Jesse Brown
@jesseab.bsky.social
š¤ 316
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Neuro + data scientist, building radiata.ai - better brain biomarkers.
reposted by
Jesse Brown
Bratislav Misic
10 days ago
Network spreading and local biological vulnerability in amyotrophic lateral sclerosis |
doi.org/10.1038/s420...
How do brain network structure and local biological features shape the spatial patterning of atrophy in ALS?
@asafarahani.bsky.social
investigates ⤵ļø
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Stimulating the LGN with ultrasound and real-time fMRI, this is cool. Ultrasound system for precise neuromodulation of human deep brain circuits.
www.nature.com/articles/s41...
10 days ago
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Jesse Brown
Brad Postle
16 days ago
The Dept. of Psychology at the U. WisconsināMadison has an opening for an Assistant Professor in the area of Computational Neuroscience and/or Cognitive Science, with an emphasis on artificial intelligence (AI). Domain of behavior or cognition is open. Details at
jobs.wisc.edu/jobs/assista...
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Assistant Professor of Psychology - Madison, Wisconsin, United States
Current Employees: If you are currently employed at any of the Universities of Wisconsin, log in to Workday to apply through the internal application process.Job Category:FacultyEmployment Type:Regula...
https://jobs.wisc.edu/jobs/assistant-professor-of-psychology-madison-wisconsin-united-states-7d9076ee-f28e-4bab-951f-7d3e5e4b2b35
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Would be perfectly happy if cool new mechanistic brain function studies like this one omitted the individual trait prediction. Don't think every new finding needs a cognitive correlation to have merit.
www.nature.com/articles/s41...
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Large-scale cortical functional networks are organized in structured cycles - Nature Neuroscience
The human brain cycles through a repertoire of brain networks on a 1-second timescale during rest and tasks. This cycling appears to allow periodic engagement of essential cognitive functions, with th...
https://www.nature.com/articles/s41593-025-02052-8
17 days ago
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Jesse Brown
Ben Hayden
22 days ago
Sad day for peope who still believe brain areas are the primary organizational units of function in the brain.
www.nature.com/articles/s41...
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A brain-wide map of neural activity during complex behaviour - Nature
The International Brain Laboratory presents a brain-wide electrophysiological map obtained from pooling data from 12 laboratories that performed the same standardized perceptual decision-making task i...
https://www.nature.com/articles/s41586-025-09235-0
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Doing a deep dive on TMS. Kinda crazy how much of this field is built on DLPFC-sgACC anticorrelation. One little edge.
about 1 month ago
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Jesse Brown
Lucina Uddin
4 months ago
When I first started working with resting state fMRI as a postdoc, there was a lot of skepticism about what we could learn from it. 20 years later, it's hard to imagine where the field of neuroscience would be without it. Here's a summary š§
www.nature.com/articles/s41...
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The history and future of resting-state functional magnetic resonance imaging - Nature
This Review provides an overview of the history of resting-state functional MRI research, which has helped to reveal the spatiotemporal organization of the brain, and discusses how it can contribute f...
https://www.nature.com/articles/s41586-025-08953-9
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reposted by
Jesse Brown
Eric Topol
5 months ago
Using the advances in the science of aging to prevent the major age-related diseases (no reversal of aging required)
www.theguardian.com/world/2025/m...
@theguardian.com
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āGet rid of the pseudoscienceā: top doctorās plan to improve Americaās health
Eric Topol says we can prevent age-related disease and live fuller lives ā but only if we reject anti-science āmalarkeyā
https://www.theguardian.com/world/2025/may/08/eric-topol-health-book
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reposted by
Jesse Brown
Jean-RƩmi King
5 months ago
š“ Our `Brain and AI` team at Meta has a new Research Engineer position in Paris to work on infrastructure and scale deep learning experimentations:
www.metacareers.com/jobs/1769841...
We'll favor industry experience or Github track record.
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https://www.metacareers.com/jobs/1769841..
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reposted by
Jesse Brown
The Transmitter
5 months ago
The scientific community needs to develop processes to support, hire and retain researchers whose work sits between traditional fields of study, writes
@avramholmes.bsky.social
#neuroskyence
www.thetransmitter.org/future-of-fm...
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fMRI must break out of its silo
We need to develop research programs that link phenomena across levels, from genes and molecules to cells, circuits, networks and behavior.
https://www.thetransmitter.org/future-of-fmri/to-make-a-meaningful-contribution-to-neuroscience-fmri-must-break-out-of-its-silo/?utm_source=bluesky&utm_medium=org-social&utm_campaign=20250416-rp-fMRI-break-silo
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reposted by
Jesse Brown
Eric Topol
5 months ago
Most people havenāt heard of this test, which is available in the US. It accurately predicts Alzheimerās (not just if thereās a risk, but when). It is modulated by exercise and likely other lifestyle factors. Hereās (almost) everything we know about it
erictopol.substack.com/p/the-breakt...
