Marta Shahbazi
@marta-shahbazi.bsky.social
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Group leader @MRC_LMB. Cell fate decisions in the early mammalian embryo
pinned post!
I couldn’t be more proud of
@lucaschwarz.bsky.social
!! He has been awarded a Perutz Student prize for his work developing aneuploid models of the human placenta.
www2.mrc-lmb.cam.ac.uk/lmb-prizes-2...
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LMB Prizes given to students, postdocs and staff - MRC Laboratory of Molecular Biology
To mark the end of the annual LMB Symposium, the 2025 Perutz Student Prize, Joan A. Steitz Postdoc Prize and Eileen Southgate Staff Prize were awarded.
https://www2.mrc-lmb.cam.ac.uk/lmb-prizes-2025/
3 months ago
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Marta Shahbazi
Ana Tufegdzic Vidakovic
about 1 month ago
Happy to share a new preprint from our lab, uncovering "spooky action at a distance" - for RNA Polymerase II:
www.biorxiv.org/content/10.6...
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Stalling of elongating Pol II triggers Ser7 phosphorylation in trans to drive transcription recovery
DNA is scattered with obstacles that stall RNA polymerase II (Pol II) and block the production of full-length transcripts. Two mechanisms are known to resolve stalled Pol II: transcription-coupled nuc...
https://www.biorxiv.org/content/10.64898/2025.12.04.692291v1
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I felt dizzy, heartbroken and angry reading this. A must read article for anybody interested in women's health, pregnancy, and labour.
add a skeleton here at some point
about 2 months ago
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Marta Shahbazi
Francesca Cesari
2 months ago
Snake bites kill/debilitate 1000s of people annually in Sub-Saharan African. A new nanobody cocktail is shown to be highly effective against 17 of the most dangerous African snake species. Unlike other anti-venoms it also protects against venom-induced dermal necrosis🧪
www.nature.com/articles/s41...
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Nanobody-based recombinant antivenom for cobra, mamba and rinkhals bites - Nature
A recombinant antivenom composed of eight nanobodies provides broad protection against venom-induced lethality and dermonecrosis in mice challenged with venoms from cobras, mambas and rinkha...
https://www.nature.com/articles/s41586-025-09661-0
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Marta Shahbazi
MRC Laboratory of Molecular Biology
3 months ago
Congratulations to the 2025 recipients of the Perutz Student Prize and the Joan Steitz Postdoc Prize: Claudia De Miguel,
@lucaschwarz.bsky.social
, Tom Dendooven, Sofia Lövestam, Katerina Naydenva & Tomke Stürner. Find out why they won here:
www2.mrc-lmb.cam.ac.uk/lmb-prizes-2...
#LMBNews
👏
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I couldn’t be more proud of
@lucaschwarz.bsky.social
!! He has been awarded a Perutz Student prize for his work developing aneuploid models of the human placenta.
www2.mrc-lmb.cam.ac.uk/lmb-prizes-2...
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LMB Prizes given to students, postdocs and staff - MRC Laboratory of Molecular Biology
To mark the end of the annual LMB Symposium, the 2025 Perutz Student Prize, Joan A. Steitz Postdoc Prize and Eileen Southgate Staff Prize were awarded.
https://www2.mrc-lmb.cam.ac.uk/lmb-prizes-2025/
3 months ago
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Marta Shahbazi
Gurdon Institute, University of Cambridge
3 months ago
A Nobel-winning scientist of great modesty and humour, John Gurdon died on 7 Oct. Not only did he make a discovery that laid the foundations for stem cell research, he also created one of the best environments for research at the Wellcome/CRUK Gurdon Institute
wellcome.org/news/sir-joh...
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Sir John Gurdon, 1933-2025 | Wellcome
A Nobel-winning scientist of great modesty and humour, John Gurdon died on 7 October. He made a discovery that opened up the field of cloning research, and created one of the best environments for res...
https://wellcome.org/news/sir-john-gurdon-1933-2025?utm_source=linkedin&utm_medium=o-
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reposted by
Marta Shahbazi
MRC Laboratory of Molecular Biology
4 months ago
🎉 Happy Postdoc Appreciation Week! 🎉 As LMB Group Leaders
@kellythd-nguyen.bsky.social
,
@brfalcon.bsky.social
&
@marta-shahbazi.bsky.social
attest, our postdocs are at the heart of our research community and shape everything we do. Thank you postdocs!
