#specificity #GOML www.biorxiv.org/content/10.1...

🌟 Transforming #SpatialGenomics Research! Vizgen's #MERFISH technology makes groundbreaking discoveries in neuroscience, oncology, & more accessible to researchers worldwide. With 310+ publications (161 peer-reviewed), its global impact is undeniable. Explore: hubs.ly/Q034jjc80

Sign and share www.change.org/p/petition-t...

🔬 Expanding the Limits of Discovery with MERSCOPE Ultra™ 🔬 With an expansive 3 cm² imaging area, easily image normal & diseased tissues, multistage embryos, or serial tissue sections in a single run. Eliminate batch effects & experimental variation! 🔗 vizgen.com/merscope-ult...

Welcome Portrai Inc, our first Certified Service Provider in APAC! 🌏 Portrai pioneers large-scale spatial transcriptomics and now brings #MERSCOPE Ultra™ expertise to researchers—delivering high-resolution, high-throughput spatial insights at scale. 🔗 vizgen.com/certified-se...

🚨 Customer Spotlight: MERFISH 2.0! 💡 MERFISH 2.0 is revolutionizing #SpatialTranscriptomics, delivering exceptional data even from challenging #PDAC samples with suboptimal RNA quality. Marco Genua from Fondazione Telethon shares his success! 👉 Learn more: info.vizgen.com/merfish2.0

ICYMI, our first preprint of 2025 is out, showcasing our first exploration of #SpatialTranscriptomics in plants using @vizgen.bsky.social #MERSCOPE. A great collab with @katielong.bsky.social and @cristobaluauy.bsky.social at JIC, and Ashleigh Lister and the #SingleCell team at Earlham Institute.

1/10 We are thrilled to share our preprint on spatial transcriptomics in wheat spikes led by the amazing @katielong.bsky.social and Ashleigh Lister. We resolved expression of 200 genes to cellular resolution. Pre-print👉 tinyurl.com/c7t3kncf., @johninnescentre.bsky.social @earlhaminst.bsky.social

The instruments at the SCOPE @umasschan.bsky.social are happy to welcome a new piece of equipment. The SCOPE staff is also quite excited about the new #MerscopeUltra. Contact us for more information if Merfish will help expand your research program. @vizgen.bsky.social #micrscopy #newtoys #dearsanta

Molecular Cartography of the Human and MouseDown Syndrome Brain www.researchsquare.com/article/rs-5...

Molecular Cartography of the Human and MouseDown Syndrome Brain www.researchsquare.com/article/rs-5...

Spatial Transcriptomics Reveals Expression Gradients in Developing Wheat Inflorescences at Cellular Resolution www.biorxiv.org/content/10.1...

We're excited to start 2025 with this preprint from a great collaboration between the Earlham Institute's #singlecell team and the Uauy Group at the @johninnescentre.bsky.social. 👏 #Spatial #Genomics

Mature cDC1 establish and maintain functional tertiary lymphoid structures within tumor lesions doi.org/10.1101/2024... @miriammerad.bsky.social

www.biorxiv.org/content/10.1... Dendritic cells type 1 control the formation, maintenance, and function of tertiary lymphoid structures in cancer

www.biorxiv.org/content/10.1... Dendritic cells type 1 control the formation, maintenance, and function of tertiary lymphoid structures in cancer

Merry Christmas! Be of good cheer - it looks like Iceland is going to join the EU. 🇮🇸 🇪🇺 🎄

Nature Spatial transcriptomic clocks reveal cell proximity effects in brain ageing www.nature.com/articles/s41...

𝗦𝗽𝗮𝘁𝗶𝗮𝗹 𝗧𝗿𝗮𝗻𝘀𝗰𝗿𝗶𝗽𝘁𝗼𝗺𝗶𝗰𝘀 𝗥𝗲𝘃𝗲𝗮𝗹𝘀 𝗘𝘅𝗽𝗿𝗲𝘀𝘀𝗶𝗼𝗻 𝗚𝗿𝗮𝗱𝗶𝗲𝗻𝘁𝘀 𝗶𝗻 𝗗𝗲𝘃𝗲𝗹𝗼𝗽𝗶𝗻𝗴 𝗪𝗵𝗲𝗮𝘁 𝗜𝗻𝗳𝗹𝗼𝗿𝗲𝘀𝗰𝗲𝗻𝗰𝗲𝘀 𝗮𝘁 𝗖𝗲𝗹𝗹𝘂𝗹𝗮𝗿 𝗥𝗲𝘀𝗼𝗹𝘂𝘁𝗶𝗼𝗻 www.biorxiv.org/content/10.1...

𝗦𝗽𝗮𝘁𝗶𝗮𝗹 𝗧𝗿𝗮𝗻𝘀𝗰𝗿𝗶𝗽𝘁𝗼𝗺𝗶𝗰𝘀 𝗥𝗲𝘃𝗲𝗮𝗹𝘀 𝗘𝘅𝗽𝗿𝗲𝘀𝘀𝗶𝗼𝗻 𝗚𝗿𝗮𝗱𝗶𝗲𝗻𝘁𝘀 𝗶𝗻 𝗗𝗲𝘃𝗲𝗹𝗼𝗽𝗶𝗻𝗴 𝗪𝗵𝗲𝗮𝘁 𝗜𝗻𝗳𝗹𝗼𝗿𝗲𝘀𝗰𝗲𝗻𝗰𝗲𝘀 𝗮𝘁 𝗖𝗲𝗹𝗹𝘂𝗹𝗮𝗿 𝗥𝗲𝘀𝗼𝗹𝘂𝘁𝗶𝗼𝗻 www.biorxiv.org/content/10.1...

