Fantastic work! CoppaFISH is an open source, cheap, 3D (🤯) spatial transcriptomics method that can be aligned to multiple modalities: in vivo 2P recordings (🤯🤯), immunostainings, and more! Congrats to all the authors and happy to have been able to contribute!

Making "AI Scientists" has become a hot topic lately. The first reference I could find was from 2008. The term has been used for 20 years! Like "Adam," an AI Scientist robot for studying yeast was published in 2009. I wrote a short post about the term and what it means now. diffuse.one/p/w1-001

Meet our new Future Leader Fellows!👏 Introducing @mbourdenx.bsky.social, Dr Sophie Morse & Dr Wioleta Zelek who have been awarded prestigious Future Leader Fellowships from @ukri.org ⬇️ Read more about their work👉 buff.ly/JOH2d9N

🤖 Could an AI scientist help unlock the secrets of dementia? Dr @mbourdenx.bsky.social (@ukdri.ac.uk at UCL), is working with @futurehousesf.bsky.social to explore how AI is transforming research. buff.ly/O8RjZIX #UCLDementia #WorldAlzheimersMonth

Huge congratulations to Dr @angelikaza.bsky.social and Dr @mbourdenx.bsky.social who have both been awarded @ukri.org Future Leaders Fellowships! 🙌 @uclqsion.bsky.social @ukdri.ac.uk Find out about their exciting projects: www.ucl.ac.uk/brain-scienc...

“Ultimately, I see AI leading to an acceleration in discovery in dementia research that could be transformative for patients" says Dr @mbourdenx.bsky.social @ukdri.ac.uk, who is working with an "AI scientist", a system that can analyse data and suggest new research directions not yet explored

I’m very happy 🥳 to share our new collaborative work, out today in Science Advances! Many thanks to all the co-authors! Differential pathological dynamics triggered by distinct Parkinson patient–derived α-synuclein extracts in nonhuman primates | Science Advances www.science.org/doi/10.1126/...

"The biggest mystery is not why arXiv succeeded. Rather, it’s how it wasn’t killed by vested interests intent on protecting traditional academic publishing." www.wired.com/story/inside...

Flabbergasting www.theatlantic.com/health/archi...

RNA xkcd.com/3056

Sur les retraites, Bayrou a menti. Le "déficit caché" des retraites n’a jamais existé. Pour justifier son refus d'abroger la réforme des retraites, il avait inventé un déficit de 55 milliards en 2030. La Cour des comptes dit que ce sera 5 fois moins. Maintenant : abrogation.

🚨Cool Job Alert 🚨consider joining this amazing and rocknroll lab

Tesla paid $0 in federal income tax last year. 2022: $0 2021: $0 2020: $0 2019: $0 2018: $0 Tesla reported $6.7 billion in profit in those years.

New in @naturecomms.bsky.social: I'm thrilled to share with you our latest work that applies #srRNAseq to understand splicing accuracy across human introns, tissues and in the context of ageing and neurodegeneration www.nature.com/articles/s41...

After spending 4 years in the USA for my postdoc and my daughter being born there, it always felt (and still feels like!) a second home. So it’s utterly sad to see what’s happening now. I stand with all my American friends! Resist ✊💪

Notre programme est prêt. Nous sommes au travail. Plutôt que des aventures personnelles, nous faisons des propositions concrètes pour dessiner un horizon souhaitable. www.leparisien.fr/elections/pr...

That’s completely crazy ! And worrisome …

Still waiting to see most UK and French universities to do the same …

After 4y in the making, I am super excited that my main PhD project is published 🎉🥳🎉🎉🥳 www.nature.com/articles/s41... LEMUR is a tool to analyze multi-condition single-cell data and model differential expression as a continuous function of the cell-state space. Some highlights⬇️

🔥 chatomics! I regret not learning this well in college—and it changed how I approach bioinformatics today. Here’s my story and why you should avoid my mistake. 🧬

Paper alert from the Duff Lab 🚨🚨 My amazing colleagues showed that, in novel MAPTKI models, hyperphosphorylation (in absence of aggregation or even seeding) is sufficient to drive synapse loss and cognitive deficits. Huge implications for preclinical research and the way to therapies. Have a read!!

Mindblowing paper creating spatial aging clocks 🤯🤯 ! Very neat use of spatial tx. Congrats to @brunetlab.bsky.social and all the authors

Help from the MRI community needed: I would like to plot simple regional expression of a protein in the Schaefer atlas. I have a vector of values per region for the atlas. I can’t seem to find my way around that simple thing. Any help will be appreciated!! @nilearn.bsky.social ?

It seems that a lot of people have transitioned from X to here, however I feel that institutes/centres/unis are still missing. Did you try to convince yours to move? If so, how?

New on BioRxiv: We report a new, endogenous molecular clock in unmodified human cells and tissues. It is ticking away right now in almost every cell in your body. Paper here: www.biorxiv.org/content/10.1... 1/

Aging starter pack! go.bsky.app/5UXXaDA

I will not hide my inner convictions anymore. Be the change you want to see in the world ! #AcademicSky 🧪

So happy to this story led by Steph Fowler (Duff lab at UCL, now leading her own lab at Oxford) finally out. Amazing to see tau filaments in situ! Now I want to know what is this additional density and what is the tether!

Sounds like a fascinating approach!

🧠Sharing this Starter Pack again as the list has now reached 80 people! A great mix of Profs/PIs/Post-docs/PhDs/Technicians. Please re-post so it can reach a wider audience as I'm sure there are more of us out there ☺️🦋 go.bsky.app/S6FfsTp

Delighted to share our work to develop a genomic DNN, Enformer Celltyping, to accurately predict epigenetic signals in previously unseen cell types has now been published doi.org/10.1038/s414...