#PostdocAppreciationWeek
#PAW25
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I could not have summarised our article better than
@katherine-brown.bsky.social
!! Please see below and keep reading if you are interested in human embryo research policy. It was such a pleasure to write this piece with Susana, Mina and Catello.
add a skeleton here at some point
4 months ago
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"With debate growing around whether the “14-day rule” on human embryo research remains fit for purpose, the need for inclusive public dialogue is more important than ever".
www.nuffieldbioethics.org/news-blog/if...
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If it’s time to revisit the 14-day rule, it’s also time to engage the public - Nuffield Council on Bioethics
Molly Gray, Public Engagement Manager at the Nuffield Council on Bioethics, introduces our upcoming public dialogue and discusses the importance of engaging the public in conversations around the 14-d...
https://www.nuffieldbioethics.org/news-blog/if-its-time-to-revisit-the-14-day-rule-its-also-time-to-engage-the-public/
5 months ago
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🤩 Very excited to share our new work! We have derived euploid and aneuploid trophoblast organoids and extra-embryonic mesoderm cell lines from early human embryos. In doing so, we have characterised the tissue requirements for their specification. If you want to know more, continue reading….
5 months ago
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I recently listened to a fantastic podcast on
@radiolab.bsky.social
about the lack of public engagement during the AIDS epidemic. Those affected felt unheard and abandoned. As scientists, we have a responsibility to engage with the public and hear their views.
7 months ago
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Very cool finding!
www.nature.com/articles/s41...
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Apical size reduction by macropinocytosis alleviates tissue crowding - Nature Communications
This study reveals that epithelial cells can reduce their apical surface area via macropinocytosis to relieve tissue crowding, offering a reversible alternative to cell extrusion and highlighting a ne...
https://www.nature.com/articles/s41467-025-60724-2
7 months ago
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Marta Shahbazi
Philip Ball
7 months ago
It's not clear what this means. So Nature Springer journals, including Nature and Scientific American, won't be available at the NIH? Is the next step to prohibit NIH staff from publishing in Nature? And you know the Nazis cancelled Nature too, right?
www.axios.com/2025/06/25/t...
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Scoop: Trump admin cuts contracts with scientific publishing giant
The administration has questioned editorial practices and whether journals are partisans in scientific debates
https://www.axios.com/2025/06/25/trump-cuts-contracts-scientific-publisher
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Beautiful!
add a skeleton here at some point
7 months ago
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Marta Shahbazi
My Anh Truong
7 months ago
Had so much fun the past few weeks playing around with human trophoblast stem cells and organoids in Cambridge! Thanks
@marta-shahbazi.bsky.social
for hosting me,
@lucaschwarz.bsky.social
for all his experimental wisdom, and everybody at
@cellbiol-mrclmb.bsky.social
for making me feel at home!
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Has April Fool’s day been moved to May???
add a skeleton here at some point
8 months ago
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reposted by
Marta Shahbazi
Young Embryologist Network
8 months ago
Luca Schwarz from
@cellbiol-mrclmb.bsky.social
presented his blastocyst-derived trophoblast organoid as an in vitro model of human placenta to investigate ExMe (extraembryonic mesenchyme)
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Busy day for our lab! If you want to know more about our placental organoid work don’t miss
@lucaschwarz.bsky.social
’s talk at
@yen-network.bsky.social
. Miguel, a postdoc from the lab, will talk about his PhD work at
@cammorphoseries.bsky.social
and I will present at
@brisunipress.bsky.social
8 months ago
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Marta Shahbazi
Alberto Elosegui-Artola
8 months ago
Impressive work by
@santoslab.bsky.social
creating a 3D model of human amnion from hESCs!
www.cell.com/cell/fulltex...
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Post-gastrulation amnioids as a stem cell-derived model of human extra-embryonic development
An embryonic stem cell-based 3D model that accurately recapitulates the size, morphology, and functional features of the human amnion at 4 weeks, termed the post-gastrulation amnioid (PGA), is develop...
https://www.cell.com/cell/fulltext/S0092-8674(25)00458-1
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A room with a view
#GRC
8 months ago
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Working hard with
@mllthingsdna.bsky.social
@katemiro.bsky.social
@ms01.bsky.social
and
@vrendo.bsky.social
@embo.org
#ChromoPloidy25
9 months ago
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If you are interested in IVF and human reproduction, don't miss this event to celebrate Bob Edwards' centenary:
www.tickettailor.com/events/churc...
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Register here – Bob Edwards centenary: His life, work and legacy
This conference to celebrate the life, work and legacy of Sir Robert Edwards (IVF pioneer) will take part in two sessions. The ...
https://www.tickettailor.com/events/churchillarchivescentre/1649990
9 months ago
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This is really cool! Linking transcriptomics and mechanics.
www.nature.com/articles/s41...
