In OFID, Yuki Nakano and colleagues investigate the signals and characterize the clinical features of optic nerve disorders related to oxazolidinones using the FAERS database. https://academic.oup.com/ofid/advance-article/doi/10.1093/ofid/ofaf520/8242009

MAHA gold-standard science. By @glaucomflecken.bsky.social

feels significant that mass-market LLMs like ChatGPT are now capable of generating extensive natural-language dossiers about a given user's interests, location, preferences, identifying information, and more simonwillison.net/2025/May/21/...

This paper has had such a journey that I feel compelled to share it. It started when our ID PharmD resident gave an in-service to @templeid.bsky.social as a 'how-to' use oral beta-lactams for systemic Gram-negative infections, then was submitted, turned down, 1/ academic.oup.com/ofid/article...

Normally a paper that concludes “Should you do X? It depends.” wouldn’t be at the top of my reading list but I think our (@jgpharmd.bsky.social, @emilylheil.bsky.social) new case-based paper on PO beta-lactams for GNRs highlights nuances & challenges generalizations academic.oup.com/ofid/article...

I wrote about the era of Mass Intelligence. GPT-5 and Nano Banana are examples of how advanced AI is now making their way to many users, at scale, as both performance & efficiency keep improving. We are going to see a lot of weird things happening, all at once www.oneusefulthing.org/p/mass-intel...

Today, FDA approved seasonal covid vaccines for people 65+ and people with health conditions. I have updated my FAQ with more questions and answers from readers. www.forceofinfection.com/faq-on-fall-...

CDC list of medical conditions associated w higher risk for severe COVID-19, you need 1 to to qualify for vaccines now: -Cancer (solid or blood cancers) -Cerebrovascular disease (e.g., stroke) -Chronic kidney disease (any stage) -Chronic liver disease (fatty liver, cirrhosis, autoimmune hepatitis)

Finally a healthy reason for a second helping at Thanksgiving! Grab those Friday vaccine appointments while they last!

𝗡𝗲𝘄 𝗠𝗲𝗱𝗶𝗰𝗮𝗹 𝗘𝗱𝘂𝗰𝗮𝘁𝗶𝗼𝗻 𝗔𝗿𝘁𝗶𝗰𝗹𝗲! Many learners are more facile with the use of large language models in medicine than their supervisors are. The authors provide an approach to clinical supervision that can mitigate the perils and amplify the promise of AI. nej.md/47okmwr

@jgpharmd.bsky.social we are definitely missing a good crossover opportunity for cover art for the next edition. I’ve attached a mockup here. I can’t help it who the readers will assume is whom.

OpenAI's study mode isn't perfect, but it is a step forward for a few reasons: 1) Shows labs taking educational use & misuse more seriously (Google also has LearnLM) 2) Addresses a key issue with trying to use AI in education - that AI gives answers rather than tutoring and helping 3) Easy to access

🔬 New study: Olorofim shows promise for patients with invasive fungal disease who have limited treatment options. The first antifungal in its class, it demonstrated good tolerability and encouraging outcomes. Read more 👉 pubmed.ncbi.nlm.nih.gov/40541222/ #IFD #Olorofim #Antifungal

It’s out! IDSA #cUTI guidelines 7/17/25. Now the fun begins….😌 #IDsky #AMSsky @idsainfo.bsky.social @sidpharm.bsky.social www.idsociety.org/practice-gui...

The Challenges of Nocardia Susceptibility Testing and Inter-Species Susceptibility Patterns ✅ Just Accepted #IDSky

It was a pleasure to work on this project with our ID pharmacist colleagues. AI has a lot of potential in this space, especially with the basic interpretation of data, but still needs human guidance to work through the complexities of patient management. Looking forward to doing more of this!

I wrote about "brain damage" from AI. Despite scary headlines, AI won't hurt you brain, but it can undermine your thinking and learning. Increasingly, however we are finding ways it can help us think and learn instead (some included prompt examples as well). www.oneusefulthing.org/p/against-br...

