Do you want to learn essential GIBA concepts and techniques? We're hosting three mornings of expert-led sessions on gut, immune and brain research, from 23-26 March 📢🌟 🆓 Open to all across the GIBA Network 📅 Register by 13 March! 🔗 giba-uk.org/events/the-g...

🔬 New insights from gut-immune-brain research 🌟 A study with our network's @alexmsalmeida.bsky.social uncovers a "hidden” gut bacterial group found in higher levels in healthy people. Could this be key to microbiome health and future probiotic innovation? 🌍🦠 www.newscientist.com/article/2514...

Congratulations to @alexmsalmeida.bsky.social and his research team at the @camvetschool.bsky.social on their latest paper exploring the ‘hidden’ microbes in our gut. Discover more about their fascinating findings on the University of Cambridge Research website 👇🏽 www.cam.ac.uk/research/new...

Is there a missing link in our gut health? 🦠 New research from Alexandre Almeida’s lab has uncovered a ‘hidden group’ of bacteria - known as CAG-170 - that appears to be an indicator of human health. Read the full story: www.cam.ac.uk/research/new... @alexmsalmeida.bsky.social

I still find it mad that even though pretty much everyone now knows what a gut microbiome is and might think we have a pretty good idea of what's going on in there, we still don't have much clue about the majority of species in our guts, saying they are part of the "hidden microbiome"

The original research was published today in Cell Host & Microbe www.cell.com/cell-host-mi...

Thanks to @chrisnsimms.bsky.social and the @newscientist.com for covering our new work on the uncultured microbiome in @cp-cellhostmicrobe.bsky.social. It was great chatting more about the implications of our findings!

Great work again from @alexmsalmeida.bsky.social et al highlights uncultured genus CAG-170 (Oscillospiraceae) to be central node in healthy co-abundance networks in >11k gut metagenomes, with predicted B12 biosynthesis/cross-feeding functions possibly involved. www.sciencedirect.com/science/arti...

Excited to share the newest paper from our team, where we uncovered a potential role of the uncultured gut #microbiome in health: www.cell.com/cell-host-mi.... Out now in @cp-cellhostmicrobe.bsky.social @cellpress.bsky.social. With Ana C. da Silva, Jacob Lapkin, Qi Yin and Efrat Muller.

Our team wrote a review for Gut Microbes on the role of the gut #microbiome in modulating enteric infections. Great team effort by Qi Yin, @samriddhigupta.bsky.social and Efrat Muller: www.tandfonline.com/doi/full/10....

Excited to be speaking at this ECR Symposium in Nottingham. Free to attend!

We have a fully-funded PhD studentship available to elucidate the host-adaptive traits of the human gut microbiome: bbsrcdtp.lifesci.cam.ac.uk/how-apply (targeted project: TRG-VET-AA26). Feel free to reach out with a CV and cover letter stating your interest in this project.

Applications to our free course on "Introduction to Experimental Design and Core Statistics" closes this Friday. Part of the @ukgibanetwork.bsky.social, this is a great opportunity to improve your statistical skills and get to meet other network members. Apply here: forms.office.com/e/sdys5HATUH

Applications to the first training event: "Introduction to Experimental Design and Core Statistics" of the UK GIBA Network+ (@ukgibanetwork.bsky.social) are now open! Taking place Dec 8-10 in Cambridge. Further info: www.giba-uk.org/training-opp... Apply here: forms.office.com/Pages/Respon...

📊 Want to boost your research skills? Join our 3-day training on Experimental Design and Core Statistics in Cambridge (Dec 8–10). ✅ Free to attend 🙋‍♀️ Open to all career stages 🚆 Travel and accommodation costs reimbursed Apply by October 17th 👉 www.giba-uk.org/training-opp...

Our working groups support the development of effective collaborations across the UK to advance research. Introduced by Franziska Denk (@denklab.bsky.social) at our #GIBANetworklaunch. Want to know our first 5️⃣ topics? Find out here 👇 www.giba-uk.org/working-groups

✔️ Flexible funds ✔️ Fellowships ✔️ Mobility awards Our director Jonathan Swann shares some of the ways we will expand the mechanistic understanding of the gut-immune-brain axis. More details will appear on our Network website in the coming days 👇 www.giba-uk.org/funding-oppo... #GIBANetworklaunch

“One of the key pillars of our network is training,” says @alexmsalmeida.bsky.social. We are committed to equip our members with the skills, tools and methods essential for research. Our first course was announced at our #GIBANetworklaunch 🌟 Want to know more? 👇 🔗 giba-uk.org/training-opp...

Representing the bioinformatics crowd at the #GIBANetworklaunch

The past two decades have seen a global explosion of research into the gut-immune-brain axis. There is great energy in #Southampton today for our #GIBANetworklaunch. Together, we are building a vibrant and diverse research community to fully realise GIBA's potential. Learn more 👉 www.giba-uk.org

🚨 New pre-print from the lab! We performed a large-scale meta-analysis of the uncultured gut #microbiome in >10,000 metagenomes enabling us to identify a new candidate biomarker of health. www.biorxiv.org/content/10.1...

The GIBA network will be launching on September 22nd with an in-person event in Southampton. Do come along to hear and share your thoughts on our plans to drive innovation in the gut-immune-brain axis field in the UK. Sign-up here: www.eventbrite.com/e/uk-giba-ne...

A new UK research network supported by UKRI will investigate how gut health impacts the brain, immune system, and mental wellbeing. Dr Alexandre Almeida (@alexmsalmeida.bsky.social) is part of the interdisciplinary team leading this new initiative. Read more: www.bio.cam.ac.uk/news/cambrid...

