An amazing experience to be a part of this multi-disciplinary project within the Bird Lab! 🐦✨ We brought together molecular biology🧩⛓️, genomics🧬🧶, and explainable machine learning📈🖥️🤖 to understand mechanisms of SALL4 function. So proud of this team effort! 🤝🙌 Check out the full breakdown below 🧵👇

🚨 Multiple #PhD opportunities for lab or computational applicants. Do you want to understand the molecular basis of #epigenetic dysfunction in human disease? Come work with our group at the fantastic, collaborative @uoe-igc.bsky.social in a beautiful, liveable city. 🧵 1/4 Please repost 🙏

1/5 Glad to share our latest work with Ian Chambers’ lab published @embojournal.org in which we investigated the role of TET DNA de-methylases during cell fate transitions. Great team effort, many thanks to Sara Gonzalez Brito @ebarbieri.bsky.social @edinuni-irr.bsky.social doi.org/10.1038/s443...

Integrator and Restrictor act sequentially to control transcription! Great set of experiments to complement some of the Integrator-Restrictor overlap hypotheses proposed here doi.org/10.1371/jour...

🚀 Excited to share my latest paper on using SHAP, to predict direct target genes of chromatin-associated factors! Check it out for insights into gene regulation and the power of explainable AI in genomics! #XAI #SHAP #Genomics doi.org/10.1371/jour... Let's break down what we found! 👇

Excited to share my latest preprint! 🚀 We infer regulatory relationships between chromatin-associated proteins and transcriptional control.

Very excited that our paper describing a critical role for the PNUTS-PP1 phosphatase complex in transcription pause release is up online! This was a massive team effort with @edimitrova.bsky.social and the rest of the @robklose.bsky.social lab www.cell.com/molecular-ce... A short thread: (1/8)

Looking forward to sharing a new publication from the lab tomorrow! Something a bit different from us this time around. Stay tuned….

Non-native English speakers need 50% more time to write a paper When they do, they face a 2.5 times higher chance of being rejected because of language journals.plos.org/plosbiology/...

Loved being back in Edinburgh. Such a beautiful city, such great science. Great to catch up with Adrian, @cathyabbott.bsky.social @cellysally.bsky.social @hannahlong.bsky.social @kashyapchhatbar.bsky.social @r-pantier.bsky.social et al. Thanks Cath+Adrian for the hospitality and Congrats Sara!