Unreal, the impact this is having on scientists. I spent over 700 hrs writing 4 grants submitted Apr-Sept that *might* have been funded next Apr; 2 abt to be 3 apps missed review bc of shutdown. In normal times takes 9-24 mo to get a grant funded. No hope for labs like mine. Literally no hope.

While the government was shut down, 379 NIH study section meetings (containing 24,380 grant applications) were postponed. NIH is committed to getting these reviewed, but please be patient and understanding with staff, as this is a complex and heavy lift.

Our new paper is out! Amyloid plaques switch on microglial GPC4, increasing neuronal tau uptake & toxicity—defining an amyloid→glia→tau pathway & a potential drug target. Pleasure to work with our collaborator @jcoutinhobudd.bsky.social. doi.org/10.1186/s130... #Alzheimers #Glia #Tau #Amyloid

🚨 We’re hiring! 🧪 @uvabio.bsky.social UVA Biology is recruiting multiple tenure-track Assistant Professors in neuroscience as part of a $75M Brain & Neuroscience Initiative. 🧠 Apply by Oct 15, 2025. Start Aug 2026. 👉 apply.interfolio.com/172892 #Neuroscience #FacultyJobs #NeuroJobs #Biology #UVA

β-Amyloid induces #microglial expression of GPC4 and #APOE leading to increased neuronal tau pathology and toxicity Brandon B. Holmes, Thaddeus K. Weigel, Jesseca M. Chung...James A. Wells #AlzheimersDisease #drosophila #amyloid #microglia @ucsanfrancisco.bsky.social bit.ly/3HXP98J

It was fantastic to work with Dr. Holmes and colleagues to integrate work from flies to humans in Alzheimer’s molecularneurodegeneration.biomedcentral.com/articles/10....

The community of Drosophila researchers is amazing, mutually supportive and collaborative. Right now a key resource for our community, @flybase.bsky.social , is threatened by the cancellation of its NIH grant and is seeking community help in raising short term funds 1/n 🧪 please share

Fly folk: The Amazing and essential @flybase.bsky.social is in existential need due to Trump termination of the grant that supports this vital resource. Please donate to help keep Flybase alive. I just did. Info here on how to make a tax deductible donation: wiki.flybase.org/wiki/FlyBase...

So excited this is finally out! 🎉 doi.org/10.1002/glia...

i wrote an essay for @thetransmitter.bsky.social about what it feels like to serve on an NIH grant review panel (study section) right now www.thetransmitter.org/craft-and-ca...

If your representatives are not REPRESENTING YOU and making life harder for you, you need to fire them. That's it.

WOW, WE'RE DOING TARDIGRADE NEUROSCIENCE? Noice! www.nature.com/articles/d41...

The man behind me in the grocery line just told the cashier to continue ringing through to his stuff and he was gonna pay for mine. It was literally $200. He said that he’s been going through some stuff lately and he just wants to do something good. 🥹 Reminder: there is still good in this world. ❤️🙏

“Campus leaders need to understand that their capitulations and concessions only further empower the greatest threat to higher education since the Red Scare, if not earlier.” (The AAUP contends that this moment is far worse.) Act Now. Never Cave. #DefendHigherEd

Karolinska is looking for 20 (!!) assistant professors and offering 6 year appointments with ~1M USD startup packages. ki.se/en/about-ki/...

Wow. Just wow. University of Virginia President Resigns Under Pressure From Trump Administration www.nytimes.com/2025/06/27/u...

URGENT: FlyBase has lost practically all its funding overnight; even user fees are tied up in denied grant funding. 🤬🤯 Any lab using @flybase.bsky.social please donate using the link in post below. This incredible community, on whose backs our #Drosophila labs depend, can't be left out to dry.

Happy to present a single cell atlas of ALL glia, in BOTH sexes of an animal (in vivo validated!)! Fab work by postdoc @glia-maria.bsky.social, team, & collaboration with @manusetty.bsky.social . Find insights into glia, new analytics and ML models, and browse our companion website (wormglia.org)

Calling all Neuroscience postdocs! 🧠 Share your research through SPiNES (Seminars from Postdocs in Neuroscience: Extramural Series) from the NYUGSoM Department of Neuroscience. Applications close 08/20/25. Apply today! 👉 nyumc.qualtrics.com/jfe/form/SV_... #Neuroscience #Postdoc #ResearchOpportunity

"We are speaking on behalf of hundreds of NIH staff who are standing up together to say: WE DISSENT. I am so scared about doing this but I am trying to be brave for my kids because it's only gonna get harder to speak up." Thank you to Dr. Jenna Norton and NIH scientists for your courage!

ACTION ITEM-----ACTION ITEM Implementation of Schedule F This is what a lot of us have been worried about. This allows for many civil service positions to replaced with political appointees. This could include NIH institute directors and even POs. BUT THERE IS A COMMENT PERIOD... 1/n

Know anyone looking for a lab specialist/technician job? The Ross lab is hiring! This position will help the lab with our research on anti-tumor immunity in high-grade glioma. Incredible training environment!! 🐭🔬🧪🦠🧠 jobs.virginia.edu/us/en/job/R0...

After 21 years at my dream job, I’m very sad to announce my early retirement from the National Institutes of Health. My life’s work has been to scientifically study how our food environment affects what we eat, and how what we eat affects our physiology.

