We all learnt from each other and it was real pleasure working together to understand GAPMs in plasmodium.

New preprint! Really excited to share our spatial proteomic study on Plasmodium falciparum schizonts . We used hyperLOPIT to map thousands of proteins—from apical invasion organelles to the infected red blood cell surface.

A huge thank you to all my co-authors for this great collaboration! @ritatewari.bsky.social @davidguttery.bsky.social @zeeshanm.bsky.social @eelcotromer.bsky.social

“The idea that taking walks, reading things unrelated to your research, and hanging out with strangers in a campus pub should be considered part of the serious process of thinking, but might well meet with skepticism in practice.” www.pnas.org/doi/10.1073/...

Many congratulations Ryuji. Your first paper on Plasmodium biology. Well done.

Happy Holi from our lab. Festival of colours. This to welcome the spring which I hope is round the corner.

📸 No one follows more etiquette rules than the Royal Family—but notice how King Charles didn’t make any smart-ass or demeaning comments about Zelensky’s attire today. Why? Because respect isn’t about clothes—it’s about character. And that’s something money can’t buy.

The Nikon AX-NSPARC demo is gearing up at the @ncis-marseille.bsky.social! Starting for #FluorescenceFriday with a large field-of-view confocal #cellfie of COS cells labeled for actin ⚫ endoplasmic reticulum 🟡 mitochondria 🔴 and nucleus 🔵. Fluorescence microscopy is also nice in inverted colors 🌈🧪

The world is full of crazy and sad news, but here is a protein that localizes to only one of the two flagella

Plastids & mitochondria arose from separate endosymbioses of prokaryotes.Their prokaryotic ancestry makes them susceptible to antibiotics. Antibiotics kill pathogenic protists by targeting their plastids or mitochondria. Here we review the lop sided inheritance. journals.plos.org/plospathogen...

The next GRC on volume Electron Microscopy is coming soon. Don't miss this opportunity and apply now as the number of seats is limited. #volumeEM www.grc.org/volume-elect... As I am new to bsky, please share widely (do we still say retweet?). 🙏

Many congratulations Richard and team. Great story on DNA replication.

A couple of weeks left to apply to join Development's *Pathway to Independence* programme Support & mentoring for post-docs on the academic job market Deadline: January 31 journals.biologists.com/dev/pages/pi...

What started out as chromosome-counting blossomed into an exciting tale of evolution at the interface between the volatile centromere and the reliable, stable cell division machinery - the latest from the brilliant Jana Helsen, now looking to start her own group! W/ @gsherloc.bsky.social 🧪🌎

If you’re thinking of what meeting to go to this year then check out the #phosphatase meeting in Würzburg. Lots of great speaking slots and events for junior researchers. It’s always a fun meeting meetings.embo.org/event/25-pho...

New discovery from our #CDlab reported in Cell @cp-cell.bsky.social today: SMC motor proteins have a left-right ‘gearbox’ and can switch direction in DNA loop extrusion! www.sciencedirect.com/science/arti... 1/

DNA replication beyond the cores of megabase chromosomes of T. brucei -- some of my PhD work is FINALLY out! doi.org/10.1038/s414... thank you to @rmc9z.bsky.social @marquescata.bsky.social Emma, Dario, Kathryn, Graham and Craig!

Delighted to share our first manuscript on @bsky.app on a novel SUN1-ALLAN complex in Plasmodium MTOC and NE organization. Many thanks @zeeshanm.bsky.social; @eelcotromer.bsky.social; @ryanase.bsky.social ; Tony; Sarah; David F; Karine; Igor; Cyrille; Declan. Link: www.biorxiv.org/content/10.1...

Here we are! To celebrate our arrival, here is a #trypanosome expanded ~13 times & stained for tubulin, individual cortical #microtubules can be recognised, what was only achievable by EM before. Images: Christine Girard-Blanc & Thierry Blisnick. Many thanks to @centriolelab.bsky.social for training

"Any pleasure I may take in the distinction of [being a Royal Society fellow] is diminished by the fact it is shared with someone who appears to be modelling himself on a Bond villain" www.researchprofessionalnews.com/rr-news-uk-c...

Cryptosporidium is an important public health threat, and it deserves better genetic tools to study it! Here we’ve developed a targeted in vivo CRISPR genetic screen to identify parasite genes required for survival and virulence… www.biorxiv.org/content/10.1...

I like this plan from EupathDB - No paywall 😀. We can volunteer to pay a fee from lab budgets. And a "mortgage calculator" tool coming up in Jan to guide us estimate that fair price based on several variables like lab size and usage. youtu.be/aSS6fiGVBG4?...

"Given the current political reality and the expansion of attacks on science, it is time for scientists to be more effective, forceful, and vociferous as their own political advocates." 🧪 www.science.org/doi/10.1126/...

Check out our new paper showing that male gametocytes need an active mitochondrion for gametogenesis: www.nature.com/articles/s42... Also, we have a big plug for our excellent new antibody marker specific for male gametocytes and gametes. @lshtm.bsky.social🧵

New preprint from others in the lab - Mapping origins of DNA replication in Leishmania. Great work Jeziel, Gabriel, @marquescata.bsky.social, Marija, Craig, Dario and the boss! www.biorxiv.org/content/10.1...

Only two weeks to go to the UK Vector-Borne Diseases meeting in Liverpool (3-4th December). We are full and there is no further registration for in-person attendance. Therefore, we have opened up online attendance - see here if interested. @baylism.bsky.social payments.liv.ac.uk/conferences-...

New preprint! How do cells rewire chromosome segregation during meiosis? We identify a germline-specific mRNA splice isoform for a critical kinetochore protein. This alternative protein transforms its regulatory control, contributing to proper fertility. www.biorxiv.org/content/10.1...

Official website for EMBO meiosis 2025 is live now! Looking forward to seeing you in Switzerland next June! #meiosis4eva meetings.embo.org/event/25-mei...