Thrilled to share this preprint on Klebsiella pneumoniae plasmids in a One Health setting 🦠 Fantastic work by @twinkler.bsky.social! 🎉 @irenlohr.bsky.social @margaretlam.bsky.social

Check out our latest cool work by talented postdoc @ronimiah.bsky.social and team on a programmable, selection-free CRISPRi tool in S.aureus.

Feels surreal to say but: I'm hiring! If you are or know anyone interested in looking at the evolution of phage resistance using A. baumannii and natural transformation, then this might be for you www.jobbnorge.no/en/available...

Don't put all your eggs🥚 in the same basket🧺 𝙋𝙨𝙚𝙪𝙙𝙤𝙢𝙤𝙣𝙖𝙨 𝙖𝙚𝙧𝙪𝙜𝙞𝙣𝙤𝙨𝙖: epigenetic ON/OFF switching of 𝙜𝙡𝙥𝘿 gene → diverse subpopulations in the host Cells with high 𝙜𝙡𝙥𝘿 → increased toxin production and motility Low 𝙜𝙡𝙥𝘿 cells stay stealthy Balances attack and evasion www.pnas.org/doi/10.1073/...

Pleased to share our lab-optimized chapter in Methods in Molecular Biology: “Activity-Based Protein Profiling of Serine Hydrolases in Bacteria.” Thanks to @christianslentz.bsky.social . doi.org/10.1007/978-...

We are looking for a highly motivated postdoc to work on pathogen interactions. Please send in your application via jobs.uzh.ch/job-vacancie...

New tenure track assistant professor position in molecular microbiology in our department @dmf-unil.bsky.social @unil.bsky.social! We are casting a wide net for an experimental molecular microbiologist. Apply here: wwwfbm.unil.ch/releve/appli...

Our work identifying new covalent inhibitors of Staphylococcus aureus serine hydrolyses from fragment libraries is out! great work from @tulsiupadhyay.bsky.social and our many collaborators, including @christianslentz.bsky.social, @mfellnerlab.bsky.social. #chembio link.springer.com/article/10.1...

Job alert 🦠🧪: We are looking for a postdoc (and PhD candidate!) to join our team at UCLouvain/de Duve institute in Brussels, Belgium. You will work on our ERC Starting Grant project aimed at characterizing cell cycle regulation in S. pneumoniae. More information here: dewachterlab.com/join-us/.

Happy to see this one out in @commsbio.nature.com www.nature.com/articles/s42... Great collaboration with @sergitp.bsky.social

More great things happening at #ESCMIDGlobal: PhD candidate @nadiaaftab.bsky.social introducing the concept of differential cultivability of single S. aureus cells under specialized media conditions..

Having a great time at ESCMID Global and proud of postdoc @ronimiah.bsky.social presenting his work on a programmable, selection-free CRISPRi system in S. aureus.

Mystique is here! When I started my position at @cmdi.bsky.social there were no readily available phage against my A. baumannii focal strain. The solution? Finding my own phage ofc. Mystique is a broad host range Acinetobacter phage, and I'm thrilled to see this work out today #PhageSky 🧪🦠

Contrary to popular belief, what is important in science is as much its spirit as its product: it is as much the openmindedness, the primacy of criticism, the submission to the unforeseen, however upsetting, as the result, however new that may be. – Francois Jacob www.nature.com/articles/s41...

After a great first session on pathogenesis, the second Klebsiella Seminar Series @klebclub.bsky.social will discuss a variety of different topics. Join us for the lightning talks selected from submitted abstracts 🗓️ Thursday @9AM EDT (3pm Central European Summer Time) #microsky

Work of our lab @univie.ac.at in close collaboration with the Hauck Lab @uni-konstanz.de was published in @naturemicrobiol.bsky.social today. A compound highly selective in targeting Neisseria gonorrhoeae using a novel mode of action. @cemess.bsky.social medienportal.univie.ac.at/en/media/rec...

New publication alert! 🥳 Jorunn Pauline Cavanagh and colleagues investigated the clinical relevance of the new species Staphylococcus borealis Have a look 👇 journals.asm.org/doi/10.1128/...

Welcome to todays CANS seminar by Kimberly Kline, Univ. of Geneva, Switzerland and Markus Lakemeyer, University of Jena, Germany 'Pathogenesis of Enterococcal biofilm-associated infection' 14:15-15.00 ´Chemoproteomic profiling of microbial interactions´ 15.00-15.45 MH Aud 5

Are you interested in the milk microbiome and finding strategies to prevent infections? Apply for this PhD position with a highly competitive salary, Northern Lights included. www.jobbnorge.no/en/available...

New article out in ACS Infectious Diseases! Using activity-based probes by H. Overkleeft, former PhD candidate @jalal228.bsky.social identified an alpha-amylase family protein of S. aureus supporting virulence during Galleria infection! @monaj66.bsky.social pubs.acs.org/doi/10.1021/...

Excited to report our studies that identified a new serine protease secreted by the gut microbe Bacteroides fragilis that regulates pain and inflammation through PAR2 activation. #ChemBio. Check it out!https://www.biorxiv.org/content/10.1101/2025.01.15.633241v1

How do bacteria sense potential threats in their environment and initiate protective measures? Researchers led by @knutdrescher.bsky.social have discovered that fragments of the bacterial cell wall serve as an alarm signal indicating danger in the environment. @biozentrum.bsky.social

We derive iron-siderophore interaction networks among Pseudomonas strains from sequencing data. One key insight: natural strains form dense networks, whereas pathogens are loners. With @frimanscience.bsky.social @zhiyuanli.bsky.social & Nanjing colleagues www.science.org/doi/10.1126/...

Check out this bombshell publication by Michael Fischbach @mfgrp.bsky.social and coworkers @stanford-chemh.bsky.social @stanfordmedicine.bsky.social, imagine a cancer immune therapy/vaccine where treatment begins and ends with a painless topical skin treatment! 🤯 www.nature.com/articles/s41...

Preprint alert from the lab! Exciting new work led by @ronimiah.bsky.social Introducing a programmable, selection-free CRISPRi system in S. aureus. www.biorxiv.org/content/10.1...