10+ years of vision 👁️research in mice 🐭recasts our ideas about the brain 🧠and sharing data 🧪📈... a brief guide 👇 Thanks to many colleagues and @gtresearch.bsky.social @gt-neuro.bsky.social for connecting us w @us.theconversation.com

This paper is the result of >20 yrs of hard work by talented students, postdocs and collaborators, but none more than my co-author Ren Ng and his team in EECS. 1/n Novel color via stimulation of individual photoreceptors at population scale | Science Advances www.science.org/doi/10.1126/...

🧪 The Sjöström Lab in Montreal is looking for a postdoc! We study cortical circuits, synaptic plasticity, and NMDAR signalling using custom 2-photon microscopy and optogenetics. We seek candidates with strong patch-clamp and/or 2-photon imaging expertise, and a relevant publication track record.

2. Systems Neuroscience PhD position, supervised jointly with Sarah Ruediger @ruedigersarah.bsky.social This is to investigate the differential circuits involved in habitual and goal-directed behaviours. www.findaphd.com/phds/project...

Anyone looking for a PhD in NeuroAI (models of the visual system to spatial system)? @amansaleem.bsky.social and I are looking for someone to start in October. More details here: www.findaphd.com/phds/project... Get in touch with either of us if you’ve got questions!

FDA plans to phase out animal testing requirement for drug testing and replace it with “AI-based computational models of toxicity” and organoid toxicity testing www.fda.gov/news-events/...

Check out our latest paper today in Nature: “Goal specific hippocampal inhibition gates learning” www.nature.com/articles/s41... By Nuri Jeong, Xiao Zheng, Abby Paulson, Steph Prince and colleagues.

How does the brain work? Scientists are closer to the answer with the largest wiring diagram and functional map of a mammalian brain to date. 🧵 🧠📈

Brain gain? Toronto's @UHN hospital system will announce a strategy to attract U.S. health scientists - plan to be unveiled Monday. Website isn't up yet, but U.S scientists interested check here Monday. Hopefully other hospitals & universities follow UHNCanadaleads.ca

This was a difficult thread to write.. Our research on antidepressants has been supported by NIMH for 10 years. Until the last moment, their comms team was still trying to put out a press piece about this work for us. I’m so sorry.

OK here it is, the moment you have all been waiting for! Our advert for 5 posts here at Glasgow: Cognitive neuroscience/psychology. Closing date May 12 - please spread the word www.nature.com/naturecareer...

Interesting work by Tony Lien & @haiderlab.bsky.social. They reveal how some frontal cortex neurons mirrors V1 neurons. Responses lag visual cortex (VC) by ~25ms, with strikingly similar receptive fields—yet lacking a topographic map. Crucially, silencing VC abolishes these responses. Congrats

Exciting new results from the lab -- *visual* receptive fields in motor and cingulate cortex! Great work from Tony Lien 🧠🧪

Congrats to Kayla Peelman on publishing her paper AND defending her thesis in the same week ✨🎉 Click 👇 to see how the environment shapes the timing and selectivity of vision 👁️🧠🧪 www.cell.com/current-biol...

Compelling pushback from @jmgrohneuro.bsky.social and the Board of Scientific Counselors at the National Institute on Mental Health (NIMH) regarding termination of tenure-track investigators driven by DOGE. 1/2

Lateral inhibition from parvalbumin neurons in mouse primary visual cortex reduces sensitivity to contrast; lateral inhibition from somatostatin neurons changes the gain of contrast sensitivity 🧪🧠 @haiderlab.bsky.social @gtresearchnews.bsky.social s.bsky.social www.nature.com/articles/s41...

Congratulations to these two outstanding physician-neuroscientists! Many people now are familiar with the fascinating fundamental research of @michellemonje.bsky.social but most people probably don't know she is a truly great physician. I'm fortunate to be inspired by her every day, in every way.

Super interesting... phenotyping social behavior + touch in 7 monogenic rat models of autism

just noticed @jdelrosario.bsky.social has joined us here - welcome and congrats on a great study 👇

(1/10) Happy to share a science update! 🧠🧪 Our @natureneuro.bsky.social article shows how inhibitory neurons calculate “subtraction” or “division” to adjust visual sensitivity! This one has it all – behavior, optogenetics, modeling, cell types, subthreshold mechanisms. Quick thread 🧵below

I am very proud to announce that my PhD paper finally came out in Cell! In this *very* collaborative study, we develop and release a deep-learning approach to predict neuron type identity from their electrical signature. doi.org/10.1016/j.ce... 1/16 🧵

Our paper @dulaclab.bsky.social on social homeostasis is online today! We characterized “social rebound” behavior after social isolation in multiple mouse strains and revealed its neural basis. Intriguingly, soft touch plays a key role in satisfying social need! www.nature.com/articles/s41...

Confirmed (by many sources) news about 50 NIH Study Sections being allowed to announce meetings in the Federal Register. As usual, MANY more questions than answers... 1/2

Amazing opportunity for a UCL faculty position:

Lab manager position open in my lab at EMBL Rome--particularly looking for people with experience in 2-photon microscopy in mice in vivo. DMs open if you have questions--reposts welcome! embl.wd103.myworkdayjobs.com/en-US/EMBL/j...

