Mechanisms of protein degradation in atrophying muscles: what have we learned during the past decade? www.jbc.org/article/S002...

Mitochondrial dynamics proteins have other functions than just regulating mito dynamics, but they are often forgotten. Congrats to the team and especially Rémi Chaney and @gillesgouspillou.bsky.social who did the heavy lifting on this review 💪 physoc.onlinelibrary.wiley.com/doi/10.1113/...

Strength training improves mitochondrial bioenergetics and skeletal muscle integrity in women with Myotonic Dystrophy Type 1. Thanks to everyone involved, notably @gillesgouspillou.bsky.social, @jpleduc-gaudet.bsky.social, E. Duchesne, L. Girard-Coté. onlinelibrary.wiley.com/doi/10.1111/...

Hopefully of interest to scientists and exercise practitioners with and interest in muscle mass and functional gains in human volunteers. doi.org/10.1113/JP28... @jphysiol.bsky.social

Excited to share our latest paper, out in @cp-cellrepmed.bsky.social, investigating the impact of physical activity on physical function, mitochondrial energetics, ROS production, and Ca2+ handling across the adult lifespan in men. Spearheaded by M Cefis & V Marcangeli www.cell.com/cell-reports...

Experimental Evidence Against Taurine Deficiency as a Driver of Aging in Humans onlinelibrary.wiley.com/doi/full/10....

Our new very collaborative paper showing that muscle myosin has a reduced energy demand in diabetes. Big impact on weight control in our mind!!! Thank you to everyone involved and funders @lundbeckfonden.bsky.social @novo-nordisk.bsky.social @ucph.bsky.social @myoblue.bsky.social #diabetes

📣 CALL FOR PAPERS 📣 Organised by @pgreenhaff.bsky.social & focusing on: 🚑 Injury and rehabilitation ⛰️ Altitude physiology 🦵 Muscle adaptation 🚴 Exercise training 💉 Pharmacological interventions ⚙️ Body composition 🔗 buff.ly/2sVbnLk

The PowerLab ( uofgpowerlab.weebly.com ) is having some big turnover this summer and this opens the door to take on new PhD students to work on projects related to muscular adaptations to use/disuse across various structural levels. Happy to chat!!

www.nature.com/articles/s41... A human brain map of mitochondrial respiratory capacity and diversity

Attention mitochondriacs! Mitochondrial supercomplexes by cryo-electron tomography. How can you not be blown away by how beautiful this is? Fascinating that ATP synthase is largely organized as dimers since this is one of the putative configurations of mPT pore. www.science.org/doi/10.1126/...

« Use of sedentary subjects as the control group has led to potentially misleading interpretations. If physically active individuals were designated as the control group, a different interpretation would have been drawn ». 21-year-old gem. pubmed.ncbi.nlm.nih.gov/15317985/

Macrophages excite muscle spindles with glutamate to bolster locomotion www.nature.com/articles/s41...

New article alert from our group! If you have ever wondered what circulating factors associate with extremes of physical function in advanced age in humans, this provides some insights and raises plenty of questions: pubmed.ncbi.nlm.nih.gov/40059508/

Immunomodulatory role of the stem cell circadian clock in muscle repair www.science.org/doi/10.1126/...

Clonal dynamics and somatic evolution of haematopoiesis in mouse www.nature.com/articles/s41...

Single-nuclei sequencing of skeletal muscle reveals subsynaptic-specific transcripts involved in neuromuscular junction maintenance www.nature.com/articles/s41...

Structure of mitochondrial pyruvate carrier and its inhibition mechanism www.nature.com/articles/s41...

Proximity proteomics reveals a mechanism of fatty acid transfer at lipid droplet-mitochondria- endoplasmic reticulum contact sites www.nature.com/articles/s41...

@DrJimmyBagley and I wrote this while he was fighting (and beating!) cancer. Grateful for him as my colleague and friend. “A primer on global molecular responses to exercise in skeletal muscle: Omics in focus”. Cutting edge! @JSHS_MedHealth #myoblue www.sciencedirect.com/science/arti...

🚨APPLICATIONS CLOSE FRIDAY 21st FEBRUARY🚨 For our 2025 Editorial Board Fellowship scheme! Read about Josiane Broussard's experience as an Editorial Fellow🎓👇 🔗 https://buff.ly/2s5K83y

💪CALL FOR PAPERS💪 For our "New perspectives on the physiological basis of muscle loss" #SpecialIssue! This issue will highlight the latest research underpinning the integrative mechanisms driving muscle loss! Click the link and submit your research! 🔗https://buff.ly/3D97oFr

When studying mitochondria, it is essential to consider the impact of physical activity. Some findings attributed to 'aging' might actually be the result of decades of physical inactivity. ⬇️ www.cell.com/cell-reports...

Excited to share our latest paper, out in @cp-cellrepmed.bsky.social, investigating the impact of physical activity on physical function, mitochondrial energetics, ROS production, and Ca2+ handling across the adult lifespan in men. Spearheaded by M Cefis & V Marcangeli www.cell.com/cell-reports...

The roles of mitochondria in global and local intracellular calcium signalling www.nature.com/articles/s41...