Jeffrey Epstein said that Trump “knew about the girls.” But what did he really mean?

We need a vaccine; ebv is so terrible.

new meme

This comment shows how totally foolish that Cochrane review actually is www.cochranelibrary.com/cdsr/doi/10.... (And contrast with the @jaccjournals.bsky.social SR www.jacc.org/doi/10.1016/...)

wow

Visualize your data.

"President Donald Trump’s federal law enforcement crackdown has hit a disgusting new low, after federal agents reportedly pepper-sprayed a 1-year-old in Chicago and then lied about it."

Maybe door dash hired some of the laid of stats folks?

#nephsky Organ donation and subsequent hydroceles

🎯

"Scared of Charlotte" is a whole new level of "scared of cities" that I'd never even considered possible

This a big deal: "China’s carbon dioxide emissions have been flat or falling for 18 months" China's economy has grown by ~5% in the last year, so this comprehensively debunks the idea (again) that emissions are tied to growth. So yes, faster progress needed, but this is how you turn the corner.

This is an amazing read and provides justification for open data.

My knees just broke.

Diagnosis of ALS is often delayed beyond what it should be. Remember, it is a motor neuron disease. If you are worried-find the sub-specialist.

This study is pretty unique. 1. The effect size is large for cvd outcomes in a super high ris population. 2. Counters previous narratives 3. More data unlikely to impact any meta-analytic findings The interpretation really comes down to only one thing: whether you think the data are reliable.

There is nearly ~0 recognition of how much employers pay for health insurance. If people understood this, our system would change.

Great piece on the FDA and menopause hormone therapy in @motherjones.com it is the most medically accurate coverage I have read from the press! www.motherjones.com/politics/202...

This is one of the most remarkable academic debacles I've ever seen. A large RCT got published in BMJ. There are currently 44 Pubpeer comments, mostly about the data, including...well. Read for yourself. pubpeer.com/publications...

My son Seamus died 15 years ago today. He was killed by a careless driver in a crosswalk. He walked at 9 months, almost as if he knew he wouldn’t have much time. His favorite thing to do was throw rocks into water. He loved the moon. He called butterflies “buddy buddies.” I miss him every day.

As the ~discourse~ seems to bend interminably towards Republicans trying to figure out how they can (further) HDHP-ify ACA coverage, it's worth revisiting what is probably our best (most rigorous) study on the effect of deductibles in health insurance. academic.oup.com/qje/article-...

This is just an amazing story. LSU's initial offer was <1/2 what he was contractually owed. www.espn.com/college-foot...

The editorial of this paper is kind of funny. They don't recommend use given "outsized results of early trials have failed to be replicated". Given the effect size is ginormous, the likelihood that any meta-analysis would not show that this is beneficial is very small. www.nejm.org/doi/full/10....

We invented the most powerful weight loss drug ever and it might be an effective oncology drug too 😳🤯 "Low-dose RETA significantly reduced tumor volume by 3-fold compared to vehicle, demonstrating efficacy comparable to anti-PD-1 therapy, which achieved a 5-fold reduction in tumor volume"

bahahahahahahhahahahahahha. MORE RESEARCH LIKE THIS!

When a man's livelihood depends on finding a spurious correlation. . .

If someone constantly needs to tell you how good they are, they aren't that good.

The currents drugs are going to get cheaper b/c they are 2nd generation. 3rd generation drugs are approaching quickly. Who even knows how many generations there will be in the next 10 years.

cc: @ianbetteridge.com

Pro tip: understand the small data before going to the big data regression mess.

I appreciate @bmj.com follows a formal process, but just how much evidence do they need before adding an Expression of Concern. Numerous PubPeer comments for stem cell for heart disease paper - which had huge media attention hailing it as a medical breakthrough. pubpeer.com/publications...

Dumb statistical choices tend to beget dumb statistical choices.

This is, unsurprisingly, nonsensical. Is he suggesting eliminating health insurance and giving people a few thousand dollars instead? And then when they get a cancer diagnosis they just go bankrupt? He is so unserious. That's why we are shut down and Americans know it.

Seems like a good time to do a special issue of @jhppl.bsky.social on the Politics of Private Health Insurance. Call for papers will be out soon, so stay tuned. There’s seem to be, uh, a few politically relevant topics to discuss. @mirandayaver.bsky.social @adrianna.bsky.social

Senate update: Republicans are now trying to sneak a backdoor national abortion ban into their government funding bill. Republicans will stop at nothing to control women's health care decisions.

Affordability week coming to a close.

initially thought that this was a shadow being projected on his face. didn’t realize he was in blackface

Heterogeneity of effect size! The RRR is consistent in all these ascvd preventive treatments.

Naming things is important

I feel like psychometrics is uniquely bad at naming things. Parallel, congeneric, tau-equivalent, essentially tau-equivalent measures? Configural, metric, scalar, residual invariance? Item difficulty defined so that the higher the difficulty, the easier the item???

Look I’m just a local idiot, but from where I stand this is the worst set of political maneuvers I’ve ever seen grown adults make.

LET ME BE PERFECTLY CLEAR: DOJ DID ALL OF THIS TO TRY AND STOP PAYMENTS TO PEOPLE UNDER AN ANTI-HUNGER PROGRAM.

And @brendonneuen.bsky.social with another simultaneous pub in @jama.com jamanetwork.com/journals/jam... Flozination by GFR/albuminuria #KidneyWk

What on Earth is this? This is a double blinded RCT of high risk HD patients in Canada and Australia at numerous sights. The pre-test probability is low. However, the results are stunning with CI's that don't broach 1. Everything got better, stroke, MI, vascular, and point estimate of all cause.

🔥

I can confirm this take is true.

Hundreds of thousands of people, dead because of a decision made by the world's richest man