The Judge said NIH grants for medical research had to be unfrozen; the White House found a way to refreeze it. talkingpointsmemo.com/edblog/white...

New paper alert! Have you ever looked at single-trial fMRI activation maps? If so, you know that they are super variable. Here we show that the variability is not just noise. In fact, the same task can consistently elicit different activation patterns. www.nature.com/articles/s41...

Great explainer on the Federal Register block and how it affects all NIH grant-related activities 👇

If the block on the Federal Register isn’t removed in the next few months, I fear a majority of labs will close within a year. This small procedural wrench has the power to kill US science indefinitely, losing an entire generation of discovery and innovation.

Join us! Science Homecoming helps scientists reconnect with communities by writing about the importance of science funding in their hometown newspapers. We’ve mapped every small newspaper in the U.S. and provide resources to get you started. Help science get back home 🧪🔬🧬 🏠 sciencehomecoming.com

ATTENTION (PLEASE SHARE) If anyone has or knows of any positions that might be appropriate for the NIH staff members who were terminated, please post the information in this thread. There are lots of talented and accomplished people who may be looking for new opportunities.

In case folks are interested in contacting their congresspeople about the NIH indirect cuts with some estimates of what they would mean for institutions in their state, here are some estimates based on published F&A rates and funding ... let me know if you want a particular state

'The appropriations committees in both houses rejected Mr. Trump’s proposal to slash payments to universities for overhead — the “indirect costs” of research financed by the health institutes.' Had forgotten about this. Let's see how much has really changed in the past 8 years. (Yes, hopes not up)

ATTENTION If you are someone who had an F31-Diversity (or similar) application submitted this cycle, please DM me here, contact me on signal (jeremymberg.78), or email me at [email protected]. I will keep all information confidential. 2/n

Neuropixels and Optogenetics are delighted to announce the birth of Neuropixels Opto Combining high-resolution electrophysiology and optogenetics Today in bioRxiv 960 sites, 28 emitters, 2 colors By Lakunina, @karolinazsocha.bsky.social, Ladd, et al www.biorxiv.org/content/10.1... (1/2)

So excited to see this out, heroic effort by the brilliant Sara Mederos, uncovering the detailed brain mechanisms of how animals learn to overcome their instinctive fear responses, from neural circuits & cell types down to synaptic plasticity mechanism! www.science.org/doi/10.1126/...

Goes without saying for scientists: This means Musk and his kids have access to grant applications, study section reports, internal scoring, RPPRs. The core of the best ideas in US science. Will they steal those ideas? #scicomm #neuroskyence #evodevo #publichealth 🧪🧑‍🔬

Let’s try something. We here at @altnih4science.bsky.social want to boost descriptions of NIH-funded science. If you’re a scientist with a post or thread that describes your work, please tag us or DM us, and we’ll repost. We’ll use the #NIHFundsGreatScience hashtag so people can read in future. 🧪

This account is for sharing info with US scientists, both extramural and intramural to NIH, about attacks on science in the US. Education is power, and we can help advocate for science and medicine together. 💪🧪 We are a team of NIH people. Please ask us questions you might have.

If you have an NIH award pending, I'd encourage you to check the ERA commons portal. For our pending award, *all* of the relevant information is now missing (the reviews are not accessible, the dates have all been changed, all of the history of the process isn't accessible)!

New preprint: "The geometry of the neural state space of decisions", work by Mauro Monsalve-Mercado, buff.ly/42wVHD5. Surprising results & predictions! (Thread) We analyze neuropixel population recordings in macaque area LIP during a reaction time, random-dot motion 1/

Academic Skyers: I am compiling a list of policies and statements from various universities about how they are handling the "pause" in terms of stopping expenditures (or not). Please respond to this post with your institution and materials. THANK YOU!

This is legit - the organizers (including unions) are organizing. When I ask those in the know what we can do that will actually matter, the answer includes collective action of this type. I'm joining @nancykanwisher.bsky.social and all the others for this Thurs 3p ET effort. I hope you do too!

I wrote about the concept of agency (both human and artificial) in the year 2025. gracewlindsay.com/2025/01/24/2...

Please repost! We’re trying hard to sort out rumors from truth + would like to hear from anyone affected by the new federal orders + NIH pause. Patients, scientists, health equity researchers: please contact us below. We won’t share anything without your permission. www.statnews.com/2025/01/25/t...

Want to see the numbers for how NIH funding impacts your state? Remind your Representatives, Senators, and fellow citizens how federally-funded biomedical research advances health, created jobs, and fosters innovation and economic growth. www.unitedformedicalresearch.org/nih-in-your-...

The NIH Is literally prohibited by law from commenting on the new NIH restrictions. The NIH can't fight this fight for you. Scientists who want to help people, this has to be your fight.

This was a period of time where taxpayer funded initiatives funded science at unprecedented rates. These efforts made America a global social, economic, and educational powerhouse. In 1966 at the peak of the Apollo program, we spent 2.5%GDP on science. Now? Now we spend 0.6%GDP on science. 🧪