Nature research paper: Robot-assisted mapping of chemical reaction hyperspaces and networks go.nature.com/3Iy42Pw

Aaand it's out! Meet MITE - the natural product tailoring enzyme database, just published in @narjournal.bsky.social! MITE DB captures the substrate- and reaction-specificity of tailoring enzymes, allowing to capture this information in a human- and machine-readable way! doi.org/10.1093/nar/...

🚨 Great fellowship opportunity for grad students! 🎓 A lot of folks are aware of the NSF GRFP but a lot less are aware of the similar DoD NDSEG. 💡 This competitive fellowship covers stipend and travel. It's a seriously great resource that not enough students know about. ndseg.sysplus.com

Host-specific microbiome and genomic signatures in Bifidobacteriumreveal co-evolutionary and functional adaptations across diverse animal hosts www.cell.com/cell-host-mi...

We had a super fun September biotech meetup, and October is officially scheduled. Here’s a link to the September recap and details for October: twincitiesbiotech.substack.com/p/september-...

🚨 New blog post is live! 🤔 In this one I reflect on using science and adaptability to build successful startups and innovation programs (including those in large companies)! ✨ I had a lot of fun writing this one! 👀 Be sure to check it out! livingbio.substack.com/p/building-s...

To anyone in the Minneapolis Startup community, or anyone who wants to learn more about startups (especially students), there is a great meetup happening in September! Details on the event page: lu.ma/n40cxaem?tk=...

We had an awesome time at the Twin Cities Biotech meetup yesterday evening, this time at Pryes Brewing! Be sure to signup for our meetup SubStack, which is the best way to keep updated on upcoming meetups! twincitiesbiotech.substack.com

If anyone is looking for an awesome biotech networking event in Minnesota, be sure to checkout the Twin Cities biotech meetup! We have our next event tomorrow! They are always a lot of fun! twincitiesbiotech.substack.com/p/its-time-f...

A note to any founders who are eager to tell their story to a room full of investors, corporates, founders, an more! Applications are open to present at our upcoming Medical Alley Innovation Showcase on September 22! Applications close on August 14th! forms.office.com/r/g5d4NAC3kT

What happens to the colossal stash of C- and N-rich (but chemically inaccessible) chitin generated by the global insect population? Love this @plosbiology.org paper from Justin Nodwell & co which shows that #Streptomyces have the equipment to exploit it...

Jennifer Readshaw nuclease now shown BREX and beyond block phages mystery cracking #sciku 🧪🧬🔬🧫🦠 #Phages2025 doi.org/10.1093/nar/...

🚨 New blog post alert! 👀 Checkout my deep dive into AI for human-pathogen interaction modeling at the protein level! Based on a cool recent pub in @plos.org Comp Bio! 🧫 This was a lot of fun to write, as I continue along this theme of protein analytics! livingbio.substack.com/p/fighting-p...

Elucidating #plant #Biosynthetic pathways: @jjjvanderhooft.bsky.social @marnixmedema.bsky.social &co develop #MEANtools, an unsupervised computational workflow that integrates #MultiOmics data to predict #metabolic pathways by linking transcripts to metabolites @plosbiology.org 🧪 plos.io/4odL94g

It was great fun writing this review with @gemccallum.bsky.social , even if our conclusions are rather scary. Lots of important pathogen evolution must be occurring outside of the infection context...

Our new Collection on #cancer is out now! We delve into how #omics technologies are helping researchers to better understand what goes on in the tumor microenvironment 🧪 See 🧵⬇️ for more info on the articles 1/9 plos.io/4mgHDEw

After 15 years of controversy, @science.org retracts ‘arsenic life’ paper

Karolinska is looking for 20 (!!) assistant professors and offering 6 year appointments with ~1M USD startup packages. ki.se/en/about-ki/...

Fascinating new paper reveals a new gut microbiome connection to heart disease. Microbes produce imidazole propionate (ImP), which directly triggers atherosclerosis through immune activation - even without high cholesterol. www.nature.com/articles/s41...

Sassy is out now! Ever need to search for approximate matches of short DNA strings? Sassy is the tool to use! Available now wherever you get your code With @rickbitloo.bsky.social curiouscoding.nl/papers/sassy... github.com/ragnarGrootK...

Save the date, for anyone in Minnesota next June! This is a pretty interesting conference

Out in @natbiotech.nature.com: Metagenome taxonomy profilers usually ignore unknown species. SingleM is an accurate profiler which doesn't, even detecting phyla with no MAGs. Profiles of 700,000 metagenomes at sandpiper.qut.edu.au. A 🧵

New RESOURCE! Integrative genomic reconstruction reveals heterogeneity in carbohydrate utilization across human gut bifidobacteria @arzamasovalex.bsky.social @drlarsbode.bsky.social Andrei Osterman, Jeff Gordon & co #microbiomesky #microsky www.nature.com/articles/s41...

Preprint: “Structural modeling reveals viral proteins that manipulate host immune signaling” Using AI-guided structural modeling, we find new families of viral proteins that sequester or cleave host immune signaling molecules Congrats Nitzan Tal! www.biorxiv.org/content/10.1...

I saw an infographic a couple years ago about how to remove source identifiers from links and why it's important, but I can't find it again and too many people I know are sending me links with them so here's an infographic straight from the oven

🚨 New blog post alert! Some perspectives and takeaways from a recent spatial proteomics paper (Deep Visual Proteomics) and the trajectory of the technology over recent years! livingbio.substack.com/p/deep-visua...

