@ewanbirney.bsky.social on the new version of Alphafold at the @emblebi.bsky.social www.ebi.ac.uk/about/news/t... AlphaFold has been a transformation not just in structural biology but also - due to its ability to be applied to all proteins - to molecular biology as a whole.

Epigenetics Update - Plant mobile domain protein–DNA motif modules counteract Polycomb silencing to stabilize gene expression go.nature.com/3IzfbQe #Epigenetics #Chromatin #Plants #Polycomb --- Discover the breakthrough at epigenometech.com

How do SMC complexes load onto DNA to get ready for loop extrusion? @roisnehamelinf.bsky.social & co discovered that Wadjet, an SMC complex involved in bacterial DNA immunity, performs some impressive molecular gymnastics 🤸‍♂️🤸‍♂️🤸‍♂️. Check out the new paper: www.cell.com/molecular-ce...

Our paper is finally out in Nature Plants. MAIL proteins antagonize Polycomb-mediated silencing. Full text here: rdcu.be/eJisX

In case you missed it, our workshop on Fiji Basics for Visualization and Quantification of Plant Images is now available on YouTube: www.youtube.com/watch?v=4TMJ... We give a lot of practical tips on how to get started with Fiji. Keep an eye out for announcements on follow-up workshops.

A part of our team at the recent EMBO SUMO conference in La Grande Motte/Montpellier

🚀 We’re hiring a Postdoc! Join our group in Poznan, Poland to study meiotic crossover recombination in plants 🌱 Highly motivated & enthusiastic candidates are welcome! 📅 Deadline: Nov 1, 2025 🔗 ibmib.web.amu.edu.pl/wp-content/uploads/2025/09/Postdoc_position-2025-Ziolkowskis-Lab.pdf

"Work hard, play harder!"🔥 Teamwork doesn’t stop at the office. A great night of laser tag and dinner with colleagues. Turns out that Eva @evadt.bsky.social is laser tag assassin.🥷 #YouCanShootYourBoss #TeamSpirit

💡🔬 TECHNICAL INNOVATION 💡🔬 Neubauer et al. developed a Nostoc reporter strain enabling high-throughput quantitative monitoring of hormogonia differentiation in cyanobacteria as a response to biotic and abiotic factors. 🔗 doi.org/10.1093/jxb/... #PlantScience 🧪 @peterszovenyi.bsky.social

🔥 The #EMBOSUMO workshop kicks off TODAY! 🎉 Thanks @embo.org @biologists.bsky.social @proteocure.bsky.social @sebiology.bsky.social @newphyt.bsky.social @umontpellier.bsky.social @occitanie.bsky.social for their support. More info: meetings.embo.org/event/25-sum...

Opening of the #EMBOSUMO meeting by Guillaume Bossis meetings.embo.org/event/25-sum...

📌 Project aim: Functional analysis of key DDR transcription factors in barley (Hordeum vulgare) using cutting-edge methods. 🌾 Supervision: Dr. Aleš Pečinka 📍 Institute of Experimental Botany, Olomouc, Czechia 🇨🇿 🔗https://olomouc.ueb.cas.cz/en/research-groups/pecinka-group

Why join? ✅ Europe-wide MSCA DN network (Heat DDR) ✅ Collaborate with leading DDR labs ✅ Training: barley genetics (transformation, CRISPR), RNA-seq, ChIP-seq, live confocal microscopy & more

📝 Selection process • Send CV + motivation letter → [email protected] • The start date is negotiable, but no later than 1.1.2026 • Only the candidates considered for interview will be contacted

🚨 PhD researcher wanted! Join the Heat DDR MSCA DN to study plant DNA damage responses – key for crop resilience & food security in a changing climate. 🌱🔬 👉 Apply now! 🔗 tinyurl.com/PecinkaHeatDDR

We’re excited to share our new work on how plants restore cytonuclear balance after whole-genome duplication. Using Arabidopsis auto- and allopolyploids, we uncover distinct, organelle-specific strategies in chloroplasts and mitochondria across generations. doi.org/10.1111/tpj....

So happy to share the outcome of an incredible team effort! In this paper we present an Atlas describing how SUMO-PTM components coordinate stress responses in Arabidopsis root cells. Huge congratulations to everyone involved! Amazing work all around! www.science.org/doi/10.1126/...

Bercin’s techique paper is here www.cell.com/molecular-ce... /22

At this point, I bet you can bottle horse dewormer, call it CureAll, and sell it on pharmacy shelves, and there would be no consequence. Oh wait! They already do that, with endorsement from a dude with worms in his brain!

It is not always safe to repair DNA Damage. Sometimes, cells "just bypass it". During DNA replication, repair of lesions on DNA can be dangerous. Cells instead "tolerate" DNA damage and focus on finishing replication. Read our review and find out why and how: doi.org/10.1016/j.ti...

Wow, maybe genomic imprinting as we know it is just the tip of then iceberg. Hopefully this helps usher in a wave of mechanistic studies www.nature.com/articles/s41...

One of my first live imaging of Arabidopsis gynoecium www.nature.com/articles/s41...

Attention plant proteomics specialists: We are looking for a Head of our new Proteomics Unit at our international and dynamic Max Planck Institute of Molecular Plant Physiology. @mpi-mp-potsdam.bsky.social Applications are welcome until 30. Sept 2025: jobs.mpimp-golm.mpg.de/jobposting/8...

