Ana Tufegdzic Vidakovic
@anatv.bsky.social
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Group Leader at MRC Laboratory of Molecular Biology. Transcription, RNA Polymerase II, Ubiquitin
@mrclmb.bsky.social
MRC LMB is looking for a new group leader in Chemical/Synthetic Biology. Come and join us in this fantastic institute! Core funding, amazing science all around you and great collaborative colleagues are just some of the highlights. Please share the news!
add a skeleton here at some point
about 2 months ago
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Looking forward to presenting at the Cambridge RNA club again! If you are interested in gene regulation and around Cambridge, stop by!
add a skeleton here at some point
3 months ago
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reposted by
Ana Tufegdzic Vidakovic
Susan Shao
6 months ago
~1 week left to register for the EMBO workshop on RNA meets protein decay!
#EMBOrnaDecay
Come join us for a fun time and invigorating scientific discussions in Vienna!
meetings.embo.org/event/25-rna...
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RNA meets protein decay
Establishing the composition of RNAs and proteins that defines the identities and functions of cells relies not only on the regulated biosynthesis of these molecules, but also equally importantly, on…
https://meetings.embo.org/event/25-rna-decay
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The first PhD student of our lab, 5'-Ivan Shlamovitz, has passed his viva with flying colours! What a special moment! The whole lab (and many friends at the LMB) are proud! 👏😁
7 months ago
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The first paper from our lab is online! A wonderful collaboration with
@scottbscience.bsky.social
lab. We discover that Pol II is extensively regulated by Ubiquitin at the beginning of the transcription cycle!
www.cell.com/molecular-ce...
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CRL3ARMC5 ubiquitin ligase and Integrator phosphatase form parallel mechanisms to control early stages of RNA Pol II transcription
Cacioppo, Gillis, Shlamovitz, Zeller, et al. show that CRL3ARMC5 ubiquitylates RNA Pol II at early stages of transcription as part of a major homeostatic RNA Pol II turnover mechanism. CRL3ARMC5 and the Integrator phosphatase act as complementary pathways, monitoring the quantity and quality of RNA Pol II complexes before they are licensed into elongation.
https://www.cell.com/molecular-cell/fulltext/S1097-2765(24)00949-3
10 months ago
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