This image here shows a 3D-rendered cristae from the mouse's inner ear. In red ♥️ is F-actin marking cell junctions and the 💙 is beta-Spectrin 2 marking the mechano-sensory hair cells. These are important for the sense of balance and linear acceleration.

Boris Shraiman points a physicist’s eye on biological quandaries news.ucsb.edu/2025/022264/... 🧪

My favourite gene, Vangl2 in action

Excited to embark on this scientific journey with Ewa Paluch and Daniel StJohnston to understand fundamentals of epithelial tissue and cell shapes! Thank you to @erc.europa.eu for the support!

Ever wondered how tissues have diverse organisations? We did with some experiments on sensory epithelia of 🐣 🐟 and 🐁. We found that these epithelia are initially very similar. As they develop, cell types acquire a solid/fluid-like mechanical state driving the cellular organisation. Comments welcome!

#authorinterview Anubhav Prakash @prakash-patterns.bsky.social from Prof Raj Ladher lab earlab.bsky.social at NCBS, Bangalore talks about his work on "Kompartment Konnection: How the Cochlea Coordinates for a Perfect Design" PLOS Biology biopatrika.com/academia/res... @ncbsbangalore.bsky.social

link.growkudos.com/1efpeb7d8n4 A short article is now available at Kudos on our work @earlab.bsky.social at @ncbsbangalore.bsky.social about how the cochlea generates its pattern.

My lab @mpi-muenster.bsky.social is looking for a computational biologist with a passion for imaging and spatial biology. A staff scientist position with long-term perspective! Apply and spread the word 🙏 jobs.mpi-muenster.mpg.de/jobposting/0...

Editor's insightful commentary on our work in cochlear morphogenesis.

Our September issue is online! www.embopress.org/toc/17574684... On the cover: AAV-mediated delivery of Clic5 restores inner ear structure & function in a model of hereditary hearing and balance loss 👉 doi.org/10.1038/s443... Scientific image: R. Hahn & K. Avraham, at Tel Aviv University

We show the Organ of Corti is composed of adhesion-molecule based compartments and the interaction between these compartments (compartment coupling) drives pattern and polarity. This seems like a fundamental design principle of developing tissues.

#LatestPublication In a latest study published in PLOS Genetics, Ramankaushik and team from Dr Raj Ladher's lab describe a new role for protocadherin-15 in patterning the hair cell. 🎉Congratulations to the team! journals.plos.org/plosgenetics...

preprint: Using a combination of experiments and theory, we show that force patterning at apical junctions drives three-dimensional spatial organisation in multi-cell-type epithelia. Give us your comments!

#authorinterview Anubhav Prakash @prakash-patterns.bsky.social from Prof Raj Ladher lab @earlab.bsky.social, NCBS @ncbsbangalore.bsky.social talks about his work on "Pushing and pulling cells from chaos to order" biopatrika.com/academia/res... @natcomms.nature.com

#LatestPublication in @natcomms.nature.com by Dr Raj Ladher & team show that fine-tuned junctional mechanics are vital for aligning polarity in chicken cochlea. 🎉Congratulations to the team! @prakash-patterns.bsky.social @earlab.bsky.social Read here: www.nature.com/articles/s41...

My PhD work on the development of spatial organisation and planar polarity in avian auditory epithelia is now published @natcomms.nature.com doi.org/10.1038/s414...