Looks like yet another case of overhyped results due to poor #bioMLeval evaluation of deep learning models -this time deep docking methods - specifically DiffDock. Look forward to the DiffDock authors response. But dont see any major flaws in this critique. Conclusion is REALLY worth reading!

Thanks Derek! Ann (@annclevesjain.bsky.social) and I enjoyed your summary as well as your discussion of the linkage to similar observations other high-profile deep-learning reports!