Banoo Malik🇨🇦
@banoomalik.bsky.social
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📥 180
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Origin of meiosis
#meiosis4eva
| Visiting research scientist @UMD | Views mine
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Banoo Malik🇨🇦
Jacob (Yaqub) Hanna - يعقوب حنا
12 days ago
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Iñaki Ruiz-Trillo
12 days ago
If we find a novel organism branching between protists and animals, is it a
#protist
or an
#animal
? 🤔 We here suggest that if it has 3 cell types, a polarized outer layer, a feeding opening, and responsive behavior, then it is an animal!
link.springer.com/article/10.1...
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A smartphone analogy to explore the origin of animals - The EMBO Journal
How animals evolved from their unicellular ancestor is a fundamental biological question. The fact that all animals are monophyletic—sharing a single common ancestor—implies their origin from unicellu...
https://link.springer.com/article/10.1038/s44318-026-00692-5#Abs1
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BWJones
16 days ago
This is kinda bonkers. In addition, 20 amino acids were found on Ryugu, along with uracil and vitamin B3. These have been found in other instances, but since the samples from Ryugu were collected directly from the asteroid and delivered in sealed capsules, contamination on Earth could be ruled out.
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Julia Van Etten
18 days ago
I have a new review out in TiG titled, “The ecology of horizontal gene transfer”! I’ve been thinking about these ideas for years and this field is growing so fast it’s becoming impossible to review it. I hope this paper sparks discussion on different ways we can look at DNA transfer!
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The ecology of horizontal gene transfer
Horizontal gene transfer (HGT) generates genetic variation in populations across all domains of life; however, most studies focus on individual transf…
https://www.sciencedirect.com/science/article/abs/pii/S0168952526000375?fr=RR-1&ref=cra_js_challenge
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Brett Baker
19 days ago
Having a hard time keeping up with the fast-moving field of origin of eukaryotes/Asgards archaea? Our new perspective article can help, we review the status of research over the last decade and where it's going. The archaeal roots of eukaryotic life
www.pnas.org/doi/10.1073/...
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Christine Moissl-Eichinger
21 days ago
Methanobrevibacter smithii is consistently associated with colorectal cancer. This has been confirmed by various studies, across numerous cohorts, including this recent one by our Lab
@medunigraz.at
www.nature.com/articles/s41...
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Cross-domain metabolic interactions link Methanobrevibacter smithii to colorectal cancer microbial ecosystems - Nature Communications
Here, the authors identify widespread disease associations of gut archaea, particularly in colorectal cancer, with further experiments revealing Methanobrevibacter smithii cooperation with cancer-asso...
https://www.nature.com/articles/s41467-026-69711-7
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RIP Chandler Fulton:
www.brandeis.edu/provost/lett...
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Sad News: Chandler "Chan" Fulton
https://www.brandeis.edu/provost/letters/2025-2026/2026-03-04-sad-news-chandler-fulton.html
20 days ago
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Buzz Baum
20 days ago
Archaea hit prime time:
www.bbc.co.uk/programmes/m...
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BBC Radio 4 - In Our Time, Archaea
How a discovery in the 1970s changed the theory of the origin of complex life on earth.
https://www.bbc.co.uk/programmes/m002sg10
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Brett Baker
20 days ago
Asgard archaea on CBC radio.
ici.radio-canada.ca/ohdio/premie...
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Asgard : Potentiel chaînon manquant de la vie complexe | OHdio | Radio-Canada
Écoutez l’extrait de l’émission Les années lumière : Asgard : Potentiel chaînon manquant de la vie complexe
https://ici.radio-canada.ca/ohdio/premiere/emissions/les-annees-lumiere/segments/rattrapage/2317069/asgard-potentiel-chainon-manquant-vie-complexe
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Laurence CROMER
21 days ago
Our lab just published a JoVE video article covering Live Imaging Characterization of Centromere Movements During Male Meiotic Prophase in A.thaliana The article and video present the technique for acquiring and analyzing these movements.
hubs.ly/Q0425wz20
#meiosis
#JoVE
#ScientificCommunication
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Live Imaging Characterization of Centromere Movements During Male Meiotic Prophase in <em>Arabidopsis thaliana </em>
Meiosis is a cellular division, essential for sexual reproduction. During meiotic prophase, homologous chromosomes of maternal and paternal origin ...
https://hubs.ly/Q0425wz20
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John Burns
21 days ago
I look at these kinds of protists ALL THE TIME. I have never seen them in situ like this. One cell. Absolutely remarkable.
