🚨 New #autoinflammation #vasculitis gene alert- courtesy of @fionapk.bsky.social ! Introducing FGR 🧬 We report 3x families with pathogenic variants in HCK (2x) and ✨ for the first time ✨ FGR (1x), expanding the new class of ‘autoinflammatory Src-opathies’ ⏬️ link.springer.com/article/10.1...

Pleased to share our latest paper, a summary of many years of work with the GOSH-ACE team. An absolute pleasure to work alongside @fionapk.bsky.social and combine our PhD efforts into lasting patient benefit. academic.oup.com/rheumatology...

Congratulations to Sara Brown who, together with Alice Burleigh, has won a Pump-Priming grant award in the National Eczema Society’s first-ever grant round awards for the first structured study of topical steroid withdrawal in the UK. edin.ac/3FmhiFp

🚨 EBI has just lunched a new portal to calculate genetic scores from individual-level genetic data. Check it out 👇. It is very cool! geneticscores.org It is linked with the @pgscatalog.bsky.social This was supported by INTERVENE

A large dataset we hope is helpful for patients who may have CAPS, an #autoinflammatory condition associated with genetic variants in NLRP3. Lots of "variants of uncertain significance" now have a specific readout from our in vitro assay which can help with clinical diagnosis. rdcu.be/d9iRG

🚨 The European Animal Research Association has a vacancy for a Communications & social media officer position. Find out more about how to apply below. #jobhunt #jobopening #jobsearch #job #hiring #recruiting #commsjobs #scicomm #scicommjob #scicommjobs www.eara.eu/post/job-vac...

📢Job opportunities! We're looking for a Research Associate (Fixed Term) to join Dr Gavin Sewell on a research project investigating how #autoinflammatory conditions occur. Apply by 14 February: https://buff.ly/4aBF8rW @wellcometrust.bsky.social @uniofcam.bsky.social

What Happens When Some Cells Are More Dad Than Mom (and Vice Versa)? Latest from us. Published today. News here www.cuimc.columbia.edu/news/what-ha... article here: www.nature.com/articles/s41... @stewart_ojay @BogunovicLab and a huge international team thank you 🙏🏼

A starter pack for anyone interested in #autoinflammation and #autoinflammatory diseases. Please let me know if you’d like to be added. go.bsky.app/5M6obrp

🚨 A PhD project to develop an in vitro human implantation platform is available with me and an interdisciplinary supervisory team at the University of Sheffield. #blastoids #endometrialAssembloids #stemCellBiology #embryology #biomaterials #advancedImaging #dataScience tinyurl.com/ycykmwv4

TANK and AZI2 cooperatively sustain TBK1 activity during different stages of TNF receptor assembly to protect against autoinflammation www.nature.com/articles/s41...

www.nature.com/articles/s41... “our findings demonstrate a general mechanism involving how self-RNA structure affect innate sensors-triggering innate response and autoinflammation, and provide a potential strategy for controlling TLR-related autoimmune diseases.” #TLR7 #lupus #SLE

Academic Journals and News (Updated Dec 3, 2024) go.bsky.app/hCfhqn

I created a simple flow chart to help my lab trainees choose the most appropriate stats test in Prism (*for single-factor comparisons only). Feel free to share with your group if you think it could be helpful first start.

New starter pack for all people interested in Gene Editing & Gene Therapy 🧬✂️ including Tools & Delivery|CRISPR-Cas|Zinc finger nucleases|Viral vectors|Non-viral delivery methods go.bsky.app/8R4dVez