NO P-VALUES! Ridiculous.

Yeah, this wouldn't work.

Morning ranting: As medicine advances, primary care has to consume a smaller portion of the pie. If you are into this sort of thing; make the metric, a portion of clinician spend. NOT total spend, that would be absurd.

If the cavs trade harden back to okc; would someone fall down every possession to the lightest 💨?

Hartenstein should have 26 fouls.

-food is both too expensive and still doesn't cost what it should because we devalue the labor involved at every step -yes, obviously, it should be more expensive to order a prepared food item delivered to your door than to buy ingredients and make that item from scratch -semi-homemade is fine too

1. Number of stories about Trump buying and selling hundreds of millions of dollars in stocks in the first three months of 2026: CBS: 0 CNN: 0 Fox News: 0 NPR: 0 PBS: 0 Politico: 0 Semafor: 0 Business Insider: 0

The parallels between Tottenham Hotspur and the Duchy of Parma and Piacenza are growing too loud to ignore - especially as the former faces the rather Napoleonic threat of relegation. in this essay I will

bad

I have no opinions on Carvana as a business, but if they somehow manage to destroy car dealerships, they will have done more good for this country than most institutions could ever dream of.

This is dynamite coaching; that dude is ridiculously good at defense. sports.yahoo.com/articles/cav...

Duran is currently allowed to just push people. Tough to beat that.

Fish oil and heart disease (from Late colleague George Fodor who lived to take down such BS) pubmed.ncbi.nlm.nih.gov/25064579/

Richard provided the gold standard for evidence appraisal for many, many years in his BMJ blog. It was thoughtful, witty, and fun.

Holier than thou; academic content is awful.

The mission vs margin piece in AAMC was interesting, but history says that if the margins of an operation are the thinned out, then only one mission will be invariably prioritized : staying alive or stated in other terms chasing the volume & the margin.

Everything wrong with meta-analysis.

Robert Kennedy Jr.’s anti-vax FDA leaders have been forced out: - Commissioner Marty Makary - CBER Director Vinay Prasad - CDER Director Tracy Beth Høeg All out.

Top Drug Regulator Is Fired From the F.D.A. www.nytimes.com/2026/05/15/u...

10x too serious

One of those things I couldn't talk about? I can now talk about.

Absolutely do this. It was the *only* good thing about mastodon.

Spirit was amazing if you expected absolutely nothing.

I think academics would have recognised this when I was doing my doctorate around 20 years ago.

wow — the preprint host, arxiv, is banning authors for a year if they submit papers with hallucinated citations 🤖

Old news but news! www.nature.com/articles/d41... #Ensiltrevir is a much better drug than #Paxlovid for #COVID in *every* single aspect: higher antiviral activity, longer half life, fewer drug - drug interactions and better clinical data (remember #Paxlovid failed their prophylaxis trials).

🎯

Important to note that the comparator is dulaglutide.

My colleague and a local patient in the news Is Advagraf the same as generic? www.ctvnews.ca/ottawa/artic... Meanwhile the ODB website considers Advagraf interchangeable with sandoz-tacrolimus XR (see pics:)

Just your friendly reminder to forget that NNT/H/V's exist. You are welcome in advance.

oh yeah- that data was certainly missing at random. 😉

Mildy PCR positive for the hantavirus, reminds me of mildly pregnant ....

1/ Update on what we know about the evolving hantavirus situation, strap in. A Swiss man linked to the ship has now tested positive after developing symptoms after disembarking. He received an exposure alert, sought care, and tested positive. This means there are 3 deaths and 5 suspected.

Anyone know why we started to believe that naltrexone was useful in EtOH use disorder? **Ignore the small trial noise; this is just blah. #medsky

Kept track of 91% of both groups @10 years!\ Partial meniscectomy for degen medial meniscal tears w/out radiograph OA doesn't work and probably makes things worse. www.nejm.org/doi/full/10....

If you're surprised that more than 70% of Polymarket users lose money, please see me after class.

This robot installs 80 panels/hour. One every 45 sec. 1,920/day ≈ 0.0008 GW/day per line. Sounds small. It’s not. Scale this across thousands of lines and #solar becomes manufacturing, not construction. 👉 10,000 lines = 8 GW/day. That’s HOW China is winning the energy game.

If this is legit then all the energy modelling, scenarios and projections you have seen are wrong. electrek.co/2026/04/27/c...

Using acronyms in an infographic is laughably out-of-touch.

This paper was retracted from the @nejm.org because the images of bronchial branching after smoke inhalation were obviously and transparently manipulated by generative AI. Look at the ruler. I don't even know what lesson to draw from this. www.nejm.org/doi/10.1056/...

I was thinking how much medicine needed a pay to participate social media platform.

Eli Lilly: Yes we know it works hence our multiple SUD RCT trials

Selecting an effect size for power analysis is hard. Many researchers fall back on Cohen's thresholds, but they have no empirical basis and vary wildly by field. Our new paper offers a better option: field-specific effect size distributions built from meta-analytic data doi.org/10.3758/s134...

My quick read of Callais decision is that the majority says if a racial community votes consistently with a party, then it is okay to deny them representation because that's just partisan gerrymandering

We need less words, better words and words spoken for the right reason.

The "fraud is thankfully rare" era is clearly over. Jack's work (et al) is incredibly timely and important. If you review trials, please consider attending or otherwise learning more about INSPECT-SR.

WOW: The UAE’s decision to quit OPEC looks like one of the biggest crude producers joining the “peak oil demand” camp. Here’s why: 🧵

Going through Altman's old statistics notes. This one is brilliant. It clearly shows why testing in low likelihood situations leads to so many false positives. The thing that is striking is how brief these are. i.e. you don't need lots of words; just the right ones. www.bmj.com/content/309/...

A ?final thread about our new study measuring financial incentives to treat different racial/ethnic groups. Today’s topic: how this paper came about. I hope the details are helpful for early-career researchers. (1/n) jamanetwork.com/journals/jam...