#protistsonsky
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James McInerney
21 days ago
I'm thankful to MBE for publishing this paper. I wan't sure anybody would. The handling editor (I now know was Jeff Townsend) was great, as were the 2 reviewers. It is not an outcome/product/discovery, it is my way of thinking about HGT & pangenomes 1/3
academic.oup.com/mbe/article/...
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Genomic perplexity and the evolution of context-dependent function
Abstract. The fundamental principle that selection acts on a gene's function often assumes implicitly that this function is fixed and intrinsic. However, e
https://academic.oup.com/mbe/article/43/3/msag041/8497498
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Nature
21 days ago
Nature research paper: Homologous recombination deficiency and hemizygosity drive resistance in breast cancer
go.nature.com/4bcvflf
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Homologous recombination deficiency and hemizygosity drive resistance in breast cancer - Nature
Germline and somatic interactions define actionable genomic patterns driving acquired therapy resistance in breast cancer.
https://go.nature.com/4bcvflf
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Astera Institute
21 days ago
ICYMI an essay competition specifically for active researchers: 1st prize $30K, 2nd $10K, 3rd $5K. Public submissions only:
astera.org/essay-compet...
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Essay Competition
https://astera.org/essay-competition/
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Alex Naka
6 months ago
My group at Science has been running a big campaign to engineer new channelrhodopsins. Excited to share the first results from it today: a suite of highly sensitive new opsins. We call them "WAChRs". Everyday indoor office lighting is enough to activate them pretty strongly.
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Mart Krupovic
29 days ago
With Eugene Koonin, we propose a concept of “the selfish ribosome”, under which evolution of life is viewed as a ribosomal takeover, where the ribosome evolved to consume most of the cell’s resources, while other cellular componentry ensures the propagation of the ribosome.
arxiv.org/abs/2602.23268
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Corey Holt
about 1 month ago
🤩 Woahhh! Sounds like a blast! Not to be missed!
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Jonathan Eisen
about 1 month ago
🦠👀 🦠👀 🦠👀 🦠👀 🦠👀 🦠👀 🦠👀 🦠👀 🦠👀 🦠👀 🦠👀 🦠👀 🦠👀 🦠👀 🦠👀 🦠👀 🦠👀 🦠👀 🦠👀 🦠👀 🦠👀 🦠👀 🦠👀 🦠👀
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Kathryn (Katy) Appler
about 1 month ago
Beyond thrilled to share that our study has been published! This project encompasses years of work, including my thesis research on Asgard archaea in the
@archaeal.bsky.social
lab at
@utmsi.bsky.social
and
@texasscience.bsky.social
!!!
#MicroSky
#ArchaeaSky
1/12
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FEMS
about 1 month ago
💡 We are inviting you to nominate a woman in microbiology whose work or impact deserves to be seen. Selected nominations will be featured on the FEMS website and across our social media channels on International Women’s Day, 8 March. 👉 Who inspires you? Nominate them by 4 March .
buff.ly/AKyMbQD
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Brett Baker
about 1 month ago
New paper from my team detailing a greatly expanded genomic database of Asgard archaea revealing of high energy metabolism those related to eukaryotes! Led by
@katyappler.bsky.social
lots of help from
@jameslingford.bsky.social
@valdeanda.bsky.social
@kassipan.bsky.social
doi.org/10.1038/s415...
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Carl Zimmer
about 1 month ago
One of the biggest questions in biology is how complex cells evolved about 2 billion years ago. Here's my new story on how scientists are solving the mystery of eukaryotes like us. Gift link:
nyti.ms/4qMbo22
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https://nyti.ms/4qMbo22
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Andrew Roger
about 1 month ago
The 'devil is in the details'. You have to look beyond author claims and try to understand why the various studies have come to different conclusions and read the explanations given by the authors themselves.
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Thijs J. G. Ettema 🦠🔬🇳🇱🇸🇪🇪🇺
about 1 month ago
Our latest preprint: Together with the team of Jan Löwe,
@danieltamarit.bsky.social
and many others we discovered and characterized several Asgard tubulin genes and propose that microtubule architecture and dynamics evolved in Asgard archaea prior to eukaryogenesis
www.biorxiv.org/content/10.6...
