Maxime Caouaille
@mcaouaille.bsky.social
๐ค 84
๐ฅ 191
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PhD student in tuberculosis immunity
@ipbstoulouse.bsky.social
reposted by
Maxime Caouaille
Olivier Neyrolles
6 days ago
๐ฅณ ๐๐ฑ๐๐ข๐ญ๐๐ ๐ญ๐จ ๐ฌ๐ก๐๐ซ๐ ๐จ๐ฎ๐ซ ๐ฅ๐๐ญ๐๐ฌ๐ญ ๐ฐ๐จ๐ซ๐ค ๐ฌ๐ก๐จ๐ฐ๐ข๐ง๐ ๐ก๐จ๐ฐ ๐ฉ๐จ๐ฅ๐ฒ๐ฌ๐ข๐๐ฅ๐ฒ๐ฅ๐๐ญ๐ข๐จ๐ง, ๐ ๐ซ๐๐ซ๐ ๐ฉ๐ซ๐จ๐ญ๐๐ข๐ง ๐ฆ๐จ๐๐ข๐๐ข๐๐๐ญ๐ข๐จ๐ง, ๐ซ๐๐ ๐ฎ๐ฅ๐๐ญ๐๐ฌ ๐ข๐ง๐๐ฅ๐๐ฆ๐ฆ๐๐ญ๐จ๐ซ๐ฒ ๐ฆ๐จ๐ง๐จ๐๐ฒ๐ญ๐ ๐ฆ๐จ๐๐ข๐ฅ๐ข๐ณ๐๐ญ๐ข๐จ๐ง ๐๐ซ๐จ๐ฆ ๐ญ๐ก๐ ๐๐จ๐ง๐ ๐ฆ๐๐ซ๐ซ๐จ๐ฐ. โ๏ธ Aurรฉlien Boyancรฉ, Nelly Gilles,
@yoannrombouts.bsky.social
& coll.
@ipbstoulouse.bsky.social
๐
shorturl.at/IDwza
๐ A short thread...
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Maxime Caouaille
Bryan Bryson
about 1 month ago
Two pieces of fun news: 1. We've launched a new website for our lab:
www.brysonlab.org
2. With some new funding, we are recruiting for new postdocs and graduate students. The projects build upon our previous studies of antigen presentation and phagosome biology and go into new exciting dimensions!
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The Bryson Lab | Vaccine Development & Research at MIT
Developing effective accessible vaccines to end tuberculosis worldwide. Combining immunoengineering, molecular microbiology & systems biology at MIT.
https://www.brysonlab.org/
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reposted by
Maxime Caouaille
Olivier Neyrolles
about 1 month ago
๐จ ๐๐๐ฐ ๐ฉ๐ซ๐๐ฉ๐ซ๐ข๐ง๐ญ ๐๐ซ๐จ๐ฆ ๐จ๐ฎ๐ซ ๐ฅ๐๐, ๐๐ง๐ ๐ ๐๐ข๐ซ๐ฌ๐ญ ๐ข๐ง ๐ญ๐ก๐ ๐๐ ๐๐ข๐๐ฅ๐! ๐จ Weโre thrilled to share our new study revealing how the chromatin regulator SP140 preserves protective T cell immunity during
#tuberculosis
infection by restraining harmful type I IFN responses. ๐ ๐ฅ๐ฒ๐ฎ๐ฑ ๐๐ต๐ฒ ๐ฝ๐ฟ๐ฒ๐ฝ๐ฟ๐ถ๐ป๐:
shorturl.at/r5jd9
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reposted by
Maxime Caouaille
bioRxiv Immunology
about 1 month ago
SP140 limits type I interferon-driven pathology, preserving T cell motility and promoting resistance in tuberculosis
https://www.biorxiv.org/content/10.64898/2025.12.05.692491v1
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reposted by
Maxime Caouaille
IPBS Toulouse
about 2 months ago
IPBS researchers created LiveLung-TB, a BSL-3 imaging platform that visualizes real-time immune responses in Mtb-infected lungs. They found most CD4 T cells fail to reach infected cells, revealing physical barriers that limit TB immunityโa new window into host-pathogen dynamics! ๐ฌ๐ซ
#Tuberculosis
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reposted by
Maxime Caouaille
IPBS Toulouse
2 months ago
We are thrilled to congratulate
@lucianabalboa.bsky.social
, co-leader of our IPBS/CNRS-CONICET lab, for receiving a special mention in the LโOrรฉal-UNESCO โFor Women in Scienceโ Award 2025. This honor recognizes her exceptional career & dedication to research in infectious diseases.
shorturl.at/Gfo4a
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reposted by
Maxime Caouaille
Olivier Neyrolles
4 months ago
Excited to share Wendy Le Mouรซllicโs PhD work, now published in
@pnas.org
! It reveals that M. tuberculosis depends on inorganic sulfate import to survive inside host cellsโfueling essential processes such as redox balance and stress resistance. Huge congrats to Wendy & colleagues!
shorturl.at/WbFQC
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Inorganic sulfate is critical for Mycobacterium tuberculosis lung tissue colonization and redox balance | PNAS
Tuberculosis remains the deadliest infectious disease caused by a single pathogen, highlighting the urgent need for novel therapies. A deeper under...
https://www.pnas.org/doi/10.1073/pnas.2503966122
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reposted by
Maxime Caouaille
Olivier Neyrolles
7 months ago
Thrilled to have co-authored this review with amazing colleagues! We dive into the mysteries of T cell immunity in TB and explore how cutting-edge tech could unlock better vaccines.
#Tuberculosis
#Immunology
#TCells
#Vaccines
@natrevimmunol.nature.com
www.nature.com/articles/s41...
