New in @nature.com, researchers combined single-nucleus RNA sequencing, high-resolution #spatialtranscriptomics, and proteomics to map the molecular architecture of mid-gestational prenatal Down syndrome cortex and a trisomic Ts65Dn mouse model. (1/3)

Just published in Cell Press: Researchers used MERSCOPE® to show how microglia and astrocytes coordinate synapse remodeling in the intact mouse brain, revealing a spatially orchestrated glial dialogue that fine-tunes neural circuits. hubs.ly/Q03SdHXN0

Join us at #SfN25 to explore how high-sensitivity #spatialtranscriptomics is reshaping brain research. Stop by booth 513 and our 2 poster sessions to see how MERFISH 2.0™ and MERSCOPE Ultra™ support deeper, more precise insights into the complexity of the brain.

Today at #SITC2025: Get a first look at how MERFISH 2.0™ data generated on MERSCOPE Ultra™ is combined with InSituPlex® multiplex immunofluorescence on sequential sections to decode the tumor–immune microenvironment. 12:15-1:45 p.m. & 5:35-7 p.m. #SpatialBiology #SpatialMultiOmics

Choosing a spatial platform isn’t just about the next run. It sets you up for your next few years. See the whole picture and pressure-test your options with our Buyer’s Checklist: hubs.ly/Q03QRXVC0

Reminder: Join us 10/30 for the Labroots webinar: From Myelin Damage to Immune Dysfunction: Unravelling the Aging Brain Updated times: 6 am PDT | 9 am EDT | 2 pm CET | 10 pm SGT Register: www.labroots.com/ms/webinar/m... #SpatialTranscriptomics #Neurobiology #SpatialBiology

Spatial biology in 3D. In Genetic Engineering and Biotechnology News, read how combining spatial transcriptomics & multiplex proteomics clarifies tumor–immune signaling & bridges mechanistic insight into clinical readouts. Vizgen’s Manisha Ray weighs in on what’s next for analysis: hubs.ly/Q03PPC210

Join us 10/30 for a Labroots webinar with Dr. Janos Groh: From Myelin Damage to Immune Dysfunction: Unravelling the Aging Brain. Hear how single-cell + spatial transcriptomics reveal glial–immune interactions driving neurodegeneration. Register: hubs.ly/Q03N0rVJ0

Vizgen’s new Cell Atlasing Grant Program is now open. Top 5 tissue types receive one free MERSCOPE Ultra™ slide run using MERFISH 2.0™. Choose custom 960-gene or 815-gene pre-designed panels (IO, Brain, Breast). Apply by 10/24. HCA members only. hubs.ly/Q03NCPPv0

MERFISH 2.0™ delivers a substantial increase in sensitivity, enabling detection of up to 10× more transcripts per field of view. Discover how MERFISH 2.0 is transforming spatial biology for researchers like Dr. Bourdenx: hubs.ly/Q03LCNrY0 #SpatialBiology

New data release highlights the power of MERSCOPE Ultra to capture high-resolution #spatialtranscriptomics across a 3.0 cm² imaging area: • Mouse embryo tissue (E10, E12, and E14) on same slide • Normal and Alzheimer’s human brain on same slide hubs.ly/Q03KH7VN0

Next-gen spatial transcriptomic tools are helping overcome the challenge of degraded & FFPE samples. Vizgen co-founder Jiang He explains how these advances are opening new doors for research in oncology, neuroscience & beyond: www.biocompare.com/Editorial-Ar...

Just published in Nature: U Mass Chan Medical School, a Vizgen Certified Service Provider, mapped the brain’s molecular landscape across the human lifespan using MERSCOPE®, single-cell RNA-seq & genomic data. Read: hubs.ly/Q03JsW0z0 #SpatialBiology #Neuroscience #AgingResearch

From discovery to clinical research, #SpatialBiology is shaping precision medicine. With Vizgen, researchers now access: ➡️MERFISH 2.0™ spatial transcriptomics ➡️InSituPlex® multiplex protein analysis ➡️STARVUE™ AI image analysis Explore our tech: hubs.ly/Q03GPSL70

How do disseminated tumor cells reveal themselves in the bone marrow? Using MERFISH 2.0™, Mark Watson, Ph.D.'s team can map 200K–500K cells from bone marrow aspirates and distinguish DTCs from other populations w/ a 140-gene panel. Full webinar: hubs.ly/Q03GgGLm0

New in @science.org: Researchers paired PEtracer with Vizgen’s MERSCOPE® to map how tumors evolve in vivo—showing how cell ancestry and local microenvironments shape growth and revealing new insights into tumor biology. 🔗 www.science.org/doi/10.1126/...

