So proud to see this story finally out!🎉 We added new data since our previous preprint—transgenic barley plants with an engineered immune receptor that fights off two fungal pathogens at once. Short 🧵 and link to the original preprint thread on X👇 www.science.org/doi/10.1126/...

📢 PDRA Position - Plant Immune Receptor Bioengineering at Imperial College London 🌱 Start: Aug 2026 (flexible) 🧪 Wet lab + bioinformatics 📅 Up to 3 years (ERC-funded) 📍 South Kensington, on site ℹ️ shorturl.at/VIITk 🔗 kourelislab.com #PlantImmunity #PlantPathology 🙏 Share with interested candidates!

Preprint Alert 🚨 @philcarella.bsky.social lab stepping into TIR-ritory!! Project started by me but finished by talented PhD student @ebkennedy.bsky.social (Please follow her), with contribution from Zhao He and @jonathandgjones.bsky.social We investigated EDS1-dependency of TIR domain. See thread👇

Check out our latest pre-print on the evolution of TIR activity/signalling: www.biorxiv.org/content/10.6...

@khongsamchia.bsky.social Extremely excited to share the first pre-print from my PhD project in the Carella lab, co-first authored with @khongsamchia.bsky.social 🎉 (Thread below ⬇️) www.biorxiv.org/content/10.6... Huge thanks to all co-authors and the #CarellaCapybaras for all the support 😊

Finally made it.... congratulations all.

End of April and I got my diploma🥂 Now the PhD degree is official! I hope I've mentioned everyone in my acknowledgments, but I still can’t thank you enough for all the support along this journey: ) If anyone's looking for some 400-page light reading… here it is ➡️ ueaeprints.uea.ac.uk/id/eprint/10...

Fun thread. Cool work, and make sure to read all the way to the end!

New Preprint in collaboration with GoogleDeepMind: AI-guided discovery of atypical protein assemblies The @kamounlab.bsky.social discovered an 11-protomer complex thanks to the Structural Novelty Index , a new way to use AlphaFold to find protein assemblies that break the pattern.

Just published: Breaking the Pattern with AlphaFold: Introducing the Structural Novelty Index AlphaFold has transformed how we predict protein structures. But sometimes most interesting discoveries come from asking a different question: which proteins break the pattern? medium.com/p/breaking-t...

Some predictions are high-confidence. These go to eleven! Huge congrats to the whole team ❤️ Such a privilege to work with you all.

UP TO ELEVEN - We expressed potato NRC7, imaged it by negative-stain EM, ran 2D classification. 🔬💥 Rings ~250 Å across — way bigger than canonical hexamers (~150 Å). 11 protomers. (5/n)

AI-guided discovery of atypical protein assemblies https://www.biorxiv.org/content/10.64898/2026.05.03.722499v1

AI-guided discovery of atypical protein assemblies https://www.biorxiv.org/content/10.64898/2026.05.03.722499v1

Excited to share our latest work on plant immune receptor biochemistry! @kamounlab.bsky.social @hsuanpai.bsky.social @mpcontreras.bsky.social Jose Salguero Linares @danielluedke.bsky.social @adnroide.bsky.social @jiorgoskourelis.bsky.social www.biorxiv.org/content/10.6...

1/10 We are thrilled to share our preprint on spatial transcriptomics in wheat spikes led by the amazing @katielong.bsky.social and Ashleigh Lister. We resolved expression of 200 genes to cellular resolution. Pre-print👉 tinyurl.com/c7t3kncf., @johninnescentre.bsky.social @earlhaminst.bsky.social

Many academics point to bioRxiv as “the one thing improving science publishing”. If so, the one thing you all can do is persuade colleagues to submit and make this a norm. 1/2

Germany's ZB MED signs publishing partnership agreement with MDPI. At a time when MDPI is considered predatory to most, this is a baffling move. 🤑🤢 Doesn't reflect good on #BioMedicalResearch in Germany. www.mdpi.com/about/announ... #SciPub #ScientificPublishing #PredatoryPublishers #OpenAccess

From predoc to postdoc… The legendary Nef @NeftalyCM 🇲🇽 is moving on for some Swiss adventures! Thank you Nef for all your contributions to @TheSainsburyLab science and way beyond… What a gentleman! #CelebratingAlumni

Very pleased to have passed my PhD viva today! Thank you Núria and @jonathandgjones.bsky.social for serving as my examiners and to Wenbo for your supervision and guidance! Has been a really great experience at @thesainsburylab.bsky.social! Photo courtesy of @stephbornemann.bsky.social

Huge congratulations to @draegermarkus.bsky.social for passing his viva today @thesainsburylab.bsky.social. Thank you for @saskiahogenhout.bsky.social and Julia Santiago acting as examinars. #Veryproudsupervisor!

HI old friends! Finally took the leap here to say I have several open positions going in my lab at the moment (and more to come). 1) PhD studentship in collaboration with the Royal Horticultural Society (genomics) 2) Biochemistry Postdoc to understand how Starships move Check out the links below!

📢 PhD Opportunity in my lab on Plant Immune Receptor Bioengineering at @imperiallifesci.bsky.social 🌱 Start: October 2025 📅 Deadline: 12th January 2025 🇬🇧 Open to UK students 💰 Fully funded ℹ️ More info: tinyurl.com/w6ap9v9f ❗ #PlantImmunity #PlantPathology 🙏 Please share with interested candidates!

Is this not the finest lab crafted Christmas tree decoration you’ve ever seen? Courtesy of Amy Tooke!

Several Jedis in our lab joined forces to review the rise of the plant immune resistance at DNA, RNA, and protein levels 💫🚀 check out the preprinted review here: zenodo.org/records/1420...

Excited to share the fruits of my PhD! www.biorxiv.org/content/10.1...

NEW!!! Can AI distinguish between sensor and helper NLRs? #NLRbiology 👇🏼

A root-specific NLR network confers resistance to plant parasitic nematodes https://www.biorxiv.org/content/10.1101/2023.12.14.571630v1

We’re speaking at the @TheSainsburyLab Autumn Symposium 🙏 getgenome.net/impact

Our work on a Phytophthora WY effector that hijacks a host is now out in MPMI! Check it out here: doi.org/10.1094/MPMI...

Great time at the TSL student/postdoc pumpkin carving social today! 🎃 📸 by Matt Wengler