Mindblowing paper creating spatial aging clocks 🤯🤯 ! Very neat use of spatial tx. Congrats to @brunetlab.bsky.social and all the authors

Republicans Cut Child Cancer Research From Funding Bill After Musk’s Meddling www.rollingstone.com/politics/pol...

🎆4 years in the making! Thrilled to share the 1st spatial single cell aging clock ⏰ www.nature.com/articles/s41... We use #AI + spatial transcriptomics to discover what makes some cells age faster/slower in the brain 🧠 Led by Eric Sun and awesome collaboration w/ @brunetlab.bsky.social🧵

BEAutiful study! Looking forward to perusing through this data. So thankful that it’s #openaccess I can’t be the only one excited, can I?

Benchmarking 6 Imaging-based #SpatialTranscriptomics methods #MolecularCartography #Xenium #MERSCOPE #MERFISH #EELFISH #STARmapPLUS 🐭🧠 Mutually exclusive co-expression rate/MECR Who wins👑? #CosMx Not even in short list😔 #bioRxiv 2024 www.biorxiv.org/content/10.1...

#SpatialTranscriptomics Developing Human Heart 12-13 pcw scRNAseq #MERFISH 238 cell type markers Analyzing the Cellular Communities Layered organization of ventricular #Cardiomyocytes can be directed by #Semaphorin-PlexinA intercellular signals🤠 #Nature 2024 www.nature.com/articles/s41...

Molecular and Spatial Signatures of Mouse Embryonic Endothelial Cells at Single-Cell Resolution e9.5/12.5/15.5 #ArterioVenousHierarchy & #Organotypicity of Embryonic #EndothelialCell scRNAseq #MERFISH #SpatialTranscriptomics #SciArt William Pu lab #CircRes 2024 www.ahajournals.org/doi/10.1161/...

Visit our website for more information about doing a merfish project and to discuss your project with SCOPE Staff @vizgen.bsky.social

Spatial transcriptomic clocks reveal cell proximity effects in brain ageing Huge work from the @brunetlab.bsky.social www.nature.com/articles/s41...

Thrilled to see this paper out!! 🧪 Spatial transcriptomics of brain aging and 'spatial aging clocks' identify cells that have pro-aging or pro-rejuvenating effects on their neighbors! Huge CONGRATS to Eric Sun and all authors! Fantastic collaboration with @jameszou.bsky.social! rdcu.be/d33uQ 🧵

Spatial transcriptomic clocks reveal cell proximity effects in brain ageing 🧠 🕙 Incredible study 🧪 in Nature from @brunetlab.bsky.social and the Zou lab 🎉 So many intriguing findings - including that T cells have a pro-ageing proximity effect on neighbouring cells 🤯 @natureportfolio.bsky.social

💬 "We're excited to push the applications of this technology and collaborate with others to drive innovation and discovery." We've become one of five global Certified Service Providers for the @vizgen.bsky.social MERSCOPE platform, and the only site in the UK. #SpatialGenomics #SingleCell

Remember Didier Raoult, the French microbiologist who set off the hydroxychloroquine craze? If you haven't been following, you might have missed that critics have pointed to ethical failings in hundreds of his papers – "ethical failings" meaning no or inadequate ethical approval.

It took four days from submission to publication, and nearly five years from publication to retraction. After campaigning by many, many scientists, and an investigation by Elsevier, an infamous paper on hydroxychloroquine as a COVID-19 treatment has been retracted. 🧪 www.science.org/content/arti...

"The brain microbiome: could understanding it help prevent dementia?" The answer to this question is yes. www.theguardian.com/lifeandstyle...

In a new technical blog, Senior Research Assistant Ashleigh Lister guides you through her workflow for employing @vizgen.bsky.social MERSCOPE technologies in #plant tissues, mapping out #gene activity in situ. www.earlham.ac.uk/articles/how... #SpatialTranscriptomics #PlantScience 🧪🌿

1. Integrated analysis of >250,000 single cells from 70 healthy spanning 13 niches 2. Spatial proteomics and transcriptomics (MERSCOPE) atlases comprised of >2 million cells 3. iIntroduce AstroSuite advanced AI-assisted bioinformatics toolkit www.biorxiv.org/content/10.1...

Nominating this paper for paper of the year ! Such a stunning work from Xiaowei lab. www.biorxiv.org/content/10.1...

📽️ Our recent webinar with @vizgen.bsky.social is now available to watch on demand. Earlham Institute scientists shared their journey of working with the MERSCOPE #SpatialTranscriptomics platform, offering insights on their methods for working with non-model samples. us02web.zoom.us/rec/componen...

Nominating this paper for paper of the year ! Such a stunning work from Xiaowei lab. www.biorxiv.org/content/10.1...