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Finding and filling the knowledge gaps in mechanisms of T cell-mediated TB immunity to inform vaccine design - Nature Reviews Immunology
T cells have an essential role in immune responses to Mycobacterium tuberculosis, but the mechanisms by which they may provide protective immunity remain poorly understood. This Review explores the kn...
https://www.nature.com/articles/s41577-025-01192-z
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reposted by
Maxime Caouaille
Pierre Dupuy
7 months ago
After a PhD and two postdocs, Iโm very proud to be joining the CNRS as a Chargรฉ de recherche, this is a meaningful milestone. Huge thanks to Claude Bruand,
@michaelglickman.bsky.social
, and
@oneyrolles.bsky.social
for their guidance and support. Olivier, letโs turn this into exciting discoveries!
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reposted by
Maxime Caouaille
IPBS Toulouse
8 months ago
In
@cp-cellrepmed.bsky.social
, IPBS researchers propose a treatment based on optimized antibodies that, in mice, increases the proportion of HEV blood vessels and facilitates killer cell entry into tumors. These molecules are currently in clinical trials โคต๏ธ
buff.ly/Ip3US2l
add a skeleton here at some point
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reposted by
Maxime Caouaille
Olivier Neyrolles
10 months ago
Shout-out to
@pierredupuy.bsky.social
and colleagues! Excited to share our latest study, where we uncovered a previously unknown bacterial defense system in M.
#tuberculosis
: effluxosomes โ dynamic membrane clusters that coordinate resistance to multiple toxic metals.
shorturl.at/Ek0HD
#MicroSky
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reposted by
Maxime Caouaille
IPBS Toulouse
10 months ago
Comment la bactรฉrie responsable de la tuberculose survit-elle aux attaques des cellules immunitaires ? ๐ฆ Pierre Dupuy, laurรฉat dโune bourse postdoctorale Marie-Curie financรฉe par lโUE, revient sur son projet.
@cnrsbiologie.bsky.social
@cnrs.fr
@isabellesaves.bsky.social
@oneyrolles.bsky.social
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reposted by
Maxime Caouaille
Paul Cohen
10 months ago
Le Monde reporting that a French scientist traveling to Houston to attend a conference was denied entry to US after a search of his phone & computer revealed messages critical of Trump's science cuts, "which [says CPB] conveyed hatred of Trump & could be qualified as terrorism". Computer confiscated
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reposted by
Maxime Caouaille
Olivier Neyrolles
10 months ago
Excited to share our last study. Huge congrats to Sarah Monard, Arnaud Mรฉtais,
@gclugo.bsky.social
,
@chrisverollet.bsky.social
and all colleagues! We have found a mysterious cell type inside TB lung lesions that seems neuron-like but isn't quite a nerve cell. Let's dive in๐
shorturl.at/x4Sb5
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reposted by
Maxime Caouaille
bioRxiv Immunology
10 months ago
Identification of a unique TUBB3+ cell population in the tuberculosis granuloma
https://www.biorxiv.org/content/10.1101/2025.03.04.641465v1
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reposted by
Maxime Caouaille
IPBS Toulouse
11 months ago
Santรฉ et changement climatique. Une mystรฉrieuse maladie cutanรฉe a frappรฉ plus de 1000 pรชcheurs sรฉnรฉgalais en 2020-2021. Des chercheurs de lโIPBS et leurs collรจgues rรฉvรจlent enfin la cause dans
@embomolmed.org
: une toxine dโune microalgue marine dรฉclenche une inflammation sรฉvรจre.
shorturl.at/VCcRg
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ยซ La mystรฉrieuse maladie des pรชcheurs sรฉnรฉgalais ยป : la coupable est une microalgue marine toxique - IPBS-Toulouse
Pรชcheurs au retour de pรชche, langue de Barbarie. Saint-Louis / Sรฉnรฉgal โ Crรฉdits : IRD,[โฆ]
https://shorturl.at/VCcRg
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reposted by
Maxime Caouaille
MGilleron
12 months ago
These IPBS researchers have given fantastic talks at Les Diablerets european meeting !
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reposted by
Maxime Caouaille
Olivier Neyrolles
about 1 year ago
๐Thrilled to announce the 10th anniversary of the
@ipbstoulouse.bsky.social
Student Symposium in Toulouse, Nov. 4-5! Honored to welcome stellar keynote speakers Y. Belkaid,
@mblokesch.bsky.social
, F. Mechta-Grigoriou, and B. Kรผster - A celebration of science & discovery!
www.ipbs.fr/agenda/event...
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reposted by
Maxime Caouaille
Olivier Neyrolles
about 1 year ago
๐ Congrats to Dr. Wendy Le Mouรซllic on crushing her PhD defense! Another viva victory for the lab ๐งช๐
#PhDone
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reposted by
Maxime Caouaille
Olivier Neyrolles
about 1 year ago
๐ Thrilled to share the first paper by
@saurabhchugh09.bsky.social
, a talented Marie Skลodowska-Curie fellow in our lab! Discover how the exometabolome acts as a hidden driver of bacterial virulence and pathogenesis
#MicroSky
@cp-trendsmicrobiol.bsky.social
www.sciencedirect.com/science/arti...
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The exometabolome as a hidden driver of bacterial virulence and pathogenesis
The traditional view of metabolism as merely supplying energy and biosynthetic precursors is undergoing a paradigm shift. Metabolic dynamics not only โฆ
https://www.sciencedirect.com/science/article/pii/S0966842X24003123
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reposted by
Maxime Caouaille
Carolyn King
about 1 year ago
Speaker line up for
#EMBOTissueImmunity
to take place in Basel ๐จ๐ญ 26-29 August 2025. Come join
@maurogaya.bsky.social
and I for some fantastic
#immunology
along the Rhine! Please share this invitation - we hope you will join us. Registrations will be open soon.
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