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A computational pipeline for spatial mechano-transcriptomics - Nature Methods
The authors present a computational framework that leverages mechanical force inference and spatial transcriptomics to enable analyses of the interplay between the transcriptomic and mechanical state.
https://www.nature.com/articles/s41592-025-02618-1?utm_source=nature_etoc&utm_medium=email&utm_campaign=CONR_41592_AWA1_GL_DTEC_054CI_TOC-250410&utm_content=20250410
9 months ago
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Marta Shahbazi
MRC Laboratory of Molecular Biology
9 months ago
We’re looking for a multi-skilled Fluidic Automation Bioengineer to join John O’Neill’s group in the LMB’s Cell Biology Division, to develop novel platforms for drugging the circadian clock in cultured cells and tissues over many days.
www.nature.com/naturecareer...
Closes 24 APR
#ScienceJobs
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This is fantastic! There is light at the end of the tunnel
add a skeleton here at some point
10 months ago
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Marta Shahbazi
MRC Laboratory of Molecular Biology
10 months ago
There’s still time to apply to the LMB’s Rising Talent Fellowship for Black heritage scientists. With this 3-year postdoc position we want to enable scientists of Black heritage to learn & grow their experience. Application deadline: 23 March More info:
www2.mrc-lmb.cam.ac.uk/recruitment/...
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Marta Shahbazi
Itai Yanai
10 months ago
We have to stand up for science! Anyone who can join these rallies and believes that US science must be defended should come! I’ll be there in DC - join me!
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reposted by
Marta Shahbazi
MRC Laboratory of Molecular Biology
11 months ago
From the importance of mentorship to her love of martial arts,
@kellythd-nguyen.bsky.social
, Group Leader in the LMB’s Structural Studies Division, was recently profiled as a ‘Cell scientist to watch’ by
@jcellsci.bsky.social
Full interview here:
journals.biologists.com/jcs/article/...
#LMBintheNews
add a skeleton here at some point
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Marta Shahbazi
Niakan Lab
11 months ago
Very sorry to hear of the passing of Roger Pedersen. He was an outstanding developmental and stem cell biologist & helped to establish the Cambridge Stem Cell Institute. Our thoughts are with his family.
obgyn.stanford.edu/in-the-news/...
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Roger-Pedersen-Obituary-2025
https://obgyn.stanford.edu/in-the-news/roger-pedersen-obituary-2025.html
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Marta Shahbazi
Katherine Brown
11 months ago
Big news - I'm going to be moving to a new position at The Company of Biologists, working across all our journals. This means my job is up for grabs! If you're an experienced editor with a love of developmental biology and its community, this could be the role for you. Full details in the link.
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https://www.biologists.com/wp-content/uploads/DEV_ExecEd.pdf
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Marta Shahbazi
Kevin M. Kruse
11 months ago
Whenever you hear someone sneer about scientific research that seems useless to them — “they’re studying the spit of lizards?!” — remind them that’s exactly how we got Ozempic.
globalnews.ca/news/9793403...
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How a Canadian scientist and a venomous lizard helped pave the way for Ozempic - National | Globalnews.ca
In 1984, Dr. Daniel Drucker, an endocrinologist from the University of Toronto, discovered a hormone that helped pave the way for popular diabetes drugs such as Ozempic.
https://globalnews.ca/news/9793403/ozempic-canada-scientist-venomous-lizard-weight-loss/amp/
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Marta Shahbazi
MRC Laboratory of Molecular Biology
11 months ago
Join our Structural Studies Division, leading a research group developing computational methods to address questions in molecular & cellular biology! You will be supported by core funding, excellent facilities & enthusiastic colleagues. Apply by 18 MAR
www.nature.com/naturecareer...
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Congratulations
@lara-kruger.bsky.social
Can’t wait to see the exciting science that will come from your lab
add a skeleton here at some point
11 months ago
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Marta Shahbazi
James Briscoe
11 months ago
Registration open for this year's Young Embryologist Network meeting 19 May, The Francis Crick Institute, London
thenode.biologists.com/yen-2025-con...
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YEN 2025 Conference: Registration is open! - the Node
Register now for the Young Embryologist Network meeting - Monday 19 May 2025 at the Francis Crick Institute. Are you an early career researcher in
https://thenode.biologists.com/yen-2025-conference-registration-is-open/events/
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On World Cancer Day I celebrate scientific progress, which has saved my mother’s life twice. A special thought for all of those that didn’t make it (in my heart are my grandma and my aunt).
