#microsky #phagesky Jumbo #phage PhiKZ www.nature.com/articles/s41...

Excited to share the last installation of my PhD work. Worked with an all-star team on this one who really made this all come together beautifully. @ranidreamer.bsky.social @amardeeep.bsky.social @benadler.bsky.social and many others. www.cell.com/cell-reports...

Bacteriophages are normally classified as either virulent or temperate. Reality is, of course, more complicated! Here we show many bacterial isolates contain non-temperate phages that can persist through restreaking. Thanks to all co-authors for such a great collaboration!

Join the Reck-Peterson lab in NYC as a HHMI Research Technician! This role will support our new work on the cell biology of secondary metabolite production in filamentous fungi. Apply here: hhmi.wd1.myworkdayjobs.com/en-US/Extern...

@peterfineran.bsky.social and colleagues develop Tn-seq for phages by leveraging anti-CRISPR (Acr) as a positive selectable marker in the presence of CRISPR-Cas counter-selection, and identify essential genes in phage from non model orgs www.biorxiv.org/content/10.6...

Looking for a POSTDOC to work on jumbo phages (those with large genomes and fascinating cell biology), using our latest ASO technology (Gerovac M et al. 2025 Nature) to define RNA export mechanisms as well as to help to advance phage therapy. Here's the job ad.

Nucleus-Forming Phages: From Subcellular Organization and Viral–Host Interplay to Prospects for Phage Applications. Some new perspectives on chimalliviruses from our awesome longstanding Thai collaborators (and me). authors.elsevier.com/c/1mIJB4tPFp...

Powerful and important piece by an outstanding physician, scientist, and human being @kaminskimed.bsky.social pdf: jeremymberg.github.io/jeremyberg.g...

Super cool paper by @benadler.bsky.social @erinedoherty.bsky.social #phage #phagesky

CURIOUS ABOUT PHAGE BIOLOGY!? CPIC lab at @helmholtzhzi.bsky.social is recruiting in the call +++ CURIOSITY IS INFECTIOUS +++ helmholtz-hzi.de/en/career/jo... Did you spot the phage? Please share!

Looking for a new approach to studying or eliminating phages? Check out our study introducing anti-phage ASOs (antisense oligos) out in @Nature today. nature.com/articles/s4158…

Please share my 1 min video on the importance of maintaining NIH funding of infectious diseases and drug discovery research vs rising antibiotic resistance Drastic budget cuts harm our health and imperil the next generation of scientists More @UCSanDiego “Behind Every Breakthrough” bit.ly/3FlXQs3

Part of the recently completed PhD thesis of outstanding UC San Diego Medical Scientist Training Program student Alex Stream exploring Strep A molecular pathogenesis and vaccinology journals.asm.org/doi/10.1128/...

Seems like precisely the kind of person that HHS should want giving advice on structural/cell/molecular biology and more. That would require a leadership group that values disciplinary competency and independent expertise. villalab.ucsd.edu

This is why I always have to filter my BLAST results. Nice analysis and interesting questions about the persistence of lytic phages in host populations. I suspect for chimalliviruses it's a product of longer latent periods and low infection efficiencies in many hosts.

"That telomere phages are so prevalent means that they are a selective force, one that we know little about. We now want to understand how the telomere-toxin is secreted and also understand how this ‘telocin’ wheedles its way into unsuspecting bacterial neighbors” www.science.org/doi/10.1126/...

Pleased to share our new paper out in 𝘑𝘰𝘶𝘳𝘯𝘢𝘭 𝘰𝘧 𝘊𝘭𝘪𝘯𝘪𝘤𝘢𝘭 𝘐𝘯𝘷𝘦𝘴𝘵𝘪𝘨𝘢𝘵𝘪𝘰𝘯 led by Monika Kumaraswamy, MD, now Chief of Infectious Diseases UTexas-Tyler Is minimimum inhibitory concentration (MIC) testing the gold standard for antibiotic-resistant superbugs? 🦠 🧫 🧵 1/6 www.jci.org/articles/vie...

We teamed up with our pals at @ucsandiego.bsky.social to show how jumbo #phages – huge viruses that prey on bacteria – use sneaky tricks to attack their victims! This knowledge could be used to leverage them as a tool to fight antibiotic resistance. Read more here: ow.ly/6VLa50Vucc5 🦠

Our work on cryptic infection of giant viruses was published today in @ScienceMagazine . We discovered a large virus hiding within a green algal genome producing virions. Collaborative effort spearheaded by Virginia Tech, University of Miami & NIOZ scientists. www.science.org/doi/10.1126/...

Interrupting your regularly scheduled doom scrolling for some cool science by my awesome colleagues www.cell.com/cell-host-mi...

Anyone who puts a reddit AMA on their CV should be immediately disqualified from holding a policy position.

Flashy words like "revolutionize" are thrown around quite liberally in our field. In this case though, I can't think of a more appropriate word. This stuff is 🔥🔥🔥.

𝐓𝐨𝐩 𝐂𝐚𝐮𝐬𝐞𝐬 𝐨𝐟 𝐃𝐞𝐚𝐭𝐡 𝐢𝐧 𝐔𝐒𝐀 𝟏𝟖𝟓𝟎𝐬 Tuberculosis Dysentery Cholera Malaria Typhoid Pneumonia/Flu Diphtheria Scarlet fever Meningitis Whooping cough 𝙎𝙖𝙣𝙞𝙩𝙖𝙩𝙞𝙤𝙣/𝙑𝙖𝙘𝙘𝙞𝙣𝙚𝙨/𝘼𝙣𝙩𝙞𝙗𝙞𝙤𝙩𝙞𝙘𝙨 𝐓𝐎𝐃𝐀𝐘 Heart disease Cancer Accidents COPD Stroke Alzheimer’s Diabetes Pneumonia/Flu Kidney disease Suicide

When I started my PhD, we knew exactly zero about the phage nucleus protein import pathway. Out today in Nature, parallel work by Claire Kokontis picking apart this pathway. PicA vs. Imp1, let the games begin. www.nature.com/articles/s41...

Amazing story of a young cancer patient's resilience, a scary infection with MDR 𝘗𝘴𝘦𝘶𝘥𝘰𝘮𝘰𝘯𝘢𝘴 𝘢𝘦𝘳𝘶𝘨𝘪𝘯𝘰𝘴𝘢 expressing NDM-1, and successful application of phage therapy Care coordinated by Peds ID specialist and UCI Asst Prof Chulie Ulloa, MD—friend and former PSDP, K08, and UCPPFP mentee in the lab

Me: If this experiment works the first time, I'm throwing a party. Experiment: Did somebody say party?

I prefer shameful self-promotion by re-posting, but Pew and UCSD Biosciences have not migrated to this new utopia, so... Exciting news! I get to play with one of my besties @thevillalab.bsky.social today.ucsd.edu/story/kimber...

Excited to share our new study with the Müller and @SchullerJm labs, online @nature: https://www.nature.com/articles/s41586-022-04971-z This is T. kivui, an anaerobic bacterium. It uses hydrogen energy to store #CO2. How does it do it? #CryoET revealed membrane-anchored bundles of...

Structural diversity and oligomerization of bacterial ubiquitin-like proteins https://www.biorxiv.org/content/10.1101/2024.11.21.623966v1

Trying to be more active here and get away from that toxic other place. If you want to know what I do, check out this paper. www.pnas.org/doi/10.1073/...