🚨BREAKING: IDSA, along with AAP, APHA, ACP and others, has filed a lawsuit against HHS/Secretary Kennedy to stop unlawful changes to vaccine policy and defend public health. We refuse to stand by while America’s public health safeguards are torn apart. bit.ly/4lm7UkW

I've often wondered about this question--does a shorter duration of antibiotics spare the microbiome, or are any antibiotics bad for the microbiome www.idsociety.org/science-spea...

These recommended pediatric and adult vaccine schedules reflect ACIP guidance, and were archived on Feb 18, 2025. 🚨 If you- or your kids are behind for any reason, get caught up now. Parents: cancer-preventing HPV vax is approved for all kids 9 yrs and up. Please don’t miss out on this protection.

The next #Communicable episode drops Monday, 19 May! CMI Comms editors @marcbonten.bsky.social @gurujosh.bsky.social @erinmccreary.bsky.social & @dremilymcd.bsky.social discuss key latebreaker trials presented at #ESCMIDGlobal & whether they should change your practice 🔍 #IDSky #MedSky #clinmicro

🆕🔥Systematic review and consensus guidelines for dose adjustments with many 🌟 Prof. Jason Roberts & Prof Manjunath P Pai The pharmacokinetics of antibiotics in patients with obesity. #IDsky #EMIMCC www.thelancet.com/journals/lan...

such a joy to discuss PSSA/MSSA domains of SNAP. incredible work led by @gurujosh.bsky.social @steventong.bsky.social conversation w/ the fabulous @angelahuttner.bsky.social joint effort @escmid.bsky.social Communicable & @sidpharm.bsky.social Breakpoints podcast podcasts.apple.com/us/podcast/s...

🧵1/N New study published in @jama.com on re-emergence of vaccine-eliminated infectious diseases under declining vaccination in the US. We model long-term risk and conditions for return to endemicity for measles, rubella, polio, & diphtheria. Collab w/ @Mathewkiang.com jamanetwork.com/journals/jam...

This new peer-reviewed collection from @aamctoday.bsky.social includes freely accessible tools to help effectively integrate AI into educational environments. www.aamc.org/about-us/mis...

@steventong.bsky.social @gurujosh.bsky.social presenting results of the MSSA domain of the SNAP 🫰 trial at #ESCMID2025. just amazing work by amazing humans - congratulations on this practice changing effort!! #idsky #medsky #amssky

@steventong.bsky.social presents the results of the PSSA domain of the SNAP 🫰 trial - the worlds largest trial of staph aureus bacteremia - at #ESCMID2025 fluclox resulted in higher mortality and more AKI compared to penicillin for PSSA

🔥Breaking news🔥 US FDA approved Blujepa (gepotidacin) for treatment of uncomplicated urinary tract infections (uUTIs) in female adults and paediatric patients 12 years of age and older #IDsky #utisky #medsky #AMSsky www.gsk.com/en-gb/media/...

The data so far on AI-as-a-tutor shows just letting students use AI chatbots can undermine education because the AI gives the illusion of learning But AIs properly prompted to act like tutors, especially with instructor support, seem to be able to boost learning a lot through customized instruction

‼️The @idsainfo.bsky.social cUTI guideline 📄 draft is now available for public comment🗣️! This version has been reviewed by 15+ orgs & revised according to extensive feedback provided to us. www.idsociety.org/practice-gui... UTIsky IDsky Medsky PharmSky

If you feel like everyone is sick right now, you are right. Flu is doing something unusual - outpatient visits just hit 7.0%, surpassing January's peak. substack.com/home/post/p-...

Wow well ok www.congress.gov/bill/119th-c...

Maybe this mill motivat AI to figure out how to get rid of the pharmacy benefit managers?

