Yes, Swiss scientist Fritz Zwicky coined the term “dark matter” which is impressive, but he also coined the term “spherical bastard” to describe people who are bastards no matter which way you look at them, and I think that should be celebrated more.

Great interview here with @kauralasoo.bsky.social on genetics research and collaborative science. blog.cs.ut.ee/2025/10/06/k...

Every system that was regulated, either explicitly or implicitly, by the fact that they were effortful for humans (letters of recommendation, government filings, essays, or, as this paper finds, lawsuits) will break under a wave of AI.

Renewable energy generation exceeded rise in global electricity demand in 2025 Output from solar rose by a third while electricity from fossil fuels fell. www.theguardian.com/environment/...

I've been vegetarian most of my life, vegan off and on. A fact I usually keep to myself. But please, go ahead and scold me about AI and water usage between bites of your burger 🤌

Unclear why they'd do this.

Turns out that the usual NtHash is not as random as one might think?!?! At least not for minimizers. Seq-hash (and simd-minimizers) already has this fixed by default ;) github.com/rust-seq/seq...

New blog post! I use ntHash all the time to hash k-mers, yet it turns out it has some unexpected flaws (collision propagation, bias on leading zeros...). The good news: each of them can be fixed! igor.martayan.org/posts/breaki...

Almost half of EU’s busiest flight routes are ‘hard or impossible’ to book on trains – report

I was investigating the genomes that I didn't manage to convert to near-complete MAGs in my assembly graph (the components in gray). The circle on top left is actually a complete genome but with 40% completeness (both in metaMDBG and myloasm)

The genome of the hepatitis D virus, with just 1700 bases of RNA, was squeezed onto a quantum computer. Learn more: https://scim.ag/4mCifuv

Amazing work, as always, from @ale-campa.bsky.social! Now you can index AllTheBacteria v2 (sans dustbin and unknown) in only 130G. It’s always a pleasure to work with @jermp.bsky.social and @ale-campa.bsky.social, and I’m very excited for where Fulgor is going next!

Two more days to submit your abstract for a short talk or poster at RECOMB-Seq 2026. See instructions at recomb-seq.github.io/seq2026/call...

With @jermp.bsky.social & @robp.bsky.social, we have just released Fulgor v4.1.0 (also on bioconda! bioconda.github.io/recipes/fulg...). Here's what's new, and what's to come. 🧵 (1/6)

Don't be shy to take on a little two-week side project. These five months will be the most precious three years of your academic journey.

hilarious side effect here: execs getting advice from models whose training data is skewed specifically toward *failed businesses*

This is from 7 years ago (merenlab.org/2019/02/24/f...). We are talking about the same things today. We will be talking about the same things 7 years from now. There is no one to blame for this apart from ourselves. I find it very depressing.

Agree with this great thread as a whole. However in my niche where the search space is gargantuan LLM can implement and try an explosive amount of solution. Then the human only has to focus the interesting ones (a very tiny subset) according to a (non LLM) benchmark

With all the cuts to research funding in European countries, everyone is turning to the ERC... The ERC should be a source of supplementary funding, not a substitute. Every country in Europe must invest in basic research and increase its budgets!!!!

ERC : "We're overwhelmed with funding request, it's becoming unmanageable. We need to find a way to reduce the number of applications." French Government: "You need to go get the money from Europe, you bunch of losers!" 🫣

bIvangpu' 'e' yIvangQo'!

Rust 1.95! * IF-LET GUARDS; LFG!!!! * compile-time `cfg_select!` * a bunch of stabilizations blog.rust-lang.org/2026/04/16/R...

Are review papers in the scope of the SPIRE conference?(asking for a friend)

🧬 Preprint update with @worm-lab.bsky.social ! If you are aiming for a phased assembly, should you sequence @pacbio.bsky.social HiFi or @nanoporetech.com R10 reads? Whichever you have easier access to! The real question is: which assembler should you use based on your data? (1/2) #genomes

Data generated by AI models can contain subliminal signals that ‘teach’ other LLMs particular traits and biases go.nature.com/483Kkor

Fast and accurate multiple-protein-sequence alignment at scale with FAMSA2 www.nature.com/articles/s41... 🧬💻🧪 rdcu.be/fdw40

Quantum mechanics has gone from a theory in test to becoming the foundation of new technologies. Learn more in a 2025 #SciencePerspective that looked at 100 years of quantum mechanics: https://scim.ag/3Qvgi6M

10 years after the first FAMSA paper, its successor is now published in Nat Biotech! We believe that FAMSA2 can enable analyses of large protein collections that were previously unattainable. Thank you, Andrzej and Cedric, for great collaboration www.nature.com/articles/s41...

including Laurence J. Peter, whose version “Competition in academia is so vicious because the stakes are so small” I used above.

The fate of academic careers is decided in the dark, and the process is political, not based on merit or reason (“so vicious precisely because the stakes are so small”). AI is a black box? Come on... I’m a million times more afraid of humans than I am of AI, and in academia that’s doubly true.

I think the greatest barrier to worker solidarity in academia is the fact that faculty are constantly groomed to see themselves as exceptional and extraordinary. As such they are loath to accept that in comparison to the vast corpus of their peers they are perhaps less unique than they might think

Scientists have long pulled DNA from water and soil, but they have only just started to see the air as a source of genetic information go.nature.com/4suCiwd

@ksahlin.bsky.social any news about the Recomb-Seq reviews?

A worker died at an Amazon warehouse in Oregon last week. For more than an hour, workers were instructed to continue working as the man lay dead. One worker wanted to help, but a manager told them to “Just turn around and not look. Let’s get back to work," according to @thewesternedge.bsky.social.

Accepted to ISMB'26. Revised paper is here: jermp.github.io/assets/pdf/p.... I'd like to thank @robp.bsky.social once again and all the received feedback from the reviewers. To me, ISMB has had the highest quality review process over the past few years!

All elementary functions from a single binary operator arxiv.org/abs/2603.21852 Amusant !

I don't think anybody who played DF would argue XD

Really nice read!

I kept being rate limited by doi2bib, so I made a small CLI to replace it locally: github.com/imartayan/bi... It can output bibtex from DOIs and arxiv/biorxiv links, redirect to the published version when it's available and copy the result to your clipboard

What proportion of the sunflower genome has an indel in at least one individual? Basically all of it -- there's almost no sequence (at least at the 100kb window scale) found in all sunflowers!

‼️ Collaboration Métal Hurlant & SFBI dans le cadre de l'ADN dans tous ses états 📍Projet collaboratif unique pour rendre la recherche accessible et captivante dans un numéro spécial où science et art se rencontrent ℹ️ Infos : www.sfbi.fr/blog/article... ⏳ Date limite de soumission : 22 avril 2026

It strikes me that the legal situation for completely AI-generated code is not discussed more among open source developers?! The situation seems way more complicated than most folks seem to realize! chatgpt.com/share/69d78f...

Modern DRAM is based on a brilliant design from IBM. But, we're still paying for a latency penalty that's existed since the 60s! In this video, I'm introducing my research project (Tailslayer) that immensely reduces p99.99 latency on traditional RAM!

Your freezer is lying to you. 🥶 We found frozen samples picked up way more artifactual C>T mutations than DNA stored at room temp. The data surprised us. 🧬👇

To simplify, we began hosting a web page to index and simplify tracking RECOMB papers and their preprints and journal versions at recomb.org/proceedings/ This page serves as a central directory for all RECOMB publications.

Just crazy how good @typst.app is

WHAT