Today we are hosting Dr Barbara Slusher from John’s Hopkins speaking about her drug discovery research programs - amazing scientist and a full house for her seminar !

This made me happy. And happy new year!

It’s buzzing like the first day of school!!!

How did we get to a place where lower-case ‘l’ is an acceptable symbol for liter/litre?

So much for another relic from my childhood: cordcuttersnews.com/mtv-is-shutt...

Online now! Discovery of a tau-aggregate clearing compound that covalently targets P4HB #chembiol

MOFs are pretty darn cool. Here's our story, in @cenmag.bsky.social cen.acs.org/people/nobel...

Our new PNAS paper "Enhanced PIEZO1 function contributes to the pathogenesis of sickle cell disease" is out: www.pnas.org/doi/10.1073/... 1/3

Scientists believe factors like diet and chemical exposure could play a role in a condition largely driven by genetics www.statnews.com/2025/10/03/n...

Ice freshly ejected from Enceladus contains complex organics Reanalyzing data from Cassini's 2008 flyby reveals new, complex organic molecules in the spray from Saturn’s icy moon. cen.acs.org/physical-che... #chemsky 🧪

This October I’m drawing one molecule a day inspired by proteins in pdb @rcsbpdb.bsky.social Day 2/31 Prompt WEAVE N-terminal domain of a Fibrion - a building block of silk fiber produced by silkworms. Pdb: 3UA0 Next prompt is CROWN and I would love your suggestions!

As a little boy, my grandparents gave me this book. This story of Pasteur is the one that made me want to be a scientist. And it doesn’t even mention optical activity!!

Who will win the #ChemNobel? cen.acs.org/people/nobel... #chemsky 🧪

As a little boy, my grandparents gave me this book. This story of Pasteur is the one that made me want to be a scientist. And it doesn’t even mention optical activity!!

President Trump announced on Tuesday that Pfizer has agreed to offer lower prices on its drugs to the Medicaid program and directly to patients www.statnews.com/2025/09/30/t...

I rarely post about work, but in writing this email today asking how to be reimbursed for the cost of hosting a scientific visitor I wrote this explainer. This is not a complaint - but shows how we have to use our own salaries to enrich our environment and the commitment that takes

We want to congratulate our President, Dr. Tony Letai, on his appointment as Director of the NCI. This announcement marks an historic moment for cancer research. Dr. Letai has been a tireless advocate and visionary leader for functional precision medicine 🧵 www.nih.gov/news-events/...

“dad can you can get me one of those retro digital cameras?”

I missed this paper at the time but love this kind of study: "The total mass, number, and distribution of immune cells in the human body" "an average individual’s immune system consists of approximately 1.8 trillion cells, weighing around 1.2 kg" www.pnas.org/doi/10.1073/...

I rarely post about work, but in writing this email today asking how to be reimbursed for the cost of hosting a scientific visitor I wrote this explainer. This is not a complaint - but shows how we have to use our own salaries to enrich our environment and the commitment that takes

Meeting my trainee for coffee and project strategizing in the amazing NIH Clinical Center. Inspiring.

Merch!

But the poster sessions are buzzing - so much amazing NIH science on show! I got in trouble for standing on a ledge to take this photo….. you’re welcome

It’s that time of year again - NIH Research Festival !

It’s that time of year again - NIH Research Festival !

I must be doing something right - daughter raided my vinyl.

Biomedikum @ki.se

Biomedikum @ki.se

#ResearchHighlight 🚨 In a recent study, the Nussenzweig lab investigated the mechanisms underlying #cytarabine-induced neurotoxicity and provide a mechanistic explanation for the differing neurotoxicity profiles of #gemcitabine. 📖⬇️

I struggled with homesickness like this, and remember crying instantly once because there was a kangaroo on TV. It was always just beneath the surface. It took years for me to get through it. www.youtube.com/watch?v=gPXG...

I show this dedication in Volume 1 to 'Inorganic Syntheses' to the organic chemists whenever I can. Solid.

The NYC #Legionnaires outbreak has grown to 22 cases, with 1 death. Cases have been reported in Central Harlem (ZIP codes 10027, 10030, 10035, 10037 & 10039) & bordering communities. Sounds like cooling towers (multiple?) may be the source??? www.nyc.gov/site/doh/abo...

I show this dedication in Volume 1 to 'Inorganic Syntheses' to the organic chemists whenever I can. Solid.

I love getting into bed and thinking about all the things I didn’t do today

I love getting into bed and thinking about all the things I didn’t do today

As the Trump administration looks to reshape biomedicine, it is taking aim at one of the most universal ways scientists study disease and determine whether drugs are safe and may work in people: animal research. www.statnews.com/2025/07/25/n...

Proud of this new article from us in Nature, with long-term collaborators at Chicago and NCI "NNMT inhibition in cancer-associated fibroblasts restores antitumour immunity" www.nature.com/articles/s41...

Proud of this new article from us in Nature, with long-term collaborators at Chicago and NCI "NNMT inhibition in cancer-associated fibroblasts restores antitumour immunity" www.nature.com/articles/s41...

It’s take your kids to the gig night. My girls (15 and 13) seeing their first real gig tonight @dinosaurjr.com - AJ’s @snailmail.bsky.social who are giving wonderful Juliana Hatfield vibes !

Wrote about becoming one of the many ladies my age who lifts--and the raft of junk science and grifts out there for perimenopausal women who are trying to stave off muscle and bone loss as we age (gift link):

It's amazing to me that one letter f is the difference between UNFAIR and FUNFAIR

One thing that affects me reviewing: I’m no longer spending time working out how to log in to websites. Why are there separate logins for reviewers and authors? If I can’t log in easily to provide a review (ie my unpaid work) I’m work not to spend time solving that problem.

Am I the only scientist who likes to cool off in the coldroom on a hot day?

I call it “the refreshing room”

A room with lots of NMR magnets and LC/MS machines is also a good bet for strong air conditioning!

Am I the only scientist who likes to cool off in the coldroom on a hot day?

The group's research was recognized by @rnasociety.bsky.social with the Moderna Biomedical Award for Biomedical Innovation in RNA. This was a real honor and is top of mind with this year's RNA Society meeting taking place right now. I will see you all next year in Montreal!

Minervo Perez and I visited NCATS to present the group's work on covalent inhibitor discovery and got the chance to catch up with many friends, including the Matt Hall. @cispt2.bsky.social