Looking for the latest guidance on intra-abdominal infxns? SIDP has you covered! 😍 Check out this infographic on new #SIS IAI Guidelines developed by Dr. Clara Ni! 💊 This medical education provided by an educational grant from Innoviva Specialty Therapeutics. Download: https://buff.ly/4jrr8Vy

Finally! Some helpful material to educate the public on the penicillin allergy myth, from one of my fav podcasts 🎙️, #Freakonomics 👇🏻 #IDsky #Pharmsky #AMSsky 🔗: podcasts.apple.com/us/podcast/f...

After watching researchers try to recover bodies from the 1918 flu in the Arctic, I went back to school to study the social history of epidemics. I couldn't understand why 1918 sparked no major memorials, no novels, no plays. How could societies collectively agree to forget mass death? Welp.

How well does academic performance (GPA, class rank, instructor evaluations) predict job performance? Contrary to some recent headlines, it’s actually pretty good! Here are a few highlights from a recent meta-analysis 🧵, available here: doi.org/10.1037/apl0...

It's that time of year again. Here are my top 10 ID papers of 2024 1. My opinion 2. Practice changing, paradigm-shifting or dogma challenging 3. Not COVID 4. Alphabetical order by first author 5. CoI for 4 and 5 (I am an author) Summary slide here, details in thread #IDSky #Top10IDpapers

And in a summary of today’s bird flu news, we have Dr. Ellis Cheever from the critically acclaimed movie “Contagion” from the before time of 2011.

🔥🆕️CACTUS Multi center real world data on ceftaz/avi vs ceftol/tazo for MDR PsA bacteremia or pneumonia Overall similar clinical success including mortality, recurrent infection & resistance #idsky #EMIMCC #medsky www.thelancet.com/journals/lan...

I think a fun teaching exercise for medical students would be to each take a common clinical pearl and trace the citations until you find the primary data it's based on.

I'm crabby today but I wish we could have a little less pearl-clutching over "the children are citing AI hallucinations" and a little more over "tenured academics are citing documents that cite documents that cite documents that cite documents that don't support their claims."

it’s the happiest Thursday because @sidpharm.bsky.social and the @escmid.bsky.social PK PD study group are bringing back ICAAC (in spirit)!!!! Registration will open next week! The Midwest in the summer is magical - come join us! sidp.org/page-1543694 #idsky #amssky #pharmsky

I think firms worrying about AI hallucination should consider some questions: 1) How vital is 100% accuracy on a task? 2) How accurate is AI? 3) How accurate is the human who would do it? 4) How do you know 2 & 3? 5) How do you deal with the fact that humans are not 100%? Not all tasks are the same.

A real, actual thing BCBS is doing youtube.com/shorts/vWA2a...

🆕 #Breakpoints Episode: Drs. @annegretemartson.bsky.social, Megan Wimmer, and Evan Clemens join me to discuss all things (Val)ganciclovir!!! #idsky #pharmsky #amssky @sidpharm.bsky.social 🎧 sidp.pinecast.co

Academic decision algorithm v 7.0- a testament to #SocialMedia peer review, as all versions past 1.0 were improved upon by feedback from colleagues on social media

Ocular infections are some of the most challenging to treat. Uncertain penetration of systemic antibiotics into ocular tissue, need for intravitreal antibiotics, high risk for vision loss and even enucleation. This review in CID is fantastic. #IDSKY 🧪 academic.oup.com/cid/article/...

🧵of beta-lactam antibiotic learning points I developed for learners on rotation. Feedback welcome - there are a ton of brilliant people here who do really cool science in these areas. Would love to learn more! Hope you enjoy this learner-🎯tweetorial #IDSky #PharmSky #PharmEd #MedEd 1/n

People make prompting too hard. Most people would benefit from just using good enough prompting techniques. I outline some basic rules, including why “treat AI like an intern” is no longer the advice I would give new AI users. www.oneusefulthing.org/p/getting-st...