Awesome opportunity for high school, college, and grad students! lu.ma/uncdjt89

The Biotech Innovation Organization (BIO) met this June for the annual international BIO convention, and it was an experience! Checkout the latest Living Bio blog post! A reflection full of highlights, trends, and insights from my attendance. livingbio.substack.com/p/reflection...

Most #biosynthetic gene clusters remain uncharacterized. @marnixmedema.bsky.social @gillesvanwezel.bsky.social &co integrate #GRN analysis & global expression data to identify desJGH as an operon essential for #biosynthesis of #desferrioxamineB in Streptomyces @plosbiology.org 🧪 plos.io/43UVUPB

New pre-print out \o/ All about CRISPR, metagenomes, and what you learn when you collect (a lot of) spacers from natural communities, with @apcamargo.bsky.social @urineri.bsky.social @lhug.bsky.social but also Uri Gophna, Nikhil George (not on Bsky I think) & others at JGI doi.org/10.1101/2025...

Hello friends and biotech enthusiasts! Online is great but live meetups are even better! If you’re in the Twin Cities this summer, it would be great to have you join the next mixer in this growing biotech community! You can sign up for future updates and alerts as well lu.ma/c2sjjoud

🚨 New Blog Post Alert! 🚀 Today I posted some themes and reflections from the recent Mayo Clinic Innovation Summit, including sentiment, partnership tactics, and technical advancements! 👀 Be sure to check it out! livingbio.substack.com/p/teamwork-m...

🚨 New blog post alert! 🤔 Curious about what it takes to start a podcast? 🧰 Want to get started but not sure what tools to use? 📝 This post covers reflections and lessons learned in the science podcast space! 👀 Be sure to check it out! livingbio.substack.com/p/how-to-mak...

Fresh in @NatureBiotech! We developed a synthetic biology tool for tracking gene transfer in microbial communities and applied it to study plasmid hosts in a wastewater microbiome. Awesome collab with James Chappell & @joffsilberg.bsky.social and incredible students. www.nature.com/articles/s41...

Unique investigation of some errors in long read assemblers. In particular these remarkably chimeric contigs are 😱, if rare.... Improving long read assemblers is definitely the space to be in when it comes to the future of metagenomics, as short reads won't be part of it 😉

AFESM: a metagenomic guide through the protein structure universe! We clustered 821M structures (AFDB&ESMatlas) into 5.12M groups; revealing biome-specific groups, only 1 new fold even after AlphaFold2 re-prediction & many novel domain combos. 🧵 🌐 afesm.foldseek.com 📄 www.biorxiv.org/content/10.1...

🚨 A new blog post is live! 🤔 In this post I reflected on some recent trends across biotech and techbio startups, and provided some really cool citations for additional reading. 👀 Be sure to check it out! livingbio.substack.com/p/three-curr...

I haven't blogged in a while, and honestly I've missed it. I have evolved my blogging over the years, and now I'm excited to be relaunching the latest version under a new name (previously Prophage)! I will be writing about all things biology, data, & health! livingbio.substack.com/p/hello-worl...

Had a chance to join this cool investor forum yesterday. Worth checking out, especially for those interested in the northeast + midwest ecosystems. Startups ranging from cancer diagnosis to high speed transport. #startups #science kfmwne.com

🤔 How are you collaborating and building trust with your colleagues? 🤝 Are you fostering a productive and connected environment for your teams? 🌐 These are really important questions that we discussed in a recently posted episode of Planet Bio. #podcasting podcasts.apple.com/us/podcast/p...

🚀 The Planet Bio team is launching into the new year with a string of new weekly episodes! Checkout our latest episode, exploring the importance of balancing data with models when leveraging #AI in the life sciences. open.spotify.com/episode/10oM...

Autoencoders can be powerful #MachineLearning tools, with applications in molecular design, complex omics analyses, and beyond. Checkout this post for an overview of Sparse Autoencoders and their applications for model interpretability. adamkarvonen.github.io/machine_lear...

My collection of previously published stories, Junk Birds and other stories has become! a.co/d/7ctoykD

Excited to share GenomeFISH: genome-based fluorescence in situ hybridisation for strain-level visualisation of microbial communities. @sjmcilroy.bsky.social, @benjwoodcroft.bsky.social, @jamesvolmer.bsky.social doi.org/10.21203/rs.... 🧵1/6

Enjoying this deep dive into the link between coffee and the microbiome They found a microbe (Lawsonibacter asaccharolyticus) that is 4- to 8-fold more abundant in coffee drinkers, and correlates with coffee intake in worldwide populations www.nature.com/articles/s41...

We've updated our manuscript Microbial interactions affect the tempo and mode of antibiotic resistance evolution www.biorxiv.org/content/10.1...

Absolutely thrilled to have won the @einsteinberlin.bsky.social Individual #EinsteinFoundationAward. Big congrats to PubPeer and @helenajambor.bsky.social for winning in their categories.

💡 Whether you’re in academia and looking to jump into industry, or already in industry and looking for a new role: 👀 Great colleague of mine is hiring for “Senior AI/ML Data Scientist, Natural Language Processing” Details in the link #sciencejobs msd.wd5.myworkdayjobs.com/SearchJobs/j...

"It appears that your recommended reviewers are not really your friends, Mr. Bond"

👀 Big news from Tempus AI! 🤝 Tempus (precision medicine) announced a big cash/stock purchase of the hereditary cancer screening company Ambry Genetics. 🧬 Also worth noting Ambry is the main reference lab in the category for Tempus. www.medtechdive.com/news/tempus-...