Nature has a story on science tattoos, in which they quoted me about my 2011 book, Science Ink (still in print!) www.nature.com/articles/d41...

I wonder, for those of us on a tenure clock, how will this situation factor in? We’re not playing the same game we set out to play.

Bad news for all of us: champion for inclusion & excellence @ NIH/NINDS Dr. Michelle Jones-London is leaving NINDS.💔 She helped launch the career of countless cutting-edge neuroscientists & set the standard for training. Great news of course for where ever she goes next. 🧪🧠@jeremymberg.bsky.social

NIH PostBac program is open again! And I will be hiring! #JobPostComing www.training.nih.gov/research-tra...

We're disappointed to see Ben Barres's powerful book "The Autobiography of a Transgender Scientist" among the ~400 titles removed from the Naval Academy Library. Needless to say, we're proud to have published his book and will keep it — and his memory — alive.

The horror show continues at NIH I am hearing (reliably) that RIFs have started with entire institute Communication branches being terminated since their jobs not longer exist (reduction in force). But that is not all...

STILL no New or Competing Renewal awards from NIGMS. Only NIGMS seems to not be making these awards.

In the midst of everything that’s going on, it’s so nice to be able to appreciate the little things. My lab spent some time away from it all to enjoy time together (and the rest of the amazing scientific community) at the UVA BIG center retreat ❤️

UVA BIG Center retreat with @tajieharris.bsky.social, @lukensjohnr.bsky.social, Alban Gaultier, and our invited speaker @dimitry-krementsov.bsky.social. Happy to have him out here in beautiful VA!

The most common mistake I see with writers is assuming readers know way more than they readers do. Though, it looks a little different for ECRs vs Sr scholars. ECRs assume everyone knows all the background info. Sr scholars assume too much technical knowledge (As is obvious...) 2/2

Have you seen this incredible TEDx MIT talk by Linda Griffith? 2 years ago and still wow! How lucky am I that I get to work with her? www.youtube.com/watch?v=_A_T...

This thread shares that UMich, Yale, U of AZ have set aside funds to support researchers who are getting these disgusting grant announcements from NIH… Who else? This small step should spread…

U of Michigan @umich.edu set aside funds from central to support researchers with unexpected disruption in federal funding for up to 6 months. Are any other institutions doing this? Seems like a good move. #Medsky #NIH #federalfunding #researchfunding 🧪 record.umich.edu/articles/uni...

The U of Arizona was building a new medical research facility in Phoenix, but it’s now on hold because of uncertain federal funding. It was proposed as a research hub to “find new ways to diagnose, prevent and treat cancers, infectious disease and autoimmune disorders”. Great job DOGE!

The general vibe we are getting across #NIH institutes is deeply bleak — that the agency is nearly, if not already dead. Top people are leaving or have left. Nearly everyone's looking for other jobs. People still care about what NIH was, but are growing resigned to its death. 1/

Substantial updates to the list of cancelled grants👇 - THANK YOU to all who have contributed. Crowdsourcing restores faith in humanity. - It's still a work in progress. You'll see more updates shortly. - There are multiple teams & efforts engaged in tracking & advocacy. More to come soon!

Dear trainee friends (et al.), 'Tis true that parts of the sky are falling & this is distracting. However, if you happen to have done A THING (paper, etc.), we want to support you. Don't hold back from letting us know. So we can learn and 👏. We're still here for the science. Sincerely, Everyone

ICYMI, NIH will be asking soon for each NIH-funded researcher to justify every draw they make (often several times a week) on their grants and every NIH officer and their boss will have to justify their agreeing on these draws. This is the death of US biomedical research by a thousand cuts

YES!!! There is no magical pot of money waiting in Europe for scientists fleeing the US. And it sure as 💩 isn't in Canada, which has been foolishly slashing university funding and all research funding for YEARS. NZ has recently started doing the same. A lot of science will just die on the vine.

Hey! Are you an American considering a PhD or a postdoc, and the funding / academic situation just went absolutely bonkers? Canada's federal funding awards just added eligibility for international applicants if at Cdn institutions. www.nserc-crsng.gc.ca/NewsDetail-D...

Couldn’t agree more!

New report shows that NIH grants fueled $95 billion in economic activity and 407,782 jobs in 2024. That's not to mention the countless lives that biomedical research has saved. Show me a better investment than that. www.forbes.com/sites/michae...

Some encouraging news on the NIH front. The NIA council meeting that was cancelled in January convened virtually in the last day or so and voted on pending grants. This should free up some Alzheimer’s funding.

👇🎯 The public isn't going to understand this, unless the presidents of R1 universities around the country <loudly> & <collectively> get out into the public square & start explaining this & calling out the existential threat to the entire 🇺🇸 university system. The silence is deafening right now.

But this move is a cut. We are hearing approximately 150 SROs will be removed, out of approximately 600. That's in line with Berg's numbers. Removing SROs will slow grant review, and that will reduce grant funding.

Preliminary injunction in nationwide indirect cost rate case. This means that the judge found that the plaintiffs (AAMC, et al.) are likely to win on the merits when the ruling is finalized. www.statnews.com/2025/03/05/n...

I got laid off today, with the rest of 18F. 18F was an elite federal software shop. We made gov't websites work better, more efficiently for the American people. We saved taxpayers from getting screwed over by contractors. And were fired for it. We made this website to tell our story: 18f.org