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Max Raas
about 2 months ago
Recently, a Hypothesis was posed in
@jcellsci.bsky.social
in which the root of eukaryotes was placed between kinetoplastids and all other eukaryotes. From this, it was implied that LECA did not have a kinetochore. We argue this is highly unlikely. A 🧵(1/12) Read our reply here:
tinyurl.com/n87myhpr
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The LECA had a conventional kinetochore and the kinetoplastid kinetochore is a derived feature – a critical evaluation of Akiyoshi, 2025
Summary:Akiyoshi, 2025 presented a hypothesis with implications for the early evolution of eukaryotes and eukaryotic cell division machinery. In this Correspondence, the authors conclude that this hyp...
https://tinyurl.com/n87myhpr
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bioRxiv Evolutionary Biology
about 2 months ago
Cryptic Sex in Leishmania Depends on SPO11 Paralogs
https://www.biorxiv.org/content/10.64898/2026.02.05.703715v1
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Corey Holt
about 2 months ago
Applications are now open for our EMBO Practical Course in Computational and Experimental Microbiomics! 🧫🔬🖥️
meetings.embo.org/event/26-mic...
Come learn a mix of computational and experimental microbiome techniques from 6-8th July in beautiful Bath, UK! Registration Deadline: 11 May 2026
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Computational and experimental microbiomics
The critical contribution of microbiota to animal, plant and environmental health is now widely accepted. Progress has been driven by two parallel approaches: in silico analyses of large -omics data …
https://meetings.embo.org/event/26-microbiomics
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Postdoc position on Asgard archaea in Thiago’s new lab for someone well trained in biochemistry, cloning, and protein purification:
international.au.dk/about/profil...
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Postdoc in Archaea Microbiology - Vacancy at Aarhus University
Vacancy at Department of Biology - Microbiology, Aarhus University
https://international.au.dk/about/profile/vacant-positions/job/postdoc-in-archaea-microbiology
about 2 months ago
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Heartbroken
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about 2 months ago
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Banoo Malik🇨🇦
Science Magazine
about 2 months ago
"If you’re a parent dreading the first experiment or conference abroad, my best advice is what I was told: The hardest part is often thinking about going."
#ScienceWorkingLife
https://scim.ag/4bzRGTb
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Ross Waller
about 2 months ago
Spatial Proteomics Workshop for Protists (see more in thread below) Registration Early Bird Monday 22nd June 2026. Regular Monday 10th August 2026. There will be a conference dinner on day 1. To register visit
protistology.org.uk/autumn-meeti...
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Journal of Cell Science
3 months ago
Isadonna Tengganu and Ke Hu develop transfection and ExM protocols for Chromera velia, enabling direct comparisons with its parasitic apicomplexan relative, Toxoplasma gondi.
journals.biologists.com/jcs/article/...
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Courtney Stairs
2 months ago
The day is finally here!! On behalf of all the co-organizers the Comparative Genomics of Unicellular Eukaryotes website is open.
comparativegenomics2026.com
Invited speakers will be added to the website in the coming weeks. Watch this (well, that^) space!
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CGUE 2026 – Comparative Genomics of Unicellular Eukaryotes 2026. San Feliu, Spain. 5-10 October
https://comparativegenomics2026.com/
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Maiato Lab
2 months ago
Mitosis has a timing system. If chromosomes attach properly, cells divide on schedule and keep proliferating. If attachment is slow or incomplete, the delay is recorded — and daughter cells stop dividing. We explore this link in our new preprint. 🔗
www.biorxiv.org/content/10.6...
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Martin Steinegger 🇺🇦
2 months ago
FoldMason is out now in
@science.org
. It generates accurate multiple structure alignments for thousands of protein structures in seconds. Great work by Cameron L. M. Gilchrist and
@milot.bsky.social
. 📄
www.science.org/doi/10.1126/...
🌐
search.foldseek.com/foldmason
💾
github.com/steineggerla...
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Multiple protein structure alignment at scale with FoldMason
Protein structure is conserved beyond sequence, making multiple structural alignment (MSTA) essential for analyzing distantly related proteins. Computational prediction methods have vastly extended ou...
https://www.science.org/eprint/4QQQFGCSQEGFJVGUESWN/full?activationRedirect=/doi/full/10.1126/science.ads6733
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Satoshi Kawato 川戸智
2 months ago
Visualizing pairwise genome comparisons? No need to run BLAST separately anymore! 🧬 #gbdraw has implemented
#LOSAT
, a WASM-powered Rust reimplementation of BLASTN/TBLASTX. ✅ No local installation ✅ No data transfer (Serverless) Try it here:
gbdraw.app
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Javier del Campo
2 months ago
Genetic modification in dinoflagellate algae: Some successes, many failures
www.sciencedirect.com/science/arti...
