Submit your abstracts before Nov 1 to be considered for a short talk! www.grc.org/the-neurosci...

Not supposed to be working, but maybe reading a thesis on the porch with Bud on a #caturday isn’t work

🧵 Why the obsession with p < 0.05 is hurting science.

Thanks for having me Ted! Great neuro there!

Meet the #MCCS25 officers! Dr. @karynfrick.bsky.social‬ is a distinguished professor at the University of Wisconsin-Milwaukee. Her lab seeks to understand how sex-steroid hormones, aging & the environment affect memory. Join us November 13 & 14. Register here: event.fourwaves.com/MCCS25/pages

Hey does anyone know where to get TTX these days? 🐡 None of our usual sources have it

📍 Register now for #MCCS25 on November 13 & 14! Join us for talks & networking with the best and brightest in molecular and cellular cognition. #Neuroskyence Check out the link for more information and to register & submit an abstract 👉 event.fourwaves.com/MCCS25/pages

Didi says hi #caturday

1/ No, you do not always need single-cell RNA-seq. Here's why bulk RNA-seq might still be the smarter move for your experiment.

Pro tips for ❄️ cryo-sectioning in the Carolinas during the summer: 1) just don’t. wait until Oct 2) if you must, avoid days with rain - may need to wait until Oct anyway 3) get a dehumidifier and a humidity monitor. Use them Need humidity <40% per cryostat instructions Thank me later

Triangle friends. If you've been to Saxapahaw you know what an amazing community has built up around the old mills. While most of the mill escaped the Chantal flooding unscathed, other neighbors were severely affected. You can donate to recovery efforts at: www.zeffy.com/en-US/donati...

Now officially out! What do CA2 neurons become in an Nr3c2 KO? We used spatial transcriptomics to find out. With @neuroerin.bsky.social and @jmw86069.bsky.social Lots in the suppl data rdcu.be/evGGh

It's here! ✨ The #ExSRRF protocol paper is out 😍. Full details for merging Expansion Microscopy with our eSRRF analysis. From cells to tissue. A partnership with @puellesv.bsky.social's lab. Lead by Dominik Kylies and @hannah-superres.bsky.social + colleagues. #ExM #eSRRF ➡️ Open link: rdcu.be/euvEw

Preliminary program out now- GRC on Neuroscience of Social Behavior- March 2026! More talks chosen from the abstracts. Mark your calendars www.grc.org/the-neurosci...

Never seen it

Chatbots — LLMs — do not know facts and are not designed to be able to accurately answer factual questions. They are designed to find and mimic patterns of words, probabilistically. When they’re “right” it’s because correct things are often written down, so those patterns are frequent. That’s all.

US senators grilled NIH director Jayanta Bhattacharya at a hearing today about how his professed support for science squares with unprecedented grant terminations at the agency and enormous cuts that have been proposed for its 2026 budget. https://go.nature.com/3FWM2wN

Love this idea! A cartoon by Sam Lau, from 2024. #NewYorkerCartoons #productivity

#truthmatters #medsky 🧪 My summary of today's Senate hearing with Jay Bhattacharya on the NIH budget. Lots of concern among Senators about aging research. Lots of dodges, non-answers and buck passing from Jay. Bipartisan support for NIH Serious questions except for posturing by Kennedy and Britt. 🧵

Very excited to see this important work out led by the talented @mictott.bsky.social @boyiguo.bsky.social @jhubiostat.bsky.social! 🧪🧬🖥️

I urge everyone to read Unbreaking’s new page on everything the govt is doing to destroy & diminish medical research funding. It’s the best thing I’ve read on this topic: @lizneeley.bsky.social & co have such done an incredible job. unbreaking.org/issues/medic...

Excellent review by @talliezee.bsky.social and Matthew T. Birnie on the neurobiological mechanisms underlying the consequences of early life adversity. Highly recommended! www.cell.com/neuron/fullt...

Does Kei know he’s in a jet bridge at SNA? ☕️

Gary lynch rocking a huge crowd talking about th 50 years of LTP @cnlm.bsky.social @serenadudette.bsky.social @ucirvine.bsky.social @mikeyassa.bsky.social 🧪🧠 #memory @franklandlab.bsky.social

Excellent article from The New York Times on steroid hormones in brain health and diseases --no paywall--. www.nytimes.com/2025/04/22/h...

Speak up! Important to register widespread opposition to transitioning NIH to funding ideologically-motivated science. If you want advancements in knowledge and eventual cures, it is critical that research is steered by knowledgeable scientists, not political appointees

Breaking news: Jayanta “Jay” Bhattacharya, the new director of the NIH, told biomedical researchers in his first public remarks today that he’s pushing to “restore regular order” to the agency after funding cuts and delays, firings, and leadership purges. scim.ag/42pW6XP

Hot off the science presses! The largest map of the brain's wiring and activity to date is featured on the cover of @nature.com. 🧠📈 Check out 'Cortex in Context' at: www.nature.com/immersive/d4...