11 months ago
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Marta Shahbazi
Cambridge Morphogenesis Seminar Series
12 months ago
Today, at 2:30 pm (UK time),
@marta-shahbazi.bsky.social
will kick off the new Cambridge Morphogenesis Seminar Series term! Her talk will be about the morphogenetic control of cellular differentiation during gastrulation. Please subscribe to our mailing list for access to the Zoom link.
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So useful for the field!
add a skeleton here at some point
12 months ago
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Marta Shahbazi
Cambridge Morphogenesis Seminar Series
12 months ago
The Cambridge Morphogenesis Seminar is back! We assembled an amazing lineup for you, kicking off the new term of the seminar series with a talk by
@marta-shahbazi.bsky.social
on the 27th of January, 2:30 pm (UK time). We are looking forward to seeing you all!
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This is a fantastic initiative! Thanks for helping mother scientists
add a skeleton here at some point
12 months ago
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Merry Christmas from the Shahbazi lab! Let's hope that next year, peace, scientific knowledge, diversity, and humanity will be core values of our society. We can only lead by example!
about 1 year ago
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I have received 5 invitations to review papers during the past 48 hours. I understand authors want to finish their manuscripts before they go on holidays, but reviewers also need a break
about 1 year ago
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Marta Shahbazi
about 1 year ago
🎉 Excited to announce job openings in our new lab
@mpi-bio-fml.bsky.social
in Tübingen!🇩🇪Looking for enthusiastic colleagues to explore regeneration together! We have positions for: 🔬 Research Technician 💻 Bioinformatician 🎓 PhD Studentship 🧪🔬📖 Postdocs Details and links below👇
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Marta Shahbazi
Leah Hazard
about 1 year ago
@theguardian.com
please fix this inaccurate headline ASAP: 25pc of all births were *planned* sections. The total proportion of sections (including planned and unplanned) is closer to 40pc. The header and the article are both misleading.
www.theguardian.com/society/2024...
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One in four babies in England delivered by caesarean section, NHS data shows
Increase due to a growing number of complex births caused by rising obesity rates and women having children later in life
https://www.theguardian.com/society/2024/dec/16/one-in-four-babies-in-england-delivered-by-caesarean-section-nhs-data-shows?CMP=Share_iOSApp_Other
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Marta Shahbazi
Nature Portfolio
about 1 year ago
A potential new mRNA-based therapy for pre-eclampsia is demonstrated in a mouse study published in Nature. The method involves targeted delivery of mRNA to the placenta to restore normal maternal blood pressure and improve foetal health. 🧪
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Placenta-tropic VEGF mRNA lipid nanoparticles ameliorate murine pre-eclampsia - Nature
A platform for mRNA lipid nanoparticle delivery to the placenta to treat pre-eclampsia is shown to improve fetal and maternal health in mice and has potential clinical applications in obstetric disorders and women's health.
https://go.nature.com/41vacXz
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On my way to the EMBL PhD symposium. Really excited about the topic Biology outside the box! However, I will miss my daughter’s Christmas play. That’s the reality of a mother scientist. Sometimes you sacrifice family, sometimes you sacrifice science, and hopefully you get the balance right
about 1 year ago
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Marta Shahbazi
Sergiu P. Pasca
about 1 year ago
@bsky.app
we really need a bookmark function 🙏
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I am so happy to be part of this amazing programme. Thanks to the EMBO postdoctoral fellowship I made friends and found collaborators. Now it is the time to make the most of the EMBO YIP!
www.embo.org/press-releas...
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Twenty-seven scientists become EMBO Young Investigators – Press releases – EMBO
The group leaders join an international network of nearly 800 life scientists and receive financial support
https://www.embo.org/press-releases/twenty-seven-scientists-become-embo-young-investigators/
about 1 year ago
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reposted by
Marta Shahbazi
MRC Laboratory of Molecular Biology
about 1 year ago
Congratulations to
@marta-shahbazi.bsky.social
, Group Leader in
@cellbiol-mrclmb.bsky.social
, who has joined the EMBO Young Investigator Programme! Read more here about the programme and Marta’s research here:
www2.mrc-lmb.cam.ac.uk/marta-shahba...
#LMBNews
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Marta Shahbazi
Johanna Joyce
about 1 year ago
Women are under-represented at senior levels in
#academia
globally, & across all
#science
🧪 disciplines, as shown by these "scissor-shaped curves" ✂️ So how can we ever achieve
#gender
#equality
? We discuss various strategies in this
#Cell
Commentary
#WomeninSTEM
www.cell.com/cell/fulltex...
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