WESTPA fans: two new JCTC papers just landed! Great work from Michael Grabe and JC Gumbart. 👇

Come and work with us in Bristol Chemistry, ranked #1 in the UK for research. We’re seeking outstanding candidates in: Engineering biology Synthetic biology Chemical biology Biophysics or biophysical tools Biocatalysis www.bristol.ac.uk/jobs/find/de...

This is a good watch. So much potentially impactful science is being stopped for no good reason.

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WSJ story about OMB blocking NIH spending and grant making www.wsj.com/politics/pol... 1/n

Did you know about the BPS Bridging Funds Program? If you're a biophysicist navigating a difficult time, this program is for you to defray costs for attending the BPS Annual Meeting! I am grateful to the @biophysicalsoc.bsky.social for supporting our members! www.biophysics.org/2026meeting/...

Summary Table of the massive defunding of biomedical research in the United States www.nytimes.com/interactive/...

Out of the 356 drugs that were approved by the FDA from 2010-2019, NIH funding contributed to 354 of them, totaling $187 billion, only 2 were privately funded. From the NYTimes www.nytimes.com/interactive/...

Exclusive: An international scientific competition widely credited with spurring the development of artificial intelligence for biology appears to be on its deathbed. scim.ag/44ukS90

This article says all you need to know about why basic science is the lifeblood of innovation. It’s the long game but there remains no substitute. Also a favorite example of @jeremymberg.bsky.social The Radical Development of an Entirely New Painkiller www.newyorker.com/magazine/202...

ATTENTION: NSF GRANT RECIPIENTS We received a heads up from a trusted source that you should proactively download/print/screen shot any documentation on research.gov pertaining to your NSF awards, both those that are current and any that have closed in the last 5-6 years. 1/n

✨ Check out @mackevinbraza.bsky.social 's new work on full length APOBEC3B, which shows how the NTD modulates active site opening in the CTD Collab w/ @adaozlemdemir.bsky.social & Aihara, Herzik, & Harris labs pubs.acs.org/doi/10.1021/...

Great collaboration with @ltchong.bsky.social on pathway ensemble clustering. 🌟SHINE🌟 is out in @biorxiv-biophys.bsky.social : www.biorxiv.org/content/10.1..., and of course @lexinc.bsky.social got it in #MDANCE as well: github.com/mqcomplab/MD...

A behemoth effort from @fionachembot.bsky.social in which she does amazing science (showing how VOCs reshape allosteric pathways) while also making the SARS2 spike color palette match her fish Dorry 😍🫠 www.biorxiv.org/content/10.1...

@westpasoftware.bsky.social is partnering with @mdanalysis.bsky.social for Google Summer of Code this year. Please help spread the word!

Check out this excellent profile of Catherine Drennan (@drennanlab.bsky.social), Professor of Chemistry and Biology, which was recently published in PNAS: www.pnas.org/doi/10.1073/...

For those following the @prof-ajay-jain.bsky.social /Cleaves/ @wpwalters.bsky.social preprint re: DiffDock @gcorso.bsky.social I have read some of the back-&-forth between the author groups As a practitioner in the field for > 20 yrs (academic side), here is my take: 🧵

pubmed.ncbi.nlm.nih.gov/39643640/ “while AlphaFold3 shows improved performance over AlphaFold2 in predicting overall GPCR backbone architecture, significant discrepancies persist in ligand-binding poses, particularly for ions, peptides, and proteins.”

Really fortunate to have had the honor of being featured as part of NVIDIA SC24 special address by Jensen Huang and Ian Buck. This summarizes a lot of the work that is ongoing in the group highlighting the role of LLMs, multi modality and generative AI. youtu.be/eKzNKxWUeCE

Check out this bombshell publication by Michael Fischbach @mfgrp.bsky.social and coworkers @stanford-chemh.bsky.social @stanfordmedicine.bsky.social, imagine a cancer immune therapy/vaccine where treatment begins and ends with a painless topical skin treatment! 🤯 www.nature.com/articles/s41...