Kim Walker
@drwalkermsbanta.bsky.social
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Associate Prof at UNC-Chapel Hill studying Klebsiella virulence.
Looks to be yet another excellent seminar series!
add a skeleton here at some point
16 days ago
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Kim Walker
Caity Holmes
about 1 month ago
Our latest collaboration with Karthik Hullahalli's team on bacterial barcoding is now out! We developed a way to measure dissemination dynamics that controls for independent colonization events. This more accurately assesses how bacteria spread between tissues.
journals.asm.org/doi/10.1128/...
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The latest in our quest to understand the role of HMV and hypercapsule in convergent Klebsiella is out! So thankful to this team for making this project really fun!
@stphnslsbry.bsky.social
@leslieannaerobe.bsky.social
@margaretlam.bsky.social
@katholt.bsky.social
journals.asm.org/doi/10.1128/...
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The acquisition of rmpADC can increase virulence of classical Klebsiella pneumoniae in the absence of other hypervirulence-associated genes | mBio
Klebsiella pneumoniae is a global pathogen, and gene exchange between hypervirulent (hvKp) and classical (cKp) strains is a rising threat. It is essential to understand how hvKp genes impact virulence phenotypes and identify the cKp strain backgrounds most amenable to enhanced virulence. Hypermucoviscosity (HMV) is a critical virulence factor in hypervirulent K. pneumoniae, conferred by the rmpADC locus. The rmp genes are encoded on mobile genetic elements and have been detected in convergent antibiotic-resistant K. pneumoniae strains of concern. In this study, we explored the impact of rmp acquisition in a broad set of classical clinical isolates. We observed that HMV appears necessary, but not sufficient, for increased virulence. Sequence type, capsule type, and HMV capacity could not predict which classical isolates gain an rmp-dependent colonization benefit. These insights increase our understanding of the distinctions between cKp and hvKp and further our ability to identify and treat new strains of concern.
https://journals.asm.org/doi/10.1128/mbio.03122-25
about 1 month ago
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Really excited to be part of this project!
#KlebClub
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2 months ago
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reposted by
Kim Walker
Juan David Valencia Bacca
6 months ago
currentprotocols.onlinelibrary.wiley.com/doi/10.1002/...
Our new article in Current Protocols is out: Microbiologists, immunologists, host-pathogen folks: this one’s for you 🧬🦠
#Klebsiella
#HostPathogen
#Microbiology
Huge thanks to my mentor
@azmicro.bsky.social
for the guidance and support!
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Murine Models of Klebsiella pneumoniae Gastrointestinal Infection
Klebsiella pneumoniae (Kpn) is a Gram-negative opportunistic pathogen and a leading cause of hospital-acquired infections. The gastrointestinal (GI) tract serves as a critical site for Kpn colonizati....
https://currentprotocols.onlinelibrary.wiley.com/doi/10.1002/cpz1.70187
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reposted by
Kim Walker
Kelly Wyres
7 months ago
So excited that this is now online. It's been a huge collaborative effort to estimate the prevalence of capsule and O antigens associated with
#klebsiella
neonatal sepsis in Africa and South Asia. The first step to prioritising antigens for a vaccine to protect 1000s of newborns.
#MicroSky
#AMR
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Very excited to see this in print form! It was quite a journey and I learned ton along the way!
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7 months ago
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One of my favorite meetings!
add a skeleton here at some point
7 months ago
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Out fighting for my job with many “colleagues” in Raleigh, NC. And thanks to
@shonmcbride.bsky.social
for the poster inspiration!
#StandUpForScience
11 months ago
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Very useful indeed
add a skeleton here at some point
12 months ago
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reposted by
Kim Walker
Caity Holmes
about 1 year ago
It's that time of year! Registration and abstract submission for the 6th Klebsiella Seminar Series is now open. Participation is free and abstracts are due by February 16th. See the link below for details, and reach out to the organizers with any questions:
forms.gle/gxbvaC6FjzuS...
#KlebClub
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Klebsiella Seminar Series 2025
This form can be used to register only or register+submit an abstract for the 2025 Klebsiella Seminar Series. By registering, you will receive a Zoom Webinar link for attendance prior to the event. Re...
https://forms.gle/gxbvaC6FjzuSPtjD9
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reposted by
Kim Walker
Matthew Lawrenz
about 1 year ago
Last call! Abstracts are due Dec. 8 for the 2025 Mid-Atlantic Microbial Pathogenesis Meeting (MAMPM), which will be held Feb. 2-4, 2025. Lot's of short talk opportunities for trainees. Join us at the wonderful Wintergreen Resort for two days of great science! Please repost!
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MAMPM
February 2-4, 2025 Wintergreen Resort, Virginia
https://www.mampm.org/
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reposted by
Kim Walker
Contamination Club
about 1 year ago
Some stunning contaminants found on old plates in the back of the cold room 😍🧫
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reposted by
Kim Walker
Klebsiella Club
about 1 year ago
Let's increase
#klebclub
chatter on 🔵🦋! Klebsiella aficionados add your handle below and we will build a starter pack. 🔁 to spread the word
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Do you love Klebsiella?! Check this out!
add a skeleton here at some point
about 1 year ago
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Do you ❤️ capsules? Come learn NEW & INTERESTING things about capsules at our
#ASMMicrobe2024
symposium! 4 talks to be selected from abstracts. Please spread the word! Abstracts are due soon!
www.abstractsonline.com/pp8/#!/20188...
about 2 years ago
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reposted by
Kim Walker
Olaya Rendueles
about 2 years ago
KlebClub registration is now open for the 5th annual Klebsiella Seminar Series! Follow the link below and register to attend (for free!) or submit an abstract. We are excited for another great line up of keynote speakers this year! Follow
@klebclub.bsky.social
!
sites.google.com/view/klebclu...
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KlebClub
Klebsiella Virtual Seminar Series
https://sites.google.com/view/klebclub/home
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