#protists
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André Marques
2 months ago
A new extreme of meiotic evolution: ✔️ 𝗻𝗼 crossovers ✔️ 𝗻𝗼 gene conversion ✔️ 𝗻𝗼𝗿𝗺𝗮𝗹 meiosis & fertility Sex mimics clonality without becoming asexual, in the holocentric multicellular eukaryote 𝘙𝘩𝘺𝘯𝘤𝘩𝘰𝘴𝘱𝘰𝘳𝘢 𝘵𝘦𝘯𝘶𝘪𝘴. more about it:
www.biorxiv.org/content/10.6...
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This is only those employed in government labs. How many PhDs lost from US universities?
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2 months ago
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Rep. Jamie Raskin
2 months ago
This Muslim American Heritage Month, we recognize the many contributions this diverse community has made in MoCo, Maryland and across America. Together, we commit to opposing Islamophobia and all forms of hate that divide us.
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Ilhan Omar
2 months ago
"ICE will leave Minnesota if you hand over your voter rolls" tells you everything you need to know. This was never about immigration or fraud. It was always about rigging elections.
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Dan Froomkin/Press Watch/Heads Up News
2 months ago
NYT video analysis confirms victim’s gun was removed before he was shot. So he was unarmed.
https://www.nytimes.com/2026/01/24/us/minneapolis-shooting-federal-agents-video.html
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Anne Applebaum
2 months ago
This witness to Alex Pretti's murder not only refutes the governmen't story, but says she is afraid to go home because federal agents might arrest her. This is what it feels like to live under state terror.
www.documentcloud.org/documents/26...
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TincherSealedWitnessDec012426.PDF
https://www.documentcloud.org/documents/26505743-tinchersealedwitnessdec012426pdf/
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Steffi (she/her)
2 months ago
My second PhD project is now out as a preprint! Our observations of the synaptonemal complex in wild-type Nematostella suggested an incredible degree of conservation. Then, our mutants told a story of dramatic functional divergence. We were bamboozled on a regular basis with this one! 🧪
#meiosis4eva
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https://www.biorxiv.org/content/10.64898/2026.01.18.699972v1
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Javier del Campo
2 months ago
Eukan: a fully automated nuclear genome annotation pipeline for less studied and divergent eukaryotes
academic.oup.com/nargab/artic...
#protists
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Thomas Leeper
2 months ago
National media should really be covering the fact thay every major school, museum, and arts institution in the Twin Cities, and hundreds of local businesses are closed tomorrow to protest federal occupation. Nothing like this at this scale has happened anywhere in America anytime in living memory.
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Aaron Rupar
2 months ago
Jack Smith: "My fear is that we have seen the rule of law function in our country for so long that many of us have come to take it for granted. The rule of law is not self-executing. It depends on our collective commitment to apply it."
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Andrew Curry
2 months ago
For the 1st time, archaeologists have direct proof of far-flung social networks during the last Ice Age. “In times of climate crisis, cooperation—not conflict—was a successful strategy,” says
@cnrs.fr
's
@solangerigaud.bsky.social
. “It’s good to recall that as a lesson from our past.” 🏺
@science.org
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Ice age Europeans imported tools from distant lands, perhaps as souvenirs
Mementos may have reinforced vast social networks during turbulent times
https://www.science.org/content/article/ice-age-europeans-imported-tools-distant-lands-perhaps-souvenirs
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Rajiv McCoy
2 months ago
Pregnancy loss is common in humans, and chromosomal abnormalities are the leading cause. Using genetic data from ~140,000 IVF embryos, we show that maternal variation in meiosis genes influences recombination and aneuploidy risk. First authors:
@saracarioscia.bsky.social
&
@aabiddanda.github.io
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Common variation in meiosis genes shapes human recombination and aneuploidy - Nature
Analysis of data from pre-implantation genetic testing sheds light on the genetic basis of meiotic-origin aneuploidy, the leading cause of human pregnancy loss, identifying common genetic variants ass...
https://www.nature.com/articles/s41586-025-09964-2
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Aaron Reichlin-Melnick
2 months ago
🚨HOLY CRAP. An ICE whistleblower just revealed a secret memo authorizing ICE officers to break into homes without a judicial warrant, which DHS's own legal training materials say is unconstitutional! ICE then hid the memo from the public, passing it along by word of mouth and private conversation.
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