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reposted by
Jesse Brown
Sam Krimmel
6 months ago
It's shocking how little is known about the brainstem red nucleus. In our new paper āThe human brainstemās red nucleus was upgraded to support goal-directed actionā out now in
@naturecomms.bsky.social
we show that current thinking on the red nucleus is in need of a serious upgrade.
rdcu.be/ehbOy
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reposted by
Jesse Brown
Lianglong Sun
6 months ago
Happy to share that our article āHuman lifespan changes in the brainās functional connectomeā is now published online at Nature Neuroscience
@natureneuro.bsky.social
! Many thanks to all collaborators & data contributors, and the editor team & reviewers!
www.nature.com/articles/s41...
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Human lifespan changes in the brainās functional connectome - Nature Neuroscience
Sun et al. report human lifespan changes in the brainās functional connectome in 33,250 individuals, which highlights critical growth milestones and distinct maturation patterns and offers a normative...
https://www.nature.com/articles/s41593-025-01907-4
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reposted by
Jesse Brown
Carolyn Fredericks
6 months ago
We are HIRING!! Postdoc for multimodal imaging lab at Yale. If you get excited about preclinical and prodromal states, atypical Alzheimerās, graph theory, predictive modeling, and/or baked goods at lab meetings, come join us:
postdocs.yale.edu/postdoctoral...
Please share with your circles!
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Proxies aren't the thing, the thing is the thing. Just don't forget what the "thing" is.
6 months ago
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reposted by
Jesse Brown
Frederic Schaper
6 months ago
Is generalized epilepsy a seizure of the whole brain or a specific brain network? In our new paper out now in
@naturecomms.bsky.social
, we investigate this by combining brain abnormalities and DBS with the human connectome. Paper:
nature.com/articles/s41...
A š§µ below:
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A generalized epilepsy network derived from brain abnormalities and deep brain stimulation - Nature Communications
Ji et al. identify an idiopathic generalised epilepsy network that links heterogeneously distributed brain abnormalities to a common brain network and deep brain stimulation sites which reduce general...
https://nature.com/articles/s41467-025-57392-7
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Here's a new open dataset of ~4000 processed brain structural MRIs from across the lifespan:
huggingface.co/datasets/rad...
Get it in three lines of code: pip install datasets from datasets import load_dataset ds = load_dataset("radiata-ai/brain-structure", trust_remote_code=True)
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radiata-ai/brain-structure Ā· Datasets at Hugging Face
Weāre on a journey to advance and democratize artificial intelligence through open source and open science.
https://huggingface.co/datasets/radiata-ai/brain-structure
8 months ago
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reposted by
Jesse Brown
Kevin Mitchell
8 months ago
Rethinking Brain Mechanisms in the Light of Evolution with Paul Cisek
youtu.be/CnT7jaQX4X8?...
- if you want to understand what brains are for (and their functional organisation), this is the way... šš
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Rethinking Brain Mechanisms in the Light of Evolution with Paul Cisek
YouTube video by Kempner Institute at Harvard University
https://youtu.be/CnT7jaQX4X8?si=N1xlAMY7dy6pqOC1
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reposted by
Jesse Brown
Nature Neuroscience
8 months ago
Using a brainācomputer interface to challenge monkeys to override their natural time courses of neural activity reveals that the time courses are highly robust, suggestive of network-level computational mechanisms
@aaronbatista.bsky.social
and colleagues
www.nature.com/articles/s41...
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Dynamical constraints on neural population activity - Nature Neuroscience
Oby, Degenhart, Grigsby and colleagues used a brainācomputer interface to challenge monkeys to override their natural time courses of neural activity. They found the time courses to be highly robust, ...
https://www.nature.com/articles/s41593-024-01845-7
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Here's how you can build classifiers for brain structural MRI data on
radiata.ai
.
www.youtube.com/watch?v=oDan...
We built this to make it easier to: - set up and run machine learning models on the fly with no installs
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Radiata Brain Imaging Classification
YouTube video by Radiata
https://www.youtube.com/watch?v=oDansLudwc4
9 months ago
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Pretty amazing that we can now do regression with words and concepts (via LLM embeddings) as predictors.
arxiv.org/abs/2411.14708
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Understanding LLM Embeddings for Regression
With the rise of large language models (LLMs) for flexibly processing information as strings, a natural application is regression, specifically by preprocessing string representations into LLM embeddi...
https://arxiv.org/abs/2411.14708
10 months ago
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Our brain biomarker engine is live at
radiata.ai
. Here's how you can use our interactive latent space to explore brain anatomy individual differences in structural MRI scans.
www.youtube.com/watch?v=EaJy...
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Radiata Brain Latent Space
YouTube video by Radiata
https://www.youtube.com/watch?v=EaJyo9b2W4M
10 months ago
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Enjoying this, giving me 1996 feels and hope for the next wave.
over 1 year ago
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Optimal approaches to analyzing functional MRI data in glioma patients
www.sciencedirect.com/science/arti...
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Optimal approaches to analyzing functional MRI data in glioma patients
Resting-state fMRI is increasingly used to study the effects of gliomas on the functional organization of the brain. A variety of preprocessing techniā¦
https://www.sciencedirect.com/science/article/pii/S0165027023002303
almost 2 years ago
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