During the COVID-19 pandemic, variable proportions of agency nurses and higher nurse turnover in pediatric intensive care units were associated with increased complications and ventilator-associated pneumonia. #CCR25 #MedSky ja.ma/4jI7YK2

PROMIZING Discover the impact of Proportional-Assist Ventilation vs. Pressure-Support Ventilation on extubation times in critically ill patients.

In the PROMIZING trial, proportional-assist ventilation with load-adjustable gain factors did not differ significantly from pressure-support ventilation with respect to the time to liberation from mechanical ventilation. Full trial results: nej.md/4kC2a67 @criticalcarereviews.com #CCR25

Presented at #CCR25: A trial involving children with severe acute malnutrition and gastroenteritis showed no evidence of a difference in mortality at 96 hours between oral and intravenous rehydration strategies. Full GASTROSAM trial results: nej.md/3TjfSP7 @criticalcarereviews.com

Fantastic presentation of the #GASTROSAM trial at #CCR25 - IV rehydration strategies for children with severe acute malnutrition & gastroenteritis. Amazing commitment to generating evidence in the hardest of circumstances incl a coup and flooding. Bravo! www.nejm.org/doi/full/10....

👑Live from #CCR25 the #Princetrial 🫀Does remote ischemic preconditioning reduce troponin levels after surgery? A preview on the matter is in #signavitae 🔗 www.signavitae.com/articles/10.22514/sv.2024.151 @giovannilandoni.bsky.social @mmarmiere.bsky.social

#PROMIZINGtrial results are in - no difference in time to successful liberation from mechanical ventilation between proportional-assist ventilation and pressure support ventilation #CCR25

Myburgh is going deep on the origin of balanced fluid. Debate continues 200 yrs later. LR was discovered by accident when tap water containing calcium was accidentally used in a lab experiment, causing greater muscle contractility. -Dr Myburgh #CCR25

how to quickly set up a useful MedSky account! 🦋 Mix of basic & more advanced stuff (eg designing user-curated hashtag feeds) 🦋 Take a look & add any useful tips you have in the comments section blog: emcrit.org/pulmcrit/blu... #MedSky

🩸#ANHtrial results are live #CCR25 A survey from the authors: www.signavitae.com/articles/10.22514/sv.2025.076

Conservative oxygen therapy with a target SpO2 of 90% did not reduce 90-day all-cause mortality compared to usual oxygen therapy in mechanically ventilated adult patients. #CCR25 @criticalcarereviews.com https://ja.ma/4kOIA6w

Last trial of day 2 Crystalloid FLUID Choices for Resuscitation of Hospital Patients Always a hot topic! #CCR25

Presented at #CCR25: In the ANH phase 3 trial involving adult patients undergoing elective cardiac surgery, acute normovolemic hemodilution did not reduce the number of patients receiving allogeneic red-cell transfusion. Full trial results: nej.md/3FxdMrW @criticalcarereviews.com

ICU-acquired weakness and cardiogenic shock in patients requiring mechanical support, highlighting biomarkers and outcomes. @criticalcarereviews.com #FOAMed #POCUS #FOAMcc #CCR25 https://criticalcarenorthampton.com/2025/06/12/biomarkers-in-icu-acquired-weakness/

A big moment for Royal Papworth Hospital Clinical Trials Unit ! The first RPH trial to be presented at the Critical Care Reviews Conference - Andy Klein CI of the NOTACS Trial presented the results today 👏👏 @criticalcarereviews.com @royalpapworth.bsky.social #CCR25 #NOTACS #NOTACSTrial

Andrew Klein highlights the value of working with patient and family members throughout the lifecycle of a clinical trial #NOTACStrial #CCR25

Never fails to impress every year… the venue and the conference! 😄👏@criticalcarereviews.com #CCR25

Editorial: The UK-ROX trial demonstrates that targeting lower oxygen saturation in critically ill patients is safe but does not improve outcomes. #CCR25 @criticalcarereviews.com https://ja.ma/4ngdtmn

Conservative oxygen therapy with a target SpO2 of 90% did not reduce 90-day all-cause mortality compared to usual oxygen therapy in mechanically ventilated adult patients. #CCR25 @criticalcarereviews.com https://ja.ma/4kG5gWK

A multifaceted anemia prevention and treatment bundle improved hemoglobin recovery up to 3 months after hospital discharge compared to standard care in critically ill adults. #CCR25 #MedSky ja.ma/4kGGw0I

Intravenous hydrocortisone was associated with a reduced need for new kidney replacement therapy in patients with septic shock. #CCR25 #MedSky ja.ma/3SLC3xg

Augmenting enteral protein did not improve outcomes for critically ill patients compared with standard protein levels in the intensive care setting. #CCR25 @criticalcarereviews.com https://ja.ma/4kuYRxv

Slightly late, and to be updated with the results of today's TTM2 biomarker results, today's Paper of the Day is: Biomarkers for neuroprognostication after out-of-hospital cardiac arrest https://criticalcarereviews.com/latest-evidence/paper-of-the-day

Augmenting enteral protein did not improve outcomes for critically ill patients compared with standard protein levels in the intensive care setting. #CCR25 @criticalcarereviews.com https://ja.ma/4mUjFQr

Here we go… #UKROXtrial #CCR25

Polypill, Polypill, where art thou Polypill? www.bmj.com/content/388/...

