good research is disruptive and thinking time is central to high quality scholarship and necessary for disruptive research.

Many workplaces have parties or team meals to celebrate the end of the working year, but some show true appreciation by cultivating group traditions. Nature asked group leaders to explain these, and how they thank colleagues for their hard work. #AcademicSky

6️⃣0️⃣ Marie Skłodowska-Curie (1867-1934) 🇵🇱🇫🇷 #womeninSTEM The most famous scientist in the world. 1st woman professor at Sorbonne, only woman to win the Nobel in 2 different fields. During WWI, she invented a mobile X-ray unit that could travel to the battlefront. www.nobelprize.org/womenwhochan...

Congratulations, Pierre @chymkowitchlab.bsky.social. It's a fantastic news indeed! I look forward to continuing to collaborate with you on this great project. Bioinformaticians/data scientists: stay tuned for an upcoming postdoc position to analyze cool multi-omics data supervised by Pierre and I!

Very exciting; I strongly recommend!

🎄 What a fantastic Christmas gift! Our #FRIPRO application on the regulation of epigenetic fate by #SUMOylation has been awarded 12MNOK by the Research Council of Norway!

Thousands of people have donated to rebuild Notre-Dame de Paris, including me. But there are hundreds of heritage sites that deserve our attention. Why not make small donations to support projects like this surprising pagoda in the heart of France? www.fondation-patrimoine.org/les-projets/...

Superb story studying obesity from an epigenetic memory angle rdcu.be/d2Jun

By definition, enhancers can activate from a distance. But with increased distance between enhancer and promoter, the activation drops. To study this systematically, we build a synthetic locus: www.cell.com/molecular-ce... 1/12

A superbe afternoon sun over the Oslo fjord during the retreat of the BMB section. Thanks to all speakers and poster presenters for their contribution 👏👍 @biovitenskap.bsky.social

@arnaudkr.bsky.social and I have been talking about organizing a single-molecule genomics meeting for years! We're excited to do so at EMBL while bridging the fields of single-molecule genomics and microscopy with our co-organizers. Hope to see you there! July 15-18 www.embl.org/about/info/c...

My first post on Blue Sky - moving over ! For all post-docs out there - fantastic opportunity @EMBL. Independent group leader position: Core funding, state-of-the-art core facilities, access to fantastic Ph.D. students, and of course amazing colleagues. Please apply www.embl.org/jobs/positio...