Excellent, concise summary of the threats of recent OMB proposal and suggested action items. DEADLINE TO SUBMIT PUBLIC COMMENTS IS JULY 13, 2026 AT 11:59 PM EASTERN TIME elizabethginexi.substack.com/p/what-we-ne...

Dandy #bloomscrolling

Elvis’s audiences were indeed, on average, slimmer.

Only 102 public comments so far on the biggest threat to publicly funded science in my lifetime. Please comment if you can. I know this sounds like "vote harder" but we have to keep fighting www.regulations.gov/document/OMB...

Politicization of science is a pathway to mediocrity, decline, and real-world failure. The White House and OMB might want more power to undermine America's once-leading R&D ecosystem, but doing so comes with costs: to careers, discovery, the economy, our health, and national security.

Just some flowers. Nothing to crow about.

“The drug that kept me alive for my children was built on a foundation of public investment. Taxpayers funded the research and the clinical trials. This country made a long bet on science, and I’m alive because it paid off.” www.ms.now/opinion/canc...

But is it running for governor?

'We primarily do comparative analysis using human stem cells/organoids and genetically modified mouse models, with some minor use of frog models. We use this approach because, for developmental anomalies, it is impossible to assess true function without in vivo models' @karenjliu.bsky.social

You don’t have to fit in to be beautiful. #bloomscrolling

Do it anyway.

People who request, then reschedule, then cancel meetings may not be literally the worst, but they are on the list.

Because I study 🧠, these points are important to me and may help you in your comments. NAMs have not yet supported an FDA approval for a CNS drug independent of animal data. Essentially every CNS therapeutic in clinical use came through animal model preclinical development. /2

🚨🧪🧵URGENT INPUT NEEDED: NIH asks input for next strategic plan-including emphasis on non-animal models (NAMs) to replace animals. Per NIH insider, anti-animal responses now outnumber scientists 200-700x. Please please provide input. Deadline: May 26, 11:59 PM ET. grants.nih.gov/news-events/...

Make. This. Movie.

“We couldn’t do so much if we had to do it right.”

If hitting is contagious, these guys could not catch a cold in a kindergarten. #baseball

Pick a Bond from photos you already have in your phone

*Note: I embellished for literary reasons. My review wasn't cranky at all! The manuscript was excellent and my motto in reviewing is #BuildDontBurn

We are again thankful for support on these projects from the National Institutes of Health. This is the crown jewel of public science in the world and we thank the public for supporting it and advocating for it /25

I try not to hate, but I hate Concur.

Enjoy moments of beauty whenever they arise.

Canada Geese on Lake Washington Beneath Mount Rainier

SLD;DR = showed left-handed DNA; didn’t read.

This set of reviewers are obviously all smart, attractive, and pleasant-smelling people whose parents loved them.

Please share widely. The new (simpler) MIRA R35 for Early Stage Investigators (ESI) NOFO is published. First due date is 10/2/2026. files.simpler.grants.gov/opportunitie...

Nice piece that includes my colleague Kevan’s pioneering research. Yet another reason to fund more science, not less! How an ‘Impossible’ Idea Led to a Pancreatic Cancer Breakthrough www.nytimes.com/2026/05/12/h...

First PROTAC gains FDA approval, bolstering targeted protein degradation and induced proximity ambitions www.nature.com/articles/d41...

I am “for your age” years old now, apparently.

New results published in the New England Journal of Medicine finds Moderna’s mRNA flu vaccine gave more protection against illness than the standard flu shot in a Phase 3 clinical trial.

Reviewer 2, are you okay?

Weather app, we need a little chat about what “0%chance” means.

Herman J. Muller

Slightly diminish a book: Breakfast of Runners-up

Slightly diminish a book On the Origin of Subspecies.

There needs to be a giant billboard in every major American city that touts this. In any other era except this suicidal science administration, this would be a miraculous, wondrous thing.

Weaken a film title: It’s a Good-enough Life

Happy birthday to #neurologist Santiago Ramón y Cajal (1852 - 1934), here in front of Purkinje and granule cells from a pigeon, based on one of his own drawings! 🧪🐡 #histsci Cajal &Golgi won the Nobel in 1906, “in recognition of their work on the structure of the nervous system”. He was as much of 🧵

Just makin' it clear for your asses. Erasing the voices of black and brown people is not "agree to disagree" territory.

Stillness in stone and water. While I was at Puget Sound this week, this rock caught my eye. So I created a 30-second exposure, which turned the water around it soft and smooth. I like how the long exposure reduces the scene down to shape, texture, and stillness. #PNWPhotography #SonyAlpha

Centralization of administrative processes and services across large, multiple departmental organizations drastically improves efficiency said no one that relies on those services ever.

“But let your ‘Yes’ be ‘Yes,’ and your ‘No,’ ‘No.’ Then login with 2FA and ecertify under penalty of perjury for the following time periods,”

Bougainvillea

I would like a word with whoever decided that all-text slides with dark gray text on a light gray background was a great choice for this mandatory training.

Clouds clearing

In related news, the dog has a 600% approval rating.

Less pomposities, more poppies.