#Circadian #medicine tests if treatment timing can improve patient outcomes. This paper by @mariafelicita.bsky.social @oliviawalch.bsky.social et al considers #chronodiagnostics ...how the outcome of a standard test for glioblastoma differs with time of biopsy. link.springer.com/article/10.1...

I have been trying to get this published as an op-ed, but I am going to post it here since I think it is timely in light of the "consent" extortion events. Deafening Quiet from the Scientific Establishment jeremymberg.github.io/jeremyberg.g... 1/14

Interested in a tenure track position teaching and doing research with undergrads at a PUI? We are looking for a broadly-defined microbiologist who can teach Med Micro and Immunology. Apply at universityofscrantonjobs.com/postings/8308. Pls share widely to feeds (& on twitter if you still tweet)! 🦠

I am not a political pawn. I am a living, breathing human being who has dedicated her life to a scientific problem that I believe matters for human health. The article below tells our story; I hope you will read it and share it www.nytimes.com/2025/09/14/m...

Don't miss this opportunity to be our colleague! Very exciting initiative here at UVA!

Come be my colleague! Happy to answer any questions about what it's like living in Charlottesville and being in the department.

We welcome applicants working on: • Neural circuits & plasticity • Glia & brain interactions • Behavioral genetics & genomics …and more! Join a highly interdisciplinary department with access to state-of-the-art imaging, genomics, metabolomics, and computing resources.

At UVA, you’ll be part of a vibrant, collaborative neuroscience community spanning Biology, Medicine, Engineering, Data Science & more... in beautiful Charlottesville, VA. 🌄 Apply today & help shape the future of neuroscience: 👉 apply.interfolio.com/172892

🚨 We’re hiring! 🧪 @uvabio.bsky.social UVA Biology is recruiting multiple tenure-track Assistant Professors in neuroscience as part of a $75M Brain & Neuroscience Initiative. 🧠 Apply by Oct 15, 2025. Start Aug 2026. 👉 apply.interfolio.com/172892 #Neuroscience #FacultyJobs #NeuroJobs #Biology #UVA

🚨 We’re hiring! 🧪 @uvabio.bsky.social UVA Biology is recruiting multiple tenure-track Assistant Professors in neuroscience as part of a $75M Brain & Neuroscience Initiative. 🧠 Apply by Oct 15, 2025. Start Aug 2026. 👉 apply.interfolio.com/172892 #Neuroscience #FacultyJobs #NeuroJobs #Biology #UVA

It is impossible to explain to civilians how it feels to finally, FINALLY, land a clearly within-payline NIH grant score and then have it go unfunded because of all this regime bullshit. You all have my sympathies. Unfair doesn’t even begin to describe it.

GIP receptor agonism suppresses inflammation-induced aversion and food intake via distinct circuits https://www.biorxiv.org/content/10.1101/2025.08.12.669936v1

Sharing our newest study led by the incredibly talented @federicamosti.bsky.social investigating new molecular mechanisms of human brain development. We discover a human-specific enhancer HAR1984 that influences chromatin looping to promote cortical size and folding! www.biorxiv.org/cgi/content/...

These are the most challenging times for early-career scientists and engineers. My team is doing its bit to help by maintaining and even expanding our database of funding opportunities for early-career researchers. We found 437 of them. Download it freely here: research.jhu.edu/rdt/funding-...

My team has updated our free database of POSTDOC fellowships. This database contains 286 entries. For each entry, we provide a link, short description, deadline, amount, and eligibility criteria. Download this updated and expanded database here: research.jhu.edu/rdt/funding-...

The updated version of the database of PhD fellowships produced and maintained by my team can be downloaded by anyone here: research.jhu.edu/rdt/funding-... For each of the 187 fellowships, you will find a short description, deadline, $ amount, link, etc. Good luck!

It doesn't matter if the Executive Order is illegal. The NIH has demonstrated consistently that it will follow orders from the OMB. Expect immediate action from the NIH on this order. As I told you months ago, the old NIH is gone.

People who were overweight or had obesity lost a substantial amount of weight after taking a daily pill made by Eli Lilly, the company reported Wednesday. If the pill is approved by the FDA, it'll provide an alternative to weight-loss injectables like Ozempic.

"What struck me was that many of my colleagues at universities [last week] were like, ‘Oh, my God, they’re stopping grants!’ And it seemed to activate people in a way that I hadn’t seen before. Whereas a lot of us at NIH thought, ‘Oh, they just did another thing [to stop grants].’” 🧪

#JNeurosci: Stritzel et al. found that brief nighttime exposure to dim red light conditions widely used in rodent research caused circadian disruption and red light stimuli were detected by the rodent visual system. ‪@colorado.edu‬ @vulintus.com‬ https://doi.org/10.1523/JNEUROSCI.0157-25.2025

If they really had our backs, they would take steps RIGHT NOW to stop the NIH from continuing with the multi year mandate pushed by Vought and the OMB.