😁😁 www.bbc.co.uk/news/article...

So true www.theguardian.com/uk-news/vide...

From landslide to loveless - has the public turned on the Labour government? In the latest episode of New Economics Podcast, we discuss with @graceblakeley.bsky.social and @davidedgerton.bsky.social about whether the government is delivering on its promises. neweconomics.org/2025/02/is-t...

neweconomics.org/2025/02/why-... So good I listened to it twice! Great explanations from ⁦‪@AyeishaTS‬⁩ ⁦‪@DominicCaddick‬⁩ Seb Mang… and directly related to health policy… 👏 ⁦‪@NEF‬⁩

Every system delivers the results that it is built to do. (Whether intentional or not). @mancunianmedic.bsky.social in this month’s @bmj.com on how the hospital overcrowding we see today is an inevitable consequence of the actions we (or rather, our politicians) have taken over the last few years.

In an NHS ward I saw how Britain relies on immigrants. Yet still we tell them they’re not wanted John Harris www.theguardian.com/commentisfre...

ICU Pharmacology Secrets: Dexmedetomidine (D) (Precedex in 🇺🇸) is one of my favorite ICU drugs. It is a highly selective α-2 adrenoreceptor agonist, w sedative/analgesic/ anxiolytic properties & minimal resp depression. Its main side effects are hypotension & bradycardia

John Geddes: early pioneer and advocate of rapid pre-hospital defibrillation www.bmj.com/content/388/...

The 10th presentation at #CCR25 is RESCUE 3 Temporary Transvenous Diaphragm Pacing vs Standard of Care for Weaning From Mechanical Ventilation Register via the QR code or on the CCR website Critical Care Reviews Meeting 2025 The Best Critical Care Trials in the World

Ventilator-Associated Pneumonia After Cardiac Arrest and Prevention Strategies CCR Journal Watch criticalcarereviews.com/latest-evide... Get the latest critical care literature every weekend via the CCR Newsletter - subscribe at criticalcarereviews.com/newsletters/...

Rachel Reeves vs the markets📈📉 This week on Political Fix, we ask who’s in charge here: the Chancellor or the bond vigilantes? Plus we examine how Kemi Badenoch & Ed Davey have kicked off 2025 @robertshrimsley.bsky.social, @stephenkb.bsky.social & @katie0martin.bsky.social are on the pod 📻🎧

Excellent episode 👍 #bbcnewscast @maxi-macki.bsky.social @sanakb.bsky.social podcasts.apple.com/gb/podcast/n...

Right ventricular Injury in VV #ECMO 🔍 scoping review 📚 30 studies reported on RVI 📚 23 studies on (heterogeneous) definition 📚 13 studies reported on management, including VP & VA ECMO, positive inotropes, pulmonary vasodilators, ultra-lung-protective MV, PEEP optimization 🔗 bit.ly/4fT9MxG

This JAMA Clinical Guidelines Synopsis summarizes the 2024 Society of Critical Care Medicine guidelines on use of corticosteroids in sepsis, acute respiratory distress syndrome, and community-acquired pneumonia. ja.ma/42bw8Y2

In the news section of the @bmj.com it’s good to see that Martha’s Rule is doing some of what it’s supposed to do. If you are worried about someone in hospital and feel you’re not being listened to, you can seek a second opinion. But how many hospitals are signed up? #MedSky #PatientSafety

Pretty crisp out there this morning

Today's Paper of the Day is mechanical support in early cardiogenic shock: what is the role of intra-aortic balloon counterpulsation criticalcarereviews.com/latest-evide... Join us to read 1 paper per day and stay up-to-date as we cover the spectrum of critical care across 2025

Thousands of miles of footpaths could now be saved after the UK government committed to lifting a deadline for all rights of ways in England to be mapped. There are estimated to be more than 40,000 miles of rights of way in England which are not officially recorded. www.bbc.com/news/article...

A nice quirky story but also one that illustrates just how much the extremely wealthy could do for the public sphere if they had any real interest in it.

Absolutely brilliant 😁 @bbcradio4.bsky.social www.bbc.co.uk/sounds/play/...

Today in Focus @theguardian.com : thoughtful and balanced as always 👏 from @helenpidd.bsky.social & @samfr.bsky.social (DoI: late 80s/early 90s product of a non-fee paying Northern Irish grammar school) podcasts.apple.com/gb/podcast/t...

Excellent podcast from Michael Safi and @jamesrball.com - Today in Focus @theguardian.com podcasts.apple.com/gb/podcast/t...