Job alert 📣 Our faculty looks for a Junior Professor W1 with tt to W2 in Membrane Biology! We are looking for #ECRs working on membrane biogenesis,contact sites,composition & other aspects of membranes in 🌱 and other organisms! DM me if you need more details! jobs.ruhr-uni-bochum.de/jobposting/f...

Three #Master2 #internship topics are available in our team to study the #adaptations associated with #plant #terrestrialization 👇

Sometimes DNA replication hits a 🛑 roadblock. Cells don’t stop; they take clever detours (DNA damage tolerance) 🚗💨 to keep genomes intact. That’s the focus of our new review in @cp-trendsbiochem.bsky.social: “Just bypass it: mechanisms of DNA damage tolerance” 🔗 doi.org/10.1016/j.ti...

The identification of the very conserved CTF18, SGO2 and SPF2 as suppressors of centromere-proximal crossovers highlights the importance of cohesin turnover in this process and opens up new possibilities for plant breeding. Much more in the paper : www.biorxiv.org/content/10.1...

In WT plants, expansion microscopy with spindle immunolabeling showed microtubule connections between spindle poles and the apicobasal cortex.

Six more years—plus a lot of blood, sweat, and tears—later, we are thrilled to finally share it: a cytological framework of female meiosis in Arabidopsis! www.biorxiv.org/content/10.1...

🌱 Curious about plant biology? Explore epigenetics, stress responses & priming this February in Amsterdam! 🎤 Great speakers + oral & poster slots from selected abstracts. 9-10 February 2026 - Don’t miss it! Deadline for Abstract submission: 1 November 2025.

Great paper by the Vaziri lab about the role of RNF25 regulating the DDR independently of its E3 ligase activity! www.nature.com/articles/s41...

DNA methylation at #retrotransposons protects the #germline by preventing NRF1-mediated #activation. -> www.embopress.org/doi/full/10....

Hi-reComb: constructing recombination maps from bulk gamete Hi-C sequencing. #HiC #RecombinationMaps #GameteSequencing #Genomics #Genetics academic.oup.com/genetics/adv...

Interesting: Cu2+-binding sites on SUMO connecting multiple SUMOs together.

Congratulations to Matyáš Fendrych! 🎉 Since his departure from @istaresearch.bsky.social in 2017, Fendrych has continued his research back in CZ where he now leads a group at our Institute of Experimental Botany. #RapidAuxinSignaling Details ➡️ www.avcr.cz/en/media/pre...

Polycomb repressive complex 2 facilitates the transition from heterotrophy to photoautotrophy during seedling emergence (Naseem Samo , María Guadalupe Trejo-Arellano , Lenka Gahurová , et al) doi.org/10.1093/plce... #PlantScience

I am thrilled to share our review with @claudiakohler11.bsky.social in which we discuss on the latest research on the classical and emerging roles of transposable elements in shaping genomic imprinting in plants. www.sciencedirect.com/science/arti... #imprinting #epigenetics #plantReproduction

This is such bullshit. #NIH grants are not handouts—they are earned with lots of sweat and tears and deemed worthy by the scientific community to advance our future. Fuck this administration. www.latimes.com/california/s...

⭐NAR Breakthrough!⭐ Bonato et al. propose a model for how the yeast #condensin SMC complex drives persistent #DNAloopextrusion, using #atomicforcemicroscopy and #moleculardynamics. Read the full article here: doi.org/10.1093/nar/... #NARBreakthrough #SMC #biophysics #genomefolding #yeast

New Article: "Identification of the cytoplasmic motor–LINC complex involved in rapid chromosome movements during meiotic prophase in Arabidopsis" rdcu.be/ex4lg ... a complex composed of the kinesin PSS1, the KASH protein SINE3 and the C-term SUN-domain proteins.

Happy to see our latest work out in @molbioevol.bsky.social. We revisit the evolution of 5-methylcytosine across neglected eukaryotic supergroups, establishing an ancestral repressive role silencing genome invaders, both transposons and viral elements👾: academic.oup.com/mbe/advance-... 🧵 1/7

Is plant single cell/nuc. & spatial transcriptomics your passion? Do you want to understand plant adaptation using cutting edge molecular & bioinformatics tools? Then come and join us to work together with @ceplas.bsky.social & @wggc-de.bsky.social. #plantjobs www.fz-juelich.de/de/karriere/...

Recently I learnt that EMBL-EBI has a free online course about AlphaFold — how it works, strengths and limitations, how to use it — and it's very good! There are also little quizzes and interactives. www.ebi.ac.uk/training/onl...

Priceless! 😆 For all you #paleobiology parents.

Are you a #PhD student in #Chile and want to develop your #SoftSkills? Learn about #ScienceCommunication, #ethics, #creativity, #career #opportunities and more at the EMBO PhD Course in Chile! 🧪 Deadline extended to 27 July! Apply now: meetings.embo.org/event/embo-p...

Previous studies of extrachromosomal circular DNA #eccDNA in #plants are based on short-read seq. @vanderschuren-lab.bsky.social uses long-read seq to obtain a map of full-length eccDNAs from #Arabidopsis, identifying their genomic origins & epigenetic regulation @plosbiology.org 🧪 plos.io/44Mq3RI

AI will further slow down scientific progress. Particularly breakthrough discoveries will be hindered.

Today - THE ugly. Western blot will never be my most favorite technique 😭😭😭