Almost no one knows.

Sleep disturbances in Long COVID are underdiscussed. “Sleep disturbance may contribute to chronic inflammation in Long COVID by compromising certain inflammatory resolution pathways.” pubmed.ncbi.nlm.nih.gov/41650882/

Wonder what kind of weapons systems the Artemis II rocket has on it 🚀

Thrilled we have this new Comment out in @thelancetinfdis.bsky.social, arguing that to give Long COVID scientists more incentive to incorporate patient expertise throughout the research process, LC papers should all be subject to pre-publication review by patients. Free to read w/registration!

Wow, this is an incredible contribution.

*Very* helpful thread on PEM and PESE in ME/CFS.

it’s time for a His-odotus

The layers of harm the biopsychosocial model has done to patients, medicine, families & society is profound Excellent clip 👇

Training is badly needed. Please consider signing; it’s very easy.

A super-quick action open to people with ME/CFS or supporters in the U.S.—you just add your name to this call for improved medical education on ME/CFS! That’s it! (If you want to do more, sharing also helps!)

"Immune Cell Tied to Long COVID Fatigue Found" 'Their large-scale data analysis pointed to a distinct molecular state in a type of white blood cell known as CD14+ monocytes, which play a key role in immune defense.' www.miragenews.com/immune-cell-...

Oh hey it’s me, one of the nine million! With no approved treatment 🫠 If you have a few mins to send a prescripted email (and maybe even follow that up with a call? 😃) to help us ask Congress to finally fund ME/CFS research, I’d be so grateful. solvecfs.quorum.us/campaign/157...

Hoodoos in a rotting tree stump. Who needs travel when I have an Utah in the backyard?

Last post to highlight this survey. If you have #ME/CFS or #Longcovid and have tried hyperbaric oxygen please complete this survey. All experiences important. You can stop and complete at a different time allowing you to pace. Thanks @physiosforme.bsky.social www.physiosforme.com/post/new-sur...

The guide gleaned from many years of treating IACCs offers clinicians guidance on treating the conditions and diseases. Below is the guide, shared last year: www.coresinai.org/manual

Yes. So badly needed.

Platonism: A Very Short Reminder

New data from Stats Canada shows the % of adults reporting very good to perfect functional health declined across all provinces from 65.4% in 2019 to 56.4% in 2024 - driven by worsening emotional health & pain, with young people hit hardest 👀

Why do bad things happen to people with good CVs?

Catalog of Ships = Opening Credits

Individuality Suspended on some lofty branch, the moss dives for the bog. (Sometimes I piddle around with little lines like this and post them).

On this #LongCovidAwarenessDay, take a moment to watch Darren’s video. His story is very much like mine and many others. I too have lost the ability to work and become mostly housebound. It’s hardest thinking about how much I can no longer do with the kids. Research is slow; everyone’s moved on.

RFK Jr and HHS have launched a new website dedicated to Long COVID. Please remain skeptical: They will offer more junk science than real solutions, and use this as another opportunity to spread misinformation about vaccines.

Today @thesicktimes.org: We're excited to help introduce the new PLRC-RTHM Long COVID Treatment Guide, with an op-ed by @leticiasaurus.bsky.social and @jencurtinmd.bsky.social! thesicktimes.org/2026/03/12/a...

We're thrilled to release the #LongCovid Treatment Guide! This is a collaboration with @rthm.bsky.social to help patients & providers explore treatment options together. The guide focuses on 24 medications, but includes a few other interventions for breadth /1

ME/CFS folks, if you have spoons for this, I think moderating online groups, esp state-level groups, is a crucial intervention. Last I was in the loop on this, many of MEAction’s state-level Facebook groups were closed for lack of moderators, and it has really hampered state-level advocacy IMO.

What on earth is everyone talking about?

Same

I am clicking that link and accepting all cookies

George Wallace in 1962: "I started off talking about schools and highways and prisons and taxes and I couldn't make them listen. Then I began talking about n**rs and they stomped the floor." Donald Trump in 2023⬇️

It’s giving middle passage

Ok I have an #NEISvoid hot take: I agree we have too many Long Covid observational studies BUT I think we need to push for investment in pathobiology research more than trials. Identifying disease mechanisms can produce treatment targets to direct trials, instead of throwing spaghetti at the wall.

Classicists: ancient Greek didn’t use the metaphor of “pressing” (as in θλίβω) for what we call “expression”? That’s a Latin invention (as in exprimo and derivatives)?

New fallacy just dropped: the False Herring. When you distract an opponent with a fish story. Or When you, an unfaithful herring, distract an opponent.

The scholarly article: Gosh, there’s a lot to say on this topic and I’m unfortunately not going to be able to get around to any of it

3) Low-Dose Sirolimus (Rapamycin) for Long COVID clinicaltrials.gov/study/NCT069... 4) NE3107 for Long COVID clinicaltrials.gov/study/NCT068... 5) Tafenoquine for Babesiosis with Severe Fatigue clinicaltrials.gov/study/NCT066...

1) Lumbrokinase for LC, ME/CFS, Post-Treatment Lyme Disease clinicaltrials.gov/study/NCT065... 2) Antivirals for Long COVID Trial will test if two repurposed HIV antivirals can reduce symptom burden in adult participants with Long Covid compared to placebo. clinicaltrials.gov/study/NCT065...

Over on threads someone just use ai;dr and we all need to adopt that right quick

I feel I’m watching one of the events of Super Bowl history

Sam is Darn Old

Not a single thing we were told about #COVID turned out to be correct. A long thread 🧵

Has this study made the rounds of Bluesky #ME/CFS and #LongCovid #pwLC #pwME? “… FC differences in ME/CFS and long COVID patients indicated reduced and dysregulated regional coordination that may serve as candidate biomarkers of symptomatology in long COVID and ME/CFS.”

And ya know the last shall be first

Nature Immunology: Long COVID involves activation of proinflammatory and immune exhaustion pathways #ThatCovidLife #CovidIsNotOver

“Reinfection was associated with more than double the risk of a long COVID diagnosis” in a large study of children and adolescents.

long covid often presents as mecfs or similarly, which patient surveys have indicated carries a poorer quality of life than literally every type of cancer. it’s decimated my quality of life since contracting it in late 2022. exposing children to that fate for your own comfort is unconscionable

A sermon is the giving of stage directions from the stage to the audience for the aestheticization of the audience’s lives in accordance with the official script. It is stage directions rendered as an art form in its own right, and presupposes the audience to be aspiring aesthetes.

Ancient people died a lot. Pls revise Ancient people often died. Pls revise Ancient people died every day sometimes. Pls revise Ancient people, who are all dead now, were both dead and alive in ancient times.

Ancient people died a lot. Pls revise Ancient people often died. Pls revise Ancient people died every day sometimes. Pls revise Ancient people, who are all dead now, were both dead and alive in ancient times.