Metformin, the first line drug for Type 2 diabetes, has been used for 60 years without a clearcut mechanism of action. It turns out it's not just reducing glucose output from the liver. Metformin also works via the brain www.science.org/doi/10.1126/...

Houston researchers found that low-dose metformin needs Rap1 in the brain to lower blood sugar. Without brain Rap1, metformin doesn’t work, but other diabetes drugs still do. The ventromedial hypothalamus is the key control site. www.science.org/doi/10.1126/...

Blame the damn human not the poor mouse! open.substack.com/pub/zendudes...

Here's the provision to block multi-year funding: (the bill text PDF will later be updated with this as an adopted amendment: www.appropriations.senate.gov/imo/media/do...)

The bill is not posted but multiple sources tell me that it contains a provision that multi-year funding cannot exceed fiscal year 2024 levels. I will check as soon as it is posted.

Happening Now! Mark-up of Labor, Health, and Human Services www.appropriations.senate.gov/hearings/ful...

How do animals decide if they should forage for food or stay home to take care of newborn offspring? Whose needs come first? For my PhD work now out in Nature, we examined how hunger and parenting neurons interact and are reshaped postpartum in mice 🧵⬇️ www.nature.com/articles/s41...

I’m excited to share our work which identifies a new seminal fluid protein in C. elegans!

Grants at Columbia unfrozen at 9:30 this morning... Refrozen at 2:30 this afternoon with instructions to undo all of the releases done earlier. It like the 7th graders in detention broke into the Principal's Office...

For better or worse, these drugs seem to be making it deep into the brain. They’re poised to reshape the weight-management pharmaceutical landscape: time.com/7278429/weig... www.nytimes.com/2025/04/17/h...

Our updated preprint is live: A Brain Reward Circuit Inhibited by Next-Generation Weight Loss Drugs www.biorxiv.org/content/10.1... We developed humanized mouse models to test oral small-molecule GLP-1RAs, including one likely to hit the market in early 2026.🧪

This is chilling to watch and utterly unacceptable in the United States of America. As a former Senator, I’m calling on all current members to speak out on behalf of Sen. Padilla and defend him and the Senate against these outrageous attacks.

Stop this blatant violation of the Constitution’s system of checks and balances before it’s too late.

I helped explain to the Chicago Tribune the enourmous and irrational damage the NIH funding freeze is causing at Northwestern. “You’re at risk of losing an entire next generation of scientists" "it’s terrifying; it’s completely senseless." www.chicagotribune.com/2025/06/07/w...

Funding freeze at Northwestern from Emma Mairson at grant-watch.us. Data from USAspending. Normally, ~$70 M per month. Now, bupkis. Northwestern is keeping research moving and must be spending ~$40 M per month. Clearly not sustainable for too long.

"officials said Northwestern researchers have not received payments for National Institutes of Health grants since March, signaling that those funds have been frozen, despite no official word from the Trump administration."

Bleak is correct. And angry.

Cuts have consequences, illustrated. As seen on TV 📺

Mice lacking this amino acid lost 30% body weight www.nature.com/articles/d41... Am I missing something? Mice engineered to have a specific and severe defect in amino acid metabolism get sick and lose weight. Might the rush to find new weight loss targets be impairing our critical faculties ?

Disinformation straight from the White House.

CNN sucks.

America cannot long remain free, nor first among nations, if it becomes the kind of place where universities are dismantled because they don't align politically with the current head of the government.

Harvard filed a suit within 24 hours after the Noem visa-stripping. The judge issued a temporary restraining order less than 2 hrs later. The legal system CAN work quickly if the plaintiffs are prepared— know the judges and their courtroom rules, have strategy set and filings ready.

Proud of Harvard for pushing back, exercising some creativity, and, maybe, helping folks get some needed education. Harvard is making many of their online government courses FREE. I just signed up for "Citizen Politics in America". They even asked me my Gender. pll.harvard.edu/subject/gove...

All of NIH funding to Northwestern University is frozen. This pause includes noncompeting approved funding, new and competing grants with fundable scores. No reimbursements for money already spent have been received since March. This situation is rarely reported so please Please get the word out!

Senator Durbin noted that some (I believe Republican Senators) had indicated the US had been doing more than its share of biomedical research and it was time for other countries take a turn. I felt I had to interrupt to respond...