We're delighted that researchers from the @camvetschool.bsky.social are contributing to this important new network, advancing understanding of the gut-immune-brain connection.🧠👇🏽

Excited to be part of the leadership team of a new @ukri.org BBSRC Gut-Immunology-Brain Axis (GIBA) Network+ to drive further mechanistic understanding of the GIBA. See more: www.bio.cam.ac.uk/news/cambrid.... @camvetschool.bsky.social @cambridgebiosci.bsky.social

argNorm is published now academic.oup.com/bioinformati...

Me and a few of my mates got together and wrote a review on the current state of clinical translation of microbiome research. A great summary of the state of the art for microbiome research. www.nature.com/articles/s41...

Everyone thinking of using MR for microbiome studies should read this! So many microbiome MR work is published w/o any validation😠 Here, Kaitlin Wade et al. explain (very well!) that a good MR result can be inconclusive after appropriate subsequent sensitivity checks 🔗 www.nature.com/articles/s41...

Do you (like me) create a bunch of conda environments, then later forget what they're for, when they were last updated, or which tools are in them? If so, you might this little project: github.com/rrwick/conda...

New to bluesky - would appreciate a "retweet" please, so I can find everyone from twitter.

An in-depth analysis of 12,000 metagenomes looks at Enterobacteriaceae interactions in healthy humans These findings from @alexmsalmeida.bsky.social et al. highlight the critical role of the intestinal milieu in the colonization success of opportunistic pathogens

Use the Human Microbiome Compendium data! We made the data and code available, & created a website and R package to navigate the compendium. Links: - Website: microbiomap.org - Data: zenodo.org/records/1373... - R package: blekhmanlab.github.io/MicroBioMap/ - Code: github.com/blekhmanlab/...

Our paper out @CellCellPress: Structure guided discovery of viral proteins that inhibit host immunity Congrats Erez Yirmiya, Azita Leavitt, Gil Amitai, our collaborators at the Kranzusch lab, and coauthors A 🧵 1/10 www.cell.com/cell/abstrac...

New #MicrobiomeDigest is OUT microbiomedigest.com/2025/01/16/j... • Enterobacteriaceae in the human gut / @alexmsalmeida.bsky.social • microGalaxy / @bebatut.bsky.social • bacterial vaginosis /‬ @mikeusyk.bsky.social • invitation for the next week @microbiomevif.bsky.social & more. Happy 2025!

🆕 Blog! Our experts Prof @mjpallen.bsky.social Dr Falk Hildebrand @bioinf.bsky.social and Dr Aimee Parker explain that there is no evidence for a brain microbiome 🧠 https://buff.ly/40gVxNH

A paper in Nature Microbiology underscores the critical role of the intestinal environment in the colonization success of gut-associated opportunistic pathogens with implications for developing non-antibiotic therapeutic strategies. https://go.nature.com/4hgvQDA 🧪

🎉Huge congrats to @alexmsalmeida.bsky.social ‘s team on this fantastic publication! Honoured to have made a (tiny) contribution to our *first* work as collaborators. Here’s to many more 🥂🚀 @camvetschool.bsky.social @naturemicrobiol.bsky.social

OUT NOW - Ecological dynamics of Enterobacteriaceae in the human gut microbiome across global populations www.nature.com/articles/s41...

Interested in the ecological dynamics of Enterobacteriaceae across populations? Check out our new study 🧬

Very interesting study! Must read for everybody working on enterobacterales!

Well done @alexmsalmeida.bsky.social and team on this next work on Enterobacteriaceae colonisation!

Delighted to share the first peer-reviewed paper from our team @camvetschool.bsky.social where we investigate the ecological dynamics of Enterobacteriaceae in the human gut #microbiome: www.nature.com/articles/s41... @naturemicrobiol.bsky.social

Great to get this out before the holidays: Integration of metagenome-assembled genomes with clinical isolates reveals genomic signatures of Klebsiella pneumoniae in carriage and disease (www.biorxiv.org/content/10.1...)

We are thrilled to see 3 projects in the School receive funding from this call – congratulations to Alex Almeida (@alexmsalmeida.bsky.social), Charles Emogor, Máiréad Healy, and Zoe Kourtzi!

Really grateful to @acceleratescience.bsky.social for funding our project on combining AI and metagenomics to improve pathogen tracking. Look forward to getting started on this next year!

International consensus statement on microbiome testing in clinical practice - just out in Lancet Gastro & Hepat www.sciencedirect.com/science/arti...

I thought we learnt an important lesson during the pandemic - preprints should be taken with a grain of salt. I thought we did. www.theguardian.com/lifeandstyle...

I just made a first release of TNA - new tool to compare 2 bacterial genomes. Is shamelessly inspired by ACT, but should be simpler to use. Drag-n-drop two genomes: it runs BLAST for you and then you can visualize. For Mac, Windows 11, Linux tna.readthedocs.io

Today we publish an (in my opinion) important paper in @naturemicrobiol.bsky.social 🍾 showing that gut physiology and environment are factors explaining substantial variations in human gut #microbiome composition and #metabolism🦠 Fantastic work Procházková et al. 👏 www.nature.com/articles/s41...

I often get asked what is the best place to start to learn more about the human microbiome for those new to the field. I always default to this excellent collection that was put together by @npariente.bsky.social and Ashley York: www.nature.com/immersive/d4.... Any other good recommendations?