🥳 𝐄𝐱𝐜𝐢𝐭𝐞𝐝 𝐭𝐨 𝐬𝐡𝐚𝐫𝐞 𝐨𝐮𝐫 𝐥𝐚𝐭𝐞𝐬𝐭 𝐰𝐨𝐫𝐤 𝐬𝐡𝐨𝐰𝐢𝐧𝐠 𝐡𝐨𝐰 𝐩𝐨𝐥𝐲𝐬𝐢𝐚𝐥𝐲𝐥𝐚𝐭𝐢𝐨𝐧, 𝐚 𝐫𝐚𝐫𝐞 𝐩𝐫𝐨𝐭𝐞𝐢𝐧 𝐦𝐨𝐝𝐢𝐟𝐢𝐜𝐚𝐭𝐢𝐨𝐧, 𝐫𝐞𝐠𝐮𝐥𝐚𝐭𝐞𝐬 𝐢𝐧𝐟𝐥𝐚𝐦𝐦𝐚𝐭𝐨𝐫𝐲 𝐦𝐨𝐧𝐨𝐜𝐲𝐭𝐞 𝐦𝐨𝐛𝐢𝐥𝐢𝐳𝐚𝐭𝐢𝐨𝐧 𝐟𝐫𝐨𝐦 𝐭𝐡𝐞 𝐛𝐨𝐧𝐞 𝐦𝐚𝐫𝐫𝐨𝐰. ✍️ Aurélien Boyancé, Nelly Gilles, @yoannrombouts.bsky.social & coll. @ipbstoulouse.bsky.social 📖 shorturl.at/IDwza 👇 A short thread...

Two pieces of fun news: 1. We've launched a new website for our lab: www.brysonlab.org 2. With some new funding, we are recruiting for new postdocs and graduate students. The projects build upon our previous studies of antigen presentation and phagosome biology and go into new exciting dimensions!

🚨 𝐍𝐞𝐰 𝐩𝐫𝐞𝐩𝐫𝐢𝐧𝐭 𝐟𝐫𝐨𝐦 𝐨𝐮𝐫 𝐥𝐚𝐛, 𝐚𝐧𝐝 𝐚 𝐟𝐢𝐫𝐬𝐭 𝐢𝐧 𝐭𝐡𝐞 𝐓𝐁 𝐟𝐢𝐞𝐥𝐝! 🚨 We’re thrilled to share our new study revealing how the chromatin regulator SP140 preserves protective T cell immunity during #tuberculosis infection by restraining harmful type I IFN responses. 📖 𝗥𝗲𝗮𝗱 𝘁𝗵𝗲 𝗽𝗿𝗲𝗽𝗿𝗶𝗻𝘁: shorturl.at/r5jd9

SP140 limits type I interferon-driven pathology, preserving T cell motility and promoting resistance in tuberculosis https://www.biorxiv.org/content/10.64898/2025.12.05.692491v1

IPBS researchers created LiveLung-TB, a BSL-3 imaging platform that visualizes real-time immune responses in Mtb-infected lungs. They found most CD4 T cells fail to reach infected cells, revealing physical barriers that limit TB immunity—a new window into host-pathogen dynamics! 🔬🫁 #Tuberculosis

We are thrilled to congratulate @lucianabalboa.bsky.social, co-leader of our IPBS/CNRS-CONICET lab, for receiving a special mention in the L’Oréal-UNESCO “For Women in Science” Award 2025. This honor recognizes her exceptional career & dedication to research in infectious diseases. shorturl.at/Gfo4a

Excited to share Wendy Le Mouëllic’s PhD work, now published in @pnas.org! It reveals that M. tuberculosis depends on inorganic sulfate import to survive inside host cells—fueling essential processes such as redox balance and stress resistance. Huge congrats to Wendy & colleagues! shorturl.at/WbFQC

Thrilled to have co-authored this review with amazing colleagues! We dive into the mysteries of T cell immunity in TB and explore how cutting-edge tech could unlock better vaccines. #Tuberculosis #Immunology #TCells #Vaccines @natrevimmunol.nature.com www.nature.com/articles/s41...

After a PhD and two postdocs, I’m very proud to be joining the CNRS as a Chargé de recherche, this is a meaningful milestone. Huge thanks to Claude Bruand, @michaelglickman.bsky.social, and @oneyrolles.bsky.social for their guidance and support. Olivier, let’s turn this into exciting discoveries!

In @cp-cellrepmed.bsky.social, IPBS researchers propose a treatment based on optimized antibodies that, in mice, increases the proportion of HEV blood vessels and facilitates killer cell entry into tumors. These molecules are currently in clinical trials ⤵️ buff.ly/Ip3US2l

Shout-out to @pierredupuy.bsky.social and colleagues! Excited to share our latest study, where we uncovered a previously unknown bacterial defense system in M. #tuberculosis: effluxosomes — dynamic membrane clusters that coordinate resistance to multiple toxic metals. shorturl.at/Ek0HD #MicroSky

Comment la bactérie responsable de la tuberculose survit-elle aux attaques des cellules immunitaires ? 🦠 Pierre Dupuy, lauréat d’une bourse postdoctorale Marie-Curie financée par l’UE, revient sur son projet. @cnrsbiologie.bsky.social @cnrs.fr @isabellesaves.bsky.social @oneyrolles.bsky.social

Le Monde reporting that a French scientist traveling to Houston to attend a conference was denied entry to US after a search of his phone & computer revealed messages critical of Trump's science cuts, "which [says CPB] conveyed hatred of Trump & could be qualified as terrorism". Computer confiscated

Excited to share our last study. Huge congrats to Sarah Monard, Arnaud Métais, @gclugo.bsky.social, @chrisverollet.bsky.social and all colleagues! We have found a mysterious cell type inside TB lung lesions that seems neuron-like but isn't quite a nerve cell. Let's dive in👇 shorturl.at/x4Sb5

Identification of a unique TUBB3+ cell population in the tuberculosis granuloma https://www.biorxiv.org/content/10.1101/2025.03.04.641465v1

Santé et changement climatique. Une mystérieuse maladie cutanée a frappé plus de 1000 pêcheurs sénégalais en 2020-2021. Des chercheurs de l’IPBS et leurs collègues révèlent enfin la cause dans @embomolmed.org : une toxine d’une microalgue marine déclenche une inflammation sévère. shorturl.at/VCcRg

These IPBS researchers have given fantastic talks at Les Diablerets european meeting !

🎉Thrilled to announce the 10th anniversary of the @ipbstoulouse.bsky.social Student Symposium in Toulouse, Nov. 4-5! Honored to welcome stellar keynote speakers Y. Belkaid, @mblokesch.bsky.social, F. Mechta-Grigoriou, and B. Küster - A celebration of science & discovery! www.ipbs.fr/agenda/event...

🎉 Congrats to Dr. Wendy Le Mouëllic on crushing her PhD defense! Another viva victory for the lab 🧪🎓 #PhDone

🎉 Thrilled to share the first paper by @saurabhchugh09.bsky.social, a talented Marie Skłodowska-Curie fellow in our lab! Discover how the exometabolome acts as a hidden driver of bacterial virulence and pathogenesis #MicroSky @cp-trendsmicrobiol.bsky.social www.sciencedirect.com/science/arti...

Speaker line up for #EMBOTissueImmunity to take place in Basel 🇨🇭 26-29 August 2025. Come join @maurogaya.bsky.social and I for some fantastic #immunology along the Rhine! Please share this invitation - we hope you will join us. Registrations will be open soon.