MERFISH 2.0™ enables in situ spatial transcriptomic imaging in fixed frozen mouse bone marrow. ✨ At SR-TIGET, researchers quantified millions of transcripts— unlocking new insights into how cells interact in health and disease. Explore MERFISH 2.0: vizgen.com/technology/#... #SpatialBiology

In @cp-cellreports.bsky.social: Researchers used MERSCOPE to help uncover how basophils activate fibroblasts to drive persistent skin inflammation, offering clues for potential new treatments for conditions like atopic dermatitis. www.cell.com/cell-reports...

Congrats to the winners of the 2025 Heidelberg MERFISH 2.0™ Grant Program! 🎉 In partnership with scOpenLab, we’re supporting cutting-edge spatial transcriptomics projects using MERFISH 2.0 and predesigned gene panels. We can’t wait to see how these projects progress!

Just launched: Vizgen’s Summer of Spatial Technology Evaluation Program! Test industry-leading spatial transcriptomics & proteomics workflows on your own samples with expert support & exclusive pricing. Limited to 10 projects—ends 9/22. Learn more: info.vizgen.com/form-summer-...

In Nature: Engineered macrophages eliminated liver metastases in mice by restoring CD8⁺ T-cell activity and reprogramming the tumor microenvironment. MERSCOPE® spatially mapped co-localized immune signals, revealing T-cell rejuvenation in the TME. www.nature.com/articles/s41... #Immunotherapy

What makes spatial transcriptomics different? • Single-cell resolution in spatial context • Preserves tissue structure • Reveals insights beyond traditional methods Explore the basics: vizgen.com/what-is-spat...

New in Cell: CXCL12 identified as a key genetic driver of coronary artery anatomy. GWAS + spatial transcriptomics using MERSCOPE reveal how gene expression shapes heart development: www.cell.com/cell/fulltex...

Now in Singapore: MERSCOPE Ultra™! We're thrilled to announce the first MERSCOPE Ultra install in Southeast Asia at LifeStrands Genomics, in partnership w/ Genomax Technologies. Explore MERFISH 2.0 services now available to researchers across the region: spatial.lifestrandsgx.com/vizgen-mersc...

Struggling with cell segmentation in complex tissues like multinucleated muscle or abnormally shaped cells? Enhance your cell segmentation with Vizgen's Cellpose2 Plugin! Learn more about VPT and the plugin: vizgen.com/vpt/ #SpatialBiology

More tissue. More speed. More power. MERSCOPE Ultra™ brings 3X imaging area, 1.8X faster run time, and MERFISH 2.0 chemistry, all with sub-cellular resolution and FFPE compatibility. See how spatial genomics scales: vizgen.com/merscope-ult... #SpatialGenomics

Uncovering how cells organize into functional niches is a major challenge in spatial biology. A new study in Nature Genetics combines deep learning w/spatial transcriptomics from MERSCOPE® to map tissue architecture and cell communication across millions of cells. www.nature.com/articles/s41...

New study featured on the June cover of Nature Neuroscience used Vizgen’s MERSCOPE® to uncover how microglia and CD8⁺ T cells drive white matter degeneration in aging brains. Learn more: vizgen.com/study-publis... #SpatialBiology

Ultivue by Vizgen’s new ADC OmniVUE™ Panels integrate advanced InSituPlex® assays with the STARVUE™ image data science pipeline, bringing speed, scale, and pathology-grade precision to clinical and translational research. Learn more: ultivue.com/products/omn...

🐟 MERFY Duo has landed in Singapore! Take part in Vizgen’s #Cellfie promotion at #HCA2025 for a chance to win a MERSCOPE Ultra slide run using MERFISH 2.0 at Vizgen Lab Services. Stop by booth #2 to learn more and explore the future of spatial biology with us.

🐟Meet the Vizgen mascots! From Merfy to Ollie and now Merfy Duo (hatched this spring with MERFISH 2.0), each marks a milestone in spatial transcriptomics. Heading to #HCA2025 in Singapore? Swim by our booth to meet the crew—and maybe reel in your own!

