Anubhav Prakash
@prakash-patterns.bsky.social
📤 24
📥 61
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Kind of experimental biologist interested in shapes and patterns.
pinned post!
We show the Organ of Corti is composed of adhesion-molecule based compartments and the interaction between these compartments (compartment coupling) drives pattern and polarity. This seems like a fundamental design principle of developing tissues.
add a skeleton here at some point
20 days ago
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link.growkudos.com/1efpeb7d8n4
A short article is now available at Kudos on our work
@earlab.bsky.social
at
@ncbsbangalore.bsky.social
about how the cochlea generates its pattern.
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Cochlea generates patterns by interacting with neighbours
We wanted to understand how cells arrange into precise patterns as the cochlea develops its spiral shape. We found that the cochlea is divided into smaller domains, each organising independently whil...
https://link.growkudos.com/1efpeb7d8n4
about 7 hours ago
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@earlab.bsky.social
add a skeleton here at some point
13 days ago
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reposted by
Anubhav Prakash
Sara Wickstrom
19 days ago
My lab
@mpi-muenster.bsky.social
is looking for a computational biologist with a passion for imaging and spatial biology. A staff scientist position with long-term perspective! Apply and spread the word 🙏
jobs.mpi-muenster.mpg.de/jobposting/0...
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Computational image analyst (m/f/d)
The Max Planck Institute for Molecular Biomedicine in Münster, Germany, has an opening for a
https://jobs.mpi-muenster.mpg.de/jobposting/0b62e338d834d8397afd8d521e2c7996841d1f680
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Editor's insightful commentary on our work in cochlear morphogenesis.
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19 days ago
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reposted by
Anubhav Prakash
EMBO Molecular Medicine
20 days ago
Our September issue is online!
www.embopress.org/toc/17574684...
On the cover: AAV-mediated delivery of Clic5 restores inner ear structure & function in a model of hereditary hearing and balance loss 👉
doi.org/10.1038/s443...
Scientific image: R. Hahn & K. Avraham, at Tel Aviv University
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EMBO Molecular Medicine: Vol 17, No 9
EMBO Press is an editorially independent publishing platform for the development of EMBO scientific publications.
https://www.embopress.org/toc/17574684/17/9
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We show the Organ of Corti is composed of adhesion-molecule based compartments and the interaction between these compartments (compartment coupling) drives pattern and polarity. This seems like a fundamental design principle of developing tissues.
add a skeleton here at some point
20 days ago
1
6
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reposted by
Anubhav Prakash
National Centre for Biological Sciences, Bengaluru
about 1 month ago
#LatestPublication
In a latest study published in PLOS Genetics, Ramankaushik and team from Dr Raj Ladher's lab describe a new role for protocadherin-15 in patterning the hair cell. 🎉Congratulations to the team!
journals.plos.org/plosgenetics...
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Role of Pcdh15 in the development of intrinsic polarity of inner ear hair cells
Author summary Hearing, like other sensory modalities, is essential for animals to perceive and interact with their environment. The cochlea, the auditory sensory organ, develops under tight genetic r...
https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1011825
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preprint: Using a combination of experiments and theory, we show that force patterning at apical junctions drives three-dimensional spatial organisation in multi-cell-type epithelia. Give us your comments!
add a skeleton here at some point
3 months ago
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reposted by
Anubhav Prakash
BioPatrika
4 months ago
#authorinterview
Anubhav Prakash
@prakash-patterns.bsky.social
from Prof Raj Ladher lab
@earlab.bsky.social
, NCBS
@ncbsbangalore.bsky.social
talks about his work on "Pushing and pulling cells from chaos to order"
biopatrika.com/academia/res...
@natcomms.nature.com
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Pushing and pulling cells from chaos to order - BioPatrika
Researcher Spotlight - Pulling cells: Using a combination of experiments and mathematical modelling, we show that the tuned differences in the mechanical properties of junctions can organise cells int...
https://biopatrika.com/academia/researcher-spotlight/pushing-and-pulling-cells-from-chaos-to-order/
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reposted by
Anubhav Prakash
National Centre for Biological Sciences, Bengaluru
5 months ago
#LatestPublication
in
@natcomms.nature.com
by Dr Raj Ladher & team show that fine-tuned junctional mechanics are vital for aligning polarity in chicken cochlea. 🎉Congratulations to the team!
@prakash-patterns.bsky.social
@earlab.bsky.social
Read here:
www.nature.com/articles/s41...
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Junctional force patterning drives both positional order and planar polarity in the auditory epithelia - Nature Communications
Sound is sensed in the cochlea through a precisely organised epithelium. Prakash and colleagues show cellular organisation results from differences in junction contractility, finding mechanics is suff...
https://www.nature.com/articles/s41467-025-58557-0#Sec6
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My PhD work on the development of spatial organisation and planar polarity in avian auditory epithelia is now published
@natcomms.nature.com
doi.org/10.1038/s414...
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Junctional force patterning drives both positional order and planar polarity in the auditory epithelia - Nature Communications
Sound is sensed in the cochlea through a precisely organised epithelium. Prakash and colleagues show cellular organisation results from differences in junction contractility, finding mechanics is suff...
https://doi.org/10.1038/s41467-025-58557-0
5 months ago
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