How does the brain work? Scientists are closer to the answer with the largest wiring diagram and functional map of a mammalian brain to date. 🧵 🧠📈

I'm looking for a new full-time research assistant ("junior specialist"). It's not quite "lab manager" because I have someone who takes care of the administrative tasks, and here I'm looking for someone to help us get research done! Info is below, please pass on to any talented candidates, thanks!

Other than markets collapsing, this week was...some kind of good news? Signs of life - and collective action - at universities and law firms. A rundown, and a reminder to go to Saturday's Day of Action: samwang.substack.com/p/a-national...

@cnn.com @nytimes.com @nbcnews.com @cbsnews.com @npr.org @abcnews4.com There are large, #HandsOff protests all over the country today to protest the fall of democracy in this country. This is really front page news and needs to be covered live. Thanks in advance for helping.

Open-Rank Faculty Cluster Hire in Depression Research Exciting opportunity at UCI in the department of Biomedical Engineering! We're seeking an innovative Assistant or Tenured Associate Professor to pioneer novel approaches in phenotyping and treatment of depression. recruit.ap.uci.edu/JPF09510

Someone just referred to Teams as "Dollar Store Zoom" and I've not agreed with something so hard in a very long time.

A lot going on here, but at least our geese laugh at attempts to RIF

How does one go in five years from running—under very difficult circumstances— a poorly designed study of infection rates, to presiding over the wholesale destruction of US biomedical research?

Collecting my thoughts at the end of one of the worst days of my life... At NIH, > 1300 people were RIFed. These range all across the board from institute directors to low level administrative staff. Communication staff and procurement appear to be hardest hit as anticipated from the HHS plan 1/n

My heart goes out to all of the good folks within NIH who are dealing with shit more directly. I am so sorry that you, your colleagues, and the institution that you love are being treated with such disrespect. 4/n

“The general public thinks that if you’re a college professor, you get paid by the school,” says Zoe McElligott, who studies neural circuits at a state university. But for 'soft money' faculty members, that’s not the case. https://go.nature.com/4jcrDSA

"How are memories formed and stored in the brain?...Long-term memory acquisition was found to be associated with a selective increase in multisynaptic boutons..". Groundbreaking new study from my friend and colleague Anton Maximov's lab: www.science.org/doi/10.1126/... Bonus: My son Luca's first pub

In today’s episode, we speak with a former director of the NIH about the institutes’ future in the face of government cuts. Listen here 🎧: pod.link/73329284/epi...

I was delighted to have an editorial in my hometown paper on the administration's threat to the NIH and what it means for the health and welfare of my peeps. For the good it may do, I urge you to also write one @sciencehomecoming.bsky.social Bonus: It's cathartic to write a scream into the void.

Still, while thrilled our 2 TTIs and 3 staff scientists were rescued, many other great scientists were terminated, incl lab and core staff

I’ll take some geology humor about now

Pls share AMAZING opportunities! Studying Depression? its biology? UCI’s new Depression Res Ctr is hiring 1) Preclinical Models: systems mechanisms of vulnerability, resilience 2) Child Adolescent, Adult Depression 3) Biomed Engineer Deep Phenotype, Intervention recruit.ap.uci.edu/JPF09510 508, 507

#ScienceJobs 🧪🧠

Expansion microscopy (ExM) of the entire mouse body (pubs.acs.org/doi/10.1021/...), developed by the labs of Profs. Jae-Byum Chang and Young-Gyu Yoon (former SynthNeuro postdocs running labs at KAIST), could empower studies of how multiple systems (nervous, immune, etc.) interact across scales.

UAB Neurobiology is hiring up to 4 new tenure-track faculty as part of 3 new open-rank searches. Come join our vibrant, supportive, and growing neuroscience community! uab.peopleadmin.com/postings/23916 uab.peopleadmin.com/postings/23944 uab.peopleadmin.com/postings/24010

New paper out in Cell Reports! Led by @susieyufeng.bsky.social, we found that chronic epilepsy in mice drives distinct synchronization deficits in hippocampus and MEC, with early changes in HPC and late-onset changes in MEC that align with progressive memory impairment. www.cell.com/cell-reports...

@drkingothebeach.bsky.social @tollkuhn.bsky.social @michaelhendricks.bsky.social @docbecca.bsky.social @dattalab.bsky.social @janaklab.bsky.social @neurocircuits.bsky.social @nicolagrissom.bsky.social @hushulab.bsky.social @meeksandmilds.bsky.social @mattsmear.bsky.social @nanopharmnc.bsky.social