Learn how combining MERSCOPE Ultra™ and InSituPlex® provides a more comprehensive view of immune infiltration, tumor biology, and spatial organization within human FFPE cancer samples.  Download our #AACR25 Poster: hubs.ly/Q03qzRMG0

Vizgen is proud to be a silver sponsor for #HCA2025. ✨ Stop by booth #2 to meet the Vizgen team and explore our latest innovations in spatial multi-omics. #SpatialBiology #SingleCell

We’re headed to the 2025 WEHI Spatial Technology Symposium in Melbourne, June 5-6. Join us and Integrated Sciences as we highlight the latest in spatial biology, including MERFISH 2.0™ and MERSCOPE Ultra™. Register: www.eventbrite.com.au/e/wehi-spati... #SpatialBiology #SpatialMultiOmics

New pre-print: Researchers use MERSCOPE® to map spatial gene expression in human brain organoids modelling the midbrain and hindbrain. Read it here: www.biorxiv.org/content/10.1... #SpatialBiology

New in Nature Biotechnology: MERFISH 2.0™ and other advances in spatial transcriptomics are transforming our understanding of disease mechanisms. Read it here: www.nature.com/articles/s41... #SpatialTranscriptomics #SpatialBiology

Join us & Global Engage on 5/28 to explore how Vizgen’s new MERFISH 2.0™ chemistry and the MERSCOPE Ultra™ Platform are advancing spatial genomics—unlocking new possibilities for FFPE and archived tissue samples. Register here: global-engage.com/product/webi... #SpatialBiology #MERFISH

Heading to #OzSingleCell25 in Sydney 5/21-5/23? Don't miss our presentations and be sure to stop by Booth #5 to explore the latest in spatial biology, including MERFISH 2.0™ and MERSCOPE Ultra™. See you there! #SpatialBiology

We're headed to Int'l Spatial Biology 2025, May 15–16 in The Hague! Join Mickael Ploquin on 5/16 at 9:55 a.m. for: “Extending Spatial Transcriptomics to Challenging Tissues: Enabling Discovery with MERFISH 2.0.” Learn more: global-engage.com/product/spat... #SpatialBiology

Join us & Global Engage on 5/28 to explore how Vizgen’s new MERFISH 2.0™ chemistry and the MERSCOPE Ultra™ Platform are advancing spatial genomics—unlocking new possibilities for FFPE and archived tissue samples. Register here: global-engage.com/product/webi... #SpatialBiology #MERFISH

Join Vizgen and Integrated Sciences for the 2nd MERSCOPE® ANZ User Group Meeting, on 5/20 at The University of New South Wales. Food will be provided, but space is limited, so register early to secure your spot and book office hours: www.integratedsci.com.au/merscope-ugm...

Now launched! Vizgen’s new MERFISH 2.0™ delivers up to 10x improvements in transcript detection, expanding spatial biology to more challenging sample types like FFPE tissues. Early-access users share insights in @genomeweb.bsky.social: www.genomeweb.com/gene-express... #SpatialBiology #MERFISH

One hour from now at #AACR25! Two poster sessions exploring new advancements in spatial transcriptomics and proteomics. Also stop by booth #3219 for live demos, fun prizes, and to learn more about our latest launches including the new MERFISH 2.0™ and ADC OmniVUE™ panels. #SpatialBiology

We’re having a great time showcasing all of our multi-omics offerings at #AACR25! Stop by booth #3219 for live demos, fun prizes and to learn more about our latest advancements including the new commercial launch of MERFISH 2.0™ and ADC OmniVUE™ panels. #SpatialBiology

Today, Vizgen takes a major step forward in our mission to unlock deeper biological insights from foundational discovery to translational research with the global launch of MERFISH 2.0 and ADC OmniVUE™ panels. Learn more in today’s announcement: vizgen.com/vizgen-expan...

A new @cp-cellreports.bsky.social study leveraging MERFISH tech links RNA localization to cell migration, deepening our understanding of gene regulation. This research could help inform future studies in wound healing, cancer metastasis, and mechanobiology. Read here: www.cell.com/cell-reports...

In a new article from The Pathologist, Vizgen’s Gourab Chatterjee and Lorenz Rognoni share how spatial image data science is giving researchers and pathologists unprecedented insights into tissue structure and cellular interactions. Read here: thepathologist.com/issues/2025/...

A new pre-print study from researchers at Stanford utilized the MERSCOPE® Platform to reveal how aging alters the function, morphology, and mRNA distribution of microglia. Read the full pre-print: t.co/RmW36N6zni #SpatialBiology #MERSCOPE #MERFISH

Spatial Spotlight #7 March is #NationalKidneyMonth, so we’re spotlighting this #MERSCOPE data image of an FFPE human kidney cortex, showing glomeruli filtering units and epithelial cells (tubule). Transcripts from a 140-gene panel are displayed. 📷: Dr. Christoph Kuppe, RWTH

We welcome @scope-umasschan.bsky.social as a Vizgen Certified Service Provider! 🎉 As a long-time collaborator & early adopter of #MERFISH, SCOPE now provides full-service spatial genomics solutions to accelerate biomedical research using #MERSCOPE Ultra